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The Antiproliferation Activity of Ganoderma formosanum Extracts on Prostate Cancer Cells

Chiang CY, Hsu KD, Lin YY, Hsieh CW, Liu JM, Lu TY, Cheng KC

Androgen-independent prostate cancer accounts for mortality in the world. In this study, various extracts of a medical fungus dubbed Ganoderma formosanum were screened for inhibition of DU145 cells, an androgen-independent...
A Retrieved Sparganum of Spirometra erinaceieuropaei from a Korean Man during Mechanical Thrombectomy

Hwang YH, Son W, Kim YW, Kang DH, Chang HH, Goo YK, Hong Y, Chung DI

Human sparganosis is a zoonotic disease caused by infection and migration of the plerocercoid of Spirometra spp. Although sparganosis were reported from most parts of the body, the sparganum parasitizing...
Causes, Risk Factors, and Clinical Outcomes of Stroke in Korean Young Adults: Systemic Lupus Erythematosus is Associated with Unfavorable Outcomes

Kwon HS, Kim YS, Lee JM, Koh SH, Kim HY, Kim C, Lee SH, Jung KH, Kim YD, Kwon HM, Kim BJ, Kim JM, Kim BJ, Heo SH, Chang DI, on Behalf of the SKY Investigators

Background and Purpose: The incidence of ischemic stroke (IS) in young adults is increasing, and the associated large socioeconomic impact makes understanding IS in young adults important. We investigated the...
Prevention and management of viral hepatitis in inflammatory bowel disease: a clinical practice guideline by the Korean Association for the Study of Intestinal Diseases

Park SK, Choi CH, Chun J, Lee H, Kim ES, Park JJ, Park CH, Lee BI, Jung Y, Park DI, Kim DY, Park H, Jeen YT, IBD Research Group of the Korean Association for the Study of Intestinal Diseases

The treatment of inflammatory bowel disease (IBD) has been revolutionized for the last 10 years by the increasing use of immunomodulators and biologics. With immunosuppression of this kind, opportunistic infection...
Risk Factors and Comorbidities Associated With the Allergic Rhinitis Phenotype in Children According to the ARIA Classification

Jung S, Lee SY, Yoon J, Cho HJ, Kim YH, Suh DI, Yang SI, Kwon JW, Jang GC, Sun YH, Woo SI, Youn YS, Park KS, Lee E, Cho HJ, Kook MH, Yi HR, Chung HL, Kim JH, Kim HY, Jung JA, Woo HO, Lee JK, Chang WS, Do NH, Cho H, Hong SJ

PURPOSE: Data are lacking on the association between the allergic rhinitis (AR) phenotype and sensitization to specific allergens or bronchial hyperresponsiveness (BHR) in children. We here investigated risk factors and...
Ten Cases of Taenia saginata Infection Confirmed by Analysis of the Internal Transcribed Spacer 1 rDNA Region in the Republic of Korea

Song SM, Yun HS, VanBik D, Chang HH, Lee SA, Kim SW, Ryoo N, Eun DY, Lee NY, Goo YK, Hong Y, Ock M, Cha HJ, Chung DI

From October 2015 to August 2018, tapeworm proglottids were obtained from 10 patients who were residents of Daegu and Gyeongbuk provinces and had a history of raw beef consumption. Most...
Clinical Characteristics of Non-Amnestic Mild Cognitive Impairment: A Single-Center Experience

Oh E, Shin CW, Kim BJ, Hwang KJ, Heo SH, Ahn TB, Chang DI, Yoon SS, Park KC, Lee JS

BACKGROUND: To evaluate the clinical characteristics of patients with non-amnestic mild cognitive impairment (naMCI) in a memory disorder clinic at a single center. METHODS: A retrospective study was conducted involving 312...
Blood Management Protocol without Transfusion in Orthopedic Surgery

Suh YS, Lee JJ, Nho JH, Chung H, Lee WS, Jang BW, Kim YB, Chun DI, Choi SW, Lee JC, Choi HS

We developed a new blood management protocol that allows patients to not undergo transfusion during major orthopaedic surgery. Here, we report the safety of or our protocol. The preoperative pharmacological...
Indoor pet ownership in infancy is a risk factor for the development of sensitization to pets and asthma in childhood

Jung S, Noh SR, Lee SY, Yoon J, Cho HJ, Kim YH, Suh DI, Yang SI, Kwon JW, Jang GC, Sun YH, Woo SI, Youn YS, Park KS, Lee E, Cho HJ, Kook MH, Yi HR, Chung HL, Kim JH, Kim HY, Jung JA, Woo HO, Hong SJ

PURPOSE: It is controversial whether indoor pet exposure is either a risk or protective factor developing sensitization to pet allergens or asthma. Therefore, we investigated whether indoor pet ownership entails...
Korean Medication Algorithm for Bipolar Disorder 2018: Comparisons with Other Treatment Guidelines

Jeong JH, Bahk WM, Woo YS, Lee JG, Kim MD, Sohn I, Shim SH, Jon DI, Seo JS, Kim W, Song HR, Min KJ, Yoon BH

The objective of this study was to compare recommendations of the Korean Medication Algorithm Project for Bipolar Disorder 2018 (KMAP-BP 2018) with other recently published guidelines for treating bipolar disorder....
Anti-Melanogenic Effect from Submerged Mycelial Cultures of Ganoderma weberianum

Lai YJ, Hsu KD, Huang TJ, Hsieh CW, Chan YH, Cheng KC

Compounds from Lingzhi has been demonstrated the ability for inhibiting tyrosinase (a key enzyme in melanogenesis) activity. In this study, we investigated the anti-melanogenic activity from the submerged mycelial culture...
Validation of Electronic Foot Function Index in Patients with Foot and Ankle Disease: A Randomized, Prospective Multicenter Study

Lee DY, Kim YM, Lee JH, Kim J, Kim JB, Kim BS, Choi GW, Seo SG, Kim JB, Park SJ, Kim YC, Choi YR, Lee DO, Cho JH, Chun DI, Kim HN, Park JY

PURPOSE: To evaluate the efficiency of the electronic foot function index (eFFI) through a prospective, random based, multi-institutional study. MATERIALS AND METHODS: The study included 227 patients ranging in age from...
A Newly-Developed Flow Diverter (FloWise) for Internal Carotid Artery Aneurysm: Results of a Pilot Clinical Study

Kim BM, Park KY, Lee JW, Chung J, Kim DJ, Kim DI

OBJECTIVE: We report the results of a pilot clinical study that evaluated the safety and efficacy of a newly-developed, retrievable flow diverter (FloWise; Taewoong Medical) for the treatment of internal...
Usefulness of Virtual Expiratory CT Images to Compensate for Respiratory Liver Motion in Ultrasound/CT Image Fusion: A Prospective Study in Patients with Focal Hepatic Lesions

Kang TW, Lee MW, Cha DI, Park HJ, Park JS, Bang WC, Kim SW

OBJECTIVE: To assess whether virtual expiratory (VE)-computed tomography (CT)/ultrasound (US) fusion imaging is more effective than conventional inspiratory (CI)-CT/US fusion imaging for hepatic interventional procedures. MATERIALS AND METHODS: This prospective study...
Surgical Strategy to Reduce the Recurrence of Adventitial Cystic Disease after Treatment

Lim JH, Chung BH, Kang JH, Heo SH, Kim DI, Kim YW, Park YJ

PURPOSE: Adventitial cystic disease (ACD) is a rare condition that causes intermittent claudication and non-atherosclerotic disease without cardiovascular risk factors. The etiology and optimal treatment of ACD remain controversial. The...
Prevalence, Risk Factors and Cutoff Values for Bronchial Hyperresponsiveness to Provocholine in 7-Year-Old Children

Jung S, Suh DI, Lee SY, Yoon J, Cho HJ, Kim YH, Yang SI, Kwon JW, Jang GC, Sun YH, Woo SI, Youn YS, Park KS, Cho HJ, Kook MH, Yi HR, Chung HL, Kim JH, Kim HY, Jung JA, Woo HO, Hong SJ

BACKGROUND: A US Food and Drug Administration (FDA)-approved drug methacholine chloride (Provocholine®) was recently introduced to Korea where it is now widely used in clinical practice. We aimed to evaluate...
Improving the Screening Instrument of Bipolar Spectrum Disorders: Weighted Korean Version of the Mood Disorder Questionnaire

Hong N, Bahk WM, Yoon BH, Min KJ, Shin YC, Jon DI

OBJECTIVE: It is not easy to diagnose bipolar disorders accurately in the clinical setting. Although Korean version of the Mood Disorder Questionnaire (K-MDQ) is easily administered, it still has weakness...
Korean Medication Algorithm for Bipolar Disorder 2018 : Maintenance Therapy

Lee JG, Bahk WM, Yoon BH, Jon DI, Seo JS, Kim W, Woo YS, Jeong JH, Kim MD, Sohn I, Shim SH, Song HR, Min KJ

OBJECTIVES: In this study, we evaluated the maintenance-treatment strategies of bipolar I and bipolar II disorders of KMAP-BP 2018. METHODS: The questionnaire used to survey experts for their opinions of medication...
Korean Medication Algorithm for Bipolar Disorder 2018 : Rapid Cycling

Jeong JH, Bahk WM, Yoon BH, Jon DI, Seo JS, Kim W, Lee JG, Woo YS, Kim MD, Sohn I, Shim SH, Song HR, Min KJ

OBJECTIVES: The objective of this study was to revise the Korean Medication Algorithm Project for Bipolar Disorder 2014 for rapid cycling. METHODS: The questionnaires, which were intended to survey experts for...
Korean Medication Algorithm for Bipolar Disorder 2018 : Mixed Features

Kim W, Bahk WM, Yoon BH, Jon DI, Seo JS, Lee JG, Jeong JH, Woo YS, Kim MD, Sohn I, Shim SH, Song HR, Min KJ

OBJECTIVES: The Korean Medication Algorithm for Bipolar Disorder 2018 (KMAP-BP 2018) has been revised again as a result of a consensus of opinions among experts. The mixed episode was changed...

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