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The Effect of Vanishing Twin on Firstand Second-Trimester Maternal Serum Markers and Nuchal Translucency: A Multicenter Prospective Cohort Study

Lee SJ, Han YJ, Kim M, Shim JY, Lee MY, Oh Sy, Lee J, Kim SH, Cha DH, Cho GJ, Kwon HS, Kim BJ, Park MH, Cho HY, Ko HS, Bae JH, Park CW, Park JS, Jun JK, Oh S, Lee DR, Ryu HM, Lee SM

Background: The purpose of this study was to evaluate the effect of vanishing twin (VT) on maternal serum marker concentrations and nuchal translucency (NT). Methods: This is a secondary analysis of...
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Cost-Effectiveness Analysis of Three Diagnostic Strategies for the Detection of EGFR Mutation in Advanced Non-Small Cell Lung Cancer

Cho SM, Lee HS, Jeon S, Kim Y, Kong SY, Lee JK, Lee KA

Background: In non-small cell lung cancer (NSCLC), epidermal growth factor receptor (EGFR) mutation testing of tumor tissue should be conducted at diagnosis. Alternatively, circulating tumor DNA can be used to...
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Efficacy Analysis of Suprapapillary versus Transpapillary Self-Expandable Metal Stents According to the Level of Obstruction in Malignant Extrahepatic Biliary Obstruction

Han SY, Lee TH, Jang SI, Kim DU, Yang JK, Cho JH, Sung MJ, Kwon CI, Park JS, Jeong S, Lee DH, Park SH, Lee DK

Background/Aims: The use of a self-expandable metal stent (SEMS) is recommended for unresectable malignant biliary obstruction (MBO). Stent-related adverse events might differ according to the position of the stent through...
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A Web-Based Decision Aid for Informed Prostate Cancer Screening: Development and Pilot Evaluation

Jung W, Cho IY, Jeon KH, Yeo Y, Jun JK, Suh M, Jeong A, Lee J, Shin DW

Background: Prostate-specific antigen-based routine screening is not recommended for the general population due to conflicting results with mortality reduction. We aimed to develop a web-based decision aid (DA) for informed...
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Clinical Trial: Efficacy of Mosapride Controlledrelease and Nortriptyline in Patients With Functional Dyspepsia: A Multicenter, Double-placebo, Double-blinded, Randomized Controlled, Parallel Clinical Study

Tae CH, Cha RR, Oh JH, Gweon TG, Park JK, Bang KB, Song KH, Huh CW, Lee JY, Shin CM, Kim JW, Youn YH, Kwon JG, Functional Dyspepsia Research Group under the Korean Society of Neurogastroenterology and Motility

  • KMID: 2550587
  • J Neurogastroenterol Motil.
  • 2024 Jan;30(1):106-115.
  • doi: 10.5056/jnm23147
Background/Aims Prokinetic agents and neuromodulators are among the treatment options for functional dyspepsia (FD), but their comparative efficacy is unclear. We aimed to compare the efficacy of mosapride controlled-release (CR) and...
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A Case Report of Primary Sjögren’s Syndrome Presenting Oral Mucosal Pain

Lee JY, Byun JS, Jung JK, Choi JK

Sjögren’s syndrome (SS) is an autoimmune rheumatic disease characterized by the presence of lymphocytic infiltration of exocrine glands and other organs. Due to the rarity of SS, it is frequently...
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Clinical Practice Guideline for Stroke Rehabilitation in Korea—Part 1: Rehabilitation for Motor Function (2022)

Kim DY, Ryu B, Oh BM, Kim DY, Kim DS, Kim DY, Kim DK, Kim EJ, Lee HY, Choi H, Kim HS, Lee HH, Kim HJ, Oh HM, Seok H, Park J, Park J, Park JG, Kim JM, Lee J, Shin JH, Lee JK, Oh JS, Park KD, Kim KT, Chang MC, Chun MH, Kim MW, Kang MG, Song MK, Choi M, Ko MH, Kim NY, Paik NJ, Jung SH, Yoon SY, Lim SH, Lee SJ, Yoo SD, Lee SH, Yang SN, Park SW, Lee SY, Han SJ, Lee SJ, Bok SK, Ohn SH, Im S, Pyun SB, Hyun SE, Kim SH, Ko SH, Jee S, Kwon S, Kim TW, Chang WH, Chang WK, Yoo WK, Kim YH, Yoo YJ, Kim YW, Shin YI, Park YG, Choi YH, Kim Y, KSNR Stroke CPG Writing Group

This clinical practice guideline (CPG) is the fourth edition of the Korean guideline for stroke rehabilitation, which was last updated in 2016. The development approach has been changed from a...
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Efficacy of Olaparib in Treatment-Refractory, Metastatic Breast Cancer with Uncommon Somatic BRCA Mutations Detected in Circulating Tumor DNA

Yoon JK, Ahn J, Kim S, Kim HP, Kang Jk, Bang D, Lim Y, Kim TY

Poly(ADP-ribose) polymerase inhibitors have been shown dramatic responses in patients with BRCAness. However, clinical studies have been limited to breast cancer patients with germline mutations. Here, we describe a patient...
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Treatment outcome and prognostic factors in relapsed pediatric acute myeloid leukemia

Lee JH, Ju HY, Hyun JK, Kim SJ, Cho HW, Lee JK, Lee JW, Sung KW, Yoo KH

Background Despite improved outcomes for pediatric patients with acute myeloid leukemia (AML), the prognosis for relapse remains poor. This study aimed to examine the clinical factors associated with prognosis in relapsed...
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Imaging Characteristics of Idiopathic Myointimal Hyperplasia of the Mesenteric Veins: Diagnostic Insights

Park R, Jang JK, Kim HJ, Kim J, Lim SB

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Tibolone and Breast Cancer

Lee JK, Yun H, Kim H, Yun BH, Seo SK

Tibolone, a selective tissue estrogenic activity regulator, is a synthetic steroid with distinct pharmacological and clinical characteristics in contrast to conventional menopausal hormone therapy. Tibolone induces estrogenic activity in the...
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Exploring the role of copine 1 in human colorectal cancer: investigating its association with tumorigenesis and metastasis

Lee JK, Lee SJ, Hah YS, Ji YH, Ju YT, Lee YJ, Jeong CY, Kim JY, Park JH, Kim JM, Cho JK, Kim HG, Kwag SJ

Purpose: This study aimed to investigate the potential role of copine-1 (CPNE1), a calcium-dependent membrane-binding protein encoded by the CPNE1 gene, in colorectal cancer (CRC). Despite previous research on the...
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A Rare Case of Peritoneal Dialysis-Related Peritonitis Caused by Paracoccus yeei

Kim JK, Shin JS, Cha YJ, Chung BH, Yoo IY, Park YJ

Paracoccus yeei is rare, opportunistic pathogen which can cause various diseases. Here, we report a case of peritonitis caused by P . yeei, which was successfully treated with cefazolin and...
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Evaluation of the Efficacy and Safety of DW1903 in Patients with Gastritis: A Randomized, Double-Blind, Noninferiority, Multicenter, Phase 3 study

Kim JH, Jung HY, Yoo IK, Park SY, Kim JG, Sung JK, Jang JS, Cheon GJ, Kim KO, Kim TO, Lee ST, Cho KB, Chun HJ, Park JJ, Park MI, Jang JY, Jeon SW, Cho JW, Kang DH, Kim GH, Kim JJ, Kim SG, Kim N, Lee YC, Hong SJ, Kim HS, Lee S, Lee SW

Background/Aims: H2 receptor antagonists (H2RA) have been used to treat gastritis by inhibiting gastric acid. Proton pump inhibitors (PPIs) are more potent acid suppressants than H2RA. However, the efficacy and safety...
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Sleep hygiene education in orofacial pain patients

Kang JK, Lee JH

The importance of sleep medicine has emerged recently as it is well-known now that sleep health affects the onset and progression of various systemic diseases. Sleep-breathing disorders, such as snoring...
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Rehabilitation using endocrown for fracture of maxillary anterior teeth due to trauma in adolescence: a case report

Lee SY, Son SA, Park JK

Complicated crown fractures of maxillary anterior teeth caused by trauma in adolescence can cause functional and aesthetic problems. For crown fractures with pulp exposure, various restorative methods can be considered...
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Lineage Switch Subsequently Developed after Isolated Extramedullary Relapse in Children with Acute Myeloid Leukemia

Park YR, Yang EJ, Hyun JK, Jeong I, Kim IS, Lim YT

Isolated extramedullary relapse (EMR) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) in acute myeloid leukemia (AML) is relatively rare and the clinical significance is still not well characterized, particularly in...
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Hypersensitivity reactions to ibuprofen and acetaminophen: A report of case with literature review

Yoo MJ, Lee HS, Park JS, Kim JK

The higher the use of nonsteroidal anti-inflammatory drugs (NSAIDs), the more reports of adverse drug reactions, especially in children than in adults. As patients with fever take several NSAIDs alternatively,...
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Impact of denosumab on aortic arch calcification in kidney transplant recipients

Park WY, Yang J, Kwon JK, Lee HJ, Kim Y, Paek JH, Jin K, Han S

Background: Aortic arch calcification (AoAC) is associated with cardiovascular disease in kidney transplant recipients (KTRs). Recent research reported that Denosumab, a potent antiresorptive agent, might affect to AoAC in hemodialysis...
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Successful treatment of hemophagocytic lymphohistiocytosis in a patient with systemic lupus erythematosus with ruxolitinib: a case report

Jung JI, Kim JY, Kim MH, Park JK, Lee EY, Lee EB, Park JW

Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening hematological disorder characterized by uncontrolled activation of CD8+ T and natural killer cells, leading to a cytokine storm and severe organ dysfunction. Although...
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