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Expression of insulin-like growth factorIGF-II and IGF binding proteinIGFBP-1 in preeclamptic placentas

Park CH, Yoo YO, Lee JH, Yang DE, Jung DY, Baek EJ, Moon HB, Shin JC, Kim CY, Kim SP

  • KMID: 2036208
  • Korean J Obstet Gynecol.
  • 2000 Dec;43(12):2263-2268.
No abstract available.
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Expression of Hepatocyte Growth Factor and its receptor in Placentas of Mild and Severe Preeclampsia

Lee JH, Shin JC, Jung DY, Baek EJ, Moon HB, Yang DE, Kim SJ, Kim CY, Kim SP

  • KMID: 1568993
  • Korean J Obstet Gynecol.
  • 2000 Aug;43(8):1444-1449.
No abstract available.
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Analysis of gene expression in placenta of severe preeclampsia

Lee GS, Lee Y, Yang DE, Shin JC

  • KMID: 2280796
  • Korean J Perinatol.
  • 2008 Dec;19(4):341-350.
OBJECTIVE: This study was designed to detect genes specifically expressed in severe preeclamptic placentas. METHODS: Placenta tissues were collected immediately after delivery from 5 preeclamptic patients and 5 normal pregnant women....
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Gene Expression of Vascular Endothelial Growth Factor(VEGF) and Placental Growth Factor(PlGF) in Human Placenta

Shin JC, Lee Y, Chung DY, Baik EJ, Oh MJ, Yang DE, Kim SJ, Kim CE, Kim SP

  • KMID: 2269741
  • Korean J Obstet Gynecol.
  • 1999 Aug;42(8):1677-1682.
OBJECTIVE: To determine whether gene expressions of VEGF and PlGF are different between the human placenta of normal and abnormal pregnancy. METHODS: Placenta was collected at each trimester of normal...
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ATP and Adenosine Induce Growth Inhibition and Apoptosis in Human Trophoblast-like (TL) Cell Line

Park IY, Lee JH, Lee KH, Yang DE, Moon HB, Kim SJ, Shin JC

  • KMID: 2272036
  • Korean J Obstet Gynecol.
  • 2003 May;46(5):952-956.
BACKGROUND: Although nucleotides -like Adenosine Triphosphate (ATP) and its derivatives Adenosine, were known to induce growth inhibition and apoptosis in diverse cell lines, little is known about their effects on...
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Differential Gene Expression in Placenta of Term Pregnant Women with and without Labor using cDNA Microarray

Kim A, Kim OK, Seo MW, Yang DE, Ahn HY, Park IY, Lee GS, Shin JC

  • KMID: 2280612
  • Korean J Perinatol.
  • 2007 Dec;18(4):370-377.
OBJECTIVE:cDNA microarray technology was used to comprehensively analyze the gene expression in the placenta of term women with labor compared to without labor. METHODS:Placental tissue was obtained from patients in spontaneous...
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Association of the polymorphisms in CYP1A1 and CYP1A2 genes with preterm premature rupture of membranes

Park CH, Shin JC, Yang DE, Park IY, Ko HS, Kim YH, Ahn HY, Kim SJ, Kim SP

  • KMID: 2272461
  • Korean J Obstet Gynecol.
  • 2004 Dec;47(12):2319-2324.
OBJECTIVE: Preterm delivery (PTD) is the leading cause of perinatal mortality and morbidity. However, its etiology and pathogenesis remain unknown in most cases. Recently, some research put forth the hypothesis...
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Influence of Hypoxic Condition on Invasion of Cultured Trophoblast

Baik EJ, Shin JC, Jung DY, Yang DE, Kim JD, Rho SH, Lee JS, Kim SJ, Kim CI, Kim SP

  • KMID: 2072005
  • Korean J Perinatol.
  • 1999 Dec;10(4):498-507.
OBJECTIVE: To investigated whether lowering oxygen tension affects invasion of cultured trophoblast. METHODS: Trophoblasts were isolated from the normal placenta in early pregnancy(6-10 weeks in gestation). Isolated trophoblasts were cultured...
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Role of Cyclooxygense-2 in Lipopolysacharide induced Matrix Metalloproteinase-2 and -9 expressions in human trophoblast (TL) cell line

Lee JH, Shin JC, Ahn HY, Yang DE, Kwon I, Lee GS, Kim SP

  • KMID: 2128997
  • Korean J Obstet Gynecol.
  • 2002 Oct;45(10):1752-1757.
OBJECTIVE: To evaluate whether lipopolysaccharide (LPS) modulates the expression of cyclooxy- genase-2 (COX-2) and also whether COX-2 is involved in the LPS induced matrix metalloproteinase-2 (MMP-2) and MMP-9 activation in...
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Expression of Tissue Tissue-transglutaminase-2 (TGM2) and Cyclo-oxygenase (COX) in the Fetal Membrane of Preterm Birth

Park IY, Yang DE, Kim YH, Kwon JY, Ahn HY, Lee Y, Lee G, Kim SJ, Shin JC

  • KMID: 2280601
  • Korean J Perinatol.
  • 2007 Jun;18(2):154-162.
BACKGROUND: Preterm labor accounts for one third of preterm deliveries. However, the causes and the mechanism of preterm labor are still under investigation. The purpose of this study was to...
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Differential gene expression of transglutaminase 2 in term pregnancy with and without labor

Kim OK, Kim A, Seo MW, Ahn HY, Yang DE, Lee GS, Shin JC

  • KMID: 2273344
  • Korean J Obstet Gynecol.
  • 2008 May;51(5):510-517.
OBJECTIVE: Our purpose was to investigate transglutaminase 2 (TGM2) mRNA and protein expressions in term placentas and fetal membranes delivered with labor compared to no labor. METHODS: Samples were obtained from...
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Role of nitric oxide and interleukin-1beta on expression of matrix metalloproteinase-2 in TL cell line

Lee JD, Shin JC, Yang DE, Moon HB, Lee JH, Ahn HY, Lee GS, Kim SJ, Kim SP

  • KMID: 2270632
  • Korean J Obstet Gynecol.
  • 2002 Dec;45(12):2225-2230.
OBJECTIVE: We studied to investigate whether nitric oxide (NO) and IL-1beta modulate MMP-2 and MMP-9 using TL cell line obtained from the normal term placenta. METHODS: After culturing TL cell...
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Influence of Hypoxia on Vascular Endothelial Growth Factor and Basic Fibroblast Growth Factor in Cultured Human Trophoblast

Lee Y, Shin JC, Yang DE, Moon HB, Lee GS, Kim SJ, Lee JS, Kim CE, Kim SP

  • KMID: 2076851
  • Korean J Obstet Gynecol.
  • 2003 Mar;46(3):617-623.
OBJECTIVE: To investigate whether the hypoxic condition influences on the expression of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) mRNA in the cultured human trophoblast. METHODS: Trophoblasts...
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Analysis of Gene Expression in the Human Chorion of Preterm Labor Using cDNA Microarray

Ko HS, Kim YH, Kil KC, Yang DE, Park IY, Kim SJ, Park TC, Shin JC

  • KMID: 2280571
  • Korean J Perinatol.
  • 2006 Jun;17(2):204-216.
OBJECTIVE: We used a genome-wide approach to identify differentially expressed genes in patients with preterm delivery caused by preterm labor to improve the understanding of underlying molecular mechanism. METHODS: RNA...
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Influence of Hepatocyte Growth Factor on its Receptor (c-met) expression and Invasion in HT Cell Line

Shin JC, Lee JH, Yang DE, Oh MJ, Moon HB, Lee Y, Kim SJ, Yi CS, Kim SP

  • KMID: 2262351
  • Korean J Obstet Gynecol.
  • 2001 Aug;44(8):1507-1513.
OBJECTIVE: To evaluate the invasive capacity of trophoblastic cells when treated with HGF, and see whether HGF induces c-met expression in vitro. METHODS: HT cell line was treated with recombinant HGF...
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Influence of Hepatocyte Growth Factor on Matrix Metalloproteinase Expression in HT cell line

Shin JC, Moon HB, Lee JH, Yang DE, Lee G, Lee Y, Lee JS, Kim CY, Kim SP

  • KMID: 2262480
  • Korean J Obstet Gynecol.
  • 2001 Dec;44(12):2257-2262.
OBJECTIVE: This study was performed to investigate the influence of hepatocyte growth factor (HGF) on matrix metalloproteinase (MMP), which are related in the lysis process of tissue during the invasion...
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Search for Differentially Expressed Genes in Preterm Human Placentae and Their Membranes by Annealing Control Primer System

Ko HS, Kim YH, Kil KC, Jeong JH, Yang DE, Chung DY, Park TC, Kim SP, Shin JC

  • KMID: 2072119
  • Korean J Perinatol.
  • 2005 Dec;16(4):300-308.
OBJECTIVE: The aim of this study was to investigate the gene expression profiles using GeneFishingTM kit in human placentae and their membranes delivered at preterm caused by preterm labor. METHODS: Specimens...
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