- SUV39H1 is a New Client Protein of Hsp90 Degradated by Chaetocin as a Novel C-Terminal Inhibitor of Hsp90
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Lian B, Lin Q, Tang W, Qi X, Li J
- KMID: 2510127
- Biomol Ther.
- 2021 Jan;29(1):73-82.
- doi: 10.4062/biomolther.2020.012
Hsp90 is often overexpressed with activated form in cancer cells, and many key cellular proteins are dependent upon the Hsp90 machinery (these proteins are called “client protein”). Nowadays, more client... -
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- Does adenocarcinoma have a worse prognosis than squamous cell carcinoma in patients with cervical cancer? A real-world study with a propensity score matching analysis
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Pan X, Yang W, Wen Z, Li F, Tong L, Tang W
- KMID: 2512050
- J Gynecol Oncol.
- 2020 Nov;31(6):e80.
- doi: 10.3802/jgo.2020.31.e80
Objective: To compare survival outcomes between cervical adenocarcinoma (ADC) and squamous cell carcinoma (SCC) using a propensity score matching (PSM) analysis based on the Surveillance, Epidemiology, and End Results (SEER)... -
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- β1,4-Galactosyltransferase V Modulates Breast Cancer Stem Cells through Wnt/β-catenin Signaling Pathway
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Tang W, Li M, Qi X, Li J
- KMID: 2507935
- Cancer Res Treat.
- 2020 Oct;52(4):1084-1102.
- doi: 10.4143/crt.2020.093
Purpose Breast cancer stem cells (BCSCs) contribute to the initiation, development, and recurrence of breast carcinomas. β1,4-Galactosyltransferase V (B4GalT5), which catalyzes the addition of galactose to GlcNAcβ1-4Man of N-glycans, is involved... -
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- A new strategy for stem cells therapy for erectile dysfunction: Adipose-derived stem cells transfect Neuregulin-1 gene through superparamagnetic iron oxide nanoparticles
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Cheng J, Zheng Z, Tang W, Shao J, Jiang H, Lin H
- KMID: 2529363
- Investig Clin Urol.
- 2022 May;63(3):359-367.
- doi: 10.4111/icu.20220016
Purpose: Our previous studies showed that nanotechnology improves derived adipose-derived stem cells (ADSCs) therapy for erectile dysfunction (ED). In this study, the Neuregulin-1(NRG1) gene was transfected into ADSCs with superparamagnetic... -
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- Enteric dysbiosis-linked gut barrier disruption triggers early renal injury induced by chronic high salt feeding in mice
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Hu J, Luo H, Wang J, Tang W, Lu J, Wu S, Xiong Z, Yang G, Chen Z, Lan T, Zhou H, Nie J, Jiang Y, Chen P
- KMID: 2389298
- Exp Mol Med.
- 2017 Aug;49(8):e370.
- doi: 10.1038/emm.2017.122
Chronic high-salt diet-associated renal injury is a key risk factor for the development of hypertension. However, the mechanism by which salt triggers kidney damage is poorly understood. Our study investigated... -
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- Impaired Delta NP63 Expression is Associated with Poor Tumor Development in Transitional Cell Carcinoma of the Bladder
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He Y, Wu X, Tang W, Tian D, Luo C, Yin Z, Du H
- KMID: 1783068
- J Korean Med Sci.
- 2008 Oct;23(5):825-832.
- doi: 10.3346/jkms.2008.23.5.825
The oncogenic isoform of the p63 protein, delta NP63, plays an important role in the pathogenesis of many epithelial carcinomas, and emerging evidences suggest that delta NP63 is a promising... -
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- miR-148b-3p, miR-190b, and miR-429 Regulate Cell Progression and Act as Potential Biomarkers for Breast Cancer
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Dai W, He J, Zheng L, Bi M, Hu F, Chen M, Niu H, Yang J, Luo Y, Tang W, Sheng M
- KMID: 2450117
- J Breast Cancer.
- 2019 Jun;22(2):219-236.
- doi: 10.4048/jbc.2019.22.e19
PURPOSE: Breast cancer is the most frequently diagnosed malignancy in women worldwide. MicroRNAs (miRNAs) are thought to serve as potential biomarkers in various cancers, including breast cancer. METHODS: We evaluated the... -
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- In Vivo Assessment of Neurodegeneration in Type C Niemann-Pick Disease by IDEAL-IQ
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Guo RM, Li QL, Luo ZX, Tang W, Jiao J, Wang J, Kang Z, Chen SQ, Zhang Y
- KMID: 2425114
- Korean J Radiol.
- 2018 Feb;19(1):93-100.
- doi: 10.3348/kjr.2018.19.1.93
OBJECTIVE: To noninvasively assess the neurodegenerative changes in the brain of patients with Niemann-Pick type C (NPC) disease by measuring the lesion tissue with the iterative decomposition of water and... -
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- Automatic Detection and Classification of Rib Fractures on Thoracic CT Using Convolutional Neural Network: Accuracy and Feasibility
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Zhou QQ, Wang J, Tang W, Hu ZC, Xia ZY, Li XS, Zhang R, Yin X, Zhang B, Zhang H
- KMID: 2503242
- Korean J Radiol.
- 2020 Jul;21(7):869-879.
- doi: 10.3348/kjr.2019.0651
Objective: To evaluate the performance of a convolutional neural network (CNN) model that can automatically detect and classify rib fractures, and output structured reports from computed tomography (CT) images. Materials and... -
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- The association between new generation oral contraceptive pill and the development of inflammatory bowel diseases
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Sanagapalli S, Ko Y, Kariyawasam V, Ng SC, Tang W, de Silva H, Chen M, Wu K, Aniwan S, Ng KK, Ong D, Ouyang Q, Hilmi I, Simadibrata M, Pisespongsa P, Gopikrishna S, Leong RW, on behalf of the IBD Sydney Organisation and the Asia-Pacific Crohn's and Colitis Epidemiology Study (ACCESS) Group
- KMID: 2417653
- Intest Res.
- 2018 Jul;16(3):409-415.
- doi: 10.5217/ir.2018.16.3.409
BACKGROUND/AIMS: To examine the association between use of oral contraceptive pills (OCPs) and the risk of developing inflammatory bowel diseases (IBD), in a modern cohort. METHODS: A prospective nested case-control study... -
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