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Hesperetin Stimulates Cholecystokinin Secretion in Enteroendocrine STC-1 Cells

Kim HY, Park M, Kim K, Lee YM, Rhyu MR

  • KMID: 1502513
  • Biomol Ther.
  • 2013 Mar;21(2):121-125.
Hesperetin (3',5,7-trihydroxy 4'-methoxyflavanone) and its glycoside hesperidin (hesperetin 7-rhamnoglucoside) in oranges have been reported to possess pharmacological effects related to anti-obesity. However, hesperetin and hesperidin have not been studied on...
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Naringenin stimulates cholecystokinin secretion in STC-1 cells

Park M, Kim K, Lee YM, Rhyu MR, Kim HY

  • KMID: 2313722
  • Nutr Res Pract.
  • 2014 Apr;8(2):146-150.
BACKGROUND/OBJECTIVES: Cholecystokinin (CCK), a hormone or neuropeptide, is secreted in response to intraluminal nutrients by enteroendocrine I-cells of the intestine and has important physiological actions related to appetite regulation and...
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Differences in Taste Thresholds According to Sex and Age Groups in Korean

Lee JW, Son HJ, Shin SH, Rhyu MR, Kim JY, Ye MK

BACKGROUND AND OBJECTIVES: The aim of the study was to compare the gustatory function between age-matched men and women in Korean subjects. SUBJECTS AND METHOD: Healthy non-smoking volunteers without smell and...
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c-Fos Expression in the Nucleus of the Solitary Tract in Response to Salt Stimulation in Rats

Kwak Y, Rhyu MR, Bai SJ, Sa YH, Kwon MJ, Lee BH

Salt signals in tongue are relayed to the nucleus of the solitary tract (NST). This signaling is very important to determine whether to swallow salt-related nutrition or not and suggests...
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A Comparative Study of Whole-Mouth Taste Thresholds between North Korean Refugees and South Koreans

Kim EY, Kim Y, Lee Y, Rhyu MR

BACKGROUND AND OBJECTIVES: Since Korea has been divided into two countries over 60 years ago and differences has gradually developed between the two, an influx of North Korean refugees to...
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The Effect of Aging on Taste Thresholds in Korean

Lee JW, Shin SH, Rhyu MR, Kim JY, Ye MK

BACKGROUND AND OBJECTIVES: The sense of taste is one of the most important human senses and plays a critical role in an individual's food preferences and the nutritional status. Proper...
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Comparison of Salt Taste Threshold and Salt Intake between Hypertensive and Normotensive Group

Son HJ, Ko JJ, Shin SH, Lee YS, Kim JY, Rhyu MR, Ye MK

BACKGROUND AND OBJECTIVES: Salt-taste threshold can influence salt appetite, and is thought to be another marker of sodium intake. Many studies have found an association between sodium intake and blood...
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Relationship between Taste Genotype and Smoking and Alcohol Intake

Ye MK, Han BD, Lee JW, Rhyu MR, Hyun DS, Shin SH

BACKGROUND AND OBJECTIVES: Genetic variations of bitter taste receptors (TAS2R) have shown different responses to bitter taste compounds and the frequencies of these variations were different within and between populations....
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The Relationship between Single Nucleotide Polymorphisms of the Carbonic Anhydrase 6 Gene andPhenylthiocarbamide Taste Sensitivity, Taste Disorder

Bae JW, Kim UK, Oh SK, Rhyu MR, Shin SH, Ye MK

BACKGROUND AND OBJECTIVES: The phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) taste sensitivity varies among individuals. Recently, it is reported that PROP taste responsiveness is associated with carbonic anhydrase 6 (CA6) gene...
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Effect of Korean Native Cimicifuga Species on Proliferation of Vascular Smooth Muscle Cells

Kang YH, Lee DY, Choi DS, Yoon BK, Lee YJ, Rhyu MR

  • KMID: 2365473
  • J Korean Soc Menopause.
  • 2012 Aug;18(2):100-105.
OBJECTIVES: To examine the effect of extracts of Korean native Cimicifuge species on cell proliferation in vascular smooth muscle cells (VSMC). METHODS: VSMC were isolated from rat aorta. Cell proliferation was...
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Cytotoxic Effects of Lysophosphatidylcholine on Vascular Smooth Muscle Cells

Lee DY, Kang YH, Choi DS, Lee YJ, Rhyu MR, Yoon BK

  • KMID: 2321326
  • J Korean Soc Menopause.
  • 2012 Dec;18(3):139-146.
OBJECTIVES: To investigate the cytotoxic effects of lysophosphatidylcholine (lysoPC), an active component of oxidized low-density lipoproteins (LDL), on vascular smooth muscle cells (VSMCs). METHODS: VSMCs were derived from rat aorta. Cell...
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Impact of Lysophosphatidylcholine on the Plasminogen Activator System in Cultured Vascular Smooth Muscle Cells

Yoon BK, Kang YH, Oh WJ, Park K, Lee DY, Choi D, Kim DK, Lee Y, Rhyu MR

The balance between tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor type 1 (PAI-1) regulates fibrinolysis. PAI-1 expression increases in atherosclerotic arteries and vascular smooth muscle cells (VSMCs) are one...
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