- The Discovery of Clinically Applicable Biomarkers for Bipolar Disorder: A Review of Candidate and Proteomic Approaches
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Muneer A
- KMID: 2506826
- Chonnam Med J.
- 2020 Sep;56(3):166-179.
- doi: 10.4068/cmj.2020.56.3.166
Bipolar disorder (BD) is a severe psychiatric condition which affects innumerable people across the globe. The etiopathogenesis of BD is multi-faceted with genetic, environmental and psychosocial factors playing a role.... -
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- Bipolar Disorder: Role of Inflammation and the Development of Disease Biomarkers
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Muneer A
- KMID: 2316593
- Psychiatry Investig.
- 2016 Jan;13(1):18-33.
- doi: 10.4306/pi.2016.13.1.18
Bipolar disorder is a severe and enduring psychiatric condition which in many cases starts during early adulthood and follows a relapsing and remitting course throughout life. In many patients the... -
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- The Staging of Major Mood Disorders: Clinical and Neurobiological Correlates
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Muneer A, Mazommil R
- KMID: 2419363
- Psychiatry Investig.
- 2018 Aug;15(8):747-758.
- doi: 10.30773/pi.2018.05.26
OBJECTIVE: Staging of psychiatric disorders is gaining momentum and the purpose of this review is to examine whether major mood disorders can be defined according to stages. METHODS: In April 2018... -
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- Wnt and GSK3 Signaling Pathways in Bipolar Disorder: Clinical and Therapeutic Implications
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Muneer A
- KMID: 2378478
- Clin Psychopharmacol Neurosci.
- 2017 May;15(2):100-114.
- doi: 10.9758/cpn.2017.15.2.100
The neurobiology of bipolar disorder, a chronic and systemic ailment is not completely understood. The bipolar phenotype manifests in myriad ways, and psychopharmacological agents like lithium have long term beneficial... -
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- Aripiprazole in the Treatment of Refractory Mood Disorders: A Case Series
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Muneer A
- KMID: 2279948
- Clin Psychopharmacol Neurosci.
- 2014 Aug;12(2):157-159.
Major depressive disorder and bipolar disorders are among the commonest neuropsychiatric conditions, affecting persons of both sexes which belong to all age groups. Comorbidity is the rule rather than the... -
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- Staging Models in Bipolar Disorder: A Systematic Review of the Literature
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Muneer A
- KMID: 2170980
- Clin Psychopharmacol Neurosci.
- 2016 May;14(2):117-130.
- doi: 10.9758/cpn.2016.14.2.117
Bipolar disorder is manifested as severe dysregulation of mood with recurrent manic and major depressive episodes. It is associated with psychiatric and medical comorbidities, inadequate response to currently available pharmacological... -
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- The Neurobiology of Bipolar Disorder: An Integrated Approach
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Muneer A
- KMID: 2152653
- Chonnam Med J.
- 2016 Jan;52(1):18-37.
- doi: 10.4068/cmj.2016.52.1.18
Bipolar disorder is a heterogeneous condition with myriad clinical manifestations and many comorbidities leading to severe disabilities in the biopsychosocial realm. The objective of this review article was to underline... -
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- Pharmacotherapy of Bipolar Disorder with Quetiapine: A Recent Literature Review and an Update
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Muneer A
- KMID: 2171062
- Clin Psychopharmacol Neurosci.
- 2015 Apr;13(1):25-35.
- doi: 10.9758/cpn.2015.13.1.25
Bipolar disorder is a chronic, recurrent condition with the usual onset during adolescence or early adulthood. In the Diagnostic and Statistical Manual of Mental Disorders 5th edition, it is conceptualized... -
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- Kynurenine Pathway of Tryptophan Metabolism in Neuropsychiatric Disorders: Pathophysiologic and Therapeutic Considerations
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Muneer A
- KMID: 2508977
- Clin Psychopharmacol Neurosci.
- 2020 Nov;18(4):507-526.
- doi: 10.9758/cpn.2020.18.4.507
Under physiological conditions 95% of the ingested essential amino acid tryptophan is metabolized by the kynurenine pathway (KP) to yield the ubiquitous co-enzyme nicotinamide adenine dinucleotide, fulfilling cellular energy requirements.... -
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- Mixed States in Bipolar Disorder: Etiology, Pathogenesis and Treatment
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Muneer A
- KMID: 2367335
- Chonnam Med J.
- 2017 Jan;53(1):1-13.
- doi: 10.4068/cmj.2017.53.1.1
Many bipolar disorder patients exhibit mixed affective states, which portend a generally more severe illness course and treatment resistance. In the previous renditions of Diagnostic and Statistical Manual mixed states... -
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- Pharmacotherapy of Acute Bipolar Depression in Adults: An Evidence Based Approach
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Muneer A
- KMID: 2235103
- Korean J Fam Med.
- 2016 May;37(3):137-148.
- doi: 10.4082/kjfm.2016.37.3.137
In the majority of cases of bipolar disorder, manic episodes are usually brief and typically responsive to currently available psychopharmacological agents. In contrast, depressive manifestations are more prevalent and persistent,... -
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- Telomere Biology in Mood Disorders: An Updated, Comprehensive Review of the Literature
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Muneer A, Minhas FA
- KMID: 2457398
- Clin Psychopharmacol Neurosci.
- 2019 Aug;17(3):343-363.
- doi: 10.9758/cpn.2019.17.3.343
Major psychiatric disorders are linked to early mortality and patients afflicted with these ailments demonstrate an increased risk of developing physical diseases that are characteristically seen in the elderly. Psychiatric... -
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- Endoplasmic Reticulum Stress: Implications for Neuropsychiatric Disorders
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Muneer A, Shamsher Khan RM
- KMID: 2432250
- Chonnam Med J.
- 2019 Jan;55(1):8-19.
- doi: 10.4068/cmj.2019.55.1.8
The Endoplasmic reticulum (ER), an indispensable sub-cellular component of the eukaryotic cell carries out essential functions, is critical to the survival of the organism. The chaperone proteins and the folding... -
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- The British Society for Sexual Medicine Guidelines on Male Adult Testosterone Deficiency, with Statements for Practice
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Hackett G, Kirby M, Rees RW, Jones TH, Muneer A, Livingston M, Ossei-Gerning N, David J, Foster J, Kalra PA, Ramachandran S
- KMID: 2543302
- World J Mens Health.
- 2023 Jul;41(3):508-537.
- doi: 10.5534/wjmh.221027
Testosterone deficiency (TD) is an increasingly common problem with significant health implications, but its diagnosis and management can be challenging. A multi-disciplinary panel from BSSM reviewed the available literature on... -
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