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A Novel e8a2BCR-ABL1 Fusion Transcript without Insertion Sequence in a Patient with Chronic Myeloid Leukemia

Jin C, Zhu X, Xiao M, Liu S, Liu X, Liu J, Xu X, Yi S, Meng L

No abstract available.
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Hydrogen sulfide alleviates hypothyroidism-induced myocardial fibrosis in rats through stimulating autophagy and inhibiting TGF-β1/Smad2 pathway

Song X, Nie L, Long J, Zhao J, Liu X, Wang L, Liu D, Wang S, Liu S, Yang J

Hypothyroidism alone can lead to myocardial fibrosis and result in heart failure, but traditional hormone replacement therapy does not improve the fibrotic situation. Hydrogen sulfide (H 2 S), a new...
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Identification and characterization of atypical porcine pestivirus genomes in newborn piglets with congenital tremor in China

Shen H, Liu X, Zhang P, Wang L, Liu Y, Zhang L, Liang P, Song C

Recently, a novel atypical porcine pestivirus (APPV) in pig was reported. In this study, two APPV strains, APPV-China/GZ01/2016 (GZ01) and APPV-China/GD-SD/2016 (GD-SD), were identified in two newborn piglet herds with...
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Fasting Blood Glucose, Cholesterol, and Risk of Primary Liver Cancer: The Kailuan Study

Ma X, Cui H, Sun M, Liu Q, Liu X, Li G, Wei Y, Fu Q, Liu S, Cao L

Purpose The influence of fasting blood glucose (FBG) and cholesterolemia primary liver cancer (PLC) in china was analyzed via a large prospective cohort study based on a community population, and the...
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Comparative imaging of ectopic mediastinal parathyroid adenoma with magnetic resonance imaging and single photon emission computed tomography/computed tomography: advantages of multimodality imaging

Liu X, Meng Z, Wang P, Jia Q

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Cadmium induces apoptosis in primary rat osteoblasts through caspase and mitogen-activated protein kinase pathways

Zhao H, Liu W, Wang Y, Dai N, Gu J, Yuan Y, Liu X, Bian J, Liu ZP

Exposure to cadmium (Cd) induces apoptosis in osteoblasts (OBs); however, little information is available regarding the specific mechanisms of Cd-induced primary rat OB apoptosis. In this study, Cd reduced cell...
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Cerebrospinal Fluid Leakage after Surgeries on the Thoracic Spine: A Review of 362 Cases

Hu P, Yu M, Liu X, Liu Z, Jiang L, Wei F, Chen Z

STUDY DESIGN: A retrospective clinical review. PURPOSE: To describe the incidence of cerebrospinal fluid leakage (CSFL) after thoracic decompression and examine the CSFL predisposing clinical factors. OVERVIEW OF LITERATURE: CSFL is a...
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CRM1 inhibitor S109 suppresses cell proliferation and induces cell cycle arrest in renal cancer cells

Liu X, Chong Y, Liu H, Han Y, Niu M

Abnormal localization of tumor suppressor proteins is a common feature of renal cancer. Nuclear export of these tumor suppressor proteins is mediated by chromosome region maintenance-1 (CRM1). Here, we investigated...
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N-acetylcysteine protects against cadmium-induced oxidative stress in rat hepatocytes

Wang J, Zhu H, Liu X, Liu Z

Cadmium (Cd) is a well-known hepatotoxic environmental pollutant. We used rat hepatocytes as a model to study oxidative damage induced by Cd, effects on the antioxidant systems, and the role...
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Involvement of the Ca2+ signaling pathway in osteoprotegerin inhibition of osteoclast differentiation and maturation

Fu Y, Gu J, Wang Y, Yuan Y, Liu X, Bian J, Liu ZP

The purpose of this study was to determine whether the Ca2+ signaling pathway is involved in the ability of osteoprotegerin (OPG) to inhibit osteoclast differentiation and maturation. RAW264.7 cells were...
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Hydrogen sulfide protects from acute kidney injury via attenuating inflammation activated by necroptosis in dogs

Wang S, Liu X, Liu Y

Background: The treatment of acute kidney injury (AKI), a common disease in dogs, is limited. Therefore, an effective method to prevent AKI in veterinary clinics is particularly crucial. Objectives: Hydrogen sulfide...
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Muscle fatigue: general understanding and treatment

Wan JJ, Qin Z, Wang PY, Sun Y, Liu X

Muscle fatigue is a common complaint in clinical practice. In humans, muscle fatigue can be defined as exercise-induced decrease in the ability to produce force. Here, to provide a general...
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The Novel Pathogenic Mutation c.849dupT in BRCA2 Contributes to the Nonsense-Mediated mRNA Decay of BRCA2 in Familial Breast Cancer

Li S, Ma J, Hu C, Zhang X, Xiao D, Hao L, Xia W, Yang J, Hu L, Liu X, Dong M, Ma D, Liu R

In this study, we used next-generation sequencing methods to screen 300 individuals for BRCA1 and BRCA2. A novel mutation (c.849dupT) in BRCA2 was identified in a female patient and her...
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Retinoic Acid Promotes Interleukin-4 Plasmid-Dimethylsulfoxide Topical Transdermal Delivery for Treatment of Psoriasis

Chen ZW, Zhang YB, Chen XJ, Liu X, Wang Z, Zhou XK, Qiu J, Zhang NN, Teng X, Mao YQ, Liu CY, Wei YQ, Li J

BACKGROUND: Psoriasis is an autoimmune disease that is caused by a shift in the Th1/Th2 balance toward Th1-dominant immunity. It has been established as an effective treatment to counteract psoriasis...
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Exosomes Derived from Human Amniotic Mesenchymal Stem Cells Facilitate Diabetic Wound Healing by Angiogenesis and Enrich Multiple lncRNAs

Fu S, Zhang H, Li X, Zhang Q, Guo C, Qiu K, Feng J, Liu X, Liu D

BACKGROUND: Diabetic wound healing remains a major challenge due to the impaired functionality of angiogenesis by persistent hyperglycemia. Mesenchymal stem cell exosomes are appropriate candidates for regulating the formation of...
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Phosphodiesterase Type 5 Inhibitors and Risk of Skin Cancers in Men: A Meta-Analysis and Trial Sequential Analysis Involving 7,479,852 Subjects

Lu YP, Fan S, Liang Z, Song Y, Liu K, Zhou K, Wang X, Kang J, Yang Y, Liu X

Purpose: We conducted a systematic review and meta-analysis to quantify the association between phosphodiesterase type 5 inhibitors (PDE5Is) use and skin cancers and we also examined whether down-expression of the...
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Association between COVID-19 and Male Fertility: Systematic Review and Meta-Analysis of Observational Studies

Wang S, Zhang A, Pan Y, Liu L, Niu S, Zhang F, Liu X

Purpose Whether COVID-19 reduces male fertility remains requires further investigation. This meta-analysis and systematic review evaluated the impact of COVID-19 on male fertility. Materials and Methods The literature in PubMed, Embase, MEDLINE, Web...
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Spermatogenesis of Male Patients with Congenital Hypogonadotropic Hypogonadism Receiving Pulsatile Gonadotropin-Releasing Hormone Therapy Versus Gonadotropin Therapy: A Systematic Review and Meta-Analysis

Wei C, Long G, Zhang Y, Wang T, Wang S, Liu J, Ma D, Liu X

Purpose: Pulsatile gonadotropin-releasing hormone (GnRH) therapy and gonadotropin therapy (GT) were widely used for male patients with congenital hypogonadotropic hypogonadism (CHH), but their efficacy was not well compared before. We...
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Gap junction blockage promotes cadmium-induced apoptosis in BRL 3A derived from Buffalo rat liver cells

Hu D, Zou H, Han T, Xie J, Dai N, Zhuo L, Gu J, Bian J, Yuan Y, Liu X, Liu Z

Gap junctions mediate direct communication between cells; however, toxicological cascade triggered by nonessential metals can abrogate cellular signaling mediated by gap junctions. Although cadmium (Cd) is known to induce apoptosis...
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Analysis of Global Sagittal Postural Patterns in Asymptomatic Chinese Adults

Hu P, Yu M, Sun Z, Li W, Jiang L, Wei F, Liu X, Chen Z, Liu Z

STUDY DESIGN: A prospective imaging study. PURPOSE: To characterize the distribution of the global sagittal postural patterns in asymptomatic Chinese adults using Roussouly classification. OVERVIEW OF LITERATURE: The norms of sagittal parameters...
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