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Expression and Significance of MicroRNA155 in Serum of Patients with Cerebral Small Vessel Disease

Guo Y, Li D, Li J, Yang N, Wang D

Objective : This study aimed to investigate the changes and significance of microRNA155 levels in serum of patients with cerebral small vessel disease (CSVD). Methods : Thirty patients with CSVD who...
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Effects of resveratrol on the inflammatory response and renal injury in hyperuricemic rats

Xiao B, Ma W, Zheng Y, Li Z, Li D, Zhang Y, Li Y, Wang D

BACKGROUND/OBJECTIVES: Hyperuricemic nephropathy is a common cause of acute kidney injury. Resveratrol can ameliorate kidney injury, but the explicit mechanism remains unclear. We investigated the effects of resveratrol on the inflammatory...
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Successful Treatment of Biphasic and Peak-dose Dyskinesia With Combined Unilateral Subthalamic Nucleus and Contralateral Globus Pallidus Interna Deep Brain Stimulation

Zeng Z, Lin Z, Huang P, Paerhati H, Zhang C, Li D

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A meta-analysis on advantages of peripheral nerve block post-total knee arthroplasty

You D, Qin L, Li K, Li D, Zhao G, Li L

Background: Postoperative pain management is crucial for patients undergoing total knee arthroplasty (TKA). There have been many recent clinical trials on post-TKA peripheral nerve block; however, they have reported inconsistent...
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Preparation, characterization, and in vivo evaluation of a polymorphic form of valnemulin hydrogen tartrate

Zhu X, Xu S, Lu L, Wang S, Zhao Q, Li D, Li J, Zhao H, Xu B

We prepared a polymorphic form of valnemulin hydrogen tartrate (Form I) to overcome the instability and irritating odor of valnemulin hydrochloride that affect its use in the production and application...
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Quantification of Nerve Viscosity Using Shear Wave Dispersion Imaging in Diabetic Rats: A Novel Technique for Evaluating Diabetic Neuropathy

Liu F, Li D, Xin Y, Liu F, Li W, Zhu J

Objective: Viscoelasticity is an essential feature of nerves, although little is known about their viscous properties. The discovery of shear wave dispersion (SWD) imaging has presented a new approach for...
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Intratracheal Transplantation of Amnion-Derived Mesenchymal Stem Cells Ameliorates Hyperoxia-Induced Neonatal Hyperoxic Lung Injury via Aminoacyl-Peptide Hydrolase

Li Z, Gong X, Li D, Yang X, Shi Q, Ju X

Background and Objectives: Bronchopulmonary dysplasia (BPD) has major effects in premature infants. Although previous literature has indicated that mesenchymal stem cells (MSCs) can alleviate lung pathology in BPD newborns and...
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Comparison between laparoscopic and abdominal radical hysterectomy for stage IB1 and tumor size <2 cm cervical cancer with visible or invisible tumors: a multicentre retrospective study

Li P, Chen L, Ni Y, Liu J, Li D, Guo J, Liu Z, Jin S, Xu Y, Li Z, Wang L, Bin X, Lang J, Liu P, Chen C

Objective: To compare 5-year disease-free survival (DFS) and overall survival (OS) rates of laparoscopic radical hysterectomy (LRH) and abdominal radical hysterectomy (ARH) for stage IB1 and tumor size
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Primary Pericardial Liposarcoma: The Role of Multi-Modality Imaging in the Diagnosis of a Pericardial Mass

Yang F, Wu Q, Yan Y, Zhang Z, Li D

Primary pericardial liposarcomas are extremely rare. We presented a case of a 69-year-old man who presented with exertional dyspnea for more than one week. A pericardial mass was detected by...
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Inhibition of lncRNA KCNQ1OT1 Improves Apoptosis and Chemotherapy Drug Response in Small Cell Lung Cancer by TGF-β1 Mediated Epithelial-to-Mesenchymal Transition

Li D, Tong Q, Lian Y, Chen Z, Zhu Y, Huang W, Wen Y, Wang Q, Liang S, Li M, Zheng J, Liu Z, Liu H, Guo L

Purpose Drug resistance is one of the main causes of chemotherapy failure in patients with small cell lung cancer (SCLC), and extensive biological studies into chemotherapy drug resistance are required....
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Impact of Age on Clinicopathological Features and Survival of Patients with Noncardia Gastric Adenocarcinoma

Bautista M, Jiang SF, Armstrong , Postlethwaite D, Li D

PURPOSE: Gastric cancer often occurs in the elderly but is uncommon in young individuals. Whether young patients have different clinical behaviors and outcomes from those of older patients remain unclear. MATERIALS...
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The influence of the extent of lymph node metastasis on the prognosis for patients with intrahepatic cholangiocarcinoma

Wang J, Shu M, Peng H, Li S, Li D, Shen J, Kuang M, Zhang Y, Chen Z

Purpose: Reports showed that some of intrahepatic cholangiocarcinoma (ICC) patients with lymph node metastasis (LNM) may also gain survival benefit undergone resection. However, the effect of the extent of LNM...
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Involvement of Estrogen Receptor-α in the Activation of Nrf2-Antioxidative Signaling Pathways by Silibinin in Pancreatic β-Cells

Chu C, Gao X, Li X, Zhang X, Ma R, Jia Y, Li D, Wang D, Xu F

Silibinin exhibits antidiabetic potential by preserving the mass and function of pancreatic β-cells through up-regulation of estrogen receptor-α (ERα) expression. However, the underlying protective mechanism of silibinin in pancreatic β-cells...
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Pallidus Stimulation for Chorea-Acanthocytosis: A Systematic Review and Meta-Analysis of Individual Data

He W, Li C, Dong H, Shao L, Yin B, Li D, Ye L, Hu P, Zhang C, Yi W

A significant proportion of patients with chorea-acanthocytosis (ChAc) fail to respond to standard therapies. Recent evidence suggests that globus pallidus internus (GPi) deep brain stimulation (DBS) is a promising treatment...
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Atrial fibrillation in critically ill patients who received prolonged mechanical ventilation: a nationwide inpatient report

Lin Z, Han H, Guo W, Wei X, Guo Z, Zhai S, Li S, Ruan Y, Hu F, Li D, He J

Background/Aims: To evaluate temporal trends of atrial fibrillation (AF) prevalence in critically ill patients who received prolonged mechanical ventilation (MV) in the United States. Methods: We used the 2008 to 2014...
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Urinary Biomarkers for the Noninvasive Detection of Gastric Cancer

Li D, Yan L, Lin F, Yuan X, Yang X, Yang X, Wei L, Yang Y, Lu Y

Gastric cancer (GC) is associated with high morbidity and mortality rates. Thus, early diagnosis is important to improve disease prognosis. Endoscopic assessment represents the most reliable imaging method for GC...
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Formulation and Evaluation of Irinotecan Suppository for Rectal Administration

Feng H, Zhu Y, Li D

  • KMID: 2048335
  • Biomol Ther.
  • 2014 Jan;22(1):78-81.
Irinotecan suppository was prepared using the moulding method with a homogeneous blend. A sensitive and specific fluorescence method was developed and validated for the determination of irinotecan in plasma using...
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A reinforced suture method for stapled gastrointestinal anastomosis to reduce gastrointestinal hemorrhage during Whipple operation in laparoscopy

Zhang L, Jiang N, Jiang L, Liao R, Xiang L, Zhou B, Li D

Purpose: Laparoscopy is being increasingly accepted for pancreaticoduodenectomy. Stapled anastomosis (SA) is used extensively to facilitate laparoscopic pancreaticoduodenectomy (LPD); however, the incidence of anastomotic bleeding after stapled gastrointestinal anastomosis is...
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Alpha-Ketoglutarate: Physiological Functions and Applications

Wu N, Yang M, Gaur U, Xu H, Yao Y, Li D

Alpha-ketoglutarate (AKG) is a key molecule in the Krebs cycle determining the overall rate of the citric acid cycle of the organism. It is a nitrogen scavenger and a source...
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Association of Apolipoprotein E Polymorphisms with White Matter Lesions and Brain Atrophy

Niu Z, Zhang P, Li D, Zhu C, Feng L, Xiong G, Song N, Tang P, Liu F

Objective Apolipoprotein E (ApoE) is mainly synthesized in the liver. So far, it is unknown the relationship among APOE gene polymorphisms and WML, brain atrophy. Therefore, the aim of the...
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