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Genetic characterization of H9N2 avian influenza virus previously unrecognized in Korea

Heo GB, Kye SJ, Sagong M, Lee EK, Lee KN, Lee YN, Choi KS, Lee MH, Lee YJ

In this study, we describe the isolation and characterization of previously unreported Y280-lineage H9N2 viruses from two live bird markets in Korea in June 2020. Genetic analysis revealed that they...
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Novel reassortants of clade 2.3.4.4 H5N6 highly pathogenic avian influenza viruses possessing genetic heterogeneity in South Korea in late 2017

Lee YN, Cheon SH, Kye SJ, Lee EK, Sagong M, Heo GB, Kang YM, Cho HK, Kim YJ, Kang HM, Lee MH, Lee YJ

Novel H5N6 highly pathogenic avian influenza viruses (HPAIVs) were isolated from duck farms and migratory bird habitats in South Korea in November to December 2017. Genetic analysis demonstrated that at...
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Pathogenicity of clade 2.3.4.4 H5N6 highly pathogenic avian influenza virus in three chicken breeds from South Korea in 2016/2017

Park SC, Song BM, Lee YN, Lee EK, Heo GB, Kye SJ, Lee KH, Bae YC, Lee YJ, Kim B

In 2016, novel H5N6 highly pathogenic avian influenza virus emerged in Korea. During the outbreak, the virus caused the largest culling, especially in brown chicken lines. We determined the pathogenicity...
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Enhanced immune response with foot and mouth disease virus VP1 and interleukin-1 fusion genes

Park JH, Kim SJ, Oem JK, Lee KN, Kim YJ, Kye SJ, Park JY, Joo YS

The capsid of the foot and mouth disease (FMD) virus carries the epitopes that are critical for inducing the immune response. In an attempt to enhance the specific immune response,...
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Control of type O foot-and-mouth disease by vaccination in Korea, 2014–2015

Park JH, Tark D, Lee KN, Chun JE, Lee HS, Ko YJ, Kye SJ, Kim YJ, Oem JK, Ryoo S, Lim SB, Lee SY, Choi JH, Ko MK, You SH, Lee MH, Kim B

On December 3, 2014, a type O foot-and-mouth disease (FMD) outbreak began in Korea. Although vaccinations were administered, FMD cases increased steadily for five months, and reached 185 cases by...
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Development of a Lightcycler-based reverse transcription polymerase chain reaction for the detection of foot-and-mouth disease virus

Oem JK, Kye SJ, Lee KN, Kim YJ, Park JY, Park JH, Joo YS, Song HJ

  • KMID: 1091201
  • J Vet Sci.
  • 2005 Sep;6(3):207-212.
One step TaqMan real-time reverse transcription polymerase chain reaction (R/T RT-PCR)using a set of primers/probes was developed for the detection of foot-and-mouth disease (FMD)virus. The gene-specific probes labeled fluorogen for...
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Development of an attenuated vaccine strain from a korean respiratory type infectious bronchitis virus

Choi KS, Jeon WJ, Lee EK, Kye SJ, Park MJ, Kwon JH

  • KMID: 1991799
  • Korean J Vet Res.
  • 2011 Sep;51(3):193-201.
An attenuated vaccine strain AVR1/08 of Korean respiratory type of infectious bronchitis virus (IBV) was developed by 89th passages of IBV D85/06 strain in chicken eggs. The AVR1/08 strain had...
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Preparation and diagnostic utility of a hemagglutination inhibition test antigen derived from the baculovirus-expressed hemagglutinin-neuraminidase protein gene of Newcastle disease virus

Choi KS, Kye SJ, Jeon WJ, Park MJ, Kim S, Seul HJ, Kwon JH

A recombinant hemagglutinin-neuraminidase (rHN) protein from Newcastle disease virus (NDV) with hemagglutination (HA) activity was expressed in Spodoptera frugiperda cells using a baculovirus expression system. The rHN protein extracted from...
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Development of synthetic peptide ELISA based on nonstructural protein 2C of foot and mouth disease virus

Oem JK, Kye SJ, Lee KN, Park JH, Kim YJ, Song HJ, Yeh M

  • KMID: 1090767
  • J Vet Sci.
  • 2005 Dec;6(4):317-325.
It was reported that the sera of convalescent animals contain antibodies to foot and mouth disease (FMD) virus (FMDV) 2C, highly conserved nonstructural protein (NSP), whereas the sera of vaccinated...
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Generation and Biological Characterization of a Neutralization-Resistant Mutant of Newcastle Disease Virus

Park MJ, Kye SJ, Kim JY, Kim S, Seul HJ, Park CK, Choi KS

A neutralization-resistant mutant of Newcastle disease virus (NDV) Kr005 strain belonging to class II genotype VII was generated using a neutralizing monoclonal antibody and its biological effects were assessed. The...
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Biological Property of Recombinant Hemagglutinin-Neuraminidase Protein of Avian Paramyxovirus Type 6 Expressed by Recombinant Baculovirus

Kim JY, Lee HJ, Kye SJ, Kim S, Seul HJ, Kim SE, Lee HS, Jung SC, Choi KS

Hemagglutination inhibition (HI) test employing whole virus antigen is a prescribed serological test for serotyping, diagnosis and surveillance for avian paramyxoviruses (APMVs). For use as alternative to the virus antigen,...
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Identification and antigenic site analysis of foot-and-mouth disease virus from pigs and cattle in Korea

Oem JK, Lee KN, Cho IS, Kye SJ, Park JY, Park JH, Kim YJ, Joo YS, Song HJ

  • KMID: 1114852
  • J Vet Sci.
  • 2005 Jun;6(2):117-124.
From May to June 2002, a total of 16 foot-and mouth disease (FMD) outbreaks due to the serotype O virus, Pan Asia strain, were recorded in Korea. The viruses were...
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