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Legal and Ethical Use of Biospecimens in Research Following Major Revision of the Bioethics and Safety Act

Chang YJ, Kong SY

The recent revision of the Bioethics and Safety Act has created some confusion as to the appropriate use of biospecimens in research. Here, to avoid misunderstandings, we outline the changes...
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Assessment of Effects of Phlebotomy in Patients with Polycythemia Vera and Secondary Polycythemia

Kong JH, Lee SN, Eom HS, Lee H, Han JY, Yoo H, Shim HE, Kong SY

  • KMID: 2299996
  • Korean J Blood Transfus.
  • 2013 Dec;24(3):265-274.
BACKGROUND: Polycythemia vera (PV) is a myeloproliferative neoplasm that can cause complications such as thrombosis and organ damage. To prevent complications of PV, therapy for maintenance of a hematocrit target...
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Recommendation for the Peripheral Blood Cell Morphology Report

Kwon JA, Kim YG, Park G, Kim JM, Cho YU, Huh J, Kong SY, Han JY, Yoon SY

There is considerable heterogeneity in the peripheral blood smear reports across different diagnostic laboratories, despite following the guidelines published by the International Council for Standardization in Haematology (ICSH). As standardization...
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Comparison of Two Apheresis Systems of COBE and Optia for Autologous Peripheral Blood Stem Cell Collection

Lee SN, Sohn JY, Kong JH, Eom HS, Lee H, Kong SY

Peripheral blood stem cell (PBSC) transplantation following myeloablative therapy is a mainstay of treatment for various types of malignancies. This study aimed to evaluate the differences between the Optia MNC...
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A Case of Locally Advanced Breast Cancer Complicated by Pulmonary Tumor Thrombotic Microangiopathy

Kim HJ, Kwak MH, Kong SY, Seong MW, Kang HS, Lee KS, Ro J

  • KMID: 1804887
  • Cancer Res Treat.
  • 2012 Dec;44(4):267-270.
Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare, malignancy-related complication that causes marked pulmonary hypertension, right heart failure, and death. We report on a patient with locally advanced breast cancer...
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1,5-Anhydroglucitol as a Marker of Glycemic Control

Lee SY, Lee SG, Kong SY, Ko SY, Kim JW

  • KMID: 2225931
  • Korean J Clin Pathol.
  • 2000 Apr;20(2):157-162.
BACKGROUND: 1,5-Anhydroglucitol(1,5-AG) has shown to be a better indicator for current status of glycemia than HbA1c or fructosamine. The concentration of 1,5-AG is stable because of large storage pool and...
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Clinical Effects and Safety of Therapeutic Leukapheresis in Hyperleukocytosis

Lee SN, Kong JH, Eom HS, Lee H, Park HJ, Sohn JY, Kong SY

BACKGROUND: Therapeutic leukapheresis is the cytoreduction procedure performed before chemotherapy in patients with hyperleukocytosis for prevention of complication. However, there have been clinical concerns about bleeding tendency due to anticoagulant...
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Expression of Vascular Endothelial Growth Factor in an Animal Model of Avascular Necrosis of the Femoral Head

Yang IH, Kim SH, Kong SY, Joo SY, Yang KH, Hahn SB, Park HW, Kim HW

  • KMID: 1848281
  • J Korean Orthop Res Soc.
  • 2004 Oct;7(2):115-124.
PURPOSE: To evaluate the pathologic changes, apoptosis of chondrocytes, and expression pattern of vascular endothelial growth factor (VEGF) in the growth plate of Spontaneouly Hypertensive Rats (SHR). MATERIALS AND METHODS: Sixty...
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Evaluation of Clinical Parameters and Symptoms in Healthy Donors for Granulocyte Collection

Lee SN, Lee H, Eom HS, Sohn JY, Kong JH, Kong SY

BACKGROUND: Donor granulocyte transfusion has been used as a salvage treatment for neutropenic patients with severe infection who did not respond to antibiotics. Here we investigated hematological parameters of granulocyte...
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Guidelines for Genetic Counseling and Reporting of Cancer Genetic Test Results: Genetic Test for Hereditary Cancer-predisposing Syndrome Using Next-generation Sequencing

Kim DH, Kim N, Kong SY

Genetic counseling and reporting on cancer genetic test results using next-generation sequencing (NGS) are practiced in various ways in different Korean genetic laboratories. Therefore, the Korean Society for Genetic Diagnostics...
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Rapid Sequential Gain of ABL1 Kinase Domain Mutations with a Complex Karyotype in the Progression of Chronic Myelogenous Leukemia

Chung Y, Eom HS, Lee H, Park S, Shim H, Cho EH, Kong SY

No abstract available.
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Evaluation of In Hwa Reagent for the Chemistry Autoanalyzer

Lee SG, Kong SY, Song SM, Lee SY, Kim JW

  • KMID: 2055430
  • J Clin Pathol Qual Control.
  • 2000 Dec;22(2):271-275.
BACKGROUND: Although the autochemistry test plays an important role in the clinical laboratory, most clinical laboratories in the Korea have used the foreign reagent for the autochemistry test. Fortunately many...
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A Case of Childhood Paroxysmal Cold Hemoglobinuria Related with Suspicious Chlamydia Infection

Yoon JH, Cho JS, Park HJ, Shim H, Kong SY, Yoon JY, Park BK

Paroxysmal cold hemoglobinuria (PCH) is a rare diagnosis of acquired hemolytic anemia in children, which is caused by a specific cold antibody named Donath-Landsteiner hemolysin. Although various bacteria or viruses...
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Clinical Features of Li-Fraumeni Syndrome in Korea

Song R, Kong SY, Choi W, Lee EG, Woo J, Han JH, Lee S, Kang HS, Jung SY

Purpose Li-Fraumeni syndrome (LFS) is a hereditary disorder caused by germline mutation in TP53. Owing to the rarity of LFS, data on its clinical features are limited. This study aimed...
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Somatic Mutations from Whole Exome Sequencing Analysis of the Patients with Biliary Tract Cancer

Yoon KA, Woo SM, Kim YH, Kong SY, Han SS, Park SJ, Lee WJ

Biliary tract cancer (BTC) is a rare cancer and is associated with a poor prognosis. To understand the genetic characteristics of BTC, we analyzed whole-exome sequencing data and identified somatic...
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Evaluation of Yeong Dong Reagent for the Automated Chemistry Test

Lee SG, Kong SY, Song SM, Lee SY, Kim JW

  • KMID: 2055431
  • J Clin Pathol Qual Control.
  • 2000 Dec;22(2):277-281.
BACKGROUND: Most clinical laboratories in the Korean have used the imported reagents for the automated chemistry test. But, considering with the cost-effectiveness of clinical laboratory, We should continuously develop and...
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Proteomic Analysis of DJ-1 Expression in the Muscles of Spastic Cerebral Palsy Patients

Kwak YH, Hahn SB, Kong SY, Hong SW, Kim HW

  • KMID: 2199059
  • J Korean Orthop Res Soc.
  • 2008 Oct;11(2):45-55.
PURPOSE: Using proteomic analysis, this study was performed to see the characteristics of proteins expression in the muscles of spastic cerebral palsy patients. MATERIALS AND METHODS: We studied twelve specimens from...
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Comparison of Effectiveness between Blood Bank Automation System and Manual Method for ABO-RhD Blood Typing and Antibody Screening Test in a Single Center

Song YK, An TK, Hwang JY, Shim HE, Lee DH, Kong SY

BACKGROUND: The automation system for blood typing and antibody screening has been developed and is now used widely. In this study, we evaluated the economic effectiveness between automation system QWALYS-3...
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Effects of Changes in Mechanical Loading on Endochondral Bone Formation in Hindlimb-suspended Rats

Park KB, Joo SY, Kong SY, Kang HJ, Park JH, Kim HW

  • KMID: 1589165
  • Korean J Aerosp Environ Med.
  • 2005 Dec;15(3):100-105.
BACKGROUND: To examine the effects of changes in mechanical loading on endochondral bone formation, a simulated rat model of weightlessness was introduced and the changes in the growth plate were...
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Outcomes of Pregnancy after Breast Cancer in Korean Women:A Large Cohort Study

Lee MH, Kim YA, Hong JH, Jung SY, Lee S, Kong SY, Park B, Lee ES

Purpose The purpose of this study was to determine the rate and outcomes of pregnancies subsequent to breast cancer in Korea, and the effect of such pregnancies on the prognosis of women who...
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