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Serial Assays of QuantiFERON-TB Gold In-Tube and QuantiFERON-TB Gold-Plus in Subjects Exposed to Patients with Active Tuberculosis

Moon HW, Yi A, Yoon S, Kim H, Chung HJ, Hur M, Yun YM, Yoo KH

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Effects of the new diagnosis-related group-based payment system and the increased incentive policy rates on the utilization rate of diagnostic laboratory test in Korea

Lee HR, Kim S, Yun YM, Heo JH, Lee KS, Jeong H, Kwon GC, Um TH, Kim H

A new diagnosis-related group (DRG) based payment system has been implemented in most public hospitals in Korea. We investigated the effects of the new DRG system and its incentive policy...
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A Case of Peritonitis and Disseminated Mucormycosis Caused by Mucor circinelloides in a Patient with Nodal Marginal Zone B-cell Lymphoma

Yoon S, Kim H, Moon HW, Huh HJ, Hur M, Yun YM, Lee MH

Mucormycosis is a fungal infection, which is difficult to treat due to its rapid dissemination and low susceptibility to anti-fungal agents. Peritonitis preceded by gastrointestinal mucormycosis is very rare, and...
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Absolute Change in High-Sensitivity Cardiac Troponin I at Three Hours After Presentation is Useful for Diagnosing Acute Myocardial Infarction in the Emergency Department

Kim JW, Kim H, Yun YM, Lee KR, Kim HJ

Background: A rise and/or fall in cardiac troponin value with at least one value above the 99th percentile upper reference limit is essential for acute myocardial infarction (AMI) diagnosis. We...
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Performance Evaluation of the QXDx BCR-ABL %IS Droplet Digital PCR Assay

Chung HJ, Hur M, Yoon S, Hwang K, Lim HS, Kim H, Moon HW, Yun YM

Accurate detection of BCR-ABL fusion transcripts at and below molecular response (MR) 4 (0.01% International Scale [IS]) is required for disease monitoring in patients with chronic myeloid leukemia (CML). We...
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Report of Korean Association of External Quality Assessment Service on the Accuracy-Based Lipid Proficiency Testing (2016–2018)

Kim JH, Cho Y, Lee SG, Yun YM

The accuracy-based lipid (ABL) proficiency testing (PT) program was started in 2016 by the Korean External Quality Assessment Service to minimize the matrix effect. We analyzed 3 years of the...
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Use of Liquid Chromatography-Tandem Mass Spectrometry for Clinical Testing in Korean Laboratories: a Questionnaire Survey

Chae H, Cho SE, Park HD, Chun S, Lee YW, Yun YM, Song SH, Lee SG, Lee K, Song J, Lee SY, On behalf of the Clinical Mass Spectrometry Research Committee of Korean Society of Clinical Chemistry

BACKGROUND: The use of liquid chromatography-tandem mass spectrometry (LC-MS/MS) has substantially increased in clinical laboratories worldwide. To assess the status of clinical LC-MS/MS testing in Korean laboratories, a questionnaire survey...
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A Questionnaire Survey on General Status and Opinions about Clinical Mass Spectrometric Analysis in Korea (2018)

Cho SE, Chae H, Park HD, Chun S, Lee YW, Yun YM, Song SH, Lee SG, Lee K, Song J, Lee SY, On behalf of the Clinical Mass Spectrometry Research Committee of Korean Society of Clinical Chemistry

The Clinical Mass Spectrometry Research Committee (CMSRC), in affiliation with the Korean Society of Clinical Chemistry (KSCC), conducted a questionnaire survey on opinions about the general status of clinical mass...
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First Case in Korea of Group B Streptococcus With Reduced Penicillin Susceptibility Harboring Amino Acid Substitutions in Penicillin-Binding Protein 2X

Yi A, Kim CK, Kimura K, Arakawa Y, Hur M, Yun YM, Moon HW

No abstract available.
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Two-photon intravital imaging of leukocyte migration during inflammation in the respiratory system

Kim YM, Jeong S, Choe YH, Hyun YM

Two-photon intravital imaging is a powerful method by which researchers are able to directly observe biological phenomena in live organisms. Researchers in various biomedical research fields have applied two-photon imaging...
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Accuracy-Based Proficiency Testing of Creatinine Measurement: 7 Years' Experience in Korea

Jeong TD, Lee HA, Lee K, Yun YM

BACKGROUND: Standardization of creatinine assay is consistently performed and much effort has been put into improving the accuracy of the results. We aimed to analyze the results of accuracy-based proficiency...
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Characteristics of Helicobacter pylori-seropositive subjects according to the stool antigen test findings: a prospective study

Moon HW, Lee SY, Hur M, Yun YM

BACKGROUND/AIMS: In countries with a higher risk of gastric atrophic gastritis, noninvasive tests are helpful for a more reliable diagnosis of Helicobacter pylori infection. The aim of this study was...
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Usefulness of Enhanced Liver Fibrosis, Glycosylation Isomer of Mac-2 Binding Protein, Galectin-3, and Soluble Suppression of Tumorigenicity 2 for Assessing Liver Fibrosis in Chronic Liver Diseases

Moon HW, Park M, Hur M, Kim H, Choe WH, Yun YM

BACKGROUND: Liver biopsies have been partially replaced by noninvasive methods for assessing liver fibrosis. We explored the usefulness of four novel biomarkers, enhanced liver fibrosis (ELF), glycosylation isomer of Mac-2...
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Performance Evaluation of the JEOL BioMajesty JCA-BM6010/C Automated Clinical Chemistry Analyzer

Kim HN, Ji M, Moon HW, Hur M, Yun YM

BACKGROUND: JEOL BioMajesty JCA-BM6010/C (JCA-BM6010/C, JEOL Ltd., Japan) is a recently developed ultra-compact automated clinical chemistry analyzer with a throughput of 1,200 tests per hour. Here, we present the first...
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Clinical Usefulness of Combined Cardiac Marker Testing with a Point-of-Care Device at the Emergency Department

Ji M, Moon HW, Park S, Hur M, Yun YM

BACKGROUND: B-type natriuretic peptide (BNP) levels are elevated in various conditions unrelated to heart failure, such as acute coronary syndrome, and cardiac troponin (cTn) levels may also be elevated in...
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Annual Report on the External Quality Assessment Scheme for Routine Clinical Chemistry in Korea (2016)

Lee YW, Jeon BR, Kim JG, Jun SH, Yun YM, Chun S, Song J, Min WK, Routine Clinical Chemistry Program, Korean Association of External Quality Assessment Service

In 2016, the clinical chemistry proficiency-testing program consisted of 21 programs, including the general chemistry program of the Korean Association of External Quality Assessment Service. The general chemistry program consisted...
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Clinical Pharmacogenetic Testing and Application: Laboratory Medicine Clinical Practice Guidelines

Kim S, Yun YM, Chae HJ, Cho HJ, Ji M, Kim IS, Wee KA, Lee W, Song SH, Woo HI, Lee SY, Chun S

Pharmacogenetic testing for clinical applications is steadily increasing. Correct and adequate use of pharmacogenetic tests is important to reduce unnecessary medical costs and adverse patient outcomes. This document contains recommended...
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Automated Nucleic Acid Extraction Systems for Detecting Cytomegalovirus and Epstein-Barr Virus Using Real-Time PCR: A Comparison Study Between the QIAsymphony RGQ and QIAcube Systems

Kim H, Hur M, Kim JY, Moon HW, Yun YM, Cho HC

BACKGROUND: Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) are increasingly important in immunocompromised patients. Nucleic acid extraction methods could affect the results of viral nucleic acid amplification tests. We compared two...
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Establishing Reference Intervals for Soluble ST2 Assay in a Korean Population

Park M, Ji M, Kim H, Moon HW, Hur M, Yun YM

BACKGROUND: Soluble ST2 (sST2) has emerged as a biomarker of heart failure. Previous studies indicated 35 ng/mL of sST2 as the clinically prognostic cut-off value. This study aims to establish...
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Clinical Utility of Measurement of Vitamin D-Binding Protein and Calculation of Bioavailable Vitamin D in Assessment of Vitamin D Status

Kim HJ, Ji M, Song J, Moon HW, Hur M, Yun YM

BACKGROUND: The associations of vitamin D deficiency with various clinical conditions highlighted the importance of vitamin D testing. Currently, clinicians measure only the total 25-hydroxyvitamin D [25(OH)D] concentration, regardless of...
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