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The Effect of the Vitamin Protocol for Treating Sepsis or Septic Shock in Pediatric Intensive Care Unit

Ko HJ, Jung MJ, Kim JS, Son ES, Yu YM

Background: Recently, a study comprising adult patients with sepsis admitted in the intensive care unit (ICU) was conducted. The patients were treated with high doses of intravenous ascorbic acid, thiamine,...
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Study on the Mitochondrial Dysfunction by p53 Regulation in Ceramide-induced Neuronal Cell Death

Lee D, Lee H, Noh Y, Yun J, Han I, Chung Y, Kim K, Kim S, Lee W

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Phagocytic osteoclasts in the alveolar bone of diabetic rats with periodontitis

Bak EJ, Kim AR, Kim JH, Yoo YJ

Periodontitis is a bacteria-induced inflammatory disease associated with alveolar bone loss. Osteoclast is a macrophage-lineage cell that exhibits phagocytic activity; however, osteoclast phagocytic activity has not been demonstrated under pathological...
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The effect of general health status, oral health behavior and status on quality of life in Korea adults

Jeong HJ, Kim YH, Yun JW, Oh SH, Yoon HS, Lee MK, Lee JH

Objectives: The purpose of this study was to analyze the relations between general health status, oral health behavior, oral health status, and quality of life, as well as the mediating...
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Caries activity test by realtime PCR method and bacterial cultural method

Yun JH, Park JH, Cho JW, Kim SW

Objectives: This study aimed to compare the results of conventional methodology and real-time polymerase chain reaction (PCR) for acid-producing bacteria and identify the appropriate method for caries activity testing. Methods: Oral...
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Methamphetamine-Induced Neuronal Damage: Neurotoxicity and Neuroinflammation

Kim B, Yun J, Park B

Methamphetamine (METH) is a highly addictive psychostimulant and one of the most widely abused drugs worldwide. The continuous use of METH eventually leads to drug addiction and causes serious health...
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Beneficial Effect of Chloroquine and Amodiaquine on Type 1 Diabetic Tubulopathy by Attenuating Mitochondrial Nox4 and Endoplasmic Reticulum Stress

Kang JM, Lee HS, Kim J, Yang DH, Jeong HY, Lee YH, Kim DJ, Park SH, Sung M, Kim J, An HJ, Lee SH, Lee SY

Background: Oxidative stress induced by chronic hyperglycemia is recognized as a significant mechanistic contributor to the development of diabetic kidney disease (DKD). Nonphagocytic nicotinamide adenine dinucleotide phosphate oxidase 4 (Nox4) is...
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Activation of AMPK by Telmisartan Decreases Basal and PDGF-stimulated VSMC Proliferation via Inhibiting the mTOR/p70S6K Signaling Axis

Hwang YJ, Park JH, Cho DH

Background: Telmisartan, an angiotensin II type 1 receptor blocker (ARB), is widely used to treat hypertension by blocking the renin-angiotensin-aldosterone system. Although abnormal proliferation of vascular smooth muscle cells (VSMCs)...
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Sex-specific relationship between vascular calcification and incident fracture in patients with end-stage renal disease

Nam YJ, Hwang SY, Kim DW, Kim D, Shin SJ, Yoon HE

Background: Vascular calcification (VC) is a major component of mineral bone disorders in patients with end- stage renal disease (ESRD). Bone metabolism is affected by various factors, including sex hormones. This...
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Percutaneous Transgastric Stent Placement for Malignant Gastroduodenal Obstruction

Cho B, Jung GS, Yun JH

Purpose: To evaluate the technical feasibility and clinical efficacy of percutaneous transgastric stent placement after the failure of treatment attempt with the transoral approach in malignant gastroduodenal obstruction patients. Materials and...
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vidence-Based Nursing Practice Guideline: Ostomy Care

Lee YJ, Park HS, Kim MK, Seo HW, Lee MJ, Won EA, Jo GN

Purpose: The aim of this study was to develop an evidence-based guideline for stoma management providing institutional policy, assessment, complications and follow-up care. Methods: The guideline adaptation manual consisting of...
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A Validation Study of the Inbrain CST: a Tablet Computer-based Cognitive Screening Test for Elderly People with Cognitive Impairment

Chin J, Kim DE, Lee H, Yun J, Lee BH, Park J, Yeom J, Shin DS, Na DL

Background: Computerized versions of cognitive screening test could have advantages over pencil-and-paper versions by eliminating rater-dependent factors and saving the time required to score the tests and report the results....
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Korean Medication Algorithm for Schizophrenia 2019, Second Revision: Treatment of Psychotic Symptoms

Lee JS, Yun JY, Kang SH, Lee SJ, Choi JH, Nam B, Lee SH, Chung YC, Kim CH

Objective: In 2001, the Korean College of Neuropsychopharmacology and the Korean Society for Schizophrenia Research developed the Korean Medication Algorithm Project for Schizophrenia (KMAP-SPR 2001, revised 2006) through a consensus...
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A Case of Simultaneous Active Transcutaneous Bone Conduction Implantation (BonebridgeTM) Performed with Subtotal Petrosectomy

Han JS, Park JM, Kang YJ, Park SN

Subtotal petrosectomy (STP) is an effective treatment modality for recurrent suppurative otitis media (CSOM) and cochlear implant (CI) may be combined for auditory rehabilitation. An active transcutaneous bone conduction implantation...
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Identification of Fungal Species and Detection of Azole-Resistance Mutations in the Aspergillus fumigatus cyp51A Gene at a South Korean Hospital

Jung IY, Lee YJ, Shim HS, Cho YS, Sohn YJ, Hyun JH, Baek YJ, Kim MH, Kim JH, Ahn JY, Jeong SJ, Ku NS, Park YS, Yeom JS, Kim YK, Kim HY, Choi JY

Purpose: With changing fungal epidemiology and azole resistance in Aspergillus species, identifying fungal species and susceptibility patterns is crucial to the management of aspergillosis and mucormycosis. The objectives of this...
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Inhibition of Ceramide Accumulation in Podocytes by Myriocin Prevents Diabetic Nephropathy

Woo CY, Baek JY, Kim AR, Hong CH, Yoon JE, Kim HS, Yoo HJ, Park TS, Kc R, Lee KU, Koh EH

Background: Ceramides are associated with metabolic complications including diabetic nephropathy in patients with diabetes. Recent studies have reported that podocytes play a pivotal role in the progression of diabetic nephropathy. Also,...
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Autoimmune encephalitis and epilepsy: evolving definition and clinical spectrum

Seo JH, Lee YJ, Lee KH, Gireesh E, Skinner H, Westerveld M

Advances in autoimmune encephalitis studies in the past 10 years have led to the identification of new syndromes and biomarkers that have transformed the diagnostic approach to the disorder. The...
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Lethal Hemomediastinum due to Spontaneous Rupture of an Aberrant Bronchial Artery in a Patient with Neurofibromatosis Type 1: Successful Treatment with Embolization

Im YJ, Choi MJ, Kim BM

Spontaneous bleeding due to vascular involvement of neurofibromatosis type 1 is rare but potentially fatal. Herein, we report a case of a lethal spontaneous hemomediastinum in a patient with neurofibromatosis...
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A New Active Locomotion Capsule Endoscopy under Magnetic Control and Automated Reading Program

Oh DJ, Kim KS, Lim YJ

Capsule endoscopy (CE) is the first-line diagnostic modality for detecting small bowel lesions. CE is non-invasive and does not require sedation, but its movements cannot be controlled, it requires a...
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Pancreatic Hemangioma Suspected of Neuroendocrine Tumor

Jeong MA, Lee JK, Nam JH, Jang DK, Lim YJ, Lee JJ, Kim EJ

Adult pancreatic hemangioma is an extremely rare disease, with only 22 cases reported since 1939. Pancreatic hemangioma has no specific symptoms, diagnostic imaging, or laboratory findings, making it difficult to...
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