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Vascularized Organoids: A More Complete Model

Yu J

As an emerging research model in vitro, organoids have achieved major progress in recapitulating morphological aspects of organs and personalized precision therapy. Various organoids have been currently constructed in vitro...
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Predictive Role of Lung Injury Prediction Score in the Development of Acute Respiratory Distress Syndrome in Korea

Kim BK, Kim S, Kim CY, Kim YJ, Lee SH, Cha JH, Kim JH

Purpose: Early recognition and therapeutic intervention are important in patients at high risk of acute respiratory distress syndrome (ARDS). The lung injury prediction score (LIPS) has been used to predict...
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Organoids: A New Model for SARS-CoV-2 Translational Research

Yu J

The 2019-novel coronavirus (SARS-CoV-2) pneumonia epidemic is a thorny public health problem faced by health officials and a major cause of concern for health professionals. However, the currently used immortalized...
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Comparison of Clinical Outcomes of Borderline Resectable Pancreatic Cancer According to the Neoadjuvant Chemo-Regimens: Gemcitabine versus FOLFIRINOX

Choi YJ, Byun Y, Kang JS, Kim HS, Han Y, Kim H, Kwon W, Oh DY, Paik WH, Lee SH, Ryu JK, Kim YT, Lee K, Kim H, Chie EK, Jang JY

Background/Aims: Although many studies have reported the promising effect of neoadjuvant treatment for borderline resectable pancreatic cancer (BRPC) to increase resectability, only a few studies have recommended the use of...
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Incidence of adverse drug reaction among 6 iodinated contrast media

Koh E, Kim YJ, Kang N, Jin SR, Lee JY, Eo H, Choi DC, Lee BJ

Purpose: Contrast media is one of the most common cause of adverse drug reaction (ADR) in adult. However, there was little data reported about differences in ADR ratio and severity...
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Lifestyle, Health Status and Socioeconomic Factors Associated with Depressive Symptoms in Korean Young Adults: Korean National Health and Nutrition Examination Survey 2017

Chung YJ, Jung HH, Jung C, Lim HS, Kim SC

Background: In recent years, the number of suicides in young adults has increased rapidly, leading to a major social problem. According to several reports, suicide is closely related to depressive...
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Impact of the COVID-19 Outbreak on Emergency Care Utilization in Patients with Acute Myocardial Infarction: a Nationwide Population-based Study

Sung HK, Paik JH, Lee YJ, Kang S

Background: The coronavirus disease 2019 (COVID-19) pandemic has impacted various aspects of daily living and has influenced the life of every individual in a unique way. Acute myocardial infarction (AMI) is...
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Association between BDNF Polymorphism and Depressive Symptoms in Patients Newly Diagnosed with Type 2 Diabetes Mellitus

Ryu JS, Lee YM, Kim YS, Kang S, Park JS, Ahn CW, Nam JS, Seok JH

Purpose: Little is known about the relationship between brain-derived neurotrophic factor (BDNF) gene polymorphisms and psychiatric symptoms in diabetes patients. We investigated the effects of BDNF Val/66/Met polymorphism, glucose status,...
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Dysregulated Free Fatty Acid Receptor 2 Exacerbates Colonic Adenoma Formation in ApcMin/+ Mice: Relation to Metabolism and Gut Microbiota Composition

Huang YW, Lin CW, Pan P, Echeveste CE, Dong A, Oshima K, Yearsley M, Yu J, Wang LS

Free fatty acid receptor 2 (FFAR2) has been reported as a tumor suppressor in colon cancer development. The current study investigated the effects of FFAR2 signaling on energy metabolism and...
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Genomic mutation profiling using liquid biopsy in Korean patients with prostate cancer: Circulating tumor DNA mutation predicts the development of castration resistance

Yu J, Cho E, Choi J, Lim JE, Lee J, Kang M, Sung HH, Jeong BC, Seo SI, Jeon SS, Lee HM, Jeon HG

Purpose: To investigate germline and somatic mutation profiles in Korean patients with prostate cancer using liquid biopsy and solid tissue testing and to evaluate the prognostic value of circulating tumor...
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Prognostic Factors for Patients with Borderline Resectable or Locally Advanced Pancreatic Cancer Receiving Neoadjuvant FOLFIRINOX

Choi YH, Lee SH, You MS, Shin BS, Paik WH, Ryu JK, Kim YT, Kwon W, Jang JY, Kim SW

Background/Aims: There has been growing evidence on the utility of neoadjuvant FOLFIRINOX in borderline resectable (BR) or locally advanced (LA) pancreatic cancer. However, factors predicting survival in these patients remain...
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Clinical and Histopathologic Study of Lichen Nitidus-Like Papular Eruptions; Eruptive Idiopathic Papulosis

Jeon YJ, Koo DW, Lee JS

  • KMID: 2513440
  • Korean J Dermatol.
  • 2021 Feb;59(2):125-131.
Background: A large number of patients present with multiple papular skin lesions at the outpatient department of dermatology. In practice, however, the clinical presentation and skin histology has often been...
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Association between Urinary Cotinine-Verified Smoking Status and High-Sensitivity C-Reactive Protein in Korean Adults: Based on Korea National Health and Nutrition Examination Survey 2016–2018

Kim Yj, Kim SY, Hwang Ih, Paek YJ

Background: C-reactive protein (CRP) can be used to assess the risk of cardiovascular disease in adults. Previous studies have reported a relationship between self-reported smoking status and high-sensitivity CRP (hs-CRP)...
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Symptom Experience and Related Predictors in Liver Transplantation Recipients

Chen X, Zhang Y, Yu J

Purpose Symptom experience after liver transplantation (LT) provides healthcare professionals with important information about the benefits and limitations of LT from patients’ perspective. This study aims to explore the multidimensional symptom...
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Cutaneous Photosensitivity Possibly Induced by Paclitaxel and Trastuzumab

Lee HY, Jeon YJ, Koo DW, Lee JS

  • KMID: 2512424
  • Korean J Dermatol.
  • 2021 Jan;59(1):77-79.
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The Psychological Burden of COVID-19 Stigma: Evaluation of the Mental Health of Isolated Mild Condition COVID-19 Patients

Kang E, Lee SY, Kim MS, Jung H, Kim KH, Kim KN, Park HY, Lee YJ, Cho B, Sohn JH

Background: The objective of this article is to assess the mental health issues of the mild condition coronavirus disease 2019 (COVID-19) patients admitted to a community treatment center (CTC) in...
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Clinical and Neuroimaging Features in Charcot-Marie-Tooth Patients with GDAP1 Mutations

Kim HS, Kim HJ, Nam SH, Kim SB, Choi YJ, Lee KS, Chung KW, Yoon YC, Choi BO

Background and Purpose Mutations in the ganglioside-induced differentiation-associated protein 1 gene (GDAP1) are known to cause Charcot-Marie-Tooth disease (CMT). These mutations are very rare in most countries, but not in...
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Transcriptional profiling of mouse cavernous pericytes under high-glucose conditions: Implications for diabetic angiopathy

Yin GN, Wu J, Cui Y, Lin C, Shi L, Gao ZL, Suh JK, Ryu JK, Jin HR

Purpose: Penile erection requires integrative interactions between vascular endothelial cells, pericytes, smooth muscle cells, and autonomic nerves. Furthermore, the importance of the role played by pericytes in the pathogenesis of...
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Gene expression profiling of mouse cavernous endothelial cells for diagnostic targets in diabetes-induced erectile dysfunction

Yin GN, Ock J, Choi MJ, Limanjaya A, Ghatak K, Song KM, Kwon MH, Suh JK, Ryu JK

Purpose: To investigate potential target genes associated with the diabetic condition in mouse cavernous endothelial cells (MCECs) for the treatment of diabetes-induced erectile dysfunction (ED). Materials and Methods: Mouse cavernous tissue...
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Three-Dimensional Reconstruction of Neurovascular Network in Whole Mount Preparations and ThickCut Transverse Sections of Mouse Urinary Bladder

Nguyen NM, Song KM, Choi MJ, Ghatak K, Limanjaya A, Kwon MH, Chung DY, Ock J, Yin GN, Park CS, Suh JK, Ryu JK

Purpose: Proper functional and structural integrity of nervous and vascular system in urinary bladder plays an important role in normal bladder function and the disruption of these structures is known...
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