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Gastroprotective effect of cirsilineol against hydrochloric acid/ ethanol-induced gastric ulcer in rats

Gong G,  Zhao R, Zhu Y, Yu J, Wei B, Xu Y, Cui Z, Liang G

This study was designed to evaluate the gastroprotective activity of cirsilineol in hydrochloric acid (HCl)/ethanol-induced gastric ulcer model. Cirsilineol was administered at the doses of 20 and 40 mg/kg in HCl/ethanol-induced...
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Effect of Poloxamer-Based ThermoSensitive Sol-Gel Agent on Upper Limb Dysfunction after Axillary Lymph Node Dissection: A Double-Blind Randomized Clinical Trial

Choi HJ, Ryu JM, Chae BJ, Kim EK, Min JW, Shin HJ, Nam SJ, Yu J, Lee JE, Lee SK, Kim SW

Purpose: Restricted shoulder motion is a major morbidity associated with a lower quality of life and disability after axillary lymph node dissection (ALND) in patients with breast cancer. This study sought...
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Changes in Korean National Healthcare Insurance Policy and Breast Cancer Surgery Trend in Korea

Rayzah M, Ryu JM, Lee JH, Nam SJ, Kim SW, Lee SK, Yu J, Lee KT, Bang SI, Mun GH, Pyon JK, Jeon BJ, Lee JE

Background: Since April 2015, the Korean National Health Insurance (NHI) has reimbursed breast cancer patients, approximately 50% of the cost of the breast reconstruction (BR) procedure. We aimed to investigate...
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Clusters of Toxoplasmosis in Ganghwa-gun, Cheorwon-gun, and Goseong-gun, Korea

Yu J, Kim W, Chang YK, Kim TS, Hong SJ, Ahn HJ, Nam HW, Kim D

We find out the clusters with high toxoplasmosis risk to discuss the geographical pattern in Gyodong-myeon and Samsan-myeon of Ganghwa-gun, Cheorwon-gun, and Goseong-gun, Korea. Seroepidemiological data of toxoplasmosis surveyed using...
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Vascularized Organoids: A More Complete Model

Yu J

As an emerging research model in vitro, organoids have achieved major progress in recapitulating morphological aspects of organs and personalized precision therapy. Various organoids have been currently constructed in vitro...
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Clinical Outcomes between Amniotic Membrane Transplantation and Conjunctival Autograft Using Fibrin Glue for Pterygium Surgery

Lee SJ, Yang HS, Choi JH, Yu J, Chung YR

Purpose: We compared clinical outcomes including recurrence rate between amniotic membrane transplantation (AMT) and conjunctival autograft using fibrin glue and minimal conjunctival sutures for pterygium surgery. Methods: We retrospectively analyzed 217...
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Valsartan Dosage on Ventriculo-Vascular Coupling Index Dose-Dependency in Heart Failure Patients

Ahn KJ, Yu J, Jang AY, Kim DH, Kwan J, Chung WJ

Purpose: Heart failure (HF) poses significant morbidity and mortality. Recently, the ventriculo-vascular coupling index (VVI) was introduced as an independent prognostic factor reflective of the overall cardiovascular performance index in...
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Organoids: A New Model for SARS-CoV-2 Translational Research

Yu J

The 2019-novel coronavirus (SARS-CoV-2) pneumonia epidemic is a thorny public health problem faced by health officials and a major cause of concern for health professionals. However, the currently used immortalized...
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Thyroid imaging study in children with suspected thyroid dysgenesis

Chun S, Lee YS, Yu J

Purpose: Thyroid dysgenesis is one of the most common causes of permanent congenital hypothyroidism. Thyroid ultrasonography or scan is used to detect thyroid dysgenesis. We analyzed the sensitivity and specificity...
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Dysregulated Free Fatty Acid Receptor 2 Exacerbates Colonic Adenoma Formation in ApcMin/+ Mice: Relation to Metabolism and Gut Microbiota Composition

Huang YW, Lin CW, Pan P, Echeveste CE, Dong A, Oshima K, Yearsley M, Yu J, Wang LS

Free fatty acid receptor 2 (FFAR2) has been reported as a tumor suppressor in colon cancer development. The current study investigated the effects of FFAR2 signaling on energy metabolism and...
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Genomic mutation profiling using liquid biopsy in Korean patients with prostate cancer: Circulating tumor DNA mutation predicts the development of castration resistance

Yu J, Cho E, Choi J, Lim JE, Lee J, Kang M, Sung HH, Jeong BC, Seo SI, Jeon SS, Lee HM, Jeon HG

Purpose: To investigate germline and somatic mutation profiles in Korean patients with prostate cancer using liquid biopsy and solid tissue testing and to evaluate the prognostic value of circulating tumor...
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Relation Between Tumor Size and Lymph Node Metastasis According to Subtypes of Breast Cancer

Min SK, Lee SK, Woo J, Jung SM, Ryu JM, Yu J, Lee JE, Kim SW, Chae BJ, Nam SJ

Purpose: Tumor size and lymph node metastasis are important factors that contribute to the progression of breast cancer. We aimed to analyze the relationship between tumor size and lymph node...
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Symptom Experience and Related Predictors in Liver Transplantation Recipients

Chen X, Zhang Y, Yu J

Purpose Symptom experience after liver transplantation (LT) provides healthcare professionals with important information about the benefits and limitations of LT from patients’ perspective. This study aims to explore the multidimensional symptom...
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Effect of Leukocyte-Platelet Rich Fibrin (L-PRF) on Tissue Regeneration and Proliferation of Human Gingival Fibroblast Cells Cultured Using a Modified Method

Mudalal M, Wang Z, Mustafa S, Liu Y, Wang Y, Yu J, Wang S, Sun X, Zhou Y

Background: An in vitro study on rapid culturing method of human gingival fibroblast cells (HGFCs) was established to investigate the potential use of the leukocyte-platelet rich fibrin (L-PRF) in tissue engineering...
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Effect of Conditioned Medium from Human Umbilical Cord-Derived Mesenchymal Stromal Cells on Rejuvenation of Nucleus Pulposus Derived Stem/Progenitor Cells from Degenerated Intervertebral Disc

Zeng X, Lin J, Wu H, Yu J, Tu M, Cheang LH, Zhang J

Background and Objectives: Mesenchymal stromal cells (MSCs)-based treatment for degeneration of intervertebral disc (IVD) has been proposed recently. We here addressed whether MSC secreted factors can rejuvenate nucleus pulposus- derived...
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Prognostic Factors for Premenopausal Women with Distant Metastatic Breast Cancer

Seung J, Ryu JM, Nam SJ, Lee JE, Yu J, Lee SK, Chae BJ, Kim SW

Purpose: Several studies have reported that the survival after distant metastasis in younger patients with breast cancer was similar to that in elderly patients. Moreover, few studies have observed better...
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Anti-colonic Inflammation by Black Raspberries through Regulating Toll-like Receptor-4 Signaling in Interlukin-10 Knockout Mice

Huang YW, Echeveste CE, Oshima K, Zhang J, Yearsley M, Yu J, Wang LS

Ulcerative colitis (UC) is a chronic inflammatory disease of the colon, with a steadily rising prevalence in Western and newly industrialized countries. UC patients have a cancer incidence as high...
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Application of a Documentary about High-risk Newborns in Nursing Education: An Exploratory Study

Kang HJ, Yu J

Purpose: The purpose of this study was to explore nursing students' recognition and understanding of the clinical environment of high-risk neonatal nursing care after watching a documentary about the neonatal...
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Combined Transarterial Chemoembolization and External Beam Radiotherapy in a Patient with Recurrent Huge Hepatocellular Carcinoma after Hepatic Resection

Yu J, Jung J, Yoon SM

The optimal treatment strategy for unresectable huge hepatocellular carcinoma (HCC) is yet to be established. Non-surgical monotherapy demonstrated insufficient oncologic outcomes in previously reported studies. To improve the clinical outcomes...
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The Time of Return to Play after Surgery for Chronic Lateral Ankle Instability in Athletes: A Systematic Review

Kim J, Yu J, Chae H

Purpose: The study aimed to assess the average time to return to play following surgery for chronic lateral ankle instability in athletes. Methods: A literature search was conducted (1976 to 2019)...
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