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Selective inhibition of V600E-mutant BRAF gene induces apoptosis in thyroid carcinoma cell lines

Park KS, Saindane M, Yang EY, Jin T, Rallabandi HR, Heil A, Nam SE, Yoo YB, Yang JH, Kim JB, Park SY, Park WS, Youn YK

Purpose: Papillary thyroid cancer (PTC) has a high incidence of BRAF V600E mutation. The purpose of this study was to evaluate the potential relationship between thyroiditis and BRAF ...
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Comparative study of bilateral axillo-breast approach endoscopic and robotic thyroidectomy: propensity score matching analysis of large multi-institutional data

Choi JY, Bae IE, Kim HS, Yoon SG, Yi JW, Yu HW, Kim Sj, Chai YJ, Lee KE, Youn YK

Purpose: The aim of this study was to compare the large multi-institutional data of surgical outcomes of bilateral axillo-breast approach (BABA) robotic (RT) and endoscopic thyroidectomy (ET) and to evaluate...
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Role of charcoal tattooing in localization of recurred papillary thyroid carcinoma: initial experiences

Kwon H, Tae SY, Kim SJ, Jung KC, Kim JH, Lee KE, Youn YK

PURPOSE: Surgical excision is the definitive treatment for localized recurrence of papillary thyroid carcinoma. Reoperation for recurrence, however, is challenging and associated with increased operative times and complication rates. For...
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Intraoperative neuromonitoring of the external branch of the superior laryngeal nerve during robotic thyroid surgery: a preliminary prospective study

Kim SJ, Lee KE, Oh BM, Oh EM, Bae DS, Choi JY, Myong JP, Youn YK

PURPOSE: The aim of this study was to evaluate the feasibility of monitoring external branch of the superior laryngeal nerve (EBSLN) during robotic thyroid surgery. METHODS: A total of 10 patients...
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Can Robotic Thyroidectomy Be Performed Safely in Thyroid Carcinoma Patients?

Chai YJ, Lee KE, Youn YK

Since the adoption of the Da Vinci robotic system for remote access thyroid surgery, robotic thyroidectomy (RT) has become a popular surgical option for patients who want to avoid neck...
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Localization of Parathyroid Adenoma and Minimally Invasive Parathyroidectomy: A Review

Suh YJ, Kim SJ, Lee KE, Youn YK

More than 80% of cases of patients with sporadic primary hyperparathyroidism are caused by a single parathyroid adenoma. Therefore, traditional bilateral neck exploration has been replaced by minimally invasive parathyroidectomy...
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Characteristics of Hypoparathyroidism after Total Thyroidectomy with or without Hashimoto Thyroiditis

Lee D, Kim E, Chung I, Kim S, Ahn E, Park JM, Park S, Youn YK

PURPOSE: The characteristics of hypoparathyroidism in patients with Hashimoto thyroiditis (HT) after total thyroidectomy are not well established. The aim of this study was to investigate the relationship between hypoparathyroidism...
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Gene Methylation Associated with Differentiated Thyroid Cancer

Tae SY, Chi HK, Kim SJ, Lee KE, Youn YK

Epigenetic alteration changes expression of many genes, such as tumor suppressor gene and molecular specific gene, without change in DNA sequence. Cancers, including thyroid cancer, often exhibit an aberrant methylation...
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Role of adjuvant postoperative external beam radiotherapy for well differentiated thyroid cancer

Kwon J, Wu HG, Youn YK, Lee KE, Kim KH, Park DJ

PURPOSE: To analyze the outcome of adjuvant postoperative external beam radiotherapy (EBRT) in well-differentiated thyroid cancer (WDTC). MATERIALS AND METHODS: We identified 84 patients treated with EBRT for WDTC from February...
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Antiadhesive effect and safety of oxidized regenerated cellulose after thyroidectomy: a prospective, randomized controlled study

Park KS, Lee KE, Ku DH, Kim SJ, Park WS, Kim HY, Kwon MR, Youn YK

PURPOSE: To evaluate the antiadhesive effects and safety of an oxidized regenerated cellulose (Interceed) after thyroidectomy. METHODS: Seventy-six thyroidectomized patients were prospectively randomized into two groups with regard to the use...
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Antiadhesive effect and safety of sodium hyaluronate-carboxymethyl cellulose membrane in thyroid surgery

Bae DS, Woo JW, Paek SH, Kwon H, Chai YJ, Kim SJ, Choi JY, Lee KE, Youn YK

  • KMID: 2324872
  • J Korean Surg Soc.
  • 2013 Nov;85(5):199-204.
PURPOSE: A number of researchers have suggested the use of sodium hyaluronate carboxymethyl cellulose (HA-CMC) membrane for preventing postoperative adhesion. This study evaluated the antiadhesive effect and safety of HA-CMC...
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Analysis of patients with anaplastic thyroid cancer expected to have curative surgery

Oh EM, Lee KE, Kwon H, Kim EY, Bae DS, Youn YK

PURPOSE: Anaplastic thyroid cancer (ATC) is rare and has a poor prognosis. The aim of this study was to analyze the clinicopathologic characteristics of patients diagnosed with ATC expected to...
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Regionalization strategy of the emergency medical service system

Youn YK

A regionalization strategy is a model for improving the performance of the emergency medical service (EMS) system. The regionalization strategy has goals to provide appropriate, timely, effective, and efficient EMS...
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An exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in Korea

Yi JW, Oh EM, Lee KE, Choi JY, Koo DH, Kim KJ, Jung KC, Kim SY, Youn YK

  • KMID: 2324841
  • J Korean Surg Soc.
  • 2012 Jun;82(6):389-393.
Exclusively dopamine producing retroperitoneal paragangliomas are extremely rare. We have experienced the first Korean case managed successfully based on the proper evaluation. A 26-year-old female patient came to our attention...
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Vision of Thyroid Surgery: Past, Present and Future

Choi JY, Youn YK

We are presenting perspectives of how thyroid surgery has evolved from the past to the future. Technological process in thyroid surgery is the history of modern surgery and the evolution...
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Berberine Inhibited the Growth of Thyroid Cancer Cell Lines 8505C and TPC1

Park KS, Kim JB, Bae J, Park SY, Jee HG, Lee KE, Youn YK

PURPOSE: Thyroid cancer is the most common malignancy in Korean females and can be treated with good prognosis. However, drugs to treat aggressive types of thyroid cancer such as poorly...
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Development of a canine model for recurrent laryngeal injury by harmonic scalpel

Lee KE, Jee HG, Kim HY, Park WS, Park SH, Youn YK

Various energy devices had been used in thyroid surgery. Aim of study is to develop canine model for recurrent laryngeal nerve injury by harmonic scalpel and to evaluate feasibility of...
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Endoscopic Thyroidectomy via Bilateral Axillo- Breast Approach in Papillary Thyroid Carcinoma

Cheon BS, Kim JH, Park KS, Bae SY, Jung SI, Yoo YB, Yang JH, Youn YK

PURPOSE: The aim of this study was to evaluate the operative feasibility and safety of endoscopic thyroidectomy via bilateral axillo breast approach (BABA) compared to conventional thyroidectomy in papillary thyroid...
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Antiproliferation and Redifferentiation in Thyroid Cancer Cell Lines by Polyphenol Phytochemicals

Kang HJ, Youn YK, Hong MK, Kim LS

Thyroid carcinogenesis is accompanied by loss of thyroid-specific functions and refractory to radioiodine and thyroid stimulating hormone (TSH) suppression therapy. Redifferentiating agents have been shown to inhibit tumor growth and...
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The Author Response: Antiproliferation and Redifferentiation in Thyroid Cancer Cell Line by Polyphenol Phytochemicals

Kang HJ, Youn YK, Hong MK, Kim LS

No abstract available.
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