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Correlation between Morphologic Grading and Euploidy Rates of Blastocysts, and Clinical Outcomes in In Vitro Fertilization Preimplantation Genetic Screening

Kim MK, Park JK, Jeon Y, Choe SA, Lee HJ, Kim J, Chang EM, Kim JW, Lyu SW, Kim JY, Kwak IP, Lee WS, Yoon TK

BACKGROUND: The standard morphological evaluation has been widely used for embryo selection, but it has limitations. This study aimed to investigate the correlation between morphologic grading and euploidy rate of...
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Could surgical management improve the IVF outcomes in infertile women with endometrioma?: a review

Park HJ, Kim H, Lee GH, Yoon TK, Lee WS

Endometriosis is a chronic inflammatory condition that affects fertility and could be toxic to the ovary. Endometrioma per se and surgical interventions for endometrioma significantly reduce the ovarian reserve. Therefore,...
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The meaning of anti-Müllerian hormone levels in patients at a high risk of poor ovarian response

Park HJ, Lee GH, Gong DS, Yoon TK, Lee WS

Measurements of ovarian reserve play an important role in predicting the clinical results of assisted reproductive technology (ART). The ideal markers of ovarian reserve for clinical applications should have high...
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Application of serum anti-Müllerian hormone levels in selecting patients with polycystic ovary syndrome for in vitro maturation treatment

Seok HH, Song H, Lyu SW, Kim YS, Lee DR, Lee WS, Yoon TK

OBJECTIVE: The purpose of this study was to identify useful clinical factors for the identification of patients with polycystic ovary syndrome (PCOS) who would benefit from in vitro maturation (IVM)...
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Chronic endometritis and infertility

Park HJ, Kim YS, Yoon TK, Lee WS

Chronic endometritis (CE) is a condition involving the breakdown of the peaceful co-existence between microorganisms and the host immune system in the endometrium. A majority of CE cases produce no...
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Anti-Mullerian hormone levels as a predictor of clinical pregnancy in in vitro fertilization/intracytoplasmic sperm injection-embryo transfer cycles in patients over 40 years of age

Park HJ, Lyu SW, Seok HH, Yoon TK, Lee WS

OBJECTIVE: The aim of the current study was to determine the predictive value of anti-Mullerian hormone (AMH) levels for pregnancy outcomes in patients over 40 years of age who underwent...
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Spontaneous ovarian hyperstimulation syndrome following a thawed embryo transfer cycle

Kim MK, Won HJ, Shim SH, Cha DH, Yoon TK

This article reports a case of spontaneous ovarian hyperstimulation syndrome (OHSS) following a thawed embryo transfer cycle. OHSS, a potentially life-threatening condition, is an iatrogenic complication of controlled ovarian stimulation;...
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In vitro maturation of human oocytes: Its role in infertility treatment and new possibilities

Chang EM, Song HS, Lee DR, Lee WS, Yoon TK

IVM refers to the maturation of immature oocytes in culture after their recovery from small antral follicles at the stage prior to selection and dominance. IVM requires little or no...
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Correlation between Expression of Glucose Transporters in Granulosa Cells and Oocyte Quality in Women with Polycystic Ovary Syndrome

Kim E, Seok HH, Lee SY, Lee DR, Moon J, Yoon TK, Lee WS, Lee KA

BACKGROUND: The glucose transporters (GLUTs) exhibit different tissue-specific expression. This study aimed to investigate the types of GLUTs expressed in human granulosa cells (GCs) obtained from women with polycystic ovary...
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A healthy delivery of twins by assisted reproduction followed by preimplantation genetic screening in a woman with X-linked dominant incontinentia pigmenti

Kim MJ, Lyu SW, Seok HH, Park JE, Shim SH, Yoon TK

The purpose of this study is to report a successful twin pregnancy and delivery in a female patient with X-linked dominant incontinentia pigmenti (IP) who underwent assisted reproductive technology followed...
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Leprous Neuropathy Associated with Predominant Proprioceptive Sensory Loss

Yoon TK, Jo HY, Yuk JW, Shin JH, Kim DS

Some patients with leprosy may present with atypical features, such as isolated peripheral neuropathy without skin lesions, or marked proprioceptive dysfunction. We report a 56-year-old female who presented with predominant...
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Reversible Infertility Associated with Testosterone Therapy for Symptomatic Hypogonadism in Infertile Couple

Bang JK, Lim JJ, Choi J, Won HJ, Yoon TK, Hong JY, Park DS, Song SH

PURPOSE: Androgen replacement therapy has been shown to be safe and effective for most patients with testosterone deficiency. Male partners of infertile couples often report significantly poorer sexual activity and...
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A case of the rare variant of Klinefelter syndrome 47,XY,i(X)(q10)

Song SH, Won HJ, Yoon TK, Cha DH, Shim JY, Shim SH

Klinefelter syndrome is the most common genetic form of male hypogonadism, but the phenotype becomes evident only after puberty. It is characterized by infertility, small testes, sparse body and facial...
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Current status of assisted reproductive technology in Korea, 2009

Committee for Assisted Reproductive Technology, Korean Society of Obstetrics and Gynecology, Choi YM, Chun SS, Han HD, Hwang JH, Hwang KJ, Kang IS, Kim DW, Kim KC, Kim T, Kwon HC, Lee WD, Lee JH, Lee KS, Lee GH, Lee SH, Lee YI, Min EG, Moon HS, Moon SY, Roh SI, Yoon TK

Great advances have been made in the field of assisted reproductive technology (ART) since the first in vitro fertilization (IVF) baby was born in Korea in the year of 1985....
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Function of the pentose phosphate pathway and its key enzyme, transketolase, in the regulation of the meiotic cell cycle in oocytes

Kim Y, Kim EY, Seo YM, Yoon TK, Lee WS, Lee KA

OBJECTIVE: Previously, we identified that transketolase (Tkt), an important enzyme in the pentose phosphate pathway, is highly expressed at 2 hours of spontaneous maturation in oocytes. Therefore, this study was...
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Isodicentric Y Chromosome Mosaic with Normal Y Chromosome in an Infertile Male Patient: A Case Report and Review of the Literatures

Kim JW, Bak CW, Park SH, Yoon TK, Cha DH, Shim SH

  • KMID: 2329531
  • J Reprod Endocrinol.
  • 2012 Apr;4(1):49-55.
Among the structural abnormalities affecting Y chromosome, isodicentric chromosomes are the most common. The phenotype range from infertile male to Turner-like female through mixed gonadal dysgenesis. The case of a...
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What is the best treatment of heterotopic cervical pregnancies for a successful pregnancy outcome?

Kim JW, Park HM, Lee WS, Yoon TK

Heterotopic pregnancy is rare event and the risk is increased with assisted reproductive technology procedures. Heterotopic cervical pregnancy is even more unusual. We report a rare case of heterotopic cervical...
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Efficiency of laser-assisted intracytoplasmic sperm injection in a human assisted reproductive techniques program

Choi KH, Lee JH, Yang YH, Yoon TK, Lee DR, Lee WS

OBJECTIVE: Laser-assisted intracytoplasmic sperm injection (LA-ICSI), also known as micro-opening or thinning of the zona pellucida (ZP) prior to ICSI, may help to reduce mechanical damage to the oocyte during...
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Functions of PIWI proteins in spermatogenesis

Bak CW, Yoon TK, Choi Y

Recently, a significant understanding of the molecular mechanisms regulating spermatogenesis has been achieved utilizing small RNA molecules (small RNAs), including small interfering RNAs (siRNAs), microRNAs (miRNAs), and Piwi-interacting RNAs (piRNAs)...
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Effects of various combinations of cryoprotectants and cooling speed on the survival and further development of mouse oocytes after vitrification

Cha SK, Kim BY, Kim MK, Kim YS, Lee WS, Yoon TK, Lee DR

OBJECTIVE: The objectives of this study were to analyze efficacy of immature and mature mouse oocytes after vitrification and warming by applying various combinations of cryoprotectants (CPAs) and/or super-rapid cooling...
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