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Biomarkers and diagnostic tools for lung cancer

Lee SH, Lee EH, Kim EY, Choi YJ, Cha YJ, Chang YS

Lung cancer is the leading cause of cancer-related deaths in developing to advanced countries worldwide. The incidence rate of lung cancer in Korea has been increasing steadily since 1997. Statistics...
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Single incision laparoscopic totally extraperitoneal hernioplasty: lessons learned from 1,231 procedures

Lee YJ, Kim JH, Kim CH, Lee GR, Lee YS, Kim HJ

Purpose: Although there are many articles about single incision laparoscopic (SIL) hernioplasty, a large-scale study or article about its long-term outcome has not been reported yet. The aim of this...
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Clinical implication and risk factor of pneumonia development in mild coronavirus disease 2019 patients

Lee HW, Yoon SY, Lee JK, Park TY, Kim DK, Chung HS, Heo EY

Background/Aims Although a majority of coronavirus disease 2019 (COVID-19) cases were characterized as mild, data assessing the development of pneumonia in mild COVID-19 patients are limited. We aimed to examine the...
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Sarcopenia as a Predictor of Prognosis in Early Stage Ovarian Cancer

Chae SH, Lee C, Yoon SH, Shim SH, Lee SJ, Kim SN, Chung S, Lee JY

Background: To identify sarcopenia as a predictive prognostic factor of ovarian cancer in terms of survival outcome in patients with early-stage ovarian cancer. Methods: Data of Konkuk University Medical Center from...
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Fumonisin B1-Induced Toxicity Was Not Exacerbated in Glutathione Peroxidase-1/Catalase Double Knock Out Mice

Yayeh T, Jeong HR, Park YS, Moon S, Sur B, Yoo HS, Oh S

Fumonisin B1 (FB1) structurally resembles sphingolipids and interferes with their metabolism leading to sphingolipid dysregulation. We questioned if FB1 could exacerbate liver or kidney toxicities in glutathione peroxidase 1 (Gpx1)...
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Current Status and Reform Tasks in Life Cycle Management of Korean Health Technology for the Fourth Industrial Revolution Era

Kim A, Kim EJ, Yoon SJ

Entering the fourth industrial revolution era, health technology is rapidly developing and the people's needs for medical services are gradually increasing. Establishing a life cycle management of health technology has...
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Stability of bimaxillary surgery involving intraoral vertical ramus osteotomy with or without presurgical miniscrew-assisted rapid palatal expansion in adult patients with skeletal Class III malocclusion

Ahn YS, Choi SH, Lee KJ, Jung YS, Baik HS, Yu HS

Objective: The aim of this study was to evaluate the stability of bimaxillary surgery involving bilateral intraoral vertical ramus osteotomy performed with or without presurgical miniscrew-assisted rapid palatal expansion (MARPE)...
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Autologous Retinal Flap Transplantation of a Refractory Giant Macular Hole with Retinal Detachment

Lee GW, Yoon SH, Kim YY

Purpose: A giant macular hole with retinal detachment occurred in a patient who had undergone several surgical treatments for retinal detachment, macular hole, and complicated cataracts. Here we report a...
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A semi-automatic cell type annotation method for single-cell RNA sequencing dataset

Kim W, Yoon SM, Kim S

Single-cell RNA sequencing (scRNA-seq) has been widely applied to provide insights into the cell-by-cell expression difference in a given bulk sample. Accordingly, numerous analysis methods have been developed. As it...
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Prognostic Value of Coronary CT Angiography forPredicting Poor Cardiac Outcome in Stroke Patientswithout Known Cardiac Disease or Chest Pain:The Assessment of Coronary Artery Disease in StrokePatients Study

Yoon SH, Kim E, Jeon Y, Yi SY, Bae HJ, Jang IK, Lee JM, Yoo SM, White CS, Chun EJ

Objective: To assess the incremental prognostic value of coronary computed tomography angiography (CCTA) in comparison toa clinical risk model (Framingham risk score, FRS) and coronary artery calcium score (CACS) for...
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Strong association between herpes simplex virus-1 and chemotherapy-induced oral mucositis in patients with hematologic malignancies

Hong J, Park HK, Park S, Lee A, Lee YH, Shin DY, Koh Y, Choi JY, Yoon SS, Choi Y, Kim I

Background/Aims: A link between oral cavity infections and chemotherapy-induced oral mucositis (CIOM) in patients with hematological malignancies (HMs) undergoing intensive chemotherapy (IC) or hematopoietic stem cell transplantation (HSCT) has been...
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Differential efficacy between stenting and plain balloon angioplasty for femoropopliteal disease with or without total occlusion

Chae IH, Yoon CH, Ko YG, Min PK, Lee JH, Yu CW, Lee SW, Lee SR, Choi SH, Koh YS, Choi D

Background/Aims: Whether the presence of chronic total occlusion (CTO) affects patency after stenting in femoropopliteal lesions is unknown. We determined the effects of plain balloon angioplasty (POBA) in comparison with...
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Impact of early anti-TNF use on clinical outcomes in Crohn’s disease: a nationwide population-based study

Jung YS, Han M, Park S, Cheon JH

Background/Aims: The optimal timing for initiation of anti-tumor necrosis factor (TNF) therapy in Crohn’s disease (CD) is still debated. Little is known about the clinical outcomes of early versus late...
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Surgical skin adhesive bond is safe and feasible wound closure method to reduce surgical site infection following minimally invasive colorectal cancer surgery

Lee CS, Han SR, Kye BH, Bae JH, Koh W, Lee IK, Lee DS, Lee YS

Purpose: Minimally invasive colorectal surgery had reduced the rate of surgical site infection. The use of surgical skin adhesive bond (2-octyl cyanoacrylate) for wound closure reduces postoperative pain and provides...
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Descriptive Analysis of Histiocytic and Dendritic Cell Neoplasms: A Single-Institution Experience

Kim HM, Yang WI, Lyu CJ, Hahn SM, Yoon SO

Purpose: Histiocytic and dendritic cell neoplasms are rare hematologic tumors. This study aimed to describe the epidemiologic features of the entire spectrum of histiocytic and dendritic cell neoplasms, including clinicopathological variables...
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Synovial Cell Migration is Associated with B Cell Activating Factor Expression Increased by TNFα or Decreased by KR33426

Lee J, Yoon SS, Thuy PX, Moon EY

Fibroblast-like synoviocytes (FLS) play a crucial role in initiating rheumatoid arthritis. B-cell activating factor (BAFF) plays a role in FLS survival as well as in B cell maturation and maintenance....
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Laparoscopic Hiatal Hernia Repair and Roux-en-Y Conversion for Refractory Duodenogastroesophageal Reflux after Billroth I Distal Gastrectomy

Park JM, Yoon SJ, Kim JW, Chi KC

Distal gastrectomy with Billroth I or II reconstruction may cause duodenogastroesophageal reflux (DGER), thereby resulting in digestive or respiratory symptoms. The mainstay of treatment is medication with proton pump inhibitors....
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Serial Assays of QuantiFERON-TB Gold In-Tube and QuantiFERON-TB Gold-Plus in Subjects Exposed to Patients with Active Tuberculosis

Moon HW, Yi A, Yoon S, Kim H, Chung HJ, Hur M, Yun YM, Yoo KH

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The Efficacy of P2Y12 Reactive Unit to Predict the Periprocedural Thromboembolic and Hemorrhagic Complications According to Clopidogrel Responsiveness and Safety of Modification of Dual Antiplatelet Therapy : A Meta-Analysis

Kim HJ, Oh JS, Park SQ, Yoon SM, Ahn HS, Kim BT

The efficacy of P2Y12 reaction unit (PRU) of VerifyNow still remains as a controversial issue in neurointervention. So we investigated the usefulness of PRU of VerifyNow to predict the peri-procedural...
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Isolation and molecular characterizations of canine distemper virus from a naturally infected Korean dog using Vero cells expressing dog signaling lymphocyte activation molecule

Yang DK, Kim HH, Lee S, Yoon YS, Park J, Oh D, Yoo JY, Ji M, Han B, Oh S, Hyun BH

Background: Canine distemper virus (CDV) infection results in high morbidity and mortality in dogs. There has been no report about Isolation of Korean CDV since 1980 in Korea. Objectives: To investigate...
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