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Systemically administered neurotensin receptor agonist produces antinociception through activation of spinally projecting serotonergic neurons in the rostral ventromedial medulla

Li Y, Kang DH, Kim WM, Lee HG, Kim SH, You HE, Choi JI, Yoon MH

Background: Supraspinal delivery of neurotensin (NTS), which may contribute to the effect of a systemically administered agonist, has been reported to be either pronociceptive or antinociceptive. Here, we evaluated the...
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Prostaglandin D2 contributes to cisplatin-induced neuropathic pain in rats via DP2 receptor in the spinal cord

Li Y, Kim WM, Kim SH, You HE, Kang DH, Lee HG, Choi JI, Yoon MH

Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a major reason for stopping or changing anticancer therapy. Among the proposed pathomechanisms underlying CIPN, proinflammatory processes have attracted increasing attention. Here we assessed...
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Changes in the Ganglion Cell-inner Plexiform Layer after Consecutive Intravitreal Injections of Anti-vascular Endothelial Growth Factor in Age-related Macular Degeneration Patients

Kim SY, Yoon MH, Chin HS

PURPOSE: To investigate the effect of intravitreal anti-vascular endothelial growth factor (VEGF) injections on ganglion cell-inner plexiform layer (GCIPL) thickness in patients with age-related macular degeneration (AMD). METHODS: This retrospective study...
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Antinociceptive role of neurotensin receptor 1 in rats with chemotherapy-induced peripheral neuropathy

Yin M, Kim YO, Choi JI, Jeong S, Yang SH, Bae HB, Yoon MH

Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a major side effect of anti-cancer drugs. Neurotensin receptors (NTSRs) are widely distributed within the pain circuits in the central nervous system. The purpose...
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Effect of sec-O-glucosylhamaudol on mechanical allodynia in a rat model of postoperative pain

Koh GH, Song H, Kim SH, Yoon MH, Lim KJ, Oh SH, Jung KT

BACKGROUND: This study was performed in order to examine the effect of intrathecal sec-O-glucosylhamaudol (SOG), an extract from the root of the Peucedanum japonicum Thunb., on incisional pain in a...
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Late Postoperative Opacification of Multifocal Intraocular Lens after Vitrectomy in a Diabetic Patient

Yoon MH, Kim SY, Chin HS

PURPOSE: We report a case of late opacity of an AT LISA intraocular lens after vitrectomy in a diabetic patient. CASE SUMMARY: A 61-year-old man presented with blurring in the left...
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Lipid-Core Plaque Assessed by Near-Infrared Spectroscopy and Procedure Related Microvascular Injury

Yang HM, Yoon MH, Lim HS, Seo KW, Choi BJ, Choi SY, Hwang GS, Tahk SJ

BACKGROUND AND OBJECTIVES: Microvascular damage due to distal embolization during percutaneous coronary intervention (PCI) is an important cause of periprocedural myocardial infarction. We assessed the lipid-core plaque using near-infrared spectroscopy...
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Report on the External Quality Assessment Scheme for Molecular Diagnostics in Korea (2017)

Kim MJ, Yoon MH, Song JY, Cho SI, Park SS, Seong MW

Quality control for genetic analysis has become more important with a drastic increase in testing volume and clinical demands. The molecular diagnostics division of the Korean Association of Quality Assurance...
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Invasive Aspergillosis Associated Bacterial Infection in the Nasal Septum After Sphenoid Sinus Surgery

Sohn HG, Yoon MH, Kim TE, Yeo NK

Nasal septal infection can result from progression of a fungal infection from the adjacent sinuses. Nasal septal fungal abscesses complicating nasal trauma, surgical procedures, sinus, and dental infections have previously...
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Differential expression of spinal γ-aminobutyric acid and opioid receptors modulates the analgesic effects of intrathecal curcumin on postoperative/inflammatory pain in rats

Ju J, Shin JY, Yoon JJ, Yin M, Yoon MH

BACKGROUND: Curcumin is traditionally used as an herbal medicine. We explored the efficacy of intrathecal curcumin in relieving both postoperative and inflammatory pain and elucidated the mechanisms of action of...
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Ischemia-based Coronary Revascularization: Beyond Anatomy and Fractional Flow Reserve

Lim HS, Seo KW, Yoon MH, Yang HM, Tahk SJ

Treatment strategies for patients with coronary artery disease (CAD) should be based on objective evidence of inducible ischemia in the subtended myocardium to improve clinical outcomes, symptoms, and cost-effectiveness. Fractional...
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Antinociceptive effect of intrathecal sec-O-glucosylhamaudol on the formalin-induced pain in rats

Kim SH, Jong HS, Yoon MH, Oh SH, Jung KT

BACKGROUND: The root of Peucedanum japonicum Thunb., a perennial herb found in Japan, the Philippines, China, and Korea, is used as an analgesic. In a previous study, sec-O-glucosylhamaudol (SOG) showed...
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Comparison of the Recurrence of RRD in PPV Combined Cataract Surgery with PPV Alone, and Risk Factors in PPV Combined Cataract Surgery

Park HI, Yoon MH, Chin HS

PURPOSE: To compare the recurrence percentage and risk factors of recurrence in rhegmatogenous retinal detachment (RRD) after pars plana vitrectomy (PPV) by in two groups of patients according to combined...
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Clinical and Angiographic Outcomes of the First Korean-made Sirolimus-Eluting Coronary Stent with Abluminal Bioresorbable Polymer

Yang HM, Seo KW, Yoon J, Kim HS, Chang K, Lim HS, Choi BJ, Choi SY, Yoon MH, Lee SH, Ahn SG, Youn YJ, Lee JW, Koo BK, Park KW, Yang HM, Han JK, Seung KB, Chung WS, Kim PJ, Koh YS, Park HJ, Tahk SJ

BACKGROUND AND OBJECTIVES: This trial evaluated the safety and efficacy of the Genoss drug-eluting coronary stent. METHODS: This study was a prospective, multicenter, randomized trial with a 1:1 ratio of Genoss...
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Angiographic spontaneous pseudo-resolution of a coronary artery aneurysm after implantation of a sirolimus-eluting stent

Choi YW, Lim HS, Tahk SJ, Yoon MH, Yang HM, Jin XJ

No abstract available.
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The Role of Spinal Dopaminergic Transmission in the Analgesic Effect of Nefopam on Rat Inflammatory Pain

Kim DY, Chae JW, Lim CH, Heo BH, Park KS, Lee HG, Choi JI, Yoon MH, Kim WM

BACKGROUND: Nefopam has been known as an inhibitor of the reuptake of monoamines, and the noradrenergic and/or serotonergic system has been focused on as a mechanism of its analgesic action....
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Anatomical Discrepancy Between The Coronary Sinus and the Mitral Annulus by Fluoroscopy

Kim JW, Hwang GS, Seo KW, Park JS, Yang HM, Lim HS, Choi BJ, Choi SY, Yoon MH, Tahk SJ

BACKGROUND AND OBJECTIVES: Intracardiac electrocardiograms (ECGs) from the coronary sinus (CS) provide important information for identifying a left-sided bypass tract. However, a previous study revealed an anatomical discrepancy between the...
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Effects of Intravitreal Injection of Bevacizumab or Ranibizumab on Systemic Circulation

Yoon MH, Kim YJ, Lee SY, Lee KW, Chin HS

PURPOSE: The purpose of this study was to evaluate the systemic effects of ranibizumab and bevacizumab by examining the plasma levels of anti-vascular endothelial growth factor (anti-VEGF) and VEGF before...
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A Case of Epithelioid Hemangioendothelioma of the Nasal Cavity

Kim EH, Yoon MH, Yeo NK

Epithelioid hemangioendothelioma (EHE), a rare vascular tumor that is both clinically and histologically an intermediate between angiosarcoma and hemangioma, was first described by Sharon Weiss and Franz Enzinger. It is...
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Time Variance of Electrocardiographic Transmural Dispersion in Acute Myocardial Infarction

Park JS, Hwang GS, Kim SM, Seo KW, Choi BJ, Choi SY, Yoon MH, Shin JH, Tahk SJ

BACKGROUND AND OBJECTIVES: The mechanism responsible for lethal ventricular arrhythmia (LVA) after acute myocardial infarction (AMI) remains unclear. SUBJECTS AND METHODS: The corrected QT interval (QTc) and interval from the peak...
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