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Burnout as a Mediator in the Relationship between Work-Life Balance and Empathy in Healthcare Professionals

Seo HY, Lee DW, Nam S, Cho Sj, Yoon JY, Hong YC, Lee N

Objective This cross-sectional study aimed to 1) explore the relationships among work-life balance (WLB), burnout, and empathy and 2) investigate the roles of the subtypes of burnout relating to WLB...
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Prognostic Value of Tumor Regression Grade on MR in Rectal Cancer: A Large-Scale, Single-Center Experience

Yoen H, Park HE, Kim SH, Yoon JH, Hur BY, Bae JS, Kim JH, Oh HJ, Han JK

Objective: To determine the prognostic value of MRI-based tumor regression grading (mrTRG) in rectal cancer compared withpathological tumor regression grading (pTRG), and to assess the effect of diffusion-weighted imaging (DWI)...
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The clinical meaning of pre- and post-ablation thyroglobulin levels at first radioiodine therapy in patients with papillary thyroid cancer

Kim HK, Yoon JH, Cho JS, Kwon SY, Yoo SW, Kang HC

Background/Aims: This study was conducted to identify prognostic factors in patients with papillary thyroid cancer (PTC) at the time of first radioactive iodine (RAI) therapy, and to evaluate the clinical...
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Effects of Functions of Daily Living, Depression, and Anxiety on Catastrophizing Pain among Patients Undergoing Lumbar Spinal Surgery

Yoon JE, Cho OH

Purpose: The aim of this study was to investigate the influence of daily life functions, anxiety, and depression on pain catastrophizing among patients undergoing lumbar spinal surgery. Methods: This study...
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Deep Learning Algorithm for Automated Segmentationand Volume Measurement of the Liver and Spleen UsingPortal Venous Phase Computed Tomography Images

Ahn Y, Yoon JS, Lee SS, Suk HI, Son JH, Sung YS, Lee Y, Kang BK, Kim HS

Objective: Measurement of the liver and spleen volumes has clinical implications. Although computed tomography (CT)volumetry is considered to be the most reliable noninvasive method for liver and spleen volume measurement,...
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Inhibition of Ceramide Accumulation in Podocytes by Myriocin Prevents Diabetic Nephropathy

Woo CY, Baek JY, Kim AR, Hong CH, Yoon JE, Kim HS, Yoo HJ, Park TS, Kc R, Lee KU, Koh EH

Background: Ceramides are associated with metabolic complications including diabetic nephropathy in patients with diabetes. Recent studies have reported that podocytes play a pivotal role in the progression of diabetic nephropathy. Also,...
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Comparison of point and 2-dimensional shear wave elastography for the evaluation of liver fibrosis

Lee SM, Kim MJ, Yoon JH, Hong W, Ha HI, Lee K, Choe JY, Lee JW, Yoon SY, Han J

Purpose: This study aimed to assess the technical performance of ElastQ Imaging compared with ElastPQ and to investigate the correlation between liver stiffness (LS) values obtained using these two techniques. Methods:...
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ERK Regulates NeuroD1-mediated Neurite Outgrowth via Proteasomal Degradation

Lee Ty, Cho IS, Bashyal N, Naya FJ, Tsai MJ, Yoon JS, Choi JM, Park CH, Kim SS, Suh-Kim H

  • KMID: 2503980
  • Exp Neurobiol.
  • 2020 Jun;29(3):189-206.
  • doi: 10.5607/en20021
Neurogenic differentiation 1 (NeuroD1) is a class B basic helix-loop-helix (bHLH) transcription factor and regulates differentiation and survival of neuronal and endocrine cells by means of several protein kinases, including...
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Prognostic impact of hepatitis B or C on intrahepatic cholangiocarcinoma

Seo JW, Kwan BS, Cheon YK, Lee TY, Shim CS, Kwon SY, Choe WH, Yoo BC, Yoon JM, Lee JH

Background/Aims: Intrahepatic cholangiocarcinoma (ICC) is the second-most common primary liver malignancy, arising from the peripheral intrahepatic bile duct epithelium. Hepatitis B virus (HBV) or hepatitis C virus (HCV) may be...
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Identification of Free-Living Amoebas in Tap Water of Buildings with Storage Tanks in Korea

Lee DI, Park SH, Baek JH, Yoon JW, Jin SI, Han KE, Yu HS

Free-living amoebas (FLAs) can cause severe disease in humans and animals when they become infected. However, there are no accurate survey reports on the prevalence of FLAs in Korea. In...
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Macular Microvasculature in High Myopia without Pathologic Changes: An Optical Coherence Tomography Angiography Study

Min CH, Al-Qattan HM, Lee JY, Kim JG, Yoon YH, Kim YJ

Purpose To investigate macular microvasculature changes using optical coherence tomography angiography (OCTA) and analyze their correlation with the structural parameters in highly myopic eyes. Methods We measured the area of the foveal avascular...
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Reproducibility of ultrasound attenuation imaging for the noninvasive evaluation of hepatic steatosis

Yoo J, Lee JM, Joo I, Lee DH, Yoon JH, Kang HJ, Ahn SJ

Purpose: The purpose of this study was to evaluate the intra-observer reproducibility of ultrasound attenuation imaging (ATI) for the noninvasive assessment of hepatic steatosis in patients with suspected hepatic steatosis...
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Neurogenin-1 Overexpression Increases the Therapeutic Effects of Mesenchymal Stem Cells through Enhanced Engraftment in an Ischemic Rat Brain

Kim GH, Subash M, Yoon JS, Jo D, Han J, Hong JM, Kim SS, Kim HS

Background and Objectives: Stem cell therapy is a promising strategy for treating neurological diseases but its effectiveness is influenced by the route of administration and the characteristics of the stem...
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Mutation of ten-eleven translocation-2 is associated with increased risk of autoimmune disease in patients with myelodysplastic syndrome

Oh YJ, Shin DY, Hwang SM, Kim SM, Im K, Park HS, Kim JA, Song YW, Márquez A, Martín J, Lee DS, Park JK

Background/Aims: Myelodysplastic syndrome (MDS) is caused by genetic and epigenetic alteration of hematopoietic precursors and immune dysregulation. Approximately 20% of patients with MDS develop an autoimmune disease (AID). Here, we...
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Posterior dental compensation and occlusal function in adults with different sagittal skeletal malocclusions

Hwang S, Choi YJ, Jung S, Kim S, Chung CJ, Kim KH

OBJECTIVE: The aim of this study was to compare posterior tooth inclinations, occlusal force, and contact area of adults with different sagittal malocclusions. METHODS: Transverse skeletal parameters and posterior tooth inclinations...
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The Fourth Industrial Revolution and Changes of Pharmacists’ Roles in the Future

Kim Y, Yoon JH

The fourth industrial revolution, with its characteristics of “hyper-connectivity”, “hyper-intelligence” and “automation”, is a hot topic worldwide. It will fundamentally change industry, economy, and business models through technological innovations, such...
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Practical Utility of D-dimer Test for Venous Thromboembolism in Systemic Lupus Erythematosus Depends on Disease Activity: a Retrospective Cohort Study

Oh YJ, Park EH, Park JW, Song YW, Lee EB

Background: The D-dimer test is a screening tool for venous thromboembolism (VTE); however, its utility for patients with systemic lupus erythematosus (SLE) remains unclear. Here, we examined the utility of the D-dimer...
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Transient Homonymous Superior Quadrantanopsia in Nonketotic Hyperglycemia: A Case Report and Systematic Review

Lee SU, Lee J, Yoon JEY, Kim HJ, Choi JY, Yun CH, Kim JS

Background and Purpose: Nonketotic hyperglycemia often causes transient visual field defects, but only scattered anecdotes are available in the literature. Methods: We report a patient with homonymous superior quadrantanopsia due to...
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Interventional treatment of a huge hepatic artery aneurysm as an unusual cause of upper gastrointestinal bleeding

Kwon SH, Yoon J, Noh SY, Ahn HJ, Oh JH

A 61-year-old man presented to our hospital with abdominal pain and melena. He showed no obvious source of bleeding on gastroduodenoscopy. Computed tomography and conventional angiography revealed a huge aneurysm...
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Assessment of liver fibrosis using 2-dimensional shear wave elastography: a prospective study of intra- and inter-observer repeatability and comparison with point shear wave elastography

Yoo J, Lee JM, Joo I, Yoon JH

Purpose: The purpose of this study was to prospectively investigate the intra- and interobserver repeatability of a new 2-dimensional (2D) shear wave elastography (SWE) technique (S-Shearwave Imaging) for assessing liver...
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