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Comparison of age‐dependent alterations in thioredoxin 2 and thioredoxin reductase 2 expressions in hippocampi between mice and rats

Yoo YH, Kim DW, Chen BH, Sim H, Kim B, Lee JC, Ahn JH, Park Y, Cho JH, Kang IJ, Won MH, Lee TK

Background Aging is one of major causes triggering neurophysiological changes in many brain substructures, including the hippocampus, which has a major role in learning and memory. Thioredoxin (Trx) is a class...
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Effects of quadriceps angle on patellofemoral contact pressure

Yoo YH, Lee SJ, Jeong Sw

Background: An inappropriate Q angle may affect the biomechanics of the canine patellofemoral joint. Objectives: The purpose of this study was to evaluate the effects of changes in quadriceps angle (Q...
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High fat diet accelerates and exacerbates microgliosis and neuronal damage/death in the somatosensory cortex after transient forebrain ischemia in gerbils

Seo WJ, Ahn JH, Lee TK, Kim B, Lee JC, Park JH, Yoo YH, Shin MC, Cho JH, Won MH, Park Y

Obesity has been known as an independent risk factor for stroke. Effects of high-fat diet (HFD)-induced obesity on neuronal damage in the somatosensory cortex of animal models of cerebral ischemia...
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Evaluation of pneumonia management effectiveness associated withinternal medicine management changes in the emergency department:a retrospective cohort study using a historically controlled group

Yoo JW, Ryu S, Jeong WJ, Cho YC, Ahn HJ, Cho SW, Oh SK, Park JS, Yoo YH

  • KMID: 2500274
  • J Korean Soc Emerg Med.
  • 2020 Apr;31(2):246-253.
Objective: In Korea, many hospitals have recently changed the process of internal medicine management in the emergency department (ED) because of reduced manpower, raising concerns regarding the decreased quality of medical care....
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Gelatinous Transformation of Bone Marrow Mimicking Malignant Marrow-Replacing Lesion on Magnetic Resonance Imaging in a Patient without Underlying Devastating Disease

Lee J, Yoo YH, Lee S, Kim HS, Kim S

Gelatinous transformation of bone marrow is characterized by hypoplasia of fat cells with focal loss of hematopoietic cells and deposition of extracellular gelatinous substances. It is known to be associated...
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Interobserver and Test-Retest Reproducibility of T1ρ and T2 Measurements of Lumbar Intervertebral Discs by 3T Magnetic Resonance Imaging

Yoo YH, Yoon CS, Eun NL, Hwang MJ, Yoo H, Peters RD, Chung TS, Lee YH, Suh JS, Kim S

OBJECTIVE: To investigate the interobserver and test-retest reproducibility of T1ρ and T2 measurements of lumbar intervertebral discs using 3T magnetic resonance imaging (MRI). MATERIALS AND METHODS: This study included a total...
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Accuracy of Diffusion Tensor Imaging for Diagnosing Cervical Spondylotic Myelopathy in Patients Showing Spinal Cord Compression

Lee S, Lee YH, Chung TS, Jeong EK, Kim S, Yoo YH, Kim IS, Yoon CS, Suh JS, Park JH

OBJECTIVE: To assess the performance of diffusion tensor imaging (DTI) for the diagnosis of cervical spondylotic myelopathy (CSM) in patients with deformed spinal cord but otherwise unremarkable conventional magnetic resonance...
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Comparison of Multi-Echo Dixon Methods with Volume Interpolated Breath-Hold Gradient Echo Magnetic Resonance Imaging in Fat-Signal Fraction Quantification of Paravertebral Muscle

Yoo YH, Kim HS, Lee YH, Yoon CS, Paek MY, Yoo H, Kannengiesser S, Chung TS, Song HT, Suh JS, Kim S

OBJECTIVE: To assess whether multi-echo Dixon magnetic resonance (MR) imaging with simultaneous T2* estimation and correction yields more accurate fat-signal fraction (FF) measurement of the lumbar paravertebral muscles, in comparison...
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The Histone Deacetylase Inhibitor Trichostatin A Sensitizes Human Renal Carcinoma Cells to TRAIL-Induced Apoptosis through Down-Regulation of c-FLIP(L)

Han MH, Park C, Kwon TK, Kim GY, Kim WJ, Hong SH, Yoo YH, Choi YH

Histone acetylation plays a critical role in the regulation of transcription by altering the structure of chromatin, and it may influence the resistance of some tumor cells to tumor necrosis...
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beta-lapachone-Induced Apoptosis of Human Gastric Carcinoma AGS Cells Is Caspase-Dependent and Regulated by the PI3K/Akt Pathway

Yu HY, Kim SO, Jin CY, Kim GY, Kim WJ, Yoo YH, Choi YH

  • KMID: 2170635
  • Biomol Ther.
  • 2014 May;22(3):184-192.
beta-lapachone is a naturally occurring quinone that selectively induces apoptotic cell death in a variety of human cancer cells in vitro and in vivo; however, its mechanism of action needs...
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Differentiation between Focal Malignant Marrow-Replacing Lesions and Benign Red Marrow Deposition of the Spine with T2*-Corrected Fat-Signal Fraction Map Using a Three-Echo Volume Interpolated Breath-Hold Gradient Echo Dixon Sequence

Kim YP, Kannengiesser S, Paek MY, Kim S, Chung TS, Yoo YH, Yoon CS, Song HT, Lee YH, Suh JS

OBJECTIVE: To assess the feasibility of T2*-corrected fat-signal fraction (FF) map by using the three-echo volume interpolated breath-hold gradient echo (VIBE) Dixon sequence to differentiate between malignant marrow-replacing lesions and...
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A Case of Acquired Zonal Aganglionosis in Adult

Kim WJ, Eun CS, Lee MK, Min SY, Yoo YH, Han DS, Jeon YC, Sohn JH

A chronic intestinal pseudo-obstruction is a rare disorder and a severe digestive syndrome. It is characterized by deranged gut propulsive motility that resembles a mechanical obstruction, but no obstructive process...
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Segmental Adenomyomatosis of Gallbladder: CT Assessment of the Patterns of Cholecystolithiasis

Yoo YH, Yu JS, Chung JJ, Kim JH, Cho ES, Kim DJ, Ahn JH, Kim KW

PURPOSE: To clarify the relationship between the pattern of cholecystolithiasis and the gross features of segmental adenomyomatosis of the gallbladder. MATERIALS AND METHODS: Fifty-five consecutive patients with segmental adenomyomatosis with calcified...
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Re-engineering the mitochondrial genomes in mammalian cells

Yoon YG, Koob MD, Yoo YH

Mitochondria are subcellular organelles composed of two discrete membranes in the cytoplasm of eukaryotic cells. They have long been recognized as the generators of energy for the cell and also...
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Modulation of Apoptosis and Cell Cycle by Synthetic Bile Acid Derivatives

Park SE, Im EO, Choi YH, Kim ND, Yoo YH

  • KMID: 2092912
  • Korean J Anat.
  • 2008 Mar;41(1):1-11.
This paper outlines the current understanding of cell cycle modulation and induction of apoptosis in cancer cells by natural and synthetic bile acid. Bile acid homeostasis is tightly regulated in...
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The expression of TRAIL and its receptors in human osteoarthritic cartilages

Lee SY, Koo JM, Yoo HS, Kim YH, Kim JW, Lee JH, Hong HJ, Kim HI, Park SK, Lee SW, Chung WT, Yoo YH, Huh GY

  • KMID: 1479583
  • Korean J Med.
  • 2008 Mar;74(3):296-304.
BACKGROUND/AIMS: The apoptosis of chondrocytes is assumed to be involved in the pathogenesis of osteoarthritis (OA), and the TNF related apoptosis inducing ligand (TRAIL) is thought to have a pivotal...
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The Importance of Motivation and Dropping Out from Treatment in Constraint-induced Movement Therapy for Stroke Patients

Choi SW, Kim KM, Jang SJ, Kim HJ, Kim SS, Son MO, Oh SY, Yoo YH, Seo JH

  • KMID: 2136456
  • J Korean Acad Rehabil Med.
  • 2008 Feb;32(1):20-25.
OBJECTIVE: To assess the effect of motivation for treatment and to find out causes of dropping out from treatment in performing the constraint-induced movement therapy (CIMT). METHOD: Forty six stroke patients...
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A Case of Intraductal Papilloma in the Parotid Gland

Kang JM, Choi JY, Kang BS, Yoo YH

  • KMID: 2276837
  • Korean J Otorhinolaryngol-Head Neck Surg.
  • 2008 Jan;51(1):99-101.
Intraductal papilloma is a rare benign salivary gland tumor that occurs most commonly in the minor salivary gland. We recently experienced a case of intraductal papilloma arising from the parotid...
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The Increase in Hepatic Uncoupling by Fenofibrate Contributes to a Decrease in Adipose Tissue in Obese Rats

Park MK, Lee HJ, Hong SH, Choi SS, Yoo YH, Lee KI, Kim DK

Fenofibrate is a drug that has been suggested to inhibit weight gain by increasing the catabolism of fatty acid in the hepatic mitochondria. We hypothesized that fenofibrate induces an increase...
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Clinical Consideration of Vestibular Evoked Myogenic Potential in Dizzy Patients

Yoo YH, Bae SC, Seo JH, Chang KH, Yeo SW

  • KMID: 2328967
  • J Korean Bal Soc.
  • 2007 Dec;6(2):176-180.
BACKGROUND AND OBJECTIVES: Vestibular evoked myogenic potential (VEMP) is a relatively new diagnostic tool that is in the process of being investigated in patients with specific vestibular disorders. In this...
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