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Increased 1-Deoxysphingolipids and Skin BarrierDysfunction in the Skin of X-ray or Ultraviolet BIrradiation and Atopic Dermatitis Lesion Could BePrevented by Moisturizer with Physiological LipidMixture

Chung BY, Kim HO, Kang SY, Jung MJ, Kim SW, Yoo KS, Shin KO, Jeong SK, Park CW

Background: Skin diseases characterized by epithelial barrierdysfunction show altered sphingolipid metabolism,which results in changes in the stratum corneum intercellularlipid components and structure. Under pathological conditions,1-deoxysphingolipids form as atypical sphingolipidsfrom de...
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Osteoporotic Conditions Influence the Activity of Adipose-Derived Stem Cells

Park JS, Piao J, Park G, Yoo KS, Hong HS

BACKGROUND: Estrogen deficiency decreases bone density and increases the risk of osteoporosis and fracture, thereby necessitating reconstruction of bone regeneration. As bone marrow mesenchymal stem cell (BMSCs) lose viability and...
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Rho Guanine Nucleotide Exchange Factor 4 (Arhgef4) Deficiency Enhances Spatial and Object Recognition Memory

Yoo KS, Lee K, Lee YS, Oh WJ, Kim HK

  • KMID: 2508470
  • Exp Neurobiol.
  • 2020 Oct;29(5):334-343.
  • doi: 10.5607/en20049
Guanine nucleotide exchange factors (GEFs) play multiple functional roles in neurons. In a previous study, we reported that Arhgef4 (Rho guanine nucleotide exchange factor 4) functioned as a negative regulator...
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Carriage of Staphylococcus schleiferi from canine otitis externa: antimicrobial resistance profiles and virulence factors associated with skin infection

Lee GY, Lee HH, Hwang SY, Hong J, Lyoo KS, Yang SJ

The recent emergence of Staphylococcus schleiferi in dogs with otitis externa or skin and soft tissue infections has become a significant zoonotic issues. In the current study, we investigated 1)...
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Genetic variations in open reading frame 2 gene of porcine circovirus type 2 isolated in Korea during 2016–2017

Kim K, Choi JY, Lyoo KS, Hahn TW

The capsid protein of porcine circovirus type 2 (PCV2) encoded by open reading frame 2 (ORF2) is important for neutralizing activity against PCV2 infection. This study investigated the heterogeneity of...
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Predictors of Malignancy in “Pure” Branch-Duct Intraductal Papillary Mucinous Neoplasm of the Pancreas without Enhancing Mural Nodules on CT Imaging: A Nationwide Multicenter Study

Kim TH, Woo YS, Chon HK, Hwang JH, Yoo KS, Lee WJ, Lee KH, Lee JK, Dong SH, Park CH, Park ET, Moon JH, Kim HG, Cho KB, Kim HJ, Lee SO, Cheon YK, Lee JM, Park JW, Kim MH

BACKGROUND/AIMS: Presence of enhanced mural nodules, which can be visualized using computed tomography (CT), is one of high-risk stigmata in branch-duct intraductal papillary mucinous neoplasms (BD-IPMNs). Conversely, the absence of...
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Vaccination of goats with a combination Salmonella vector expressing four Brucella antigens (BLS, PrpA, Omp19, and SOD) confers protection against Brucella abortus infection

Leya M, Kim WK, Cho JS, Yu EC, Kim YJ, Yeo Y, Lyoo KS, Yang MS, Han SS, Lee JH, Tark D, Hur J, Kim B

Salmonella is an intracellular pathogen with a cellular infection mechanism similar to that of Brucella, making it a suitable choice for use in an anti-Brucella immune boost system. This study...
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Management of Gallstone

Yoo KS

Gallstones are one of the most common diseases worldwide. Recently, the incidence of gallstones has increased and the pattern of gallstones has changed in Korea. Laparoscopic cholecystectomy is the standard...
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Efficacy of preoperative percutaneous cholecystostomy in the management of acute cholecystitis according to severity grades

Kim SY, Yoo KS

BACKGROUND/AIMS: The aim of this retrospective study was to assess the efficacy of percutaneous cholecystostomy (PC) for patients with acute cholecystitis (AC) according to severity. METHODS: A total of 325 patients...
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Duplex nested reverse transcriptase polymerase chain reaction for simultaneous detection of type 2 porcine reproductive and respiratory syndrome virus and porcine circovirus type 2 from tissue samples

Kim HK, Lyoo KS, Huynh TM, Moon HJ, Nguyen VG, Park BK

There are high levels of co-incidence of porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV2) in porcine tissue. This study established a duplex nested reverse...
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Effect of Favorite Music Therapy on Stress Response in Patients Undergoing Hysterectomy

Yang JL, Yoo KS

PURPOSE: The aim of this study was to evaluate the effects of favorite music therapy on the stress response of hysterectomy patients undergoing general anesthesia. METHODS: Date were collected from June...
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MUC Expression in Gallbladder Epithelial Tissues in Cholesterol-Associated Gallbladder Disease

Yoo KS, Choi HS, Jun DW, Lee HL, Lee OY, Yoon BC, Lee KG, Paik SS, Kim YS, Lee J

BACKGROUND/AIMS: Gallstone pathogenesis is linked to mucin hypersecretion and bacterial infection. Several mucin genes have been identified in gallbladder epithelial cells (GBECs). We investigated MUC expression in cholesterol-associated gallbladder disease...
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Biology of Cholangiocytes: From Bench to Bedside

Yoo KS, Lim WT, Choi HS

Cholangiocytes, the lining epithelial cells in bile ducts, are an important subset of liver cells. They are activated by endogenous and exogenous stimuli and are involved in the modification of...
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Risk of Clostridium difficile Infection with the Use of a Proton Pump Inhibitor for Stress Ulcer Prophylaxis in Critically Ill Patients

Ro Y, Eun CS, Kim HS, Kim JY, Byun YJ, Yoo KS, Han DS

BACKGROUND/AIMS: Proton pump inhibitors (PPIs) and histamine-2 receptor antagonists (H2RAs) are commonly prescribed for stress ulcer prophylaxis (SUP) in critically ill patients. Several studies have suggested that the use of...
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Antibody to FcεRIα Suppresses Immunoglobulin E Binding to High-Affinity Receptor I in Allergic Inflammation

Hong JY, Bae JH, Lee KE, Kim M, Kim MH, Kang HJ, Park EH, Yoo KS, Jeong SK, Kim KW, Kim KE, Sohn MH

PURPOSE: High-affinity receptor I (FcεRI) on mast cells and basophils plays a key role in the immunoglobulin E (IgE)-mediated type I hypersensitivity mediated by allergen cross-linking of the specific IgE-FcεRI...
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A Prediction Model of Drug Misuse Behaviors in Community-Dwelling Older Adults

Hong SH, Yoo KS

PURPOSE: This study was designed to construct a model which explains drug misuse behaviors in community-dwelling older adults. METHODS: The design of this research is a cross-sectional study using structure equation...
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The submucosal fibrosis: what does it mean for colorectal endoscopic submucosal dissection?

Kim EK, Han DS, Ro Y, Eun CS, Yoo KS, Oh YH

BACKGROUND/AIMS: Endoscopic submucosal dissection (ESD) allows removal of colorectal epithelial neoplasms en bloc regardless of size. Colorectal ESD is a difficult procedure because of technical difficulties and risks of complications....
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Does Lymphocytic Colitis Always Present with Normal Endoscopic Findings?

Park HS, Han DS, Ro Y, Eun CS, Yoo KS

BACKGROUND/AIMS: Although normal endoscopic findings are, as a rule, part of the diagnosis of microscopic colitis, several cases of macroscopic lesions (MLs) have been reported in collagenous colitis, but hardly...
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The Effects of Foot Reflexology on Arthralgia, Ankylosis, Depression, and Sleep in Community-dwelling Elderly Women with Osteoarthritis

Kim CS, Yoo KS, Hong SH

PURPOSE: This study was conducted to examine the effects of foot reflexology on arthralgia, ankylosis, depression and sleep in community-dwelling elderly women with osteoarthritis. METHODS: The research adopted a non-equivalent control...
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Endoscopic Diagnosis of Pancreatic Cystic Tumors

Yoo KS

Pancreatic cystic neoplasms are frequently recognized on routine screening cross-sectional imaging studies, such as computed tomography (CT) and magnetic resonance imaging (MRI), which can be used in their diagnosis and...
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