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What Did Your Peers Do to You in High School?

Yoo HJ

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A novel KCNH2 frameshift mutation (c.46delG) associated with high risk of sudden death in a family with congenital long QT syndrome type 2

Yoo H, Medina N, von Wulffen M, Ciampi N, Paolucci A, Garro H,  Principato M, Acunzo R,  Carbajales J

Background: The congenital long QT syndrome type 2 is caused by mutations in KCNH2 gene that encodes the alpha subunit of potassium channel Kv11.1. The carriers of the pathogenic variant...
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Psychological Autopsy of Suicide Victims between Interview Methods through Their Family Members versus Review of Their Police Investigation Records

Choi JH, Lee GS, Yoo HL, Seo JS, Kim EJ, Jeon HJ

Objectives This study compared the psychological autopsies of suicide victims through interviews of the bereaved family members and investigations of the police death records. Methods A psychological autopsy was performed using...
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Clinical characteristics of congenital pulmonary airway malformation of the lungs: A single-center study

Yoo HW, Kim SH, Kim YM, Kwak MJ, Kim HY

Purpose: Congenital pulmonary airway malformation (CPAM) is a rare developmental abnormality of the lungs. We investigated clinical characteristics of CPAM based on patient age at diagnosis. Methods: In this retrospective study,...
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Science Goes On, As Life Does

Yoo HJ

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Adaptations in Anatomy Education during COVID-19

Yoo H, Kim D, Lee YM, Rhyu IJ

Background: The impact of coronavirus disease 2019 (COVID-19) has profoundly affected education, with most universities changing face-to-face classes to online formats. To adapt to the COVID-19 pandemic situation, we adopted...
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Inborn Errors of Mitochondrial Fatty Acid Oxidation: Overview from a Clinical Perspective

Yoo HW

Mitochondrial fatty acid β-oxidation (mFAO), which is the major pathway for the degradation of fatty acids and is critical for maintaining energy homeostasis in the human body, consists of carnitine...
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Fumonisin B1-Induced Toxicity Was Not Exacerbated in Glutathione Peroxidase-1/Catalase Double Knock Out Mice

Yayeh T, Jeong HR, Park YS, Moon S, Sur B, Yoo HS, Oh S

Fumonisin B1 (FB1) structurally resembles sphingolipids and interferes with their metabolism leading to sphingolipid dysregulation. We questioned if FB1 could exacerbate liver or kidney toxicities in glutathione peroxidase 1 (Gpx1)...
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Surgical Interventions and Clinical Outcomes of Patients with Trisomy 18: a Single Center Experience

Oh MY, Lee BS, Cha T, Jeong J, Jung E, Kim EAR, Kim KS, Lee BH, Yoo HW

Objective: The purpose of this study was to investigate the impact of surgical interventions on the survival rate of the trisomy 18 and to provide the clinical information of the...
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Protective Effect of Rice Bran Oil against β-Amyloid Protein-Induced Memory Impairment and Neuronal Death in Mice

Jang JY, Lee HK, Yoo HS, Seong YH

This study was undertaken to investigate the protective effect of rice bran oil (RBO) on amyloid β protein (Aβ) (25-35)-induced memory impairment and brain damage in an ICR mouse model....
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Comparative analysis of serological tests and fecal detection in the diagnosis of Mycobacterium avium subspecies paratuberculosis infection

Park HT, Ha S, Park HE, Shim S, Hur TY, Yoo HS

Abstract: Johne's disease (JD) caused by Mycobacterium avium subspecies paratuberculosis (MAP) is a chronic, wasting infectious disease in ruminants that causes enormous economic losses to the dairy and beef cattle...
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The Key Role of DNA Methylation and Histone Acetylation in Epigenetics of Atherosclerosis

Lee HT, Oh S, Ro DH, Yoo H, Kwon YW

Atherosclerosis, which is the most common chronic disease of the coronary artery, constitutes a vascular pathology induced by inflammation and plaque accumulation within arterial vessel walls. Both DNA methylation and...
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All-Trans Retinoic Acid Synergizes with Enasidenib to Induce Differentiation of IDH2-Mutant Acute Myeloid Leukemia Cells

Kim Y, Jeung HK, Cheong JW, Song J, Bae SH, Lee JI, Min YH

Purpose: Pharmacological inhibition of mutant isocitrate dehydrogenase (IDH) reduces R-2-hydroxyglutarate (2-HG) levels and restores cellular differentiation in vivo and in vitro. The IDH2 inhibitor enasidenib (AG-221) has been approved by...
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Association of Hand Grip Strength and Cardiometabolic Markers in Korean Adult Population: The Korea National Health and Nutrition Examination Survey 2015-2016

Chong H, Choi YE, Kong JY, Park JH, Yoo HJ, Byeon JH, Lee HJ, Lee SH

Background: Muscle strength has been suggested as a cardiovascular marker. The aim of this study was to examine the associations between hand grip strength and biomarkers of cardiovascular disease in...
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Dexamethasone Interferes with Autophagy and Affects Cell Survival in Irradiated Malignant Glioma Cells

Komakech A, Im JH, Gwak HS, Lee KY, Kim JH, Yoo BC, Cheong H, Park JB, Kwon JW, Shin SH, Yoo H

Objective : Radiation is known to induce autophagy in malignant glioma cells whether it is cytocidal or cytoprotective. Dexamethasone is frequently used to reduce tumor-associated brain edema, especially during radiation therapy....
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Higher Lactate Level and Lactate-to-Pyruvate Ratio in Autism Spectrum Disorder

Oh M, Kim SA, Yoo HJ

  • KMID: 2506535
  • Exp Neurobiol.
  • 2020 Aug;29(4):314-322.
  • doi: 10.5607/en20030
Mitochondrial dysfunction is considered one of the pathophysiological mechanisms of autism spectrum disorder (ASD). However, previous studies of biomarkers associated with mitochondrial dysfunction in ASD have revealed inconsistent results. The...
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Dietary Life of Chinese International Students according to the Frequency of University Foodservice Use in Korea

Cui Y, Yoo HJ, Choi I, Yoon J

Objective This study investigated the current use of university foodservice among Chinese international students in Korea, focusing on the relationship between the frequency of university foodservice use and their dietary...
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Treatment of multiple craniofacial osteomas by endoscopic approach

Yoo H, Doh G, Kim BK

Osteomas are benign osteogenic neoplasms that usually occur as solitary craniofacial lesions. Multiple osteomas are rare, particularly those that do not occur as part of an associated syndrome. We report...
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Differential Impact of Cigarette Smoking on Fracture Risks in Subjective Cognitive Decline and Dementia: A Nationwide Longitudinal Study

Um YH, Wang SM, Han Kd, Kim NY, Kang DW, Na HR, Lee CU, Lim HK

Objective We aimed to explore the differential impact of cigarette smoking on fracture risks in SCD and dementia. Methods A nationwide population-based cohort study design was used. Out of all the...
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Clinical Usefulness of Fungal Culture of EBUS-TBNA Needle Rinse Fluid and Core Tissue

Ko RE, Jeong BH, Huh HJ, Lee NY, Yoo H, Jhun BW, Han J, Lee K, Kim H, Kwon OJ, Um SW

Purpose: The diagnosis of pulmonary fungal infections is challenging due to the difficulty of obtaining sufficient specimens. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) needle rinse fluid has become an emerging...
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