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Science Goes On, As Life Does

Yoo HJ

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Adaptations in Anatomy Education during COVID-19

Yoo H, Kim D, Lee YM, Rhyu IJ

Background: The impact of coronavirus disease 2019 (COVID-19) has profoundly affected education, with most universities changing face-to-face classes to online formats. To adapt to the COVID-19 pandemic situation, we adopted...
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Fumonisin B1-Induced Toxicity Was Not Exacerbated in Glutathione Peroxidase-1/Catalase Double Knock Out Mice

Yayeh T, Jeong HR, Park YS, Moon S, Sur B, Yoo HS, Oh S

Fumonisin B1 (FB1) structurally resembles sphingolipids and interferes with their metabolism leading to sphingolipid dysregulation. We questioned if FB1 could exacerbate liver or kidney toxicities in glutathione peroxidase 1 (Gpx1)...
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Surgical Interventions and Clinical Outcomes of Patients with Trisomy 18: a Single Center Experience

Oh MY, Lee BS, Cha T, Jeong J, Jung E, Kim EAR, Kim KS, Lee BH, Yoo HW

Objective: The purpose of this study was to investigate the impact of surgical interventions on the survival rate of the trisomy 18 and to provide the clinical information of the...
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Protective Effect of Rice Bran Oil against β-Amyloid Protein-Induced Memory Impairment and Neuronal Death in Mice

Jang JY, Lee HK, Yoo HS, Seong YH

This study was undertaken to investigate the protective effect of rice bran oil (RBO) on amyloid β protein (Aβ) (25-35)-induced memory impairment and brain damage in an ICR mouse model....
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Comparative analysis of serological tests and fecal detection in the diagnosis of Mycobacterium avium subspecies paratuberculosis infection

Park HT, Ha S, Park HE, Shim S, Hur TY, Yoo HS

Abstract: Johne's disease (JD) caused by Mycobacterium avium subspecies paratuberculosis (MAP) is a chronic, wasting infectious disease in ruminants that causes enormous economic losses to the dairy and beef cattle...
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The Key Role of DNA Methylation and Histone Acetylation in Epigenetics of Atherosclerosis

Lee HT, Oh S, Ro DH, Yoo H, Kwon YW

Atherosclerosis, which is the most common chronic disease of the coronary artery, constitutes a vascular pathology induced by inflammation and plaque accumulation within arterial vessel walls. Both DNA methylation and...
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All-Trans Retinoic Acid Synergizes with Enasidenib to Induce Differentiation of IDH2-Mutant Acute Myeloid Leukemia Cells

Kim Y, Jeung HK, Cheong JW, Song J, Bae SH, Lee JI, Min YH

Purpose: Pharmacological inhibition of mutant isocitrate dehydrogenase (IDH) reduces R-2-hydroxyglutarate (2-HG) levels and restores cellular differentiation in vivo and in vitro. The IDH2 inhibitor enasidenib (AG-221) has been approved by...
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Association of Hand Grip Strength and Cardiometabolic Markers in Korean Adult Population: The Korea National Health and Nutrition Examination Survey 2015-2016

Chong H, Choi YE, Kong JY, Park JH, Yoo HJ, Byeon JH, Lee HJ, Lee SH

Background: Muscle strength has been suggested as a cardiovascular marker. The aim of this study was to examine the associations between hand grip strength and biomarkers of cardiovascular disease in...
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Dexamethasone Interferes with Autophagy and Affects Cell Survival in Irradiated Malignant Glioma Cells

Komakech A, Im JH, Gwak HS, Lee KY, Kim JH, Yoo BC, Cheong H, Park JB, Kwon JW, Shin SH, Yoo H

Objective : Radiation is known to induce autophagy in malignant glioma cells whether it is cytocidal or cytoprotective. Dexamethasone is frequently used to reduce tumor-associated brain edema, especially during radiation therapy....
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Higher Lactate Level and Lactate-to-Pyruvate Ratio in Autism Spectrum Disorder

Oh M, Kim SA, Yoo HJ

  • KMID: 2506535
  • Exp Neurobiol.
  • 2020 Aug;29(4):314-322.
  • doi: 10.5607/en20030
Mitochondrial dysfunction is considered one of the pathophysiological mechanisms of autism spectrum disorder (ASD). However, previous studies of biomarkers associated with mitochondrial dysfunction in ASD have revealed inconsistent results. The...
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Dietary Life of Chinese International Students according to the Frequency of University Foodservice Use in Korea

Cui Y, Yoo HJ, Choi I, Yoon J

Objective This study investigated the current use of university foodservice among Chinese international students in Korea, focusing on the relationship between the frequency of university foodservice use and their dietary...
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Treatment of multiple craniofacial osteomas by endoscopic approach

Yoo H, Doh G, Kim BK

Osteomas are benign osteogenic neoplasms that usually occur as solitary craniofacial lesions. Multiple osteomas are rare, particularly those that do not occur as part of an associated syndrome. We report...
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Differential Impact of Cigarette Smoking on Fracture Risks in Subjective Cognitive Decline and Dementia: A Nationwide Longitudinal Study

Um YH, Wang SM, Han Kd, Kim NY, Kang DW, Na HR, Lee CU, Lim HK

Objective We aimed to explore the differential impact of cigarette smoking on fracture risks in SCD and dementia. Methods A nationwide population-based cohort study design was used. Out of all the...
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Clinical Usefulness of Fungal Culture of EBUS-TBNA Needle Rinse Fluid and Core Tissue

Ko RE, Jeong BH, Huh HJ, Lee NY, Yoo H, Jhun BW, Han J, Lee K, Kim H, Kwon OJ, Um SW

Purpose: The diagnosis of pulmonary fungal infections is challenging due to the difficulty of obtaining sufficient specimens. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) needle rinse fluid has become an emerging...
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Inhibition of Ceramide Accumulation in Podocytes by Myriocin Prevents Diabetic Nephropathy

Woo CY, Baek JY, Kim AR, Hong CH, Yoon JE, Kim HS, Yoo HJ, Park TS, Kc R, Lee KU, Koh EH

Background: Ceramides are associated with metabolic complications including diabetic nephropathy in patients with diabetes. Recent studies have reported that podocytes play a pivotal role in the progression of diabetic nephropathy. Also,...
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Effects of Diabetes Mellitus on the Disposition of Tofacitinib, a Janus Kinase Inhibitor, in Rats

Gwak EH, Yoo HY, Kim SH

Tofacitinib, a Janus kinase inhibitor, was developed for the treatment of rheumatoid arthritis. Recently, it has been associated with an increased change in arthritis development in patients with diabetes. Herein,...
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Age- and Sex-Related Differential Associations between Body Composition and Diabetes Mellitus

Roh E, Hwang SY, Kim JA, Lee YB, Hong Sh, Kim NH, Seo JA, Kim SG, Kim NH, Choi KM, Baik SH, Yoo HJ

Background: The age- and sex-related differences on the impacts of body composition on diabetes mellitus (DM) remain uncertain. Methods: The fourth and fifth Korea National Health and Nutrition Examination Survey included...
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Orexin and Alzheimer’s Disease: A New Perspective

Um YH, Lim HK

Orexin’s role in human cognition has recently been emphasized and emerging evidences indicate its close relationship with Alzheimer’s disease (AD). This review aimed to demonstrate recent research on the relationship...
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RF Heating of Implants in MRI: Electromagnetic Analysis and Solutions

Cho Y, Yoo H

When a patient takes an MRI scan, the patient has a risk of unexpected injuries due to the intensive electromagnetic (EM) field. Among the injuries, the tissue heating by the...
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