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Recent Trends in Creatinine Assays in Korea: LongTerm Accuracy-Based Proficiency Testing Survey Data by the Korean Association of External Quality Assessment Service (2011–2019)

Jeong TD, Cho EJ, Lee K, Lee W, Yun YM, Chun S, Song J, Min WK

Background: Accurate serum creatinine (Cr) concentration measurement is essential for evaluating kidney function. In 2011, the Korean Association of External Quality Assessment Service (KEQAS) launched an accuracy-based Cr proficiency testing...
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Immunosuppressive Drug Measurement by Liquid Chromatography Coupled to Tandem Mass Spectrometry: Interlaboratory Comparison in the Korean Clinical Laboratories

Kim HK, Park HD, Lee SG, Chae H, Song SH, Lee YW, Yun YM, Ahn S, Kim S, Lee SM, Lee SY, Chun S, on behalf of the Clinical Mass Spectrometry Research Committee of the Korean Society of Clinical Chemistry

Background: Liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) is increasingly used for immunosuppressive drug tests. However, most LC-MS/MS tests are laboratory-developed and their agreement is unknown in different Korean...
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Effectiveness of Plasma and Urine Neutrophil Gelatinase-Associated Lipocalin for Predicting Acute Kidney Injury in High-Risk Patients

Yi A, Lee CH, Yun YM, Kim H, Moon HW, Hur M

Background: Neutrophil gelatinase-associated lipocalin (NGAL) is a useful biomarker for acute kidney injury (AKI) prediction. However, studies on whether using both plasma NGAL (PNGAL) and urine NGAL (UNGAL) can improve...
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Serial Assays of QuantiFERON-TB Gold In-Tube and QuantiFERON-TB Gold-Plus in Subjects Exposed to Patients with Active Tuberculosis

Moon HW, Yi A, Yoon S, Kim H, Chung HJ, Hur M, Yun YM, Yoo KH

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Effects of the new diagnosis-related group-based payment system and the increased incentive policy rates on the utilization rate of diagnostic laboratory test in Korea

Lee HR, Kim S, Yun YM, Heo JH, Lee KS, Jeong H, Kwon GC, Um TH, Kim H

A new diagnosis-related group (DRG) based payment system has been implemented in most public hospitals in Korea. We investigated the effects of the new DRG system and its incentive policy...
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A Case of Peritonitis and Disseminated Mucormycosis Caused by Mucor circinelloides in a Patient with Nodal Marginal Zone B-cell Lymphoma

Yoon S, Kim H, Moon HW, Huh HJ, Hur M, Yun YM, Lee MH

Mucormycosis is a fungal infection, which is difficult to treat due to its rapid dissemination and low susceptibility to anti-fungal agents. Peritonitis preceded by gastrointestinal mucormycosis is very rare, and...
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Cereblon Deletion Ameliorates Lipopolysaccharide-induced Proinflammatory Cytokines through 5′-Adenosine Monophosphate-Activated Protein Kinase/Heme Oxygenase-1 Activation in ARPE-19 Cells

Kim YK, Chae SC, Yang HJ, An DE, Lee S, Yeo MG, Lee KJ

Cereblon (CRBN), a negative modulator of AMP-activated protein kinase (AMPK), is highly expressed in the retina. We confirmed the expression of CRBN in ARPE-19 human retinal cells by Western blotting....
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Clinical Utility of Fecal Neutrophil Gelatinase-Associated Lipocalin and Calprotectin as Biomarkers of Clostridioides (Clostridium) difficile Infection

Yi J, Kim H, Moon HW, Hur M, Yun YM

Background Current methods for diagnosing Clostridioides difficile infections (CDIs) fail to provide information on their severity. Fecal neutrophil gelatinase-associated lipocalin (NGAL) and calprotectin are candidate biomarkers for evaluating the severity of...
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Absolute Change in High-Sensitivity Cardiac Troponin I at Three Hours After Presentation is Useful for Diagnosing Acute Myocardial Infarction in the Emergency Department

Kim JW, Kim H, Yun YM, Lee KR, Kim HJ

Background: A rise and/or fall in cardiac troponin value with at least one value above the 99th percentile upper reference limit is essential for acute myocardial infarction (AMI) diagnosis. We...
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Performance Evaluation of the QXDx BCR-ABL %IS Droplet Digital PCR Assay

Chung HJ, Hur M, Yoon S, Hwang K, Lim HS, Kim H, Moon HW, Yun YM

Accurate detection of BCR-ABL fusion transcripts at and below molecular response (MR) 4 (0.01% International Scale [IS]) is required for disease monitoring in patients with chronic myeloid leukemia (CML). We...
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Report of Korean Association of External Quality Assessment Service on the Accuracy-Based Lipid Proficiency Testing (2016–2018)

Kim JH, Cho Y, Lee SG, Yun YM

The accuracy-based lipid (ABL) proficiency testing (PT) program was started in 2016 by the Korean External Quality Assessment Service to minimize the matrix effect. We analyzed 3 years of the...
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In-Hospital and Post-Discharge Recovery after Acute Ischemic Stroke: a Nationwide Multicenter Stroke Registry-base Study

Jang MU, Kang J, Kim BJ, Hong JH, Yeo MJ, Han MK, Lee BC, Yu KH, Oh MS, Choi KC, Lee SH, Hong KS, Cho YJ, Park JM, Cha JK, Kim DH, Park TH, Lee KB, Lee SJ, Lee J, Kim JT, Kim DE, Choi JC, Lee J, Lee JS, Gorelick P, Bae HJ

BACKGROUND: Using data from a large national stroke registry, we aimed to investigate the incidence and determinants of in-hospital and post-discharge recovery after acute ischemic stroke and the independence of...
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Use of Liquid Chromatography-Tandem Mass Spectrometry for Clinical Testing in Korean Laboratories: a Questionnaire Survey

Chae H, Cho SE, Park HD, Chun S, Lee YW, Yun YM, Song SH, Lee SG, Lee K, Song J, Lee SY, On behalf of the Clinical Mass Spectrometry Research Committee of Korean Society of Clinical Chemistry

BACKGROUND: The use of liquid chromatography-tandem mass spectrometry (LC-MS/MS) has substantially increased in clinical laboratories worldwide. To assess the status of clinical LC-MS/MS testing in Korean laboratories, a questionnaire survey...
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Preparation and Characterization of Human Adipose Tissue-Derived Extracellular Matrix, Growth Factors, and Stem Cells: A Concise Review

Chun SY, Lim JO, Lee EH, Han MH, Ha YS, Lee JN, Kim BS, Park MJ, Yeo M, Jung B, Kwon TG

BACKGROUND: Human adipose tissue is routinely discarded as medical waste. However, this tissue may have valuable clinical applications since methods have been devised to effectively isolate adipose-derived extracellular matrix (ECM),...
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A Questionnaire Survey on General Status and Opinions about Clinical Mass Spectrometric Analysis in Korea (2018)

Cho SE, Chae H, Park HD, Chun S, Lee YW, Yun YM, Song SH, Lee SG, Lee K, Song J, Lee SY, On behalf of the Clinical Mass Spectrometry Research Committee of Korean Society of Clinical Chemistry

The Clinical Mass Spectrometry Research Committee (CMSRC), in affiliation with the Korean Society of Clinical Chemistry (KSCC), conducted a questionnaire survey on opinions about the general status of clinical mass...
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First Case in Korea of Group B Streptococcus With Reduced Penicillin Susceptibility Harboring Amino Acid Substitutions in Penicillin-Binding Protein 2X

Yi A, Kim CK, Kimura K, Arakawa Y, Hur M, Yun YM, Moon HW

No abstract available.
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The Epidemiology of Fracture in Patients with Acute Ischemic Stroke in Korea

Lee KB, Lee JG, Kim BJ, Kim JY, Lee KJ, Han MK, Park JM, Kang K, Cho YJ, Park HK, Hong KS, Park TH, Lee SJ, Oh MS, Yu KH, Lee BC, Cha JK, Kim DH, Kim JT, Lee J, Hong JH, Sohn SI, Kim DE, Choi JC, Yeo MJ, Kim WJ, Chae JE, Lee JS, Lee J, Bae HJ, on behalf of the CRCS-K investigators

BACKGROUND: Patients who survive an acute phase of stroke are at risk of falls and fractures afterwards. However, it is largely unknown how frequent fractures occur in the Asian stroke...
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Accuracy-Based Proficiency Testing of Creatinine Measurement: 7 Years' Experience in Korea

Jeong TD, Lee HA, Lee K, Yun YM

BACKGROUND: Standardization of creatinine assay is consistently performed and much effort has been put into improving the accuracy of the results. We aimed to analyze the results of accuracy-based proficiency...
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Peritoneal Fluid Cytology of Disseminated Large Cell Neuroendocrine Carcinoma Combined with Endometrioid Adenocarcinoma of the Endometrium

Lee YM, Yeo MK, Choi SY, Kim KH, Suh KS

No abstract available.
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Concurrent Anti-glomerular Basement Membrane Nephritis and IgA Nephropathy

Suh KS, Choi SY, Bae GE, Choi DE, Yeo MK

Anti–glomerular basement membrane (GBM) nephritis is characterized by circulating anti-GBM antibodies and crescentic glomerulonephritis (GN) with deposition of IgG along the GBM. In a limited number of cases, glomerular immune...
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