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Expressions of miRNAs in Papillary Thyroid Carcinoma and Their Associations with the BRAFV600EMutation and Clinicopathological Features.

Yang SI, Choi YS

Objectives: The microRNAs (miRNAs) are known to be commonly expressed in papillary thyroid carcinoma. The BRAFV600Emutation is the most common genetic mutation in thyroid cancer. The main aim of this...
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Imbalance of Gut Streptococcus, Clostridium, and Akkermansia Determines the Natural Course of Atopic Dermatitis in Infant

Park YM, Lee SY, Kang MJ, Kim BS, Lee MJ, Jung SS, Yoon JS, Cho HJ, Lee E, Yang SI, Seo JH, Kim HB, Suh DI, Shin YH, Kim KW, Ahn K, Hong SJ

PURPOSE: The roles of gut microbiota on the natural course of atopic dermatitis (AD) are not yet fully understood. We investigated whether the composition and function of gut microbiota and...
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Risk Factors and Comorbidities Associated With the Allergic Rhinitis Phenotype in Children According to the ARIA Classification

Jung S, Lee SY, Yoon J, Cho HJ, Kim YH, Suh DI, Yang SI, Kwon JW, Jang GC, Sun YH, Woo SI, Youn YS, Park KS, Lee E, Cho HJ, Kook MH, Yi HR, Chung HL, Kim JH, Kim HY, Jung JA, Woo HO, Lee JK, Chang WS, Do NH, Cho H, Hong SJ

PURPOSE: Data are lacking on the association between the allergic rhinitis (AR) phenotype and sensitization to specific allergens or bronchial hyperresponsiveness (BHR) in children. We here investigated risk factors and...
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Epidural Abscess Caused by Eikenella corrodens in a Previously Healthy Child

Kim YK, Han MS, Yang SI, Yun KW, Han DH, Kim JY, Choi EH

Eikenella corrodens rarely causes invasive head and neck infections in immunocompetent children. We report a case of epidural abscess caused by E. corrodens in a previously healthy 13-year-old boy who...
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Evaluation of a Rapid Diagnostic Antigen Test Kit Ribotest Mycoplasma® for the Detection of Mycoplasma pneumoniae

Yang SI, Han MS, Kim SJ, Lee SY, Choi EH

PURPOSE: Early detection of Mycoplasma pneumoniae is important for appropriate antimicrobial therapy in children with pneumonia. This study aimed to evaluate the diagnostic value of a rapid antigen test kit...
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Indoor pet ownership in infancy is a risk factor for the development of sensitization to pets and asthma in childhood

Jung S, Noh SR, Lee SY, Yoon J, Cho HJ, Kim YH, Suh DI, Yang SI, Kwon JW, Jang GC, Sun YH, Woo SI, Youn YS, Park KS, Lee E, Cho HJ, Kook MH, Yi HR, Chung HL, Kim JH, Kim HY, Jung JA, Woo HO, Hong SJ

PURPOSE: It is controversial whether indoor pet exposure is either a risk or protective factor developing sensitization to pet allergens or asthma. Therefore, we investigated whether indoor pet ownership entails...
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Particulate matter and childhood allergic diseases

Yang SI

Particulate matter (PM) is a ubiquitous air pollutant that is a growing public health concern. Previous studies have suggested that PM is associated with asthma development and exacerbation of asthma...
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Prevalence, Risk Factors and Cutoff Values for Bronchial Hyperresponsiveness to Provocholine in 7-Year-Old Children

Jung S, Suh DI, Lee SY, Yoon J, Cho HJ, Kim YH, Yang SI, Kwon JW, Jang GC, Sun YH, Woo SI, Youn YS, Park KS, Cho HJ, Kook MH, Yi HR, Chung HL, Kim JH, Kim HY, Jung JA, Woo HO, Hong SJ

BACKGROUND: A US Food and Drug Administration (FDA)-approved drug methacholine chloride (Provocholine®) was recently introduced to Korea where it is now widely used in clinical practice. We aimed to evaluate...
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Case of Raynaud Syndrome after the Use of Methimazole

Kim Y, Tag HS, Kim GT, Lee SG, Park EK, Park JH, Kweon SM, Yang SI, Kim JH

Raynaud syndrome is a medical condition that causes pain, numbness, and changes in skin color at the distal extremities. Raynaud syndrome can be subdivided into primary Raynaud's and secondary Raynaud's....
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Two Cases of Chloromethylisothiazolinone and Methylisothiazolinone-associated Toxic Lung Injury

Lee E, Son SK, Yoon J, Cho HJ, Yang SI, Jung S, Do KH, Cho YA, Lee SY, Park DU, Hong SJ

Previous animal studies have not conclusively determined the association between exposure to humidifier disinfectants (HDs) containing 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT) and/or 2-methyl-4-isothiazolin-3-one (MIT) and development of HD-associated lung injuries. Nonetheless, patients exposed...
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Blackwater Fever Followed by Severe Falciparum Malaria in a Child

Yang SI, Choe YJ, Lee HJ, Choi EH

Blackwater fever is a serious clinical syndrome manifested by acute intravascular hemolysis, fever, and the passage of black or red urine, which is classically associated with falciparum malaria and irregular...
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Allergic Rhinitis in Preschool Children and the Clinical Utility of FeNO

Yoon J, Choi YJ, Lee E, Cho HJ, Yang SI, Kim YH, Jung YH, Seo JH, Kwon JW, Kim HB, Lee SY, Kim BS, Shim JY, Kim EJ, Lee JS, Hong SJ

PURPOSE: The nature of allergic rhinitis (AR) in preschool aged children remains incompletely characterized. This study aimed to investigate the prevalence of AR and its associated risk factors in preschool-aged...
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Antibiotic Resistance Patterns and Serotypes of Salmonella spp. Isolated at Jeollanam-do in Korea

Yoon KB, Song BJ, Shin MY, Lim HC, Yoon YH, Jeon DY, Ha H, Yang SI, Kim JB

OBJECTIVES: Few long-term studies have been conducted on the serotype and antibiotic resistance patterns of Salmonella speices (spp.) The aim of this study was to determine the serotypes and antibiotic...
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Prenatal Maternal Distress and Allergic Diseases in Offspring: Review of Evidence and Possible Pathways

Suh DI, Chang HY, Lee E, Yang SI, Hong SJ

Recent studies have suggested a close association between prenatal maternal distress and allergic diseases in the offspring. We selected relevant birth-cohort or national registry studies using a keyword search of...
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The First Successful Lung Transplantation in a Korean Child with Cystic Fibrosis

Noh SR, Lee E, Yoon J, Jung S, Yang SI, Yu J, Hong SJ

Cystic fibrosis (CF) is an autosomal recessive inherited multisystem disorder caused by mutations of the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Respiratory failure remains the most...
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Primary Sclerosing Mucoepidermoid Carcinoma with Eosinophilia of the Thyroid: Description of a Case and Review of the Literature

Yang SI, Park KK, Yoo JY

Primary sclerosing mucoepidermoid carcinoma with eosinophilia (SMECE) of the thyroid gland is a very rare disease. We present the clinical and histopathologic findings of a 37-year-old woman recently diagnosed with...
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Food allergic reactions in the community: a questionnaire survey of caregivers

Seo AD, Lee JY, Yang SI, Lee HR, Lee SY

PURPOSE: Food allergies are adverse immune reactions to food. Despite their importance, there have only been a few studies conducted on situations that may cause food allergies in Korean children....
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Dynamics of Gut Microbiota According to the Delivery Mode in Healthy Korean Infants

Lee E, Kim BJ, Kang MJ, Choi KY, Cho HJ, Kim Y, Yang SI, Jung YH, Kim HY, Seo JH, Kwon JW, Kim HB, Lee SY, Hong SJ

Microbial colonization of the infant gut is unstable and shows a wide range of diversity between individuals. Gut microbiota play an important role in the development of the immune system,...
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The change in food allergy prevalence of elementary school children in Seoul since the last 20 years and the risk factor analysis

Kim YH, Lee SY, Lee E, Cho HJ, Kim HB, Kwon JW, Yang SI, Kim EJ, Lee JK, Hong SJ

PURPOSE: There are many reports that the prevalence of food allergy (FA) is globally increasing. We investigated the change in FA prevalence since the last 20 years in elementary school...
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The First Successful Heart-Lung Transplant in a Korean Child with Humidifier Disinfectant-Associated Interstitial Lung Disease

Jhang WK, Park SJ, Lee E, Yang SI, Hong SJ, Seo JH, Kim HY, Park JJ, Yun TJ, Kim HR, Kim YH, Kim DK, Park SI, Lee SO, Hong SB, Shim TS, Choi IC, Yu J

From 2006 to 2011, an outbreak of a particular type of childhood interstitial lung disease occurred in Korea. The condition was intractable and progressed to severe respiratory failure, with a...
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