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Predicting Imaging Remission in Rheumatoid Arthritis: a Case-control Ultrasound Study

Chung SW, Choi JY, Lee SH, Song R, Yang HI, Hong SJ, Lee YA

Background: To elucidate the achievement rates of imaging remission and to examine the characteristics associated with imaging remission status among patients with rheumatoid arthritis (RA) who have attained clinical remission. Methods:...
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Comparing Effectiveness Rituximab (Mabthera®) to Other Second-line Biologics for Rheumatoid Arthritis Treatment in Patients Refractory to or Intolerant of First-line Anti-tumor Necrosis Factor Agent: An Observational Study

Park YW, Kim KJ, Yang HI, Yoon BY, Kim SH, Kim SH, Kim J, Oh JS, Kim WU, Lee YA, Choe JY, Park MC, Lee SH

OBJECTIVE: Failure of first-line anti-tumor necrosis factor (TNF) agents in in rheumatoid arthritis patients leads to decisions among second-line biologic agents. To better inform these decisions, the therapeutic effectiveness of...
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Hypocomplementemic Urticarial Vasculitis Syndrome with Membranous Nephropathy: Case Report

Jung SW, Choi YY, Choi IS, Kim S, Jeong KH, Song R, Lee SH, Yang HI, Hong SJ, Lee YA

Urticarial vasculitis is a rare disorder that principally manifests with recurrent urticarial, sometimes hemorrhagic, skin lesions and/or angioedema. Its clinical presentation is not always limited to cutaneous lesions and it...
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A Case of Palmoplantar Pustulosis Present in the Daughter of a SAPHO Syndrome Patient

Choi JY, Kim JM, Song R, Lee YA, Lee SH, Yang HI, Hong SJ

SAPHO syndrome is a rare inflammatory, pseudoinfectious disease. Initially it was an acronym for Syndrome Acne Pustulosis Hyperostosis Osteitis, and the meaning of S was later changed to synovitis. It...
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The role of adiponectin in the production of IL-6, IL-8, VEGF and MMPs in human endothelial cells and osteoblasts: implications for arthritic joints

Lee YA, Ji HI, Lee SH, Hong SJ, Yang HI, Chul Yoo M, Kim KS

This study was performed to evaluate the contribution of adiponectin to the production of interleukin (IL)-6, IL-8, vascular endothelial growth factor (VEGF), matrix metalloproteinase (MMP)-1 and MMP-13 in human endothelial...
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A Case of Overlap Syndrome of Rheumatoid Arthritis and Polymyositis with the Involvement of Upper Pharyngeal Muscles

Jang WS, Kim SM, Hong SJ, Lee SH, Song R, Yang HI, Lee YA

An overlap syndrome is a combination of major features of more than one connective tissue diseases which is presented in the same patient. An overlap syndrome of rheumatoid arthritis (RA)...
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A Case of Myotonic Dystrophy with Electrolyte Imbalance

Ko WJ, Kim KY, Kim SM, Hong SJ, Lee SH, Song R, Yang HI, Lee YA

Type 1 myotonic dystrophy (DM1) is an autosomal-dominant inherited disorder with a multisystem involvement, caused by an abnormal expansion of the CTG sequence of the dystrophic myotonia protein kinase (DMPK)...
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Histopathological Evaluation of Heart Toxicity of a Novel Selective PPAR-gamma Agonists CKD-501 in db/db Mice

Yang HI, Kim WS, Kim DH, Kang JS

  • KMID: 2170691
  • Biomol Ther.
  • 2013 Jan;21(1):84-88.
High risk of cardiovascular diseases caused by existing PPAR-gamma agonists such as rosiglitazone and pioglitazone has been recently reported. CKD-501 is a novel selective PPAR-gamma agonist as a potential target...
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Imatinib Mesylate is Effective for Patients Not Only with Chronic Myeloid Leukemia, but Also Rheumatoid Arthritis

Jung HJ, Kim DH, Song R, Hong SJ, Yang HI, Eo WK, Lee SH

  • KMID: 2263467
  • Korean J Med.
  • 2012 Sep;83(3):405-410.
Synovial tissue proliferation and inflammation are regarded as possible causes of rheumatoid arthritis. Activation of tyrosine kinase by numerous cytokines and BCR-ABL translocation contribute to synovial tissue inflammation and the...
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A Case of Development of Vitiligo Followed by TNF-alpha Antagonist Treatment for Rheumatoid Arthritis

Song R, Kim SM, Lee SH, Lee YA, Hong SJ, Cho HR, Kim GY, Yang HI

As the usage of biologics for rheumatic diseases increases, such as rheumatoid arthritis and ankylosing spondylitis, various cutaneous adverse events are also being increasingly reported. We experienced a case of...
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Synergy between adiponectin and interleukin-1beta on the expression of interleukin-6, interleukin-8, and cyclooxygenase-2 in fibroblast-like synoviocytes

Lee YA, Choi HM, Lee SH, Yang HI, Yoo MC, Hong SJ, Kim KS

  • KMID: 1397448
  • Exp Mol Med.
  • 2012 Jul;44(7):440-447.
To determine whether adiponectin may have synergistic effects in combination with the proinflammatory cytokine interleukin (IL)-1beta regarding the production of proinflammatory mediators during arthritic joint inflammation, synovial cells from rheumatoid...
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Results of laparoscopic davydov technique in 47 patients with congenital absence of the vagina: laparoscopic peritoneal vaginoplasty

Park KH, Park JH, Yang HI, Choi BR, Baek JH, Hong Y, Cho S, Seo SK, Choi YS, Lee BS

OBJECTIVE: To evaluate the technical feasibility and anatomical and functional outcomes of laparoscopic Davydov technique (transvestibular vaginoplasty with pelvic peritoneum) for the patients with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome. METHODS: This study was...
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A Case of Behcet's Disease Associated with Myelofibrosis

Kim JW, Lee SH, Song R, Lee YA, Hong SJ, Yang HI

Behcet's disease (BD) is a systemic vasculitis of unknown etiology that is rarely observed in association with leukemia and other hematologic disorders. We recently encountered a patient who presented with...
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Taurine ameliorates hyperglycemia and dyslipidemia by reducing insulin resistance and leptin level in Otsuka Long-Evans Tokushima fatty (OLETF) rats with long-term diabetes

Kim KS, Oh DH, Kim JY, Lee BG, You JS, Chang KJ, Chung H, Yoo MC, Yang HI, Kang JH, Hwang YC, Ahn KJ, Chung HY, Jeong IK

  • KMID: 1401758
  • Exp Mol Med.
  • 2012 Nov;44(11):665-673.
This study aimed to determine whether taurine supplementation improves metabolic disturbances and diabetic complications in an animal model for type 2 diabetes. We investigated whether taurine has therapeutic effects on...
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White blood cell differential count and adnexal mass size may predict potential malignancies in laparoscopic surgery

Choi BR, Hong Y, Baek JH, Huh JS, Jang MY, Jeun YE, Lee KE, Lim KJ, Yang HI, Choi YS, Kim HY, Seo SK, Cho S, Lee BS

  • KMID: 2083903
  • Korean J Gynecol Endosc Minim Invasive Surg.
  • 2011 May;23(1):32-39.
OBJECTIVE: We investigated the clinical value of using preoperative differential white blood cell (WBC) count to predict the potential for malignancy of adnexal masses in laparoscopic surgery. METHODS: The electronic medical...
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Comparison of Factors Which Influence the Brachial-Ankle Pulse Wave Velocity in Pre- and Postmenopausal Women

Chung CK, Yun BH, Seo SK, Lim KJ, Jeon YE, Yang HI, Lee KE, Cho S, Choi YS, Lee BS

  • KMID: 2321378
  • J Korean Soc Menopause.
  • 2010 Aug;16(2):86-92.
OBJECTIVES: The aim of this study was to compare the factors which influence the brachial-ankle pulse wave velocity (baPWV) in pre- and post-menopausal women. We also investigated the association of...
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Clinical Efficacy of Clomiphene Citrate and Letrozole Combined with Gonadotropins for Superovulation in Patients with Clomiphene-Induced Thin Endometrium

Lee EJ, Park HJ, Yang HI, Lee KE, Seo SK, Kim HY, Cho S, Choi YS, Lee BS, Park KH, Cho DJ

  • KMID: 2070991
  • Korean J Reprod Med.
  • 2009 Jun;36(2):111-119.
OBJECTIVE: The aim of this study was to compare the clinical efficacy of clomiphene citrate (CC) and letrozole combined with gonadotropins for controlled ovarian stimulation (COS) in patients with CC-induced...
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A case of relapsing polychondritis and pyoderma gangrenosum in a patient with Down's syndrome

Cho YD, Lee YA, Park JN, Lee SH, Yang HI, Hong SJ

  • KMID: 2257634
  • Korean J Med.
  • 2009 May;76(5):632-636.
Relapsing polychondritis (RP) is a rare multisystem disorder of unknown etiology that affects cartilaginous tissues, such as the auricular, nasal, and laryngotracheal cartilages. It may be accompanied by a wide...
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Prognostic factors for predicting spontaneous pregnancy after laparoscopic surgical treatment of endometriosis

Jeon YE, Cho S, Lee KE, Yang HI, Seo SK, Kim HY, Choi YS, Lee BS

  • KMID: 2273819
  • Korean J Obstet Gynecol.
  • 2009 Dec;52(12):1287-1295.
OBJECTIVE: To identify the prognostic factors for predicting spontaneous pregnancy after laparoscopic surgical treatment of endometriosis. METHODS: Retrospective analysis was performed in 82 patients who underwent elective laparoscopic surgery with subsequent...
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A Long-Term Treatment Outcome of Abdominal Sacrocolpopexy

Jeon MJ, Moon YJ, Jung HJ, Lim KJ, Yang HI, Kim SK, Bai SW

PURPOSE: The aim of this study was to evaluate the long-term treatment outcome and major complication rates of abdominal sacrocolpopexy (ASC). MATERIALS AND METHODS: This retrospective study included 57 Korean women...
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