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Role of concurrent chemoradiation on locally advanced unresectable adenoid cystic carcinoma

Ha H, Keam B, Ock CY, Kim TM, Kim JH, Chung EJ, Kwon SK, Ahn SH, Wu HG, Sung MW, Heo DS

Background/Aims Adenoid cystic carcinoma (ACC) is a rare salivary gland tumor characterized by indolence, with a high rate of local recurrence and distant metastasis. This study aimed to investigate the effect...
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Carbon Ion Therapy: A Review of an Advanced Technology

Kim Ji, Park JM, Wu HG

This paper provides a brief review of the advanced technologies for carbon ion radiotherapy (CIRT), with a focus on current developments. Compared to photon beam therapy, treatment using heavy ions,...
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Failure patterns of cervical lymph nodes in metastases of unknown origin according to target volume

Kim DY, Heo DS, Keam B, Ock CY, Ahn SH, Kim Jh, Jung KC, Kim JH, Wu HG

Purpose: This study was aim to evaluate the patterns of failure according to radiotherapy (RT) target volume for cervical lymph nodes in metastases of unknown primary origin in head and...
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Dummy Run of Quality Assurance Program before Prospective Study of Hippocampus-Sparing Whole-Brain Radiotherapy and Simultaneous Integrated Boost for Multiple Brain Metastases from Non-small Cell Lung Cancer: Korean Radiation Oncology Group (KROG) 17-06 Study

Chung E, Noh JM, Lee KC, Kim JH, Chung WK, Suh YG, Lee JA, Seol KH, Wu HG, Kim YS, Noh OK, Park JW, Lee DS, Lee J, Kim YS, Park WY, Kang MK, Jo S, Ahn YC

PURPOSE: Lung Cancer Subcommittee of Korean Radiation Oncology Group (KROG) has recently launched a prospective clinical trial (KROG 17-06) of hippocampus-sparing whole brain radiotherapy (HS-WBRT) with simultaneous integrated boost (SIB)...
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Poor prognostic factors in human papillomavirus-positive head and neck cancer: who might not be candidates for de-escalation treatment?

Yoo SH, Ock CY, Keam B, Park SJ, Kim TM, Kim JH, Jeon YK, Chung EJ, Kwon SK, Hah JH, Kwon TK, Jung KC, Kim DW, Wu HG, Sung MW, Heo DS

BACKGROUND/AIMS: Since patients with human papillomavirus (HPV)-associated head and neck squamous cell carcinoma (HNSCC) have favorable outcomes after treatment, treatment de-escalation for these patients is being actively investigated. However, not...
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The Feasibility of Spinal Stereotactic Radiosurgery for Spinal Metastasis with Epidural Cord Compression

Kim YJ, Kim JH, Kim K, Kim HJ, Chie EK, Shin KH, Wu HG, Kim IH

PURPOSE: The purpose of this study was to investigate the effectiveness and safety of spinal stereotactic radiosurgery (SRS) in treating spinal metastasis with epidural spinal cord compression (ESCC). MATERIALS AND METHODS:...
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The Prognostic Value of Albumin-to-Alkaline Phosphatase Ratio before Radical Radiotherapy in Patients with Non-metastatic Nasopharyngeal Carcinoma: A Propensity Score Matching Analysis

Kim JS, Keam B, Heo DS, Han DH, Rhee CS, Kim JH, Jung KC, Wu HG

PURPOSE: We first analyzed the prognostic power of albumin-to-alkaline phosphatase ratio (AAPR) before radical radiotherapy (RT) in non-metastatic nasopharyngeal carcinoma (NPC) patients. MATERIALS AND METHODS: The records of 170 patients with...
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The Effect of Hospital Case Volume on Clinical Outcomes in Patients with Nasopharyngeal Carcinoma: A Multi-institutional Retrospective Analysis (KROG-1106)

Ha B, Cho KH, Moon SH, Lee CG, Keum KC, Kim YS, Wu HG, Kim JH, Ahn YC, Oh D, Noh JM, Lee JH, Kim SH, Kim WT, Oh YT, Kang MK, Kim JH, Kim JY, Cho MJ, Kay CS, Choi JH

PURPOSE: The purpose of this study was to investigate the effect of hospital case volume on clinical outcomes in patients with nasopharyngeal carcinoma (NPC). MATERIALS AND METHODS: Data on 1,073 patients...
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Optimal timing for salvage surgery after definitive radiotherapy in hypopharyngeal cancer

Chun SJ, Keam B, Heo DS, Kim KH, Sung MW, Chung EJ, Kim JH, Jung KC, Kim JH, Wu HG

PURPOSE: Use of radiotherapy combined with chemotherapy is increasing in hypopharyngeal cancer. However, many show residual tumor after radiotherapy. Timing for treatment evaluation and salvage therapy is essential. However, optimal...
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Gamma Evaluation with Portal Dosimetry for Volumetric Modulated Arc Therapy and Intensity-Modulated Radiation Therapy

Kim JI, Choi CH, Park SY, An H, Wu HG, Park JM

The aim of this study is to investigate the characteristics of portal dosimetry in comparison with the MapCHECK2 measurments. In this study, a total of 65 treatment plans including both...
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Implementation of AAPM's TG-51 Protocol on Co-60 MRI-Guided Radiation Therapy System

Cho JD, Park JM, Choi CH, Kim JI, Wu HG, Park SY

For the ViewRay® system (ViewRay Inc., Cleveland, OH, USA) which is representative of magnetic resonance (MR) guided radiotherapy machine, it is important to evaluate effectiveness of AAPM's TG-51 protocol and...
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Comparison of the Clinical Outcomes of Patients with Squamous Cell Carcinoma of the Tonsil Receiving Postoperative Ipsilateral Versus Bilateral Neck Radiotherapy: A Propensity Score Matching Analysis (KROG 11-07)

Kim Y, Cho KH, Moon SH, Lee CG, Keum KC, Lee SW, Ahn YC, Oh D, Kim YS, Won YK, Wu HG, Hah JH, Oh YT

PURPOSE: The impact of postoperative ipsilateral neck radiotherapy (INRT) versus bilateral neck radiotherapy (BNRT) on the clinical outcomes of patients with tonsillar squamous cell carcinoma was analyzed retrospectively. MATERIALS AND METHODS:...
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Treatment Plan Delivery Accuracy of the ViewRay System in Two-Headed Mode

Park JM, Park SY, Wu HG, Kim JI

The aim of this study is to investigate the delivery accuracy of intensity-modulated radiation therapy (IMRT) plans in the two-headed mode of the ViewRayâ„¢ system in comparison with that of...
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The Role of Neoadjuvant Chemotherapy in the Treatment of Nasopharyngeal Carcinoma: A Multi-institutional Retrospective Study (KROG 11-06) Using Propensity Score Matching Analysis

Song JH, Wu HG, Keam BS, Hah JH, Ahn YC, Oh D, Noh JM, Park HJ, Lee CG, Keum KC, Cha J, Cho KH, Moon SH, Kim JY, Chung WK, Oh YT, Kim WT, Cho MJ, Kay CS, Kim YS

PURPOSE: We compared the treatment results and toxicity in nasopharyngeal carcinoma (NPC) patients treated with concurrent chemotherapy (CCRT) alone (the CRT arm) or neoadjuvant chemotherapy followed by CCRT (the NCT...
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Induction chemotherapy in head and neck squamous cell carcinoma of the paranasal sinus and nasal cavity: a role in organ preservation

Ock CY, Keam B, Kim TM, Han DH, Won TB, Lee SH, Hah JH, Kwon TK, Kim DW, Kim DY, Rhee CS, Wu HG, Sung MW, Heo DS

BACKGROUND/AIMS: The role of induction chemotherapy (IC) for eyeball preservation has not been established in head and neck squamous cell carcinoma (HNSCC) of the paranasal sinus and nasal cavity (PNSNC)....
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The Effect of Chemoradiotherapy with SRC Tyrosine Kinase Inhibitor, PP2 and Temozolomide on Malignant Glioma Cells In Vitro and In Vivo

Eom KY, Cho BJ, Choi EJ, Kim JH, Chie EK, Wu HG, Kim IH, Paek SH, Kim JS, Kim IA

PURPOSE: We investigated the effect of chemoradiotherapy with PP2 and temozolomide (TMZ) on malignant glioma cells using clonogenic assays and in vivo brain tumor model. MATERIALS AND METHODS: The effect of...
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Effect of Mesenchymal Stem Cells and Platelet-Derived Growth Factor on the Healing of Radiation Induced Ulcer in Rats

Jin IG, Kim JH, Wu HG, Hwang SJ

Radiation-induced skin ulceration is a frequent complication of radiation therapy. This study investigated the effects of rat mesenchymal stem cells (rMSCs) and platelet-derived growth factor (PDGF) on the healing of...
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ERRATUM: Role of Chemotherapy in Stage II Nasopharyngeal Carcinoma Treated with Curative Radiotherapy

Kang MK, Oh D, Cho KH, Moon SH, Wu HG, Heo DS, Ahn YC, Park K, Park HJ, Park JS, Keum KC, Cha J, Kim JW, Kim YS, Kang JH, Oh YT, Kim JY, Kim SH, Kim JH, Lee CG

In this article, an protocol number error was found in the last paragraph of the introduction part, page 872.
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Patterns of care for patients with nasopharyngeal carcinoma (KROG 11-06) in South Korea

Sung SY, Kang MK, Kay CS, Keum KC, Kim SH, Kim YS, Kim WT, Kim JY, Kim JH, Moon SH, Ahn YC, Oh YT, Wu HG, Lee CG, Chung WK, Cho KH, Cho MJ, Choi JH

PURPOSE: To investigate the patterns of care for patients with nasopharyngeal carcinoma (NPC) in South Korea. MATERIALS AND METHODS: A multi-institutional retrospective study was performed (Korean Radiation Oncology Group [KROG] 11-06)...
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Locoregionally advanced nasopharyngeal carcinoma treated with intensity-modulated radiotherapy plus concurrent weekly cisplatin with or without neoadjuvant chemotherapy

Wee CW, Keam B, Heo DS, Sung MW, Won TB, Wu HG

PURPOSE: The outcomes of locoregionally advanced nasopharyngeal carcinoma patients treated with concurrent chemoradiation (CCRT) using intensity-modulated radiotherapy (IMRT) with/without neoadjuvant chemotherapy (NCT) were evaluated. MATERIALS AND METHODS: Eighty-three patients who underwent...
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