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Recent Advances of Therapeutic Targets for the Treatment of Periodontal Disease

Kim WJ, Soh Y, Heo SM

Periodontal disease is primarily associated with bacterial infection such as dental plaque. Dental plaque, an oral biofilm harboring a complex microbial community, can cause various inflammatory reactions in periodontal tissue....
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Effect of desmopressin lyophilisate (MELT) plus anticholinergics combination on functional bladder capacity and therapeutic outcome as the first-line treatment for primary monosymptomatic nocturnal enuresis: A randomized clinical trial

Shim M, Bang WJ, Oh CY, Kang MJ, Cho JS

Purpose: To assess the efficacy of desmopressin plus anticholinergic combination therapy as first-line treatment for children with primary monosymptomatic nocturnal enuresis (PMNE) and to analyze this combination’s effect on functional...
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CORRIGENDUM: Diagnostic model for pancreatic cancer using a multi-biomarker panel

Choi YJ, Yoon W, Lee A, Han Y, Byun Y, Kang JS, Kim H, Kwon W, Suh YA, Kim Y, Lee S, Namkung J, Han S, Choi Y, Heo JS, Park JO, Park JK, Kim SC, Kang CM, Lee WJ, Park T, Jang JY

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Beneficial effects of proximal intestinal bypass reconstruction on glucose metabolism in a type 2 diabetes animal model: a possible reconstruction strategy for diabetic gastric cancer patients

Ahn SM, Hyung WJ

Purpose: Proximal intestinal bypass (PIB), such as Billroth II or Roux-en-Y gastrojejunostomy after curative distal gastrectomy for gastric cancer induces beneficial effects on glycemic control in patients with type 2...
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Diagnostic model for pancreatic cancer using a multi-biomarker panel

Choi YJ, Yoon W, Lee A, Han Y, Byun Y, Kang JS, Kim H, Kwon W, Suh YA, Kim Y, Lee S, Namkung J, Han S, Choi Y, Heo JS, Park JO, Park JK, Kim SC, Kang CM, Lee WJ, Park T, Jang JY

Purpose: Diagnostic biomarkers of pancreatic ductal adenocarcinoma (PDAC) have been used for early detection to reduce its dismal survival rate. However, clinically feasible biomarkers are still rare. Therefore, in this...
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Feline adipose tissue-derived mesenchymal stem cells pretreated with IFN-γ enhance immunomodulatory effects through the PGE 2 pathway

Park SG, An JH, Li Q, Chae HK, Park SM, Lee JH, Ahn JO, Song WJ, Youn HY

Background: Preconditioning with inflammatory stimuli is used to improve the secretion of anti-inflammatory agents in stem cells from variant species such as mouse, human, and dog. However, there are only...
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Systematic Target Screening Revealed That Tif302 Could Be an OffTarget of the Antifungal Terbinafine in Fission Yeast

Lee S, Nam M, Lee AR, Lee J, Woo J, Kang NS, Balupuri A, Lee M, Kim SY, Ro H, Choi YW, Kim DU, Hoe KL

We used a heterozygous gene deletion library of fission yeasts comprising all essential and non-essential genes for a microarray screening of target genes of the antifungal terbinafine, which inhibits ergosterol...
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High-Sensitivity Troponin I Assay for Differential Diagnosis of New-Onset Myocardial Infarction in Patients with Acute Decompensated Heart Failure

Han JH, Hwang SO, Cha KC, Roh YI, Kim SJ, Kim HS, Jung1 WJ

Purpose Acute decompensated heart failure (ADHF) caused by ischemic heart disease is associated with higher mortality and requires immediate diagnosis. Recently, novel methods to diagnose non-ST elevation myocardial infarction (NSTEMI) using...
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The Effectiveness of Postoperative Chemotherapy on pT1bN0 and pT2N0 Gastric Cancer Patients with Risk Factors: An International Dual-Center Analysis

Yang K, Chen MX, Choi YY, Zhou ZG, Hyung WJ, Noh SH, Hu JK

Purpose This study aimed to investigate the effectiveness of postoperative chemotherapy in pT1bN0 and pT2N0 gastric cancer patients with high risk factors. Materials and Methods Clinicopathological data of gastric cancer patients, who had...
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Relation Between Tumor Size and Lymph Node Metastasis According to Subtypes of Breast Cancer

Min SK, Lee SK, Woo J, Jung SM, Ryu JM, Yu J, Lee JE, Kim SW, Chae BJ, Nam SJ

Purpose: Tumor size and lymph node metastasis are important factors that contribute to the progression of breast cancer. We aimed to analyze the relationship between tumor size and lymph node...
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Revisiting Riehl’s Melanosis in Korean Patients: Clinicopathological Features, Blood Chemistry, and Immunohistochemistry

Won KH, Kim JE, Choi ME, Lee YJ, Jung CJ, Park BJ, Lee WJ, Won CH, Lee MW, Choi JH, Chang SE

  • KMID: 2512407
  • Korean J Dermatol.
  • 2021 Jan;59(1):45-53.
Background: Riehl’s melanosis of the face and neck has been reported in middle-aged women who have darker skin types. Recently, cases of Riehl’s melanosis have been on the rise in...
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Medication Use Evaluation of Denosumab in Postmenopausal Women with Osteoporosis or Osteopenia

Lim SH, Jung WJ, Chae Jw, Kang C, Yun Hy

Background: The indication of denosumab for osteoporosis was expanded from second-line to first-line therapy in 2019. The aim of this study was to evaluate the efficacy of denosumab as both...
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Longevity of Cross-linked Hyaluronic Acid Filler Depending on Injection Depth: In Vivo Study Using a Small Animal Model

Lee WJ, Choi ME, Lee KH, Yang HJ, Kang HJ, Won KH, Won CH

  • KMID: 2506582
  • Korean J Dermatol.
  • 2020 Sep;58(8):516-524.
Background: Hyaluronic acid (HA) is the material used most often for soft tissue augmentation. Both agent factors, such as type of fillers and host factors, including technical manipulation, are known...
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Association of Sleep Duration with Hand Grip Strength in Adults: Korea National Health and Nutrition Examination Survey (2014–2017)

Kim WJ, Choi JK, Kwon HJ, Shin JY, Oh EJ, Kim KJ

Background: Hand grip strength (HGS) is used clinically with regards to rehabilitation and recommended as a basic measure in determiningmusculoskeletal function, weakness, and disability. The purpose of this study was...
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Changes in Characteristics of Patients with Liver Cirrhosis Visiting a Tertiary Hospital over 15 Years: a Retrospective Multi-Center Study in Korea

Jang WY, Chung WJ, Jang BK, Hwang JS, Lee HJ, Hwang MJ, Kweon YO, Tak WY, Park SY, Lee SH, Lee CH, Kim BS, Kim SH, Suh JI, Park JG

Background: Liver cirrhosis has become a heavy burden not only for patients, but also for our society. However, little is known about the recent changes in clinical outcomes and characteristics...
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Preliminary Investigation of Association between Methylphenidate and Serum Growth Markers in Children with Attention-Deficit/Hyperactivity Disorder: A Cross-Sectional Case-Control Study

Kim WJ, Bang YR, Kang JW, Yoo JH, Kim SH, Park JH

  • KMID: 2504045
  • J Korean Acad Child Adolesc Psychiatry.
  • 2020 Jul;31(3):154-160.
  • doi: 10.5765/jkacap.200014
Objectives: It remains unclear whether methylphenidate (MPH) has yadverse effects on growth in children. This study aimed to investigate the association of MPH with serum biological markers of growth in...
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Rare Occurrence of Internal Auditory Canal Stenosis Accompanied With Congenital Facial Palsy in a 3-Month-Old Infant: A Case Report

Park SH, Kim WJ, Lim YJ, On CW, Park JH, Min EH

Internal auditory canal (IAC) stenosis with hypoplasia of the facial and vestibulocochlear nerves is a rare cause of congenital facial palsy. In this case report, a 3-month-old female infant was...
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Contrasting Prognostic Effects of Tumor-Infiltrating Lymphocyte Density in Cardia and Non-cardia Gastric Adenocarcinomas

Kim HI, Kim SY, Yu JE, Shin SJ, Roh YH, Cheong JH, Hyung WJ, Noh SH, Park CG, Lee HJ

Purpose: This study sought to investigate the prognostic significance of tumor-infiltrating lymphocytes (TILs) in relation to tumor location within the stomach. Materials and Methods: The densities and prognostic significance of TIL...
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Application of Segmental Phase Angle for Assessment of Post-Stroke Complex Regional Pain Syndrome

Park SH, Kim WJ, Jo GY, Kwon JK

Our objective is to evaluate the applicability of segmental phase angle (PhA) via bioelectrical impedance analysis (BIA) for post-stroke complex regional pain syndrome (CRPS). Due to its noninvasiveness and convenience,...
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Reverse shoulder arthroplasty with os acromiale

Shin WJ, Lee HJ, An KY

Function and strength of the deltoid muscle are important in reverse shoulder arthroplasty (RSA). Moreover, location and shape of the acromion, clavicle, and scapular spine, which are origins of the...
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