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Apatinib Combined with Local Irradiation Leads to Systemic TumorControl via Reversal of Immunosuppressive Tumor Microenvironmentin Lung Cancer

Liang Lj, Hu Cx, Wen Yx, Geng Xw, Chen T, Gu Gq, Wang L, Xia Yy, Liu Y, Fei Jy, Dong J, Zhao Fh, Ahongjiang Y, Hui Ky, Jiang Xd

Purpose This study aimed to investigate the potential systemic antitumor effects of stereotactic ablative radiotherapy (SABR) and apatinib (a novel vascular endothelial growth factor receptor 2 inhibitor) via reversing the immunosuppressive tumor microenvironment...
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