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Role of IFNLR1 gene in PRRSV infection of PAM cells

Qin M, Chen W, Li Z, Wang L, Ma L, Geng J, Zhang Y, Zhao J, Zeng Y

Background: Interferon lambda receptor 1 (IFNLR1) is a type II cytokine receptor that clings to interleukins IL-28A, IL29B, and IL-29 referred to as type III IFNs (IFN-λs). IFN-λs act through...
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Arthrodesis of the Knee Using a Retrograde Femoral Intramedullary Nail: Technical Report

Wang L, Kim SH

Arthrodesis is one of the last options available to obtain a stable, painless knee in patients who are unable to undergo reconstructive surgery due to a damaged knee joint. A...
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Dysregulated Free Fatty Acid Receptor 2 Exacerbates Colonic Adenoma Formation in ApcMin/+ Mice: Relation to Metabolism and Gut Microbiota Composition

Huang YW, Lin CW, Pan P, Echeveste CE, Dong A, Oshima K, Yearsley M, Yu J, Wang LS

Free fatty acid receptor 2 (FFAR2) has been reported as a tumor suppressor in colon cancer development. The current study investigated the effects of FFAR2 signaling on energy metabolism and...
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Relationships Among Character Strengths, Self-efficacy, Social Support, Depression, and Psychological Well-being of Hospital Nurses

Xie J, Liu M, Zhong Z, Zhang Q, Zhou J, Wang L, Ma K, Ding S, Zhang X, Sun Q, Cheng AS

Purpose: From the perspective of positive psychology, our study aimed to explore depressive symptomsand psychological well-being among Chinese nurses, as well as analyze the impacts of characterstrengths, self-efficacy and social...
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Assessment of the Severity of Coronavirus Disease:Quantitative Computed Tomography Parameters versusSemiquantitative Visual Score

Yin X, Min X, Nan Y, Feng Z, Li B, Cai W, Xi X, Wang L

Objective: To compare the accuracies of quantitative computed tomography (CT) parameters and semiquantitative visualscore in evaluating clinical classification of severity of coronavirus disease (COVID-19). Materials and Methods: We retrospectively enrolled 187...
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Diffusion tensor imaging of the C1-C3 dorsal root ganglia and greater occipital nerve for cervicogenic headache

Wang L, Shen J, Das S, Yang H

Background: Previous studies showed neurography and tractography of the greater occipital nerve (GON). The purpose of this study was determining diffusion tensor imaging (DTI) parameters of bilateral GONs and dorsal...
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Analysis of Risk Factors for a Poor Prognosis in Patients with Anti-N-Methyl-D-Aspartate Receptor Encephalitis and Construction of a Prognostic Composite Score

Mo Y, Wang L, Zhu L, Li F, Yu G, Luo Y, Ni M

Background and Purpose: Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is the most-common form of autoimmune encephalitis, but its early diagnosis is challenging. This study aimed to identify the risk factors for a poor...
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Adipose Tissue-Derived Stem Cells from Type 2 Diabetics Reveal Conservative Alterations in Multidimensional Characteristics

Wang L, Zhang L, Liang X, Zou J, Liu N, Liu T, Wang G, Ding X, Liu Y, Zhang B, Liang R, Wang S

Background and Objectives: Adipose tissue-derived mesenchymal stem cells (ASCs) are recognized as an advantaged source for the prevention and treatment of diverse diseases including type 2 diabetes mellitus (T2DM). However,...
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Anti-colonic Inflammation by Black Raspberries through Regulating Toll-like Receptor-4 Signaling in Interlukin-10 Knockout Mice

Huang YW, Echeveste CE, Oshima K, Zhang J, Yearsley M, Yu J, Wang LS

Ulcerative colitis (UC) is a chronic inflammatory disease of the colon, with a steadily rising prevalence in Western and newly industrialized countries. UC patients have a cancer incidence as high...
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Human Recombinant Apyrase Therapy Protects Against Myocardial Ischemia/Reperfusion Injury and Preserves Left Ventricular Systolic Function in Rats, as Evaluated by 7T Cardiovascular Magnetic Resonance Imaging

Xu Z, Chen W, Zhang R, Wang L, Chen R, Zheng J, Gao F

Objective: The occurrence of intramyocardial hemorrhage (IMH) and microvascular obstruction (MVO) in myocardial infarction (MI), known as severe ischemia/reperfusion injury (IRI), has been associated with adverse remodeling. APT102, a soluble...
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The Chinese Version of the Work Control Scale for Nurses: Modifying the Translation and Psychometric Testing

Wen F, Wang L, Fang Z, Zhu J, Zhang Y

Purpose: The aim of the study was to modify and test the psychometric properties of the Chinese version of the work control scale (C-WCS). Methods: The translated scale was administered to...
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Enhanced recovery after surgery strategy for cirrhosis patients undergoing hepatectomy: experience in a single research center

Zheng Y, Wang L, Wu F, Rong W, Liu Y, Zhang K, Wu J

Purpose: To evaluate the safety and effectiveness of an enhanced recovery after surgery (ERAS) programme after curative liver resection in cirrhotic hepatocellular carcinoma (HCC) patients. Methods: One hundred sixty-two patients were...
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LncRNA LINC00313 Knockdown InhibitsTumorigenesis and Metastasis in HumanOsteosarcoma by Upregulating FOSL2through Sponging miR-342-3p

Chen H, Wahafu P, Wang L, Chen X

Purpose: Osteosarcoma (OS) is the most common primary bone tumor, with high morbidity in infants and adolescents. Long noncoding RNA LINC00313 has been found to modulate papillary thyroid cancer tumorigenesis and...
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Clinical response and safety of apatinib monotherapy in recurrent, metastatic cervical cancer after failure of chemotherapy:a retrospective study

Xiao Y, Cheng H, Wang L, Yu X

Objective: To observe the safety and short-term efficacy of apatinib in the treatment of recurrent, metastatic cervical cancer in patients who have already received more than two kinds of comprehensive...
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EBV-miR-BHRF1-1 Targets p53 Gene: Potential Role in Epstein-BarrVirus Associated Chronic Lymphocytic Leukemia

Xu DM, Kong YL, Wang L, Zhu HY, Wu JZ, Xia Y, Li Y, Qin SC, Fan L, Li JY, Liang JH, Xu W

Purpose The purpose of this study was to investigate the prognostic impact of Epstein-Barr virus (EBV)–microRNA (miRNA, miR)-BHRF1-1 with chronic lymphocytic leukemia (CLL) as well as role of EBV-miR-BHRF1-1 in p53 gene. Materials and...
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Apatinib Combined with Local Irradiation Leads to Systemic TumorControl via Reversal of Immunosuppressive Tumor Microenvironmentin Lung Cancer

Liang Lj, Hu Cx, Wen Yx, Geng Xw, Chen T, Gu Gq, Wang L, Xia Yy, Liu Y, Fei Jy, Dong J, Zhao Fh, Ahongjiang Y, Hui Ky, Jiang Xd

Purpose This study aimed to investigate the potential systemic antitumor effects of stereotactic ablative radiotherapy (SABR) and apatinib (a novel vascular endothelial growth factor receptor 2 inhibitor) via reversing the immunosuppressive tumor microenvironment...
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Effect of chronic kidney disease on outcomes of total joint arthroplasty: a meta-analysis

Kim CW, Kim HJ, Lee CR, Wang L, Rhee SJ

Background: This meta-analysis was conducted to evaluate the differences in preoperative comorbidities, postoperative mortality, the rate of periprosthetic joint infection (PJI), and revision rate after total joint arthroplasty (TJA) between...
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Combination of multiplex reverse transcription recombinase polymerase amplification assay and capillary electrophoresis provides high sensitive and high-throughput simultaneous detection of avian influenza virus subtypes

Tsai SK, Chen CC, Lin HJ, Lin HY, Chen TT, Wang LC

The pandemic of avian influenza viruses (AIVs) in Asia has caused enormous economic loss in poultry industry and human health threat, especially clade 2.3.4.4 H5 and H7 subtypes in recent...
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Metformin Attenuates Liver Fat Content: Finding from Schizophrenia Patients with Olanzapine-induced Weight Gain

Wang L, Chen Y, Sui Yc, Tan Xq, Zhou Z, Li N, Xu Lp

Objective: This study was performed to evaluate the efficacy of metformin on liver fat content (LFC) in first episode schizophrenia patients with olanzapine-induced weight gain, and the relationship between the...
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Risk Factors for Work-Related Musculoskeletal Disorders Among Intensive Care Unit Nurses in China: A Structural Equation Model Approach

Yang S, Li L, Wang L, Zeng J, Li Y

Purpose This study explored the direct and indirect effects of risk factors of work-related musculoskeletal disorders (WRMDs) in nurses working in intensive care units (ICUs). Methods A cross-sectional study design was used. ICU...
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