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Differential Impact of Cigarette Smoking on Fracture Risks in Subjective Cognitive Decline and Dementia: A Nationwide Longitudinal Study

Um YH, Wang SM, Han Kd, Kim NY, Kang DW, Na HR, Lee CU, Lim HK

Objective We aimed to explore the differential impact of cigarette smoking on fracture risks in SCD and dementia. Methods A nationwide population-based cohort study design was used. Out of all the...
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Orexin and Alzheimer’s Disease: A New Perspective

Um YH, Lim HK

Orexin’s role in human cognition has recently been emphasized and emerging evidences indicate its close relationship with Alzheimer’s disease (AD). This review aimed to demonstrate recent research on the relationship...
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Effects of Moderate Intensity Exercise on the Cortical Thickness and Subcortical Volumes of Preclinical Alzheimer’s Disease Patients: A Pilot Study

Um YH, Wang SM, Kim NY, Kang DW, Na HR, Lee CU, Lim HK

Objective We aimed to explore the impact of moderate intensity exercise on the cortical thickness and subcortical volumes of preclinical Alzheimer’s disease (AD) patients. Methods Sixty-three preclinical AD patients with magnetic...
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Correlation between Sleep and C-reactive Protein of Patients in Amnestic Mild Cognitive Impairment and Alzheimer’s Dementia

Kim HY, Hong SC, Jeong JH, Seo HJ, Kim TW, Kim SM, Oh JH, Chung JS, Um YH

Objective: Sleep affects systemic inflammation and amyloid deposition, and sleep disturbance is known to be a risk factor for cognitive decline. To date, literatures on the relationship between peripheral inflammatory...
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The Development of Evidence-Based Guideline for Diagnosis and Management of Headache in Korea

Kim SM, Ko YH, Yoon S, Kang WS, Kim HG, Park HY, Shin C, Um YH, Youn S, Lee JH, Jang SH, Jeon SW, Jeon HJ, Chung S, Choi JW, Han KM, Lee SY

OBJECTIVE: We aimed to develop the clinical guideline for headache by the systematic review and synthesis of existing evidence-based guidelines. The purpose of developing the guideline was to improve the...
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Anxiety and Depression of the Patients with Hematological Malignancies during Hospitalization for Hematopoietic Stem Cell Transplantation

Seo HJ, Baek YG, Cho BS, Kim TS, Um YH, Chae JH

OBJECTIVE: This study aimed to assess the anxiety and depression in patients undergoing hematopoietic stem cell transplantation (HSCT). METHODS: Eighty-seven adult patients with various hematologic diseases, who were scheduled to receive...
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Discontinuation Rate of Doxepin in Insomnia Patients

Lee JH, Kim SM, Hong SC, Seo HJ, Kim TW, Um YH, Jeong JH

OBJECTIVES: We aimed to investigate the discontinuation rate and reasons of doxepin base prescription pattern in insomnia outpatients of psychiatry department of a university hospital. METHODS: 534 patients prescribed doxepin were...
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Diagnostic Validity of an Automated Probabilistic Tractography in Amnestic Mild Cognitive Impairment

Jung WS, Um YH, Kang DW, Lee CU, Woo YS, Bahk WM, Lim HK

OBJECTIVE: Although several prior works showed the white matter (WM) integrity changes in amnestic mild cognitive impairment (aMCI) and Alzheimer's disease, it is still unclear the diagnostic accuracy of the...
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Limbic Encephalitis Manifesting as Selective Amnesia and Seizure-like Activity: A Case Report

Kim SY, Um YH, Lim SC, Jeong JH

Limbic encephalitis (LE) is characterized by short-term memory loss, disorientation, agitation, seizures, and histopathological evidence of medial temporal lobe inflammation. Leucine-rich, glioma inactivated 1 (LGI-1) is an auto-antigen associated with...
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Prediction of Treatment Response to Donepezil using Automated Hippocampal Subfields Volumes Segmentation in Patients with Mild Alzheimer's Disease

Um YH, Kim TW, Jeong JH, Seo HJ, Han JH, Hong SC, Lee CU, Lim HK

Previous studies reported some relationships between donepezil treatment and hippocampus in Alzheimer's disease (AD). However, due to methodological limitations, their close relationships remain unclear. The aim of this study is...
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Depression and Mortality in People with Type 2 Diabetes Mellitus, 2003 to 2013: A Nationwide Population-Based Cohort Study

Jeong JH, Um YH, Ko SH, Park JH, Park JY, Han K, Ko KS, Task Force Team for Diabetes Fact Sheet of the Korean Diabetes Association

BACKGROUND: Previous reports have demonstrated a bidirectional relationship between depression and diabetes mellitus (DM), accentuating a need for more intensive depression screening in DM patients. There is a relative paucity...
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A Case Report of a 37-Year-Old Alzheimer's Disease Patient with Prominent Striatum Amyloid Retention

Um YH, Choi WH, Jung WS, Park YH, Lee CU, Lim HK

With recent advancement in amyloid imaging, diagnostic application of this new modality has become a great interest among researchers. New ligands, such as 18F- florbetaben, florbetapir and flutemetamol, have been...
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Sleep Problems as Predictors in Attention-Deficit Hyperactivity Disorder: Causal Mechanisms, Consequences and Treatment

Um YH, Hong SC, Jeong JH

Attention-deficit hyperactivity disorder (ADHD) is notorious for its debilitating consequences and early age of onset. The need for early diagnosis and intervention has frequently been underscored. Previous studies have attempted...
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Erratum to “Prediction of Treatment Response to Donepezil using Automated Hippocampal Subfields Volumes Segmentation in Patients with Mild Alzheimer's Disease”

Um YH, Kim TW, Jeong JH, Seo HJ, Han JH, Hong SC, Lee CU, Lim HK

Unfortunately, the corresponding author's affiliation was incorrect in the original publication of this article..
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Whole Brain Voxel-Wise Analysis of Cerebral Retention of Beta-Amyloid in Cognitively Normal Older Adults Using ¹⁸F-Florbetaben

Um YH, Choi WH, Jung WS, Park YH, Lee CU, Lim HK

OBJECTIVE: Recently developed 18F-labelled amyloid beta (Aβ) positron emission tomography (PET) tracers have demonstrated potentials to enable more prevalent application of amyloid imaging in the clinical setting. The aim of...
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Visual Hallucinations and Amyloid Deposition in Parkinson's Disease Dementia: A Case Report

Um YH, Kim TW, Jeong JH, Seo HJ, Han JH, Hong SC, Jung WS, Choi WH, Lee CU, Lim HK

Parkinson's disease dementia (PDD) is notorious for its debilitating clinical course and high mortality rates. Consequently, various attempts to investigate predictors of cognitive decline in Parkinson's disease (PD) have been...
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Adjunctive Low-frequency Repetitive Transcranial Magnetic Stimulation over the Right Dorsolateral Prefrontal Cortex in Patients with Treatment-resistant Obsessive-compulsive Disorder: A Randomized Controlled Trial

Seo HJ, Jung YE, Lim HK, Um YH, Lee CU, Chae JH

OBJECTIVE: The present study aimed to evaluate the efficacy of low frequency (LF) repetitive transcranial magnetic stimulation (rTMS) over the right dorsolateral prefrontal cortex (DLPFC) for the treatment of obsessive-compulsive...
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A Voxel Wise Analysis of Cerebral Beta Amyloid Retention in Healthy Controls and Subjects with Amnestic Mild Cognitive Impairment and Alzheimer's Disease

Cho Y, Um YH, Kim TW, Seo HJ, Jeong JH, Hong SC, Han JH, Baek IH, Lim HK

OBJECTIVE: The purpose of the study was to compare cortical amyloid deposition using 18F-florbetaben and positron emission tomography (PET) in healthy controls and subjects with amnestic mild cognitive impairment (aMCI)...
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Three New Records of Mortierella Species Isolated from Crop Field Soil in Korea

Yadav DR, Kim SW, Adhikari M, Um YH, Kim HS, Kim C, Lee HB, Lee YS

Three new fungal species of the genus Mortierella, Mortierella zychae, Mortierella ambigua, and Mortierella indohii, have been reported in Korea. The fungi were encountered during a study on the fungal...
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A New Record of Gongronella butleri Isolated in Korea

Babu AG, Kim SW, Adhikari M, Yadav DR, Um YH, Kim C, Lee HB, Lee YS

We report the isolation of a Gongronella butleri species and describe it based on the analysis of the internal transcribed spacer region of rDNA and morphological characteristics. G. butleri has...
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