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Clinical Characteristics of Bipolar Disorder Patients with Mood Stabilizer-Induced Cognitive Side Effects findings from the REAP-BD Survey in Korea

Shin H, Choi JH, So H, Choi H, Park YC, Tan CH, Lin Sk, Shinfuku N, Park SC, Kim K

Objectives This study aimed to identify differences between bipolar disorder patients who experienced cognitive side effects and those who did not experience cognitive side effects due to prescription of mood...
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Comparisons between non-alcoholic steatohepatitisand alcohol-related hepatocellular carcinoma

Kumar R, Goh BBG, Kam JW, Chang PE, Tan CK

Background/Aims: Non-alcoholic liver disease and alcoholic liver disease begin as simple steatosis that may progress to steatohepatitis and ensuing liver-related complications such as cirrhosis and hepatocellular carcinoma (HCC). We explored...
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2019 Novel Coronavirus (COVID-19) Pneumonia withHemoptysis as the Initial Symptom: CT and ClinicalFeatures

Shi F, Yu Q, Huang W, Tan C

Recently, some global cases of 2019 novel coronavirus (COVID-19) pneumonia have been caused by second- or third-generation transmission of the viral infection, resulting in no traceable epidemiological history. Owing to the...
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Use of Paclitaxel Coated Drug Eluting Technology to Improve Central Vein Patency for Haemodialysis Access Circuits: Any Benefit?

Chong TT, Yap HY, Tan CS, Lee QS, Chan SL, Yan Wee IJ, Tang TY

Purpose: Central venous stenosis is a recurring problem affecting dialysis access patency. Increasing evidence suggests that the use of drug-coated balloons (DCBs) improves target lesion primary patency (TLPP) in dialysis...
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Predictive value of peanut skin prick test, specific IgE in peanut-sensitized children in Singapore

Chong KW, Saffari SE, Chan N, Seah R, Tan CH, Goh SH, Goh A, Loh W

BACKGROUND: The predictive decision points for both peanut skin prick test (SPT) wheal size and serum IgE concentrations, in peanut-sensitized children, have not been evaluated in Singapore. OBJECTIVE: We aim to...
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An Unusual Complication of Colonic Perforation Following Percutaneous Nephrostomy in a Grade IV Blunt Renal Injury Patient

Yan JG, Huei TJ, Lip HT, Mohamad Y, Alwi RI

Percutaneous nephrostomy is relatively safe for temporary urinary diversion. However, colonic perforation due to percutaneous nephrostomy can happen with an incidence of 0.2% as reported in the English literatures. To...
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Clinical Characteristics and Psychotropic Drug Prescription Patterns of Bipolar Disorder Patients with a History of Suicidal Attempts: Findings from the REAP-BD, Korea

Park SC, Kim K, Jang OJ, Kim SG, Lee JG, Park JH, Choi J, Lee DW, Lin SK, Tan CH, Shinfuku N, Park YC

Our study aimed to analyze the clinical characteristics and psychotropic prescription patterns of a history of suicide attempts in South Koreans with bipolar disorder (BD), by using only Korean data...
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Examining Patterns of Polypharmacy in Bipolar Disorder: Findings from the REAP-BD, Korea

Kim K, Yang H, Na E, Lee H, Jang OJ, Yoon HJ, Oh HS, Ham BJ, Park SC, Lin SK, Tan CH, Shinfuku N, Park YC

Based on Korean data from the Research on Asian Psychotropic Prescription Pattern for Bipolar Disorder, this study tried to present prescription patterns in biopolar disorder (BD) and its associated clinical...
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Outcomes of salvage liver transplant for recurrent hepatocellular carcinoma: A comparison with primary liver transplant

Guo Y, Tan EK, Krishnamoorthy TL, Tan CK, Tan BH, Tan TT, Lee SY, Chan CY, Cheow PC, Chung AY, Jeyaraj PR, Goh BK

BACKGROUNDS/AIMS: Salvage liver transplantation (SLT) is a therapeutic strategy for recurrent hepatocellular carcinoma (HCC). However, it remains controversial with compromised survival outcomes and increased perioperative morbidity compared to primary liver...
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Repeat liver resection versus salvage liver transplant for recurrent hepatocellular carcinoma: A propensity score-adjusted and -matched comparison analysis

Guo Y, Tan EK, Syn NL, Krishnamoorthy TL, Tan CK, Lim R, Lee SY, Chan CY, Cheow PC, Chung AY, Jeyaraj PR, Goh BK

BACKGROUNDS/AIMS: Repeat liver resection (RLR) and salvage liver transplantation (SLT) are viable treatment options for recurrent hepatocellular carcinoma (HCC). With possibly superior survival outcomes than RLR, SLT is however, limited...
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Bridging therapies to liver transplantation for hepatocellular carcinoma: A bridge to nowhere?

Tan CH, Yu Y, Tan YR, Lim BL, Iyer SG, Madhavan K, Kow AW

BACKGROUNDS/AIMS: Liver Transplantation (LT) is a recognized treatment for Hepatocellular Carcinoma (HCC). The role of Bridging Therapies (BT) remains controversial. METHODS: From January 2001 to October 2012, 192 patients were referred...
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Differences in High Dose Antipsychotic Prescriptions in Patients with Schizophrenia in Asian Countries/Areas: Findings from the REAP-AP Study

Park YC, Yang SY, Chong MY, Kanba S, Sartorius , Shinfuku N, Tan CH, Park SC

The REAP-AP study recruited 3,746 patients with schizophrenia, in March and April 2016, from 71 centers in 15 Asian countries/territories namely Bangladesh, China, Hong Kong, India, Indonesia, Japan, Korea, Malaysia,...
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Liver lesions detected in a hepatitis B core total antibody-positive patient masquerading as hepatocellular carcinoma: a rare case of peliosis hepatis and a review of the literature

Tan CH, Soon GS, Kow WC

Peliosis Hepatis (PH) is a rare vascular disorder of the liver, characterized by the presence of cystic blood-filled cavities distributed throughout the hepatic parenchyma. The pathogenesis of PH remains controversial....
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Pimecrolimus increases the melanogenesis and migration of melanocytes in vitro

Xu P, Chen J, Tan C, Lai RS, Min ZS

Vitiligo is an intriguing depigmentary disorder and is notoriously difficult to be treated. The ultimate goal of vitiligo treatment is to replenish the lost melanocytes by immigration from hair follicle...
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Treatment of Intracranial Aneurysms with Flow Re-direction Endoluminal Device - A Single Centre Experience with Short-term Follow-up Results

Mahboobani NR, Chong WH, Lam SS, Siu JC, Tan CB, Wong YC

PURPOSE: A flow diverter (FD) is an effective treatment option for intracranial aneurysms. The Flow Re-direction Endoluminal Device (FRED) is a relatively new flow diverter with a unique dual-layer design....
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One Health Perspectives on Emerging Public Health Threats

Ryu S, Kim BI, Lim JS, Tan CS, Chun BC

Antimicrobial resistance and emerging infectious diseases, including avian influenza, Ebola virus disease, and Zika virus disease have significantly affected humankind in recent years. In the premodern era, no distinction was...
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Magnetic Resonance Elastography and Other Magnetic Resonance Imaging Techniques in Chronic Liver Disease: Current Status and Future Directions

Tan CH, Venkatesh

Recent advances in the noninvasive imaging of chronic liver disease have led to improvements in diagnosis, particularly with magnetic resonance imaging (MRI). A comprehensive evaluation of the liver may be...
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A Safe and Efficacious Alternative to Roux-en-Y Gastric Bypass for the Treatment of Morbid Obesity and Type 2 Diabetes - One Anastamosis / Mini Gastric Bypass

Tan CH, Park YS, Kim DW, Lee Y, Ahn SH, Park DJ, Kim HH, Cheng A

Roux-en-y gastric bypass (RYGB) is currently used to treat obesity and metabolic syndrome. It is however technically challenging with a steep learning curve and long operating times. Laparoscopitc mini-gastric bypass...
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Management of Hypertensive Crisis Emergency: A Case Report

Hwang JH, Kim KD, Woo EJ, Lee MH, Tan CC, Park W

Medical emergencies are not rare in dental practice but when an emergency does occur it can be life-threatening. Medical emergency such as hypertensive crisis can be encountered in dental practice...
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