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Erratum: Plasmacytoid Dendritic Cells Contribute to the Protective Immunity Induced by Intranasal Treatment with Fc-fused Interleukin-7 against Lethal Influenza Virus Infection

Kang MC, Park HW, Choi DH, Choi YW, Park Y, Sung YC, Lee SW

In the publication by Kang et al., typographical error has been detected in acknowledgements.
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Plasmacytoid Dendritic Cells Contribute to the Protective Immunity Induced by Intranasal Treatment with Fc-fused Interleukin-7 against Lethal Influenza Virus Infection

Kang MC, Park HW, Choi DH, Choi YW, Park Y, Sung YC, Lee SW

Developing a novel vaccine that can be applied against multiple strains of influenza virus is of utmost importance to human health. Previously, we demonstrated that the intranasal introduction of Fc-fused...
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COMP-Ang1 Potentiates EPC Treatment of Ischemic Brain Injury by Enhancing Angiogenesis Through Activating AKT-mTOR Pathway and Promoting Vascular Migration Through Activating Tie2-FAK Pathway

Moon HE, Byun K, Park HW, Kim JH, Hur J, Park JS, Jun JK, Kim HS, Paek SL, Kim IK, Hwang JH, Kim JW, Kim DG, Sung YC, Koh GY, Song CW, Lee B, Paek SH

Successful recovery from brain ischemia is limited due to poor vascularization surrounding the ischemic zone. Cell therapy with strong angiogenic factors could be an effective strategy to rescue the ischemic...
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In vivo action of IL-27: reciprocal regulation of Th17 and Treg cells in collagen-induced arthritis

Moon SJ, Park JS, Heo YJ, Kang CM, Kim EK, Lim MA, Ryu JG, Park SJ, Park KS, Sung YC, Park SH, Kim HY, Min JK, Cho ML

  • KMID: 2154265
  • Exp Mol Med.
  • 2013 Oct;45(10):e46.
Interleukin (IL)-27 is a novel cytokine of the IL-6/IL-12 family that has been reported to be involved in the pathogenesis of autoimmune diseases and has a pivotal role as both...
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The Past, Present, and Future of Adoptive T Cell Therapy

Choi D, Kim TG, Sung YC

  • KMID: 2424208
  • Immune Netw.
  • 2012 Aug;12(4):139-147.
Although adoptive T cell therapy (ACT) has become a promising immunotherapeutic regime for cancer treatment, its effectiveness has been hindered by several inherent shortcomings regarding safety and efficacy. During the...
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Synergistic Effect of Mesenchymal Stem Cells Infected with Recombinant Adenovirus Expressing Human BDNF on Erectile Function in a Rat Model of Cavernous Nerve Injury

Kim SJ, Choi SW, Hur KJ, Park SH, Sung YC, Ha YS, Cho HJ, Hong SH, Lee JY, Hwang TK, Kim SW

PURPOSE: To evaluate the combined role of mescenchymal stem cells (MSCs) infected with recombinant adenoviruses expressing human BDNF (rAd/hBDNF) on the erectile dysfunction in rat with cavernous nerve injury. MATERIALS AND...
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Transplantation of Muscle-Derived Stem Cells into the Corpus Cavernosum Restores Erectile Function in a Rat Model of Cavernous Nerve Injury

Woo JC, Bae WJ, Kim SJ, Kim SD, Sohn DW, Hong SH, Lee JY, Hwang TK, Sung YC, Kim SW

  • KMID: 2315526
  • Korean J Urol.
  • 2011 May;52(5):359-363.
PURPOSE: Muscle-derived stem cells (MDSCs) harvested from skeletal muscles have the advantage of providing easier access and do not pose the immunogenic risks of embryonic stem cells. We investigated the...
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Serum IP-10 Levels Correlate with the Severity of Liver Histopathology in Patients Infected with Genotype-1 HCV

You CR, Park SH, Jeong SW, Woo HY, Bae SH, Choi JY, Sung YC, Yoon SK

  • KMID: 2284243
  • Gut Liver.
  • 2011 Dec;5(4):506-512.
BACKGROUND/AIMS: Interferon-gamma-inducible protein 10 (IP-10) plays important roles in the pathogenesis of hepatitis C virus (HCV) infection. We investigated the association between serum IP-10 levels and liver pathology in patients...
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Co-Immunization of Plasmid DNA Encoding IL-12 and IL-18 with Bacillus Calmette-Guerin Vaccine against Progressive Tuberculosis

Jeon BY, Eoh H, Ha SJ, Bang H, Kim SC, Sung YC, Cho SN

PURPOSE: Bacillus Calmette-Guerin (BCG) vaccine has widely been used to immunize against tuberculosis, but its protective efficacy is variable in adult pulmonary tuberculosis, while it is not efficiently protective against...
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Codelivery of IL-7 Augments Multigenic HCV DNA Vaccine-induced Antibody as well as Broad T Cell Responses in Cynomolgus Monkeys

Park SH, Song MY, Nam HJ, Im SJ, Sung YC

BACKGROUND: A crucial limitation of DNA vaccines is its weak immunogenicity, especially in terms of eliciting antibody responses in non-human primates or humans; therefore, it is essential to enhance immune...
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Increase of Plasma IL-12/p40 Ratio Induced by the Combined Therapy of DNA Vaccine and Lamivudine Correlates with Sustained Viremia Control in CHB Carriers

Im SJ, Yang SH, Yoon SK, Sung YC

BACKGROUND: We previously reported that IFN-gamma producing T cell responses induced by the combined therapy of DNA vaccine and lamivudine for one year are important for the induction of sustained...
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Enhancement of DNA Vaccine-induced Immune Responses by Influenza Virus NP Gene

Choi SY, Suh YS, Cho JH, Jin HT, Chang J, Sung YC

DNA immunization induces B and T cell responses to various pathogens and tumors. However, these responses are known to be relatively weak and often transient. Thus, novel strategies are necessary...
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Increased in vivo immunological potency of HB-110, a novel therapeutic HBV DNA vaccine, by electroporation

Kim CY, Kang ES, Kim SB, Kim HE, Choi JH, Lee DS, Im SJ, Yang SH, Sung YC, Kim BM, Kim BG

Pulse-induced permeabilization of cellular membranes, generally referred to as electroporation (EP), has been used for years as a tool to increase macromolecule uptake in tissues, including nucleic acids, for gene...
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B Cells Transduced with HPV16 E6/E7-expressing Adenoviral Vector Can Efficiently Induce CTL-dependent Anti-Tumor Immunity

Kim YS, Ko HJ, Kim YJ, Han SH, Lee JM, Chang WS, Jin HT, Sung YC, Kang CY

BACKGROUND: Human papillomavirus (HPV) infection is responsible for cervical cancer, a common cancer in women. Since HPV infection and cancer development are controlled by the host immune system, immunotherapy against...
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The Th17 and Autoimmune Arthritis

Cho ML, Heo YJ, Park JS, Lee SY, Sung YC, Kim HY

Autoimmune arthritis, such as rheumatoid arthritis (RA), is a chronic inflammatory disorder that primarily affects the joints and then results in their progressive destruction. Effector Th cells have been classified...
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Enhancement of Transduction Efficiency and Antitumor Effects of IL-12N220L-expressing Adenovirus by Co-delivery of DOTAP

Youn JI, Jin HT, Sung YC

BACKGROUND: Adenovirus (Ad) vectors have been widely used for many gene therapy applications because of their high transduction ability and broad tropism. However, their utility for cancer gene therapy is...
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Action Mechanism in Immunopathogenesis and Clearance of HBV

Im SJ, Sung YC

  • KMID: 760642
  • Korean J Hepatol.
  • 2006 Jun;12(2):154-162.
Hepatitis B virus (HBV) currently infects more than 400 million people worldwide and they are at risk of developing chronic liver disease, cirrhosis and hepatocellular carcinoma. The immune response to...
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Measurement of HIV-1-specific T Cell Immunity by Using Recombinant Gag Protein

Jeong H, Wie SH, Kim YJ, Kim SI, Kim YR, Kim TG, Yang SH, Sung YC, Kang MW

  • KMID: 2285068
  • Infect Chemother.
  • 2006 Dec;38(6):374-382.
BACKGROUND: HIV-specific immunity, such as strong CD4+ helper and CD8+ cytotoxic T lymphocytes (CTL) responses, develops soon after HIV infection, but usually it can not control HIV replication which ultimately...
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HCV core protein promotes liver fibrogenesis via up-regulation of CTGF with TGF-beta1

Shin JY, Hur W, Wang JS, Jang JW, Kim CW, Bae SH, Jang SK, Yang SH, Sung YC, Kwon OJ, Yoon SK

  • KMID: 755753
  • Exp Mol Med.
  • 2005 Apr;37(2):138-145.
Liver cirrhosis is one of the major complications of hepatitis C virus (HCV) infection, but the mechanisms underlying HCV-related fibrogenesis are still not clear. Although the roles of HCV core...
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Efficient Induction of Th1-type Immune Responses to Hepatitis B Virus Antigens by DNA Prime-Adenovirus Boost

Lee CG, Yang SH, Park SH, Song MK, Choi SY, Sung YC

BACKGROUND: Chronic infection with hepatitis B virus (HBV) affects about 350 million people worldwide, which have a high risk of development of cirrhosis and hepatocellular carcinoma. Treatment of chronic HBV...
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