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Targeted Next-Generation Sequencing of Plasma CellFree DNA in Korean Patients with Hepatocellular Carcinoma

Chae H, Sung PS, Choi H, Kwon A, Kang D, Kim Y, Kim M, Yoon SK

Background: Hepatocellular carcinoma (HCC) is the second-most-common cause of cancer-related deaths worldwide, and an accurate and non-invasive biomarker for the early detection and monitoring of HCC is required. We assessed...
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Management of Hyperacute Stroke during the Coronavirus Disease of 2019 Pandemic: The Modified Code Stroke in a Medical Center in Taiwan

Lin PY, Chang YM, Huang CY, Lin CH, Chuang MT, Chen PL, Sung PS, Chen CH

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Solitary fibrous tumor of the liver mimicking malignancy

Nam HC, Sung PS, Jung ES, Yoon SK

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Successful Sequential Therapy Involving Regorafenib after Failure of Sorafenib in a Patient with Recurrent Hepatocellular Carcinoma after Liver Transplantation

Lee SK, Jang JW, Nam H, Sung PS, Bae SH, Choi JY, Yoon SK

The efficacy and safety of sequential systemic therapy for the treatment of recurrent hepatocellular carcinoma (HCC) after liver transplantation (LT) are not well established. This study describes a successful experience...
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A different detection method reveals a new role of alanine aminotransferase as an indicator of liver fibrosis

Sung PS

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Clinical characteristics of portal hypertension complicated by gastroesophageal varices in patients with myeloproliferative neoplasms

Lee J, Sung PS, Eom KS, Yang H, Lee SK, Bwa AH, Lozada A, Jang JW, Bae SH, Choi JY, Yoon SK

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Early Onset Polymorphic Post-transplant Lymphoproliferative Disease Mimicking a Solitary Necrotizing Abscess in a Graft Liver

Sung PS, Lee J, Lee J, Nam HC, Bae SH, Yoon SK

Although post-transplantation lymphoproliferative disease (PTLD) after liver transplantation is very rare, its prognosis is worse than that of PTLD following other types of solid organ transplantation. Here, we report a...
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Liver Transplantation after Successful Downstaging with Hepatic Arterial Infusion Chemotherapy in a Patient with Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

Nam HC, Sung PS, Chun HJ, Kim DG, Jang JW, Choi JY, Yoon SK

Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. The majority of patients with HCC are diagnosed at advanced disease stages with vascular invasion, where curative approaches are...
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Interferon-free treatment for hepatitis C virus infection induces normalization of extrahepatic type I interferon signaling

Sung PS, Lee EB, Park DJ, Lozada A, Jang JW, Bae SH, Choi JY, Yoon SK

BACKGROUND/AIMS: Hepatitis C virus (HCV) replicates in the peripheral blood mononuclear cells (PBMCs), leading to the production of type I interferons (IFNs). It is well known that the gene expression...
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Transarterial Chemolipiodolization for Hepatocellular Carcinoma with Central Bile Duct Invasion Causing Conjugated Hyperbilirubinemia: Safety and Prognostic Factors for Survival

Yang K, Sung PS, Oh JS, Chun HJ, Jang JW, Bae SH, Choi JY, Yoon SK

BACKGROUND/AIMS: The treatments and outcomes of hepatocellular carcinoma (HCC) with bile duct invasion are not well known. We aimed to confirm the safety of transarterial chemolipiodolization (TACL) and identify prognostic...
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Diagnosis of Liver Fibrosis With Wisteria floribunda Agglutinin-Positive Mac-2 Binding Protein (WFA-M2BP) Among Chronic Hepatitis B Patients

Jekarl DW, Choi H, Lee S, Kwon JH, Lee SW, Yu H, Kim M, Kim Y, Sung PS, Yoon SK

BACKGROUND: Wisteria floribunda agglutinin-positive Mac-2 binding protein (WFA-M2BP) is a protein with altered glycosylation that reacts with lectin, and was recently identified as a useful non-invasive biomarker for the diagnosis...
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Effect of antiviral therapy in reducing perinatal transmission of hepatitis B virus and maternal outcomes after discontinuing them

Seo KI, Bae SH, Sung PS, Park CH, Lee HL, Kim HY, Kim HJ, Jang BH, Jang JW, Yoon SK, Choi JY, Park IY, Lee J, Lee HS, Kim SJ, Kwon JH, Chang UI, Kim CW, Jo SH, Lee Y, Tekle F, Kim JH

BACKGROUND/AIMS: There have been numerous efforts to reduce mother-to-child transmission (MTCT) of hepatitis B virus (HBV) with antiviral agents during pregnancy. However, there are limited data regarding the outcomes of...
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Reactivation of Hepatitis C Virus and Its Clinical Outcomes in Patients Treated with Systemic Chemotherapy or Immunosuppressive Therapy

Lee HL, Bae SH, Jang B, Hwang S, Yang H, Nam HC, Sung PS, Lee SW, Jang JW, Choi JY, Han NI, Song BJ, Lee JW, Yoon SK

BACKGROUND/AIMS: According to the results of several studies, the outcome of hepatitis C virus (HCV) reactivation is not as severe as the outcome of hepatitis B virus reactivation. The aim...
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Comparative Analysis of Liver Injury-Associated Cytokines in Acute Hepatitis A and B

Shin SY, Jeong SH, Sung PS, Lee J, Kim HJ, Lee HW, Shin EC

PURPOSE: Acute hepatitis A (AHA) and acute hepatitis B (AHB) are caused by an acute infection of the hepatitis A virus and the hepatitis B virus, respectively. In both AHA...
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Hemorheological Alteration in Patients Clinically Diagnosed with Chronic Liver Diseases

Jang B, Han JW, Sung PS, Jang JW, Bae SH, Choi JY, Cho YI, Yoon SK

Since liver function is changed by chronic liver diseases, chronic liver disease can lead to different hemorheological alterations during the course of the progression. This study aims to compare alterations...
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Immunogenicity of MenACWY-CRM in Korean Military Recruits: Influence of Tetanus-Diphtheria Toxoid Vaccination on the Vaccine Response to MenACWY-CRM

Kim HW, Park IH, You S, Yu HT, Oh IS, Sung PS, Shin EC, Kim KH

The quadrivalent meningococcal conjugate vaccine (MenACWY-CRM) has been introduced for military recruits in Korea since 2012. This study was performed to evaluate the immunogenicity of MenACWY-CRM in Korean military recruits....
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Immunoproteasome induction is suppressed in hepatitis C virus-infected cells in a protein kinase R-dependent manner

Oh IS, Textoris-Taube K, Sung PS, Kang W, Gorny X, Kähne T, Hong SH, Choi YJ, Cammann C, Naumann M, Kim JH, Park SH, Yoo OJ, Kloetzel P, Seifert U, Shin EC

By changing the relative abundance of generated antigenic peptides through alterations in the proteolytic activity, interferon (IFN)-γ-induced immunoproteasomes influence the outcome of CD8⁺ cytotoxic T lymphocyte responses. In the present...
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Subacute Thyroiditis with Coexisting Papillary Carcinoma

Sung PS, Kim MH, Lim DJ, Choi YH, Kang MI, Cha BY, Bae JS

  • KMID: 2012973
  • J Korean Thyroid Assoc.
  • 2011 May;4(1):58-62.
Subacute thyroiditis with coexisting papillary carcinoma is very rare. Here, we report a case of 36-year-old Korean female with both thyroid diseases. She presented with acute onset of anterior neck...
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Hemophagocytic Lymphohistiocytosis (HLH) Associated with Plasmodium vivax Infection: Case Report and Review of the Literature

Sung PS, Kim IH, Lee JH, Park JW

Hemophagocytic lymphohistiocytosis (HLH) is an unusual syndrome characterized by fever, hepatosplenomegaly, cytopenias, hypertriglyceridemia, hypofibrinogenemia, and pathologic findings of hemophagocytosis in the bone marrow and other tissues. HLH may be familial...
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Differences in the patterns and outcomes of enhanced viral replication between hepatitis C virus and hepatitis B virus in patients with hepatocellular carcinoma during transarterial chemolipiodolization

Sung PS, Bae SH, Jang JW, Song DS, Kim HY, Yoo SH, Park CH, Kwon JH, Song MJ, You CR, Choi JY, Yoon SK

BACKGROUND/AIMS: Enhanced replication of hepatitis C virus (HCV) is well described in the setting of moderate to severe immunosuppression. The aims of this retrospective study were to determine the incidence...
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