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The Anti-Inflammatory Effect of Sulforaphane in Mice with Experimental Autoimmune Encephalomyelitis

Yoo IH, Kim MJ, Kim J, Sung JJ, Park ST, Ahn SW

BACKGROUND: Multiple sclerosis (MS) is an immune-associated inflammatory disorder of the central nervous system and results in serious disability. Although many disease-modifying therapy drugs have been developed, these drugs have...
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B Cell Immunophenotyping and Transcriptional Profiles of Memory B Cells in Patients with Myasthenia Gravis

Min YG, Park C, Kwon YN, Shin JY, Sung JJ, Hong YH

Myasthenia gravis (MG) is an autoimmune neuromuscular junction disorders mediated by various autoantibodies. Although most patients with MG require chronic immunosuppressive treatment to control disease activity, appropriate surveillance biomarkers that...
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Characteristics of South Korean Patients with Hereditary Transthyretin Amyloidosis

Choi K, Seok JM, Kim BJ, Choi YC, Shin HY, Sunwoo IN, Kim DS, Sung JJ, Lee GY, Jeon ES, Kim NH, Min JH, Oh J

BACKGROUND AND PURPOSE: This retrospective cross-sectional study included 18 patients from unrelated families harboring mutations of the transthyretin gene (TTR), and analyzed their characteristics and geographical distribution in South Korea. METHODS:...
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Neurolymphomatosis presenting as brachial plexopathy with involvement of cranial nerves

Lee HJ, Kim KS, Song P, Lee JJ, Sung JJ, Choi K, Kim B, Cho JY

Neurolymphomatosis (NL) is a rare disease characterized by lymphomatous invasion of the cranial or peripheral nerves by lymphoma. A high suspicion is important due to the various presenting symptoms mandating...
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The Anti-Inflammatory Effects of Oral-Formulated Tacrolimus in Mice with Experimental Autoimmune Encephalomyelitis

Kim MJ, Sung JJ, Kim SH, Kim JM, Jeon GS, Mun SK, Ahn SW

Multiple sclerosis (MS) is a T-lymphocyte-mediated autoimmune disease that is characterized by inflammation in the central nervous system (CNS). Although many disease-modifying therapies (DMTs) are presumed effective in patients with...
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Epidemiology and Clinical Characteristics of Zika Virus Infections Imported into Korea from March to October 2016

Yoon D, Shin SH, Jang HC, Kim ES, Song EH, Moon SM, Shin SY, Choe PG, Sung JJ, Choi EH, Oh MD, Jee Y, Kim NJ

Zika is a re-emerging, mosquito-borne viral infection, which has been recently shown to cause microcephaly and Guillain-Barré syndrome. Since 2015 the number of infected patients has increased significantly in South...
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Current perception threshold in diabetic sensory polyneuropathy with normal routine nerve conduction study

Park KS, Kwon YC, Youn M, Park YS, Hong YH, Sung JJ

BACKGROUND: Routine nerve conduction study (NCS) can only be used to evaluate the function of large fibers, and the results of NCS are often normal in patients with distal sensory...
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A confusing case of multiple sclerosis and central nervous system graft versus host disease

Yoon BN, Ha CK, Lee KW, Park SH, Sung JJ

No abstract available.
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Reference Range of Respiratory Muscle Strength and Its Clinical Application in Amyotrophic Lateral Sclerosis: A Single-Center Study

Park KH, Kim RB, Yang J, Oh JH, Park SY, Kim DG, Shin JY, Sung JJ

BACKGROUND AND PURPOSE: Evaluating respiratory function is important in neuromuscular diseases. This study explored the reference ranges of the maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP), and sniff nasal...
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Nemaline Myopathy Presenting as Adult-onset Distal Myopathy

Park KH, Sohn SY, Shin JY, Kim JS, Park SH, Kim JS, Sung JJ

No abstract available.
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Periodic Limb Movements During Sleep Associated with Human T-Lymphotropic Virus Type I-Associated Myelopathy

Oh JH, Kim JS, Kang SY, Sung JJ

Periodic limb movements during sleep (PLMS) are frequently observed in the general population, although such movements may be associated with a variety of medical and neurological disorders. Human T-lymphotropic virus...
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Rapid Progression of Sporadic ALS in a Patient Carrying SOD1 p.Gly13Arg Mutation

Kim MJ, Bae JH, Kim JM, Kim HR, Yoon BN, Sung JJ, Ahn SW

Amyotrophic lateral sclerosis (ALS), the most common adult onset motor neuron disease, is pathologically characterized by progressive loss of the upper and lower motor neurons. Mutations in the Cu/Zn superoxide...
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Subacute Sensorimotor Polyneuropathy Associated with Autoimmune Hepatitis

Park KH, Sohn SY, Sung JJ, Lee KW, Hong YH

No abstract available.
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Immunohistochemical Expression and Clinical Significance of Suggested Stem Cell Markers in Hepatocellular Carcinoma

Sung JJ, Noh SJ, Bae JS, Park HS, Jang KY, Chung MJ, Moon WS

BACKGROUND: Increasing evidence has shown that tumor initiation and growth are nourished by a small subpopulation of cancer stem cells (CSCs) within the tumor mass. CSCs are posited to be...
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Clinical presentations of Chlamydia pneumoniae in children hospitalized for acute respiratory infections: a comparison to Mycoplasma pneumonia

Sung JJ, Kim EJ, Sun YH, Jeon IS, Tchah H, Ryoo E, Son DW, Cho HK, Cho HJ, Kim NY

PURPOSE: Chlamydia pneumoniae is a common intracellular bacterial pathogen and plays an important role in acute respiratory infections. The purpose of this study was to investigate clinical presentations of C....
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Neuro-Behcet's Disease Presenting as Hypertrophic Pachymeningitis

Yoon BN, Kim SJ, Lim MJ, Han JY, Lee KW, Sung JJ, Ha CK, Choi SH

A 25-year-old man presented with blurred vision and chronic headache. His brain MRI revealed bilateral frontal pachymeningeal enhancement with leptomeningeal enhancement. The patient had experienced recurrent oral ulcer and had...
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Modulation of SOD1 Subcellular Localization by Transfection with Wild- or Mutant-type SOD1 in Primary Neuron and Astrocyte Cultures from ALS Mice

Lee DY, Jeon GS, Shim YM, Seong SY, Lee KW, Sung JJ

Amyotrophic lateral sclerosis (ALS) is a fatal neurological disorder characterized by selective degeneration of motor neurons. Mutant superoxide dismutase 1 (SOD1) is often found as aggregates in the cytoplasm in...
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Hepatitis associated with Mycoplasma pneumoniae infection in Korean children: a prospective study

Kim KW, Sung JJ, Tchah H, Ryoo E, Cho HK, Sun YH, Cho KH, Son DW, Jeon IS, Kim YM

PURPOSE: Mycoplasma pneumoniae (MP) infection is a major cause of respiratory infection in school-aged children. Extrapulmonary manifestations of MP infection are common, but liver involvement has been rarely reported. The...
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Survey of Secondary Infections within the Households of Newly Diagnosed Tuberculosis Patients

Lee MH, Sung JJ, Eun BW, Cho HK

PURPOSE: The purpose of this study is to investigate secondary infections within the households of newly diagnosed tuberculosis patients. METHODS: We collected data on household infections of tuberculosis patients by retrospective...
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Pattern of Respiratory Deterioration in Sporadic Amyotrophic Lateral Sclerosis According to Onset Lesion by Using Respiratory Function Tests

Kim DG, Hong YH, Shin JY, Lee KW, Park KS, Seong SY, Sung JJ

Most amyotrophic lateral sclerosis (ALS) patients show focal onset of upper and lower motor neuron signs and spread of symptoms to other regions or the other side clinically. Progression patterns...
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