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Detection and genetic analysis of zoonotic hepatitis E virus, rotavirus, and sapovirus in pigs

Lyoo EL, Park BJ, Ahn HS, Han SH, Go HJ, Kim DH, Lee JB, Park SY, Song CS, Lee SW, Choi IS

The zoonotic transmission of viral diseases to humans is a serious public health concern. Pigs are frequently a major reservoir for several zoonotic viral diseases. Therefore, periodic surveillance is needed...
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Detection of hepatitis E virus genotypes 3 and 4 in pig farms in Korea

Kim YH, Park BJ, Ahn HS, Han SH, Go HJ, Kim DH, Lee JB, Park SY, Song CS, Lee SW, Choi IS

Zoonotic transmission of hepatitis E virus (HEV) is mostly mediated by HEV-3 and HEV-4 genotypes, and domestic pigs are an important reservoir of these genotypes. A survey of 14 pig...
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Evaluation of immunocontraceptive vaccine composed of gonadotropin-releasing hormone conjugated with granulocyte-macrophage colony-stimulating factor in male rats

Park BJ, Kim YH, Ahn HS, Han SH, Go HJ, Lee JB, Park SY, Song CS, Lee SW, Choi IS

Surgical castration performed to reduce male-associated problems results in pain and microbial infections in male animals. Therefore, immunocontraception, which is mediated by the animal's own antibodies against reproductive hormones, has...
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Experimental infection of dogs with highly pathogenic avian influenza virus (H5N8)

Yuk SS, Lee DH, Park JK, Tseren-Ochir EO, Kwon JH, Noh JY, Song CS

During the highly pathogenic avian influenza (HPAI) H5N8 virus outbreak in Korea, a dog in layer farm contaminated by H5N8 was reported seropositive for HPAI H5N8. To investigate the possibility...
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Optimized clade 2.3.2.1c H5N1 recombinant-vaccine strains against highly pathogenic avian influenza

Jang JW, Lee CY, Kim IH, Choi JG, Lee YJ, Yuk SS, Lee JH, Song CS, Kim JH, Kwon HJ

A/Puerto Rico/8/34 (PR8)-derived recombinant viruses have been used for seasonal flu vaccines; however, they are insufficient for vaccines against some human-fatal H5N1 highly pathogenic avian influenza (HPAI) viruses (HPAIV) due...
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Long-term clinical outcome of acute myocardial infarction according to the early revascularization method: a comparison of primary percutaneous coronary interventions and fibrinolysis followed by routine invasive treatment

Min HK, Park JY, Choi JW, Ryu SK, Kim S, Song CS, Kim DS, Song CW, Kim SJ, Kim YB

BACKGROUND: This study was conducted to provide a comparison between the clinical outcomes of primary percutaneous coronary intervention (PCI) and that of fibrinolysis followed by routine invasive treatment in ST...
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Molecular characterization of highly pathogenic avian influenza H5N8 viruses isolated from Baikal teals found dead during a 2014 outbreak in Korea

Kim SH, Hur M, Suh JH, Woo C, Wang SJ, Park ER, Hwang J, An IJ, Jo SD, Shin JH, Yu SD, Choi K, Lee DH, Song CS

Nineteen highly pathogenic avian influenza (HPAI) H5N8 viruses were isolated from wild birds in the Donglim reservoir in Gochang, Jeonbuk province, Korea, which was first reported to be an outbreak...
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Field Cancerization in Sporadic Colon Cancer

Park SK, Song CS, Yang HJ, Jung YS, Choi KY, Koo DH, Kim KE, Jeong KU, Kim HO, Kim H, Chun HK, Park DI

BACKGROUND/AIMS: Aberrant DNA methylation has a specific role in field cancerization. Certain molecular markers, including secreted frizzled-related protein 2 (SFRP2), tissue factor pathway inhibitor 2 (TFPI2), N-Myc downstream-regulated gene 4...
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Characterization of Lactobacillus reuteri BCLR-42 and Lactobacillus plantarum BCLP-51 as novel dog probiotics with innate immune enhancing properties

Kim EJ, Kang YI, Bang TI, Lee MH, Lee SW, Choi IS, Song CS, Lee JB, Park SY

Probiotics that are able to provide beneficial effects on animal health have become important ingredients of dog foods. This study was conducted to characterize the probiotic potentials of two strains,...
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Non-operative Treatment of Gastric Ulcer Perforation with Contrast Leakage in an Elderly Patient

Song WI, Song CS, Noh JH, Jeong HY, Kim SS

Peptic ulcer remains an important public health concern due to an aging society and the increasing use of non steroidal anti-inflammatory drugs (NSAIDs). Perforated peptic ulcer is a major life-threatening...
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Viscerotropic velogenic Newcastle disease virus replication in feathers of infected chickens

Lee DH, Kwon JH, Noh JY, Park JK, Yuk SS, Erdene-Ochir TO, Nahm SS, Kwon YK, Lee SW, Song CS

Newcastle disease viruses (NDVs) cause systemic diseases in chickens with high mortality. However, little is known about persistence of NDVs in contaminated tissues from infected birds. In this study, we...
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Hepatitis E virus as an emerging zoonotic pathogen

Park WJ, Park BJ, Ahn HS, Lee JB, Park SY, Song CS, Lee SW, Yoo HS, Choi IS

Hepatitis E outbreaks are a serious public health concern in developing countries. The disease causes acute infections, primarily in young adults. The mortality rate is approximately 2%; however, it can...
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Application of Diagnostic Microarray Technique in Subtyping and Pathotyping of Avian Influenza Viruses Isolated in Mongolia

Kwon JH, Kim JH, Lee DH, Cho H, Hwang SY, Yuk SS, Erdene-Ochir TO, Noh JY, Hong WT, Jeong JH, Jeong S, Gwon GB, Lee SW, Choi IS, Song CS

Asian-lineage H5 highly pathogenic avian influenza (HPAI) viruses have caused continuous outbreaks in poultry and wild birds. Development of rapid and accurate diagnostic methods is needed for preventing further spread...
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Erratum: Field Cancerization in Sporadic Colon Cancer

Park SK, Song CS, Yang HJ, Jung YS, Choi KY, Koo DH, Kim KE, Jeong KU, Kim HO, Kim H, Chun HK, Park DI

In the version of this article initially published, the first affiliation (affiliation number 1) was incorrectly stated as "Division of Gastroentorology, Department of Internal Medicine." The correct affiliation is "Department...
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Augmented immune responses in pigs immunized with an inactivated porcine reproductive and respiratory syndrome virus containing the deglycosylated glycoprotein 5 under field conditions

Lee JA, Lee NH, Lee JB, Park SY, Song CS, Choi IS, Lee SW

PURPOSE: Porcine reproductive and respiratory syndrome virus (PRRSV) leads to major economic losses in the swine industry. Vaccination is the most effective method to control the disease by PRRSV. MATERIALS AND...
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Intranasal Administration Model for Evaluating Protection Against Influenza Virus in Mice

Choi SW, Youn HN, Hong W, Park JK, Yuk SS, Kwon JH, Noh JY, Kang JS, Cho KJ, Ryu JJ, Lee JB, Park SY, Choi IS, Lee SW, Song CS

Antiviral activity against Influenza virus of 14 Lactobacillus species isolated from food was monitored. Lactobacillus species were isolated from traditional Korean fermented food. Each live Lactobacillus was administered into the...
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Predictive Factors for Severe Outcomes in Ischemic Colitis

Choi SR, Jee SR, Song GA, Park SJ, Lee JH, Song CS, Park HU

BACKGROUND/AIMS: Ischemic colitis includes a wide clinical spectrum ranging from mild to severe forms. This study aimed to determine the factors that are related to the occurrence of severe ischemic...
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Quantitative measurement of influenza virus replication using consecutive bronchoalveolar lavage in the lower respiratory tract of a ferret model

Lee DH, Kim JI, Lee JW, Chung WH, Park JK, Lee YN, Han JS, Kim HY, Lee SW, Song CS

The ferret is an established animal model of influenza virus infection. Although viral replication in the upper respiratory tract is usually measured with consecutively collected nasal washes, daily evaluation of...
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Progress and hurdles in the development of influenza virus-like particle vaccines for veterinary use

Lee DH, Park JK, Song CS

Virus-like particles (VLPs), which resemble infectious virus particles in structure and morphology, have been proposed to provide a new generation of vaccine candidates against various viral infections. As effective immunogens,...
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Induction of antibody and interferon-gamma production in mice immunized with virus-like particles of swine hepatitis E virus

Song YJ, Park WJ, Lee SK, Lee JB, Park SY, Song CS, Lee SW, Seo KH, Kang YS, Song JY, Choi IS

Virus-like particles (VLPs) composed of the truncated capsid protein of swine hepatitis E virus (HEV) were developed and immune responses of mice immunized with the VLPs were evaluated. IgG titers...
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