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Oxidative stress-induced aberrant G9a activation disturbs RE-1-containing neuron-specific genes expression, leading to degeneration in human SH-SY5Y neuroblastoma cells

Kim HT, Ohn T, Jeong SG, Song A, Jang CH, Cho GW

Oxidative stress-induced neurodegeneration is one of several etiologies underlying neurodegenerative disease. In the present study, we investigated the functional role of histone methyltransferase G9a in oxidative stress-induced degeneration in human...
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Morin Hydrate Inhibits Influenza Virus entry into Host Cells and Has Anti-inflammatory Effect in Influenzainfected Mice

Hong EH, Song aH, Kim SR, Cho J, Jeong B, Yang H, Jeong JH, Ahn JH, Jeong H, Kim SE, Chang SY, Ko HJ

Influenza virus is the major cause of seasonal and pandemic flu. Currently, oseltamivir, a potent and selective inhibitor of neuraminidase of influenza A and B viruses, is the drug of...
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Bullosis Diabeticorum Isolated to the Legs

Yoo DS, Song A, Kim JH, Kim SC

  • KMID: 2504355
  • Korean J Dermatol.
  • 2020 Jul;58(6):433-435.
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Memantine Attenuates Salicylate-induced Tinnitus Possibly by Reducing NR2B Expression in Auditory Cortex of Rat

Jang CH, Lee S, Park IY, Song A, Moon C, Cho GW

Memantine, a noncompetitive antagonist of the N-methyl-d-aspartate (NMDA) receptor, suppresses the release of excessive levels of glutamate that may induce neuronal excitation. Here we investigated the effects of memantine on...
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Clinical and molecular characterization of Korean children with infantile and late-onset Pompe disease: 10 years of experience with enzyme replacement therapy at a single center

Kim MS, Song A, Im M, Huh J, Kang IS, Song J, Yang A, Kim J, Kwon EK, Choi EJ, Han SJ, Park HD, Cho SY, Jin DK

PURPOSE: Pompe disease (PD) is an autosomal recessive disorder caused by a deficiency of acid alpha-glucosidase resulting from pathogenic GAA variants. This study describes the clinical features, genotypes, changes before...
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Comparison of Micronutrient Levels between Oral Feeding and Enteral Feeding in Chronic Stroke Patients

Jeon KS, Yang HS, Yang HE, Song AR, Kwon JW

OBJECTIVE: This study aimed to investigate the difference in micronutrient levels between oral feeding and enteral feeding in chronic stroke patients to assess the risks of enteral feeding. METHODS: Patients with...
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The Different Expression Patterns of HSP22, a Late Embryogenesis Abundant-like Protein, in Hypertrophic H9C2 Cells Induced by NaCl and Angiotensin II

Sung JH, Song A, Park T, Kim E, Lee S

BACKGROUND: High-NaCl diet is a contributing factor for cardiac hypertrophy. The role of HSP22 as a protective protein during cardiac hypertrophy due to hypernatremia is unclear. Accordingly, this study aimed...
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Influence of Resilience and Anger Expression Style on Nursing Work Performance in Emergency Nurses

Jang I, Lee S, Song A, Kim Y

PURPOSE: This study aimed to identify the influence of nurses' resilience and anger expression styles on their nursing work performance in emergency departments. METHODS: The study included 107 nurses from 5...
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Maternal Separation Does Not Produce a Significant Behavioral Change in Mice

Tan S, Ho HS, Song AY, Low J, Je HS

Early life adversities together with genetic predispositions have been associated with elevated risks of neuropsychiatric disorders during later life. In order to investigate the underlying mechanisms, many chronic, early-life stress...
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Sensitization in children with atopic dermatitis: a single center study

Song A, Lee JY, Yang HK, Kim M, Ahn K, Lee SI, Kim J

PURPOSE: There are few recent data regarding allergic sensitization of atopic dermatitis (AD) in Korea. The aim of this study was to investigate patterns of sensitization according to age and...
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Retrograde Endovenous Laser Ablation through Saphenopopliteal Junctional Area for Incompetent Small Saphenous Vein: Comparison with Antegrade Approach

Kim JS, Park SW, Yun IJ, Hwang JJ, Lee SA, Chee HK, Hwang JH

OBJECTIVE: To evaluate the safety and efficacy of retrograde endovenous laser ablation (EVLA) and to compare it with the conventional antegrade EVLA for incompetent small saphenous vein (SSV). MATERIALS AND METHODS:...
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Role of Rotavirus Enterotoxin NSP4 in the Inflammatory Response in Murine Macrophage RAW 264.7 Cells

Kim SA, Than VT, Kim W

The rotavirus nonstructural glycoprotein, NSP4, has been identified as the first viral enterotoxin capable of inducing diarrhea. To investigate the biological function of NSP4 in the inflammatory process, a cDNA...
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Fluoroscopy-Guided Endovenous Sclerotherapy Using a Microcatheter Prior to Endovenous Laser Ablation: Comparison between Liquid and Foam Sclerotherapy for Varicose Tributaries

Park SW, Yun IJ, Hwang JJ, Lee SA, Kim JS, Chee HK, Chang IS

OBJECTIVE: To compare the efficacy and adverse effects of endovenous foam sclerotherapy (EFS) and liquid sclerotherapy (ELS) using a microcatheter for the treatment of varicose tributaries. MATERIALS AND METHODS: From December...
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Efficacy and Safety of Dexmedetomidine for Postoperative Delirium in Adult Cardiac Surgery on Cardiopulmonary Bypass

Park JB, Bang SH, Chee HK, Kim JS, Lee SA, Shin JK

  • KMID: 2288788
  • Korean J Thorac Cardiovasc Surg.
  • 2014 Jun;47(3):249-254.
BACKGROUND: Delirium after cardiac surgery is associated with serious long-term negative outcomes and high costs. The aim of this study is to evaluate neurobehavioral, hemodynamic, and sedative characteristics of dexmedetomidine,...
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Novel Early Predictor of Acute Kidney Injury after Open Heart Surgery under Cadiopulmonary Bypass Using Plasma Neutrophil Gelatinase-Associated Lipocalin

Kim JD, Chee HK, Shin JK, Kim JS, Lee SA, Kim YH, Lee WS, Kim HY

  • KMID: 2288787
  • Korean J Thorac Cardiovasc Surg.
  • 2014 Jun;47(3):240-248.
BACKGROUND: Open heart surgery using cardiopulmonary bypass (CPB) is considered one of the most frequent surgical procedures in which acute kidney injury (AKI) is a frequent and serious complication. The...
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Tuberculous Tenosynovitis and Ulnar Bursitis of the Wrist

Lee SM, Lee WJ, Song AR

Tuberculous infection of the hand is a rare form of extrapulmonary tuberculosis that, left untreated, can cause serious joint and tendon damage. We report the case of a 65-year-old male...
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Effects of Ulinastatin on Postoperative Blood Loss and Hemostasis in Atrioventricular Valve Surgery with Cardiopulmonary Bypass

Park JB, Kim SH, Lee SA, Chung JW, Kim JS, Chee HK

BACKGROUND: Cardiopulmonary bypass (CPB) induces variable systemic inflammatory reactions associated with major organ dysfunction via polymorphonuclear neutrophils (PMNs). Ulinastatin, a urinary trypsin inhibitor, inhibits PMN activity and reduces systemic inflammatory...
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Anti-Inflammatory and Anti-Superbacterial Activity of Polyphenols Isolated from Black Raspberry

Kim SK, Kim H, Kim SA, Park HK, Kim W

The fruit of the black raspberry (Rubus coreanus Miquel) has been employed in traditional medicine, and recent studies have demonstrated its measureable biological activities. However, the root of the black...
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Effect of commercial alcoholic drinks on sound enamel surface of bovine teeth

Song AH, Choi CH

  • KMID: 2321420
  • J Korean Acad Oral Health.
  • 2013 Dec;37(4):180-186.
OBJECTIVES: The purpose of this study was to evaluate the change in surface microhardness of sound enamel of bovine teeth due to commercial alcoholic drinks. METHODS: The experiment group comprised of...
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Application of Cancer Genomics to Solve Unmet Clinical Needs

Lee SH, Sim SH, Kim JY, Cha S, Song A

The large amount of data on cancer genome research has contributed to our understanding of cancer biology. Indeed, the genomics approach has a strong advantage for analyzing multi-factorial and complicated...
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