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Current Challenges Associated with the Use of Human Induced Pluripotent Stem Cell-Derived Organoids in Regenerative Medicine

Lee H, Son MY

Innovative advances in stem cell research have resulted in the development of organoids, which are widely used as in vitro models of human organ development and for disease. The long-term...
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Gamma-aminobutyric acid-salt attenuated high cholesterol/high salt diet induced hypertension in mice

Son M, Oh S, Lee HS, Choi J, Lee BJ, Park JH, Park CH, Son KH, Byun K

Excessive salt intake induces hypertension, but several gamma-aminobutyric acid (GABA) supplements have been shown to reduce blood pressure. GABAsalt, a fermented salt by L. brevis BJ20 containing GABA was prepared...
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Eosinophilic Esophagitis with Angina Pectoris

Son MY, Kim SE, Park SJ, Park MI, Moon W, Kim JH, Jung K, Choi GS, Im SI

Eosinophilic esophagitis (EoE) is an immune or antigen-mediated chronic inflammatory esophageal disorder that is relatively rarein Asian countries. The main symptoms of EoE are dysphagia and food impaction. Although chest...
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Endoscopy-assisted Removal of a Large Rectal Foreign Body by the Valsalva Maneuver

Son MY, Park SJ, Moon W, Oh GM, Park MI, Kim SE, Kim JH, Jung K

Although not as common as foreign bodies in the upper gastrointestinal tract, rectal foreign body insertion is often encountered in emergency departments. The diverse types of rectal foreign bodies have...
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Long-Term Expansion of Functional Human Pluripotent Stem Cell-Derived Hepatic Organoids

Mun SJ, Hong YH, Ahn HS, Ryu JS, Chung KS, Son MJ

A human cell-based liver model capable of long-term expansion and mature hepatic function is a fundamental requirement for pre-clinical drug development. We previously established self-renewing and functionally mature human pluripotent...
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Gallbladder Perforation after Transarterial Chemoembolization in a Patient with a Huge Hepatocellular Carcinoma

Son MY, Han BH, Lee SU, Yun BC, Seo KI, Huh JD

Transarterial chemoembolization (TACE) is a common treatment for unresectable hepatocellular carcinoma (HCC). The most common complications after TACE are non-specific symptoms called post-embolization syndrome, such as abdominal pain or fever....
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Long-term Efficacy of S-1 Monotherapy or Capecitabine Plus Oxaliplatin as Adjuvant Chemotherapy for Patients with Stage II or III Gastric Cancer after Curative Gastrectomy: a Propensity Score-Matched Multicenter Cohort Study

Lee CM, Yoo MW, Son YG, Oh SJ, Kim JH, Kim HI, Park JM, Hur H, Jee YS, Hwang SH, Jin SH, Lee SE, Park JH, Seo KW, Park S, Kim CH, Jeong IH, Lee HH, Choi SI, Lee SI, Kim CY, Kim IH, Son MW, Pak KH, Kim S, Lee MS, Min JS

Purpose: To compare long-term disease-free survival (DFS) between patients receiving tegafur/gimeracil/oteracil (S-1) or capecitabine plus oxaliplatin (CAPOX) adjuvant chemotherapy (AC) for gastric cancer (GC). Materials and Methods: This retrospective multicenter observational...
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Superficial Esophageal Cancer Treated with Multidisciplinary Care: A Case Report

Oh GM, Park MI, Jung KW, Kang SM, Son MY, Kim JH, Moon W, Park SJ

  • KMID: 2503590
  • J Dig Cancer Rep.
  • 2020 Jun;8(1):71-75.
Esophageal cancer is easy to infiltrate and metastasize because esophagus does not have serosa, and is difficult to remove it because esophagus is in the middle of the chest. Because...
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Current Status of Bariatric and Metabolic Surgery in Daejeon and Chungcheong Province: Early Experiences after Public Medical Insurance Coverage in 2019

Kim DW, Kim DH, Kim JG, Son MW, Song GJ, Oh Si, Yoo HM, Lee MS, Lee SK, Lee SE, Jee YS, Hwang SH, Hwang SE, Lee SI

Purpose: This study aimed to investigate the current status of bariatric and metabolic surgery in Daejeon and Chungcheong province and to describe the early experiences after public medical insurance coverage...
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Cytoprotective Effect of Rho Kinase Inhibitors against Oxidative Stress inTrabecular Meshwork Cells

Kim JW, Son MS, Baek MJ

Purpose: We evaluated the protective effect of trabecular outflow drugs, Rho kinase (ROCK) inhibitors against oxidative stress in trabecular meshwork cells. Methods: Primary-cultured human trabecular meshwork cells (HTMCs) were exposed to ROCK...
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Effects of Hydrogen Sulfide and Nitric Oxide on the Permeability of Cultured Trabecular Meshwork Cells

Son MS, Baek MJ, Kim JW

PURPOSE: To investigate the effects of hydrogen sulfide (Hâ‚‚S) on the permeability of a cultured human trabecular meshwork cells (HTMC) monolayer and its interaction with nitric oxide (NO). METHODS: After exposing...
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A Case of a Patent Omphalomesenteric Duct Presenting with Meconium Discharge from the Umbilicus

Han CH, Son MW, Song JH

The omphalomesenteric duct is a link between the primitive midgut and the yolk sac. Normally, the duct obliterates around 6 weeks of gestation, yet varying degrees of incomplete obliteration can...
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Pneumoncoccal Meningitis Presenting with Ventriculitis and Pneumocephalus

Choi SW, Hong YH, Son MJ, Kwon KH, Kim J, Jang MU, Cho SJ

No abstract available.
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Direct Reprogramming to Human Induced Neuronal Progenitors from Fibroblasts of Familial and Sporadic Parkinson’s Disease Patients

Lee M, Sim H, Ahn H, Ha J, Baek A, Jeon YJ, Son MY, Kim J

In Parkinson’s disease (PD) research, human neuroblastoma and immortalized neural cell lines have been widely used as in vitro models. The advancement in the field of reprogramming technology has provided...
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Three-Dimensional Spheroid Formation of Cryopreserved Human Dental Follicle-Derived Stem Cells Enhances Pluripotency and Osteogenic Induction Properties

Kim HJ, Sung IY, Cho YC, Kang MS, Rho GJ, Byun JH, Park WU, Son MG, Park BW, Lee HJ, Kang YH

BACKGROUND: Enhancement and maintenance of the stemness of mesenchymal stem cells (MSCs) is one of the most important factors contributing to the successful in vivo therapeutic application of these cells....
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Treatment of Patients with Cancer in a Secondary Hospital in Korea

Son MK

PURPOSE: This study aims to investigate treatment of cancer patients at a secondary hospital. METHODS: A retrospective analysis was performed with electronic medical records of cancer patients admitted to a secondary...
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Who Can Perform Adjuvant Chemotherapy Treatment for Gastric Cancer? A Multicenter Retrospective Overview of the Current Status in Korea

Min JS, Lee CM, Choi SI, Seo KW, Park DJ, Baik YH, Son MW, Choi WH, Kim S, Pak KH, Kim MG, Park JM, Jeong SH, Lee MS, Park S

PURPOSE: To investigate the current status of adjuvant chemotherapy (AC) regimens in Korea and the difference in efficacy of AC administered by surgical and medical oncologists in patients with stage...
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Effect of Valproic Acid on Nitric Oxide and Nitric Oxide Synthase in Trabecular Meshwork Cell

Son MS, Park CH, Kim JW

PURPOSE: To investigate the effects of valproic acid on the production of nitric oxide (NO) and expression of endothelial nitric oxide synthase (eNOS) in cultured human trabecular meshwork cells (HTMC). METHODS:...
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CORRIGENDUM: Correction of funding statement in ACKNOWLEDGEMENTS section: Epigenetic inactivation of RUNX3 in colorectal cancer

Shin EJ, Kim HJ, Son MW, Ahn TS, Lee HY, Lim DR, Bae SB, Jeon S, Kim H, Jeong D, Lee MS, Kim DS, Noh JS, Baek MJ

Correction of funding statement in ACKNOWLEDGEMENTS section.
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Feasibility of Single-Incision Laparoscopic Appendectomy in Pregnant Women

Son MW, Song GJ, Lee MS

OBJECTIVE: Owing to advances in laparoscopic technique and equipment, a single-port laparoscopic surgery has been applied in various fields of surgery. However, the application of a single-port laparoscopic surgery for...
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