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Participation of D-serine and NR2 subunits in EphA4-mediated trigeminal neuropathic pain

Kim MD, Kim MJ, Son JY, Kim YM, Ju JS, Ahn DK

The present study investigated the participation of D-serine and NR2 in antinociception produced by blockade of central erythropoietin-producing hepatocellular carcinoma (Eph) A4 (EphA4) signaling in rats with trigeminal neuropathic pain....
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A New Histone Deacetylase Inhibitor, MHY4381, Induces Apoptosis via Generation of Reactive Oxygen Species in Human Prostate Cancer Cells

Richa S, Dey P, Park C, Yang J, Son JY, Park JH, Lee SH, Ahn MY, Kim IS, Moon HR, Kim HS

Histone deacetylase (HDAC) inhibitors represent a novel class of anticancer agents, which can be used to inhibit cell proliferation and induce apoptosis in several types of cancer cells. In this...
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Preemptive application of QX-314 attenuates trigeminal neuropathic mechanical allodynia in rats

Yoon JH, Son JY, Kim MJ, Kang SH, Ju JS, Bae YC, Ahn DK

The aim of the present study was to examine the effects of preemptive analgesia on the development of trigeminal neuropathic pain. For this purpose, mechanical allodynia was evaluated in male...
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Blockade of Trigeminal Glutamate Recycling Produces Anti-allodynic Effects in Rats with Inflammatory and Neuropathic Pain

Yang KY, Lee MK, Park MK, Son JY, Ju JS, Ahn DK

The present study investigated the role of spinal glutamate recycling in the development of orofacial inflammatory pain or trigeminal neuropathic pain. Experiments were carried out on male Sprague-Dawley rats weighing...
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Changes in skin reactivity and associated factors in patients sensitized to house dust mites after 1 year of allergen-specific immunotherapy

Son JY, Jung MH, Koh KW, Park EK, Heo JH, Choi GS, Kim HK

BACKGROUND: Allergen-specific immunotherapy (SIT) can significantly improve symptoms and reduce the need for symptomatic medication. OBJECTIVE: The aim of this study was to investigate changes in skin reactivity to house dust...
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Peripheral Cellular Mechanisms of Artemin-induced Thermal Hyperalgesia in Rats

Kim HJ, Yang KY, Lee MK, Park MK, Son JY, Ju JS, Ahn DK

In the present study, we investigated the role of peripheral ionotropic receptors in artemin-induced thermal hyperalgesia in the orofacial area. Male Sprague-Dawley rats weighting 230 to 280 g were used...
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Participation of IL-1β in temporomandibular nociception in rats with CFA-induced inflammation

Ju JS, Choi SH, Kim HJ, Son JY, Ahn DK

The aim of the present study was to develop an animal model for evaluation of temporomandibular (TMJ) nociception under TMJ inflammation. We also investigated the participation of IL-1β in inflammation-induced...
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Age-Related Changes in Immunological Factors and Their Relevance in Allergic Disease Development During Childhood

Chang WS, Kim EJ, Lim YM, Yoon D, Son JY, Park JW, Hong SJ, Cho SH, Lee JS

PURPOSE: Allergic diseases are triggered by Th2-mediated immune reactions to allergens and orchestrated by various immunological factors, including immune cells and cytokines. Although many reports have suggested that childhood is...
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A New Histone Deacetylase Inhibitor, MHY219, Inhibits the Migration of Human Prostate Cancer Cells via HDAC1

De U, Kundu S, Patra N, Ahn MY, Ahn JH, Son JY, Yoon JH, Moon HR, Lee BM, Kim HS

Histone deacetylase (HDAC) inhibitors are considered novel agents for cancer chemotherapy. We previously investigated MHY219, a new HDAC inhibitor, and its potent anticancer activity in human prostate cancer cells. In...
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Experiences with Establishing and Implementing Learning Management System and Computer-Based Test System in Medical College

Park JH, Son JY, Kim S

  • KMID: 2306503
  • Korean J Med Educ.
  • 2012 Sep;24(3):213-222.
PURPOSE: The purpose of this study was to establish an e-learning system to support learning in medical education and identify solutions for improving the system. METHODS: A learning management system (LMS)...
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Anomalous Origin of the Left Coronary Artery from the Pulmonary Artery Initially Visualized by Echocardiography and Multidetector Computed Tomography Coronary Angiography

Kim BH, Park YW, Hong SP, Son JY, Lee YS, Lee JB, Ryu JK, Choi JY, Kim KS, Chang SG

Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital anomaly associated with very high mortality during infancy. We report a 35-year-old female patient...
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Sonographic Finding of Extravaginal Testicular Torsion in a Neonate: A Case Report

Son JY, Kim YJ, Park HS, Jeon HJ, Park HK, Paick SH, Kim HG, Lho YS, Lim SD, Jung SI

  • KMID: 1451388
  • J Korean Soc Ultrasound Med.
  • 2011 Jun;30(2):123-126.
Extravaginal testicular torsion is known to be the predominant mechanism of the torsion in fetuses and neonates. In this torsion, twisting of the spermatic cord occurs outside the sac of...
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A Case of Prothionamide Induced Hepatitis on Patient with Multi-Drug Resistant Pulmonary Tuberculosis

Park JB, Park BH, Son JY, Jung JY, Kim EY, Lim JE, Lee SH, Lee SK, Kim SY, Jung W, Lim S, Lee KJ, Kang YA, Kim YS, Kim SK, Chang J, Choi J, Park MS

The prevalence of multi-drug resistant tuberculosis (MDR-TB), which is resistant to isoniazid and rifampin, has been increasing in Korea. And the side effects of 2nd line anti-tuberculosis medications, including drug-induced...
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Reversible Pulmonary Hypertension in Adolescent with Left Atrial Myxoma

Kim BK, Cho JN, Park HJ, Hong SP, Son JY, Lee JB, Ryu JK, Choi JY, Chang SG, Kim KS

We report a patient of left atrial huge myxoma presenting with severe pulmonary hypertension in adolescents. A patient was a 14-year-old boy presented with sudden onset dyspnea. Transthoracic echocardiographic study...
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Influence of root canal curvature on the screw-in effect of nickel-titanium rotary files in simulated resin root canal

Son JY, Ha JH, Kim YK

OBJECTIVES: Nickel-titanium (Ni-Ti) rotary instruments have some unexpected disadvantages including the tendency to screw-in to the canal. The purpose of this study was to evaluate the influence of root canal...
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Bilioptysis Caused by Bronchobiliary Fistula Secondary to Sclerosing Therapy of Liver Cyst

Lee SH, Lee KJ, Kim SY, Lee SK, Jung KS, Park BH, Jung JY, Son JY, Yoon YW, Kang YA, Park MS, Kim YS, Chang J, Kim SK, Moon JW

  • KMID: 2319377
  • Tuberc Respir Dis.
  • 2010 Aug;69(2):119-123.
Bronchobiliary fistula is a rare disorder consisting of an abnormal communication between the bronchial tree and the biliary duct. In Western countries, trauma, postoperative biliary stenosis, and biliary lithiasis are...
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Non-tuberculous Mycobacterial Lung Disease Presenting as a Solitary Pulmonary Nodule

Kim SY, Lee KJ, Lee SH, Lee SK, Park BH, Jung JY, Son JY, Yoon YW, Shim HS, Kang YA, Park MS, Kim YS, Chang J, Kim SK, Moon JW

  • KMID: 2319348
  • Tuberc Respir Dis.
  • 2010 Jul;69(1):43-47.
We report a case of Mycobacterium intracellulare pulmonary infection presenting as a solitary pulmonary nodule (SPN). A 35-year-old male was admitted due to a SPN in the right upper lobe...
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A Review on Usage and Effectiveness of e-Learning in Medical Education

Park JH, Son JY, Yoo NJ, Kim S

  • KMID: 2306594
  • Korean J Med Educ.
  • 2010 Jun;22(2):91-100.
E-learning is recently considered as a critical strategy to improve the effectiveness and efficiency of education. Although the use of e-learning has been growing rapidly in medical education, there are...
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Effect of air pollution on acute exacerbation of adult asthma in Seoul, Korea: A case-crossover study

Kim SH, Son JY, Lee JT, Kim TB, Park HW, Lee JH, Kim TH, Sohn JW, Shin DH, Park SS, Yoon HJ

  • KMID: 2259159
  • Korean J Med.
  • 2010 Apr;78(4):450-456.
BACKGROUND/AIMS: Outdoor air pollution is an important risk factor for developing asthma and acute exacerbation. Although some epidemiologic studies have shown that increased levels of air pollutants are linked with...
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A Case of Prolonged Extracorporeal Membrane Oxygenation Support for Severe Acute Respiratory Distress Syndrome: A Case Report

Park BH, Chang J, Kim SK, Kang YA, Son JY, Lee KJ, Yoon YW, Jung JA, Lee S, Park MS

When all the conventional treatments have failed for patients with acute respiratory distress syndrome (ARDS), extracorporeal membrane oxygenation (ECMO) can offer these patients a chance to survive. We report here...
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