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Organizing pneumonia as the initial presentation of systemic lupus erythematosus in a Korean adolescent

Kang SY, Kim SY, Choi SH, Sol IS, Kim YH, Shim HS, Lee MJ, Kim KW, Sohn MH

Organizing pneumonia is characterized histologically by the formation of granulation-tissue plugs within the lumens of small airways. It was reported in association with various disorders including infection, drug reactions and...
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Rodent Leukocyte Isolation and Radiolabeling for Inflammation Imaging Study

Kim EM, Oh PS, Boud F, Jeong HJ, Lim ST, Sohn MH

Purpose: The objective of this study was to describe to develop methods of rodent leukocyte isolation and radiolabeling for in vivo inflammation imaging. Methods: Thigh muscle inflammation was induced by injection...
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Radioactivity Reduction of 2-Deoxy-2-[18F] Fluoro-D-Glucose by Milkand Ursodeoxycholic Acid in Preclinical Study

Jeong HJ, Bagalkot TR, Kim HS, Han YH, Kim M, Lim ST, Sohn MH

Purpose 2-Deoxy-2-[18F] fluoro-d-glucose positron emission tomography (18F-FDG-PET) is a less-invasive and widely used diagnostic tool for detection of malignant tumors. However, prolonged retention of 18F-FDG in the body increases radiation exposure. This...
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Delayed-Onset Anaphylaxis Caused by IgE Response to Influenza Vaccination

Kim MJ, Shim DH, Cha HR, Kim CB, Kim SY, Park JH, Sohn MH, Lee JM, Kim KW

Influenza vaccine-associated anaphylaxis is a very rare allergic reaction to vaccines, but the most concerning and life-threatening adverse reaction. Although the safety of influenza vaccines has been well documented, occasional...
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Activated Leukocyte Cell Adhesion Molecule Modulates Th2 Immune Response in Atopic Dermatitis

Oh MS, Hong JY, Kim MN, Kwak EJ, Kim SY, Kim EG, Lee KE, Kim YS, Jee HM, Kim SH, Sol IS, Park CO, Kim KW, Sohn MH

PURPOSE: Activated leukocyte cell adhesion molecule (ALCAM), a member of the immunoglobulin superfamily, is highly expressed on dendritic cells. ALCAM and its receptor CD6 are co-stimulatory molecules in the immunological...
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Effects of Vacuuming Mattresses on Allergic Rhinitis Symptoms in Children

Jeon YH, Lee YJ, Sohn MH, Lee HR

PURPOSE: To evaluate the effects of daily vacuuming of mattresses on the concentration of house dust mite (HDM) allergens and on allergic rhinitis (AR) symptoms in children sensitized to HDM. METHODS:...
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Reduction Rate of Specific IgE Level as a Predictor of Persistent Egg Allergy in Children

Kim JD, Kim SY, Kwak EJ, Sol IS, Kim MJ, Kim YH, Kim KW, Sohn MH

PURPOSE: Egg is the most common food allergen in infants. However, the natural course of egg allergy has not been fully elucidated. This study aimed to describe clinical characteristics and...
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Usefulness of bronchodilator response as an index of asthma control in children

Kim JD, Kim SY, Kim YH, Kim KW, Sohn MH, Sol IS

PURPOSE: Assessing asthma control is important for proper management, and various indices for objective assessment of asthma control, such as fractional exhaled nitric oxide (FeNO) and asthma control test (ACT)...
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Prescription Patterns and Burden of Pediatric Asthma in Korea

Sol IS, Kim YH, Kim SY, Choi SH, Kim JD, Kim BO, Moon JE, Kim KW, Sohn MH

PURPOSE: This study aimed to estimate the prevalence, prescription pattern and burden of pediatric asthma in Korea by analyzing the National Health Insurance (NHI) claims data. METHODS: We retrospectively analyzed the...
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Pediatric Home Mechanical Ventilation in Korea: the Present Situation and Future Strategy

Park M, Jang H, Sol IS, Kim SY, Kim YS, Kim YH, Sohn MH, Kim KW

BACKGROUND: The number of children using home mechanical ventilation (HMV) has increased markedly in Europe and North America, but little is known about the situation in Korea. We described the...
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Nutritional Intervention of a Pediatric Patient with Congenital Bronchomalacia and Gastroesophageal Reflux Disease: a Case Report

Shin KH, Kim KW, Lee SM, Kim SY, Kim MJ, Sohn MH, Lee H

Gastroesophageal reflux disease (GERD) is closely related to respiratory issues. We reported the case about the nutrition intervention given to a male infant with congenital bronchomalacia, GERD, and recurrent pneumonia....
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Clinical application of the Pediatric Acute Lung Injury Consensus Conference definition of acute respiratory distress syndrome

Kim BR, Kim SY, Sol IS, Kim YH, Kim KW, Sohn MH, Kim KE

PURPOSE: Despite improved quality of intensive care, acute respiratory distress syndrome (ARDS) significantly contributes to mortality in critically ill children. As pre-existing definitions of ARDS were adult-oriented standards, the Pediatric...
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Cesarean section does not increase the prevalence of allergic disease within 3 years of age in the offsprings

Kim HI, Nam S, Park Y, Jung YJ, Kim HY, Kim KW, Sohn MH, Kim YH, Lee JH, Hong SJ, Kwon JY

OBJECTIVE: In this study, we evaluated the prevalence of allergic disease in offsprings delivered via the delivery modes of vaginal delivery vs. planned Cesarean section vs. Cesarean section with labor. METHODS:...
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Validation of Pediatric Index of Mortality 3 for Predicting Mortality among Patients Admitted to a Pediatric Intensive Care Unit

Jung JH, Sol IS, Kim MJ, Kim YH, Kim KW, Sohn MH

BACKGROUND: The objective of this study was to evaluate the usefulness of the newest version of the pediatric index of mortality (PIM) 3 for predicting mortality and validating PIM 3...
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Etiology and clinical feature of oral allergy syndrome in children

Park YA, Jeong KU, Kim YH, Sol IS, Kim KW, Sohn MH, Lee SY, Kim KE

PURPOSE: Oral allergy syndrome (OAS) is a unique allergic reaction to fresh fruits or vegetables, which is caused by cross-reactivity between foods and pollens. This study was conducted to investigate...
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Isolated pulmonary Langerhans cell histiocytosis in a 10-month-old infant

Jang H, Kim YH, Kim KW, Sohn MH, Lyu CJ

Langerhans cell histiocytosis (LCH) is characterized by clonal proliferation and accumulation of abnormal dendritic (Langerhans) cells in various organs. Pulmonary involvement, although rare in children, has been reported in 20%–50%...
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Dyspnea Perception During Induced Bronchoconstriction Is Complicated by the Inhaled Methacholine in Children With Clinical Asthma

Choi YJ, Suh DI, Sohn MH, Koh YY

PURPOSE: Dyspnea is not widely utilized as an indicator of asthma provocation despite its universal presentation. We hypothesized that dyspnea severity was proportionate with the lung function decline, methacholine dose-step,...
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Life-threatening Hemorrhage Caused by Mandibular Arteriovenous Malformation: A Case Report

Kim DW, Sol IS, Kim MJ, Kim SY, Kim JD, Choi BS, Kim YH, Kim DJ, Kim BM, Jung SY, Nam W, Kim KW, Sohn MH, Kim KE

Arteriovenous malformation (AVM) of the mandible is a rare vascular condition that can manifest as a wide range of symptoms and, on rare occasions, cause fatal hemorrhage. The symptoms of...
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German Cockroach Extract Induces Matrix Metalloproteinase-1 Expression, Leading to Tight Junction Disruption in Human Airway Epithelial Cells

Lee KE, Jee HM, Hong JY, Kim MN, Oh MS, Kim YS, Kim KW, Kim KE, Sohn MH

PURPOSE: Cockroach exposure is a pivotal cause of asthma. Tight junctions are intercellular structures required for maintenance of the barrier function of the airway epithelium, which is impaired in this...
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Oxygenation Index in the First 24 Hours after the Diagnosis of Acute Respiratory Distress Syndrome as a Surrogate Metric for Risk Stratification in Children

Kim SY, Kim B, Choi SH, Kim JD, Sol IS, Kim MJ, Kim YH, Kim KW, Sohn MH, Kim KE

BACKGROUND: The diagnosis of pediatric acute respiratory distress syndrome (PARDS) is a pragmatic decision based on the degree of hypoxia at the time of onset. We aimed to determine whether...
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