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Diallyl Biphenyl-Type Neolignans Have a Pharmacophore of PPARα/γ Dual Modulators

Han Y, Liu J, Ahn S, An S, Ko H, Shin JC, Jin SH, Ki MW, Lee SH, Lee KH, Shin SS, Choi WJ, Noh M

Adiponectin secretion-promoting compounds have therapeutic potentials in human metabolic diseases. Diallyl biphenyl-type neolignan compounds, magnolol, honokiol, and 4-O-methylhonokiol, from a Magnolia officinalis extract were screened as adiponectin-secretion promoting compounds in...
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Early Intervention Reduces the Spread of COVID-19 in Long-Term Care Facilities in the Republic of Korea

Park SY, Choi G, Lee H, Kim Ny, Lee Sy, Kim K, Shin S, Jang E, Moon Y, Oh K, Choi J, Lee S, Kim YM, Kim J, Yi S, Gwack J, Park O, Park YJ

This study describes the epidemiological characteristics of coronavirus disease 2019 (COVID-19) based on reported cases from long-term care facilities. As of April 20th, 2020, 3 long-term care facilities in a...
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HDL Subclass Analysis in Predicting Metabolic Syndrome in Koreans With High HDL Cholesterol Levels

Yang HS, Hur M, Kim H, Kim SJ, Shin S, Di Somma S, on behalf of the GREAT Network

BACKGROUND: High-density lipoprotein cholesterol (HDL-C) is a complex mixture of subclasses with heterogeneous atheroprotective activities. We analyzed HDL-C subclass in relation to cardiovascular risk and metabolic syndrome (MetS) in a...
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Proper Management of People with Obesity during the COVID-19 Pandemic

Lim S, Shin SM, Nam GE, Jung CH, Koo BK

Since December 2019, countries around the world have been struggling with a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Case series have reported that people with obesity experience...
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Study of the fracture resistance of zirconia on posterior fixed partial dentures based on inter-abutment distance

Park GB, Shin SY

Purpose: Zirconia fixed partial dentures with mandibular 2nd premolar and 2nd molar as abutments are fabricated and then the effects of inter-abutment distance on fracture resistance of zirconia fixed partial...
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Should we regularly evaluate the neurodevelopmental status of moderate and late preterm infants?

Shin SM

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New genotype classification and molecular characterization of canine and feline parvoviruses

Chung HC, Kim SJ, Nguyen VG, Shin S, Kim JY, Lim SK, Park YH, Park B

Background: Canine parvovirus (CPV) and feline panleukopenia (FPV) cause severe intestinal disease and leukopenia. Objectives: In Korea, there have been a few studies on Korean FPV and CPV-2 strains. We attempted...
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Positive association of breastfeeding on respiratory syncytial virus infection in hospitalized infants: a multicenter retrospective study

Jang MJ, Kim YJ, Hong S, Na J, Hwang JH, Shin SM, Ahn YM

Background: Breastfeeding reportedly reduces the overall frequency of infections. Respiratory syncytial virus (RSV), the most common respiratory pathogen in infants, involves recurrent wheezing and has a pathogenic mechanism related to...
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A Systematic Review on Peer Support Services related to the Mental Health Services Utilization for People with Severe Mental Illness

Shin S, Choi H

Purpose: The purpose of this study was to systematically review peer support services related to mental health services utilization by people with severe mental illness and to identify core strategies...
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Copeptin with high-sensitivity troponin at presentation is not inferior to serial troponin measurements for ruling out acute myocardial infarction

Kim KS, Suh GJ, Song SH, Jung YS, Kim T, Shin SM, Kang MW, Lee MS

Objective We aimed to compare the multi-marker strategy (copeptin and high-sensitivity cardiac troponin I [hs-cTnI]) with serial hs-cTnI measurements to rule out acute myocardial infarction (AMI) in patients with chest...
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Genetic Characterization of Molecular Targets in Korean Patients with Gastrointestinal Stromal Tumors

Park J, Yoo HM, Sul HJ, Shin S, Lee SW, Kim JG

PURPOSE: Gastrointestinal stromal tumors (GISTs) frequently harbor activating gene mutations in either KIT or platelet-derived growth factor receptor A (PDGFRA) and are highly responsive to several selective tyrosine kinase inhibitors....
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Views on Precision Medicine among Health Professionals in Korea: A Mixed Methods Study

Cho HN, Shin SY, Hwangbo B, Chang YJ, Cho J, Kong SY, Choi KS, Lee ES

This study aimed to investigate awareness, attitudes, and perspectives on precision medicine among health professionals in Korea and to identify issues that need to be addressed before implementing precision medicine....
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Erratum: Correction of Author Name and Affiliation in the Article “Artificial Intelligence in Health Care: Current Applications and Issues”

Park CW, Seo SW, Kang N, Ko B, Choi BW, Park CM, Chang DK, Kim H, Kim H, Lee H, Jang J, Ye JC, Jeon JH, Seo JB, Kim KJ, Jung KH, Kim N, Paek S, Shin SY, Yoo S, Choi YS, Kim Y, Yoon HJ

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Artificial Intelligence in Health Care: Current Applications and Issues

Park CW, Seo SW, Kang N, Ko BS, Choi BW, Park CM, Chang DK, Kim H, Kim Hc, Lee Hn, Jang Jh, Ye JC, Jeon JH, Seo JB, Kim KJ, Jung KH, Kim N, Paek Sw, Shin SY, Yoo Sy, Choi YS, Kim Y, Yoon HJ

In recent years, artificial intelligence (AI) technologies have greatly advanced and become a reality in many areas of our daily lives. In the health care field, numerous efforts are being...
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Bonding of conventional provisional resin to 3D printed resin: the role of surface treatments and type of repair resins

Lim NK, Shin SY

PURPOSE This study evaluated the shear bond strength between 3D printed provisional resin and conventional provisional resin depending on type of conventional provisional resin and different surface treatments of 3D printed...
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Complement 4 levels of a 4-year-old girl with angioedema

Shin S, Lee YT, Lee KY, Park J, Lee JH, Yang EA

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Serum PD-1 Levels Change with Immunotherapy Response but Do Not Predict Prognosis in Patients with Hepatocellular Carcinoma

Lee HW, Cho KJ, Shin SY, Kim HY, Lee EJ, Kim BK, Kim SU, Park JY, Kim DY, Ahn SH, Han KH

BACKGROUND/AIMS: Programmed death receptor 1 (PD-1) is a promising new target for treatment of patients with hepatocellular carcinoma (HCC). A high expression level of programmed death-ligand 1 (PD-L1) is a...
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Current status and future direction of digital health in Korea

Shin SY

Recently, digital health has gained the attention of physicians, patients, and healthcare industries. Digital health, a broad umbrella term, can be defined as an emerging health area that uses brand...
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Development and Validation of a Person-Centered Perioperative Nursing Scale

Shin S, Kang J

PURPOSE: The purpose of this study was to develop a scale to measure person-centered perioperative nursing (PCPON) and validate its psychometric properties. METHODS: The preliminary items of the PCPON scale were...
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Outcome of Neonates with Agenesis of Septum Pellucidum: A Retrospective Single Center Study

Kim YH, Lee YK, Ko SY, Shin SM

PURPOSE: Agenesis of the septum pellucidum (ASP) is a very rare disease that can be isolated or associated with other brain abnormalities. The neurological prognosis of isolated ASP remains controversial....
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