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Detection of Germline Mutations in Breast Cancer Patients with Clinical Features of Hereditary Cancer Syndrome Using a Multi-Gene Panel Test

Shin HC, Lee HB, Yoo TK, Lee ES, Kim RN, Park B, Yoon KA, Park C, Lee ES, Moon HG, Noh DY, Kong SY, Han W

Purpose Hereditary cancer syndrome means that inherited genetic mutations can increase a person's risk of developing cancer. We assessed the frequency of germline mutations using an nextgeneration sequencing (NGS)–based multiple-gene panel...
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Anticancer effects of D-pinitol in human oral squamous carcinoma cells

Shin HC, Bang TH, Kang HM, Park BS, Kim IR

D-pinitol is an analog of 3-methoxy-D-chiro-inositol found in beans and plants. D-pinitol has anti-inflammatory, antidiabetic, and anticancer effects. Additionally, D-pinitol induces apoptosis and inhibits metastasis in breast and prostate cancers....
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Liver Abscess Caused by Klebsiella oxytoca with Hepatic Artery Pseudoaneurysm: A Case Report

Lee JY, Lee HN, Lee WH, Shin HC, Kim SS, Hwang JA

Hepatic artery pseudoaneurysm is a rare but potentially life-threatening condition that usually occurs after trauma. Early recognition and prompt management are essential for preventing catastrophic consequences, such as hemoperitoneum. We...
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Establishment of NOAEL for intracavernous injections of human bone marrow-derived mesenchymal stem cells in rats

Kim JK, Jang MJ, Kim BH, Choi KR, Song G, Shin HC, Suh N, Kim YM, You D, Ahn TY, Kim CS

PURPOSE: To assess the possible negative health effects of human bone marrow-derived mesenchymal stem cells (hBMSCs) on fertility and early embryonic development following intracavernous injections in rats. MATERIALS AND METHODS: A...
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Left-Sided Cisterna Chyli: a Case Report on a Rare Normal Anatomic Structure

Seo JH, Hwang JA, Shin HC, Kim SS, Park CH, Lee HN

The cisterna chyli, a dilated lymphatic sac in the retrocrural space, is usually located to the right of the aorta. We report a case of a left-sided cisterna chyli, which...
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A Case Report of Extramedullary Myeloma Mimicking Lymphoma with Extensive Abdominal Involvement

Moon J, Hwang JA, Shin HC, Kim SS, Lee JH, Lee JE, Choi SY, Lee MY

Extramedullary myeloma refers to the presence of myeloma deposits outside the skeletal system and typically indicates a poor prognosis associated with shorter overall survival and progression- free survival. We report...
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Comparison of Clinical Outcomes between Plastic Stent and Novel Lumen-apposing Metal Stent for Endoscopic Ultrasound-Guided Drainage of Peripancreatic Fluid Collections

Shin HC, Cho CM, Jung MK, Yeo SJ

BACKGROUND/AIMS: Endoscopic ultrasound (EUS)-guided transmural drainage for peripancreatic fluid collections (PFCs) has gained wide acceptance as a nonsurgical intervention. Although a lumen-apposing metal stent (LAMS) was recently introduced, there are...
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Tumor-Associated Macrophages as Potential Prognostic Biomarkers of Invasive Breast Cancer

Jeong H, Hwang I, Kang SH, Shin HC, Kwon SY

PURPOSE: Tumor-associated macrophages (TAMs) are activated macrophages associated with tumor progression in various cancers. TAMs can polarize M1 or M2 type. M1 has a pro-inflammatory function and kills pathogens. Conversely,...
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Contralateral Breast Cancer and Ipsilateral Breast Tumor Recurrence in BRCA1/2 Carriers and Non-Carriers at High-Risk of Hereditary Breast Cancer

Yoon KH, Chae S, Kang E, Shin HC, Kim JH, Kim IA, Park SY, Kim SW, Kim EK

PURPOSE: We evaluated the risk of contralateral breast cancer (CBC) and ipsilateral breast tumor recurrence (IBTR) and investigated the predictive factors for CBC and IBTR in breast cancer patients with...
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Development of Electrical Neural Stimulator Generating Periodic and Non-periodic Signals and Supporting Closed-loop Experimental System

An H, Shin HC

It is essential to build a system to generate proper neural stimulus signals with adjusting parameters. We developed a stimulator with up to four channels for separate settings in periodic...
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Successful Removal of 15-year-old Pacemaker Leads by Weight and pulley method

Kim HW, Shin HC, Jin HY, Seo JS, Jang JS, Yang TH, Kim DK, Kim DS

Extraction of old pacemaker leads remains a complex procedure owing to fibrotic encapsulation and lead adhesions. We report a case of extraction of 15-year-old pacemaker leads by weight and pulley...
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Hypoxic Preconditioned Mesenchymal Stromal Cell Therapy in a Rat Model of Renal Ischemia-reperfusion Injury: Development of Optimal Protocol to Potentiate Therapeutic Efficacy

Jang MJ, You D, Park JY, Kim K, Aum J, Lee C, Song G, Shin HC, Suh N, Kim YM, Kim CS

Although previous and ongoing clinical studies have used stromal cells during renal ischemia-reperfusion injury (IRI), there is little consensus regarding the optimal protocol. We aimed to optimize the protocol for...
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Therapeutic Effects of Growth Factor Cocktail Including Fibroblast Growth Factor 9 in Patients with Pattern Hair Loss

Ro BI, Lee SY, Kim JB, Shin HC

BACKGROUND: A growth factor cocktail (GFC) including fibroblast growth factor 9 (FGF9) in combination with microneedling is an effective and safe treatment for patients with androgenetic alopecia (AGA). However, there...
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Erratum: Diagnostic Performance of Intravascular Ultrasound-Derived Minimal Lumen Area to Predict Functionally Significant Non-Left Main Coronary Artery Disease: a Meta-Analysis

Jang JS, Shin HC, Bae JS, Jin HY, Seo JS, Yang TH, Kim DK, Cho KI, Kim BH, Park YH, Je HG, Kim DS

In the article, the weighted overall mean MLA cut-off value has been miscalculated. Tha authors deeply apologize for any inconvenience it may have caused.
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Erratum to: Characteristics and Cardiomyogenic Potential of RatFetal Cardiac Progenitor Cells at Different Developmental Stage

Thanh TN, Shin HC, Kim HR, Park SR, Kim J, Choi BH

There are some errors in the published article. The authors would like to make corrections in the original version of the article
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Characteristics and Cardiomyogenic Potential of Rat Fetal Cardiac Progenitor Cells at Different Developmental Stage

Thanh TN, Shin HC, Kim HR, Park SR, Kim J, Choi BH

In recent years, several kinds of cardiac progenitor cells have been identified and isolated from heart tissue. These cells showed differentiation potential into cardiomyocytes, smooth muscle cells, and endothelial cells...
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Combined Use of Neutrophil to Lymphocyte Ratio and C-Reactive Protein Level to Predict Clinical Outcomes in Acute Myocardial Infarction Patients Undergoing Percutaneous Coronary Intervention

Shin HC, Jang JS, Jin HY, Seo JS, Yang TH, Kim DK, Kim DS

BACKGROUND AND OBJECTIVES: Both neutrophil to lymphocyte ratio (NLR) and C-reactive protein (CRP) are biomarkers associated with poor prognosis of patients with acute myocardial infarction (AMI). However, the combined usefulness...
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Axillary Lymph Node to Primary Breast Tumor Standardized Uptake Value Ratio from FDG-PET/CT Imaging for Predicting the Necessity for Nodal Dissection in Primary Breast Tumors

Shin HK, Kim MK, Park SJ, Seok JW, Shin HC

PURPOSE: Accurate preoperative detection by radiologic assessment is necessary to specifically identify patients with at least three positive nodes, who can directly undergo axillary lymph node (ALN) dissection, and avoid...
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Prevalence of Neuropathic Pain and Patient-Reported Outcomes in Korean Adults with Chronic Low Back Pain Resulting from Neuropathic Low Back Pain

Kim JH, Hong JT, Lee CS, Kim KS, Suk KS, Kim JH, Park YS, Chang BS, Jun DS, Kim YH, Lee JH, Min WK, Lee JS, Park SY, Oh IS, Hong JY, Shin HC, Kim WK, Kim JH, Lee JK, Kim IS, Ha Y, Im SB, Kim SW, Han IH, Shin JJ, Rim BC, Seo BJ, Kim YJ, Lee J

STUDY DESIGN: A noninterventional, multicenter, cross-sectional study. PURPOSE: We investigated the prevalence of neuropathic pain (NP) and patient-reported outcomes (PROs) of the quality of life (QoL) and functional disability in Korean...
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Patients with Concordant Triple-Negative Phenotype between Primary Breast Cancers and Corresponding Metastases Have Poor Prognosis

Shin HC, Han W, Moon HG, Park IA, Noh DY

PURPOSE: We investigated the prognostic impact of discordance between the receptor status of primary breast cancers and corresponding metastases. METHODS: A total 144 patients with breast cancer and distant metastasis were...
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