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Clinical Application of Sequential Epigenetic Analysis for Diagnosis of Silver–Russell Syndrome

Kim SY, Shin CH, Lee YA, Shin CH, Yang SW, Cho TJ, Ko JM

Background: Silver-Russell syndrome (SRS) is a pre- or post-natal growth retardation disorder caused by (epi)genetic alterations. We evaluated the molecular basis and clinical value of sequential epigenetic analysis in pediatric...
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Evidence-Based Guidelines for the Treatment of Helicobacter pylori Infection in Korea 2020

Jung HK, Kang SJ, Lee YC, Yang HJ, Park SY, Shin CM, Kim SE, Lim HC, Kim JH, Nam SY, Shin WG, Park JM, Choi IJ, Kim JG, Choi M, Korean College of Helicobacter and Upper Gastrointestinal Research

Helicobacter pylori infection is one of the most common infectious diseases worldwide. Although the prevalence of H. pylori is gradually decreasing, approximately half of the world's population still becomes infected...
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Late Passage Cultivation Induces Aged Astrocyte Phenotypes in Rat Primary Cultured Cells

Bang M, Gonzales EL, Shin CY, Kwon KJ

Astrocytes play various important roles such as maintaining brain homeostasis, supporting neurons, and secreting inflammatory mediators to protect the brain cells. In aged subjects, astrocytes show diversely changed phenotypes and...
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Characteristics of the Gut Microbiome of Healthy Young Male Soldiers in South Korea: The Effects of Smoking

Yoon H, Lee DH, Lee JH, Kwon JE, Shin CM, Yang SJ, Park SH, Lee JH, Kang SW, Lee JS, Kim BY

Background/Aims: South Korean soldiers are exposed to similar environmental factors. In this study, we sought to evaluate the gut microbiome of healthy young male soldiers (HYMS) and to identify the...
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Standardization of the Korean Version of the Patient Health Questionnaire-4 (PHQ-4)

Kim HW, Shin C, Lee SH, Han C

Objective: The Patient Health Questionnaire-4 (PHQ-4) has been used for screening owing to ease of use and brevity. In this study, we developed the Korean version of the PHQ-4 and tested...
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Factors Related to Outcomes of Fecal Microbiota Transplantation in Patients with Clostridioides difficile Infection

Yoon H, Shim HI, Seol M, Shin CM, Park YS, Kim N, Lee DH

Background/Aims: The aim of this study was to evaluate factors related to outcomes of fecal microbiota transplantation (FMT) in patients with Clostridioides difficile infection (CDI) and viability of frozen stock...
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Alpha-Synuclein Inclusion Formation in Human Oligodendrocytes

Yoon YS, Ahn WJ, Ricarte D, Ortiz D, Shin CY, Lee SJ, Lee HJ

Multiple system atrophy (MSA) is a neurodegenerative disease characterized by presence of α-synuclein-positive inclusions in the cytoplasm of oligodendrocytes. These glial cytoplasmic inclusions (GCIs) are considered an integral part of...
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Clinical outcomes of the first 300 cases of kidney transplantation: a single-center retrospective cohort study

Koh HW, Koo K, Shin CS, Park HS, Jeong JC, Kim S, Chae DW, Oh JJ, Byun SS, Lee T

Background: Kidney transplantation (KT) is regarded as the most effective treatment for end-stage renal disease. The annual number of KT cases in South Korea has increased rapidly as more centers...
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Usefulness of Ultrasonography in Diagnosis and Management of Tendon Injuries in Hand

Shin CH, Yu SH, Lee CK, Hong HJ, Kim DC, Chung SH

Purpose: Tendon injuries in hand were one of the most frequent injuries caused by trauma. Although consequent tenorrhaphy is frequently conducted, in complete tendon rupture the location of retracted tendon...
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Efficacy of Buspirone Augmentation of Escitalopram in Patients with Major Depressive Disorder with and without Atypical Features: A Randomized, 8 Week, Multicenter, Open-Label Clinical Trial

Shin C, Ko YH, Shim SH, Kim JS, Na KS, Hahn SW, Lee SH

Objective This study investigated the treatment response and cognitive enhancement effects of buspirone augmentation of escitalopram in patients with major depressive disorder (MDD), according to atypical feature subtypes of MDD. Methods...
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Regression of a Large Hyperplastic Polyp after Helicobacter pylori Eradication Treatment

Kang SJ, Shin CM

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Clinical and Radiological Outcomes of Polished Cemented Bipolar Hemiarthroplasty for Intertrochanteric Fractures in Elderly Patients

Kweon SH, Shin CH, Lee YC, Kim MW, Kim TH

Purpose: To evaluate the clinical and radiological outcomes of bipolar hemiarthroplasty using a polished cemented femoral stem for intertrochanteric fractures in elderly patients. Materials and Methods: From July 2005 to May...
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Clinical Perspectives of Parkinson's Disease for Ophthalmologists, Otorhinolaryngologists, Cardiologists, Dentists, Gastroenterologists, Urologists, Physiatrists, and Psychiatrists

Choi JH, Kim JM, Yang HK, Lee HJ, Shin CM, Jeong SJ, Kim WS, Han JW, Yoon IY, Song YS, Bae YJ

Parkinson's disease (PD) is a multisystemic disorder characterized by various non-motor symptoms (NMS) in addition to motor dysfunction. NMS include sleep, ocular, olfactory, throat, cardiovascular, gastrointestinal, genitourinary, or musculoskeletal disorders....
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Cognitive and Emotional Empathy in Young Adolescents: an fMRI Study

Kim EJ, Son JW, Park SK, Chung S, Ghim HR, Lee S, Lee SI, Shin CJ, Kim S, Ju G, Park H, Lee J

  • KMID: 2504042
  • J Korean Acad Child Adolesc Psychiatry.
  • 2020 Jul;31(3):121-130.
  • doi: 10.5765/jkacap.200020
Objectives: We investigated the differences in cognitive and emotional empathic ability between adolescents and adults, and the differences of the brain activation during cognitive and emotional empathy tasks. Methods: Adolescents (aged...
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Alternating Hemiplegia of Childhood in Korea: a Case Report

Shin C, Yoo D, Kim HJ, Jeon B

Alternating hemiplegia of childhood (AHC) is a rare neurodevelopmental disorder characterized by recurrent paroxysmal hemiplegic attacks that affect one or the other side of the body. Up to 74% of...
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Normal and Abnormal Postoperative Imaging Findings after Gastric Oncologic and Bariatric Surgery

Shin CI, Kim SH

Surgical resection remains the primary choice of treatment and the only potentially curative option for gastric carcinoma, and is increasingly performed laparoscopically. Gastric resection represents a challenging procedure, with a...
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Role of Serum Pepsinogen II and Helicobacter pylori Status in the Detection of Diffuse-Type Early Gastric Cancer in Young Individuals in South Korea

Baek SM, Kim N, Kwon YJ, Lee HS, Kim HY, Lee J, Yoon H, Shin CM, Park YS, Lee DH

Background/Aims: The utility of serum pepsinogen (sPG) I and the sPGI/II ratio as biomarkers for screening individuals with gastric cancer (GC) has not been established in Korea. The aim of...
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Therapeutic Response to 20 mg of Esomeprazole Twice Daily in Patients with Gastroesophageal Reflux Disease-related Non-cardiac Chest Pain: An Open-Label Randomized Pilot Study

Choi JK, Shim HI, Shin CM, Yoon H, Park YS, Kim N, Lee DH

Background/Aims: Non-cardiac chest pain (NCCP) is defined as recurrent angina pectoris-like pain without evidence of coronary heart disease, and is usually related to esophageal diseases, such as gastroesophageal reflux disease...
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The Relationship between Insomnia and Somatization According to Types of Work of Firefighters

Yoon H, Ju G, Lee SI, Shin CJ, Son JW, Kim S, Park H, Lee JH

Objectives:Firefighters are always under stress due to their job environment, and they are likely to become psychologically vulnerable due to continuous exposure to traumatic events, which is a stressful situation...
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Transformation of Mature Osteoblasts into Bone Lining Cells and RNA Sequencing-Based Transcriptome Profiling of Mouse Bone during Mechanical Unloading

Hong AR, Kim K, Lee JY, Yang JY, Kim JH, Shin CS, Kim SW

Background: We investigated RNA sequencing-based transcriptome profiling and the transformation of mature osteoblasts into bone lining cells (BLCs) through a lineage tracing study to better understand the effect of mechanical...
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