Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

more+
SELECT FILTER
 
Close

PUBLICATION DATE

17 results
Display

A Practical Utility and Benefit of Pharmacogenetic-based Antidepressant Treatment Strategy for Major Depressive Disorder Patients with Difficult-to-treat

Lee KH, Bahk WM, Lee SJ, Serretti A, Pae CU

Objective: We report the results of pharmacogenomics-based antidepressant treatment (PGXt) results in treating treatment-resistant major depressive disorder (TRD) patients in real practice. Methods: Nine patients were prescribed NeuropharmagenⓇ for selection of...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Possible Modulatory Role of ARC Gene Variants in Mood Disorders

Crisafulli C, Calabrò M, Mandelli L, Wang SM, Lee SJ, Han C, Patkar A, Masand P, Pae CU, Souery D, Mendlewicz J, Serretti A

Objective: The genetic background of mood disorders is gradually emerging through the use of large multicenter samples but a detailed phenotyping is complementary in elucidating the role of modulating variants. Methods:...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
ZNF804A Gene Variants Have a Cross-diagnostic Influence on Psychosis and Treatment Improvement in Mood Disorders

Calabrò M, Mandelli L, Crisafulli C, Nicola MD, Colombo R, Janiri L, Lee SJ, Jun TY, Wang SM, Masand PS, Patkar AA, Han C, Pae CU, Serretti A

Objective: Genetic variations in the gene encoding zinc finger protein 804A gene (ZNF804A) have been associated with major depression and bipolar disorder. In this work we focused on the potential...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Genetics of Treatment Outcomes in Major Depressive Disorder: Present and Future

Fabbri C, Serretti A

Pharmacogenetic testing is a useful and increasingly widespread tool to assist in antidepressant prescription. More than ten antidepressants (including tricyclics, selective serotonin reuptake inhibitors and venlafaxine) have already genetic biomarkers...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Corrigendum: A Pharmacogenomic-based Antidepressant Treatment for Patients with Major Depressive Disorder: Results from an 8-week, Randomized, Single-blinded Clinical Trial

Han Cs, Wang SM, Bahk WM, Lee SJ, Patkar AA, Masand PS, Mandelli L, Pae CU, Serretti A

CITED
export Copy
Close
SHARE
Twitter Facebook
Close
How to Utilize Clinical and Genetic Information for Personalized Treatment of Major Depressive Disorder: Step by Step Strategic Approach

Fabbri C, Serretti A

Depression is the single largest contributor to non-fatal health loss and affects 322 million people globally. The clinical heterogeneity of this disorder shows biological correlates and it makes the personalization...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Pharmacogenetics and Depression: A Critical Perspective

Corponi F, Fabbri C, Serretti A

Depression leads the higher personal and socio-economical burden within psychiatric disorders. Despite the fact that over 40 antidepressants (ADs) are available, suboptimal response still poses a major challenge and is...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Genes Involved in Neurodevelopment, Neuroplasticity and Major Depression: No Association for CACNA1C, CHRNA7 and MAPK1

Calabrò M, Mandelli L, Crisafulli C, Lee SJ, Jun TY, Wang SM, Patkar AA, Masand PS, Han C, Pae CU, Serretti A

OBJECTIVE: Genetics factors are likely to play a role in the risk, clinical presentation and treatment outcome in major depressive disorder (MDD). In this study, we investigated the role of...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Present and Future of Precision Medicine in Psychiatry: Focus on Clinical Psychopharmacology of Antidepressants

Serretti A

Precision medicine is a concept which is recently gaining momentum in all branches of medicine. In particular in psychiatry it is greatly needed given the huge societal costs of psychiatric...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
A Pharmacogenomic-based Antidepressant Treatment for Patients with Major Depressive Disorder: Results from an 8-week, Randomized, Single-blinded Clinical Trial

Han C, Wang SM, Bahk WM, Lee SJ, Patkar AA, Masand PS, Mandelli L, Pae CU, Serretti A

OBJECTIVE: Pharmacogenomic-based antidepressant treatment (PGATx) may result in more precise pharmacotherapy of major depressive disorder (MDD) with better drug therapy guidance. METHODS: An 8-week, randomized, single-blind clinical trial was conducted to...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Age of Onset in Schizophrenia Spectrum Disorders: Complex Interactions between Genetic and Environmental Factors

Mandelli L, Toscano E, Porcelli S, Fabbri C, Serretti A

In this study we evaluated the role of a candidate gene for major psychosis, Sialyltransferase (ST8SIA2), in the risk to develop a schizophrenia spectrum disorders, taking into account exposure to...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Dimensions of Delusions in Major Depression: Socio-demographic and Clinical Correlates in an Unipolar-Bipolar Sample

Zaninotto , Souery D, Calati R, Camardese , Janiri L, Montgomery S, Kasper S, Zohar J, De Ronchi , Mendlewicz J, Serretti A

OBJECTIVE: The present study aims at exploring associations between a continuous measure of distorted thought contents and a set of demographic and clinical features in a sample of unipolar/bipolar depressed...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
CRY1 Variations Impacts on the Depressive Relapse Rate in a Sample of Bipolar Patients

Drago A, Monti B, De Ronchi , Serretti A

OBJECTIVE: A relevant part of the social and personal burden caused by Bipolar Disorder (BD) is related to depressive phases. Authors investigated the genetic impact of a set of variations...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Epistatic Interactions between CREB and CREM Variants in Affective Disorder

Chiesa A, Marsano A, Han C, Lee SJ, Patkar AA, Pae CU, Serretti A

The aim of the present work is to investigate the existence of epistatic interactions possibly influencing psychotropic agents' response between rs6740584 within Cyclic adenosine monophosphate Response Element Binding (CREB) and...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Abelson Helper Integration Site-1 Gene Variants on Major Depressive Disorder and Bipolar Disorder

Porcelli S, Pae CU, Han C, Lee SJ, Patkar AA, Masand PS, Balzarro B, Alberti S, De Ronchi , Serretti A

OBJECTIVE: The present study aimed to explore whether 4 single nucleotide polymorphisms (SNPs) within the AHI1 gene could be associated with major depressive disorder (MD) and bipolar disorder (BD), and...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
No Effect of Serotoninergic Gene Variants on Response to Interpersonal Counseling and Antidepressants in Major Depression

Serretti A, Fabbri C, Pellegrini S, Porcelli S, Politi P, Bellino S, Menchetti , Mariotti V, Demi C, Martinelli V, Cappucciati M, Bozzatello P, Brignolo E, Brambilla , Pae CU, Balestrieri M, De Ronchi

  • KMID: 2316266
  • Psychiatry Investig.
  • 2013 Jun;10(2):180-189.
OBJECTIVE: Gene variants within the serotonin pathway have been associated with major depressive disorder (MDD) treatment outcomes, however a possible different modulation on pharmacological or psychological treatments has never been...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effect of the Dysbindin Gene on Antimanic Agents in Patients with Bipolar I Disorder

Yun DH, Pae CU, Drago A, Mandelli L, De Ronchi , Patkar AA, Paik IH, Serretti A, Kim JJ

OBJECTIVE: We previously reported an association between dysbindin gene (DTNBP1) variants and bipolar I disorder (BID). This paper expands upon previous findings suggesting that DTNBP1 variants may play a role...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2021 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr