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Isolation and Identification of Bioactive Compounds from the Tuber of Brassica oleracea var. gongylodes

Prajapati R, Seong SH, Kim HR, Jung HA, Choi JS

Brassica oleracea var. gongylodes (red kohlrabi) is a biennial herbaceous vegetable whose edible bulbotuber-like stem and leaves are consumed globally. Sliced red kohlrabi tubers were extracted using methanol and the...
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A Case Report on the Dermoscopic Features of Spark’s Nevus

Park JB, Seong SH, Jang JY, Yang MH, Suh KS, Jang MS

Spark’s nevus is a compound word composed of Spitz nevus and Clark’s nevus. It is one of the combined melanocytic nevi which is more common in female and usually presents...
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Relation between Lichen Planus and Hepatitis C Virus Infection

Park JB, Seong SH, Lee KH, Suh KS, Yu BC, Jang MS

  • KMID: 2509668
  • Korean J Dermatol.
  • 2020 Dec;58(10):662-668.
Background: The etiology and pathogenesis of lichen planus (LP) are not fully understood. Several studies have reported varying prevalence of anti-hepatitis C virus antibody (anti-HCV Ab) in LP. The relationship...
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Ethnobotany, Phytochemistry, and Pharmacology of Angelica decursiva Fr. et Sav.

Ali MY, Seong SH, Jannat S, Jung HA, Choi JS

Angelica decursiva Fr. et Sav. (Umbelliferae) has traditionally been used to treat different diseases due to its antitussive, analgesic, and antipyretic activities. It is also a remedy for thick phlegm,...
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Vitiligo with Leukotrichia Following Topical Diphenylcyclopropenone Immunotherapy for Acute Diffuse and Total Alopecia

Park JB, Seong SH, Jang JY, Yang MH, Kim JH, Suh KS, Sim WY, Jang MS

Leukotrichia is defined as depigmentation of hair within vitiligo macules and is considered indicative of the destruction of the melanocyte reservoir within the hair follicle. A 15-year-old woman with acute...
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Isolation and Quantitative Analysis of BACE1 Inhibitory Compounds from Cirsium maackii Flower

Bhatarrai , Seong SH, Jung HA, Choi JS

The purpose of our study was to evaluate anti-AD potential of Cirsium maackii flowers. MeOH extract, CH2Cl2, EtOAc, and n-BuOH fraction of this flower notably inhibited BACE1 (ICâ‚…â‚€ = 76.47...
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Anti-inflammatory Potential of Artemisia capillaris and Its Constituents in LPS-induced RAW264.7 Cells

Abdul QA, Seong SH, Ahn BR, Islam MN, Jung HA, Choi JS

Artemisia capillaris has been widely used as an alternative therapy for treating obesity and atopic dermatitis. It has been used as a hepatoprotactant. It is also used for ameliorating inflammatory...
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Isolation of Flavonoid Glycosides with Cholinesterase Inhibition Activity and Quantification from Stachys japonica

Nugroho A, Choi JS, Seong SH, Song BM, Park KS, Park HJ

The three flavone glycosides, 4′-O-methylisoscutellarein 7-O-(6‴-O-acetyl)-β-D-allopyranosyl(1→2)-β-D-glucopyranoside (1), isoscutellarein 7-O-(6‴-O-acetyl)-β-D-allopyranosyl(1→2)-β-D-glucopyranoside (3), and isoscutellarein 7-O-β-D-allopyranosyl(1→2)-β-D-glucopyranoside (4) in addition to a flavonol glycoside, kaempferol 3-O-β-D-glucopyranoside (astragalin, 2), were isolated from Stachys japonica (Lamiaceae)....
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The Abuse Potential of α-Piperidinopropiophenone (PIPP) and α-Piperidinopentiothiophenone (PIVT), Two New Synthetic Cathinones with Piperidine Ring Substituent

Botanas CJ, Yoon SS, de la Peña JB, dela Peña IJ, Kim M, Woo T, Seo JW, Jang CG, Park KT, Lee YH, Lee YS, Kim HJ, Cheong JH

A diversity of synthetic cathinones has flooded the recreational drug marketplace worldwide. This variety is often a response to legal control actions for one specific compound (e.g. methcathinone) which has...
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Evaluation of the Abuse Potential of Novel Amphetamine Derivatives with Modifications on the Amine (NBNA) and Phenyl (EDA, PMEA, 2-APN) Sites

Custodio R, Botanas CJ, Yoon SS, de la Peña JB, dela Peña IJ, Kim M, Woo T, Seo JW, Jang CG, Kwon YH, Kim NY, Lee YS, Kim HJ, Cheong JH

Recently, there has been a rise in the number of amphetamine derivatives that serve as substitutes for controlled substances (e.g. amphetamine and methamphetamine) on the global illegal drug market. These...
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HPLC analysis of Phenolic Substances and Anti-Alzheimer's Activity of Korean Quercus Species

Nugroho A, Song BM, Seong SH, Choi JS, Choi J, Choi JY, Park HJ

This study aimed to establish the quantitative method to analyze the content of peroxynitrite-scavengers belonging to polyphenols in six Korean Quercus species (Quercus mongolica, Q. dentata, Q. acutissima, Q. alienta,...
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Assessment of the Abuse Liability of Synthetic Cannabinoid Agonists JWH-030, JWH-175, and JWH-176

Tampus R, Yoon SS, de la Pena JB, Botanas CJ, Kim HJ, Seo JW, Jeong EJ, Jang CG, Cheong JH

The emergence and use of synthetic cannabinoids have greatly increased in recent years. These substances are easily dispensed over the internet and on the streets. Some synthetic cannabinoids were shown...
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Comparison of the Population Pharmacokinetics and Safety Between Please Orally Soluble Film and VIAGRA(R) in Healthy Male Volunteers

Hong T, Lee J, Jeon S, Paek J, Kim HI, Kwak SS, Park SJ, Han S, Yim DS

  • KMID: 2334542
  • J Korean Soc Clin Pharmacol Ther.
  • 2013 Jun;21(1):26-33.
BACKGROUND: The objective of this study was to compare the pharmacokinetics and safety between newly developed sildenafil (Please Orally Soluble Film) and sildenafil citrate (VIAGRA(R)) after single oral administration in...
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A Rare Case of Transformation of Childhood Myelodysplastic Syndrome to Acute Lymphoblastic Leukemia

Koh YR, Cho EH, Park SS, Park MY, Lee SM, Kim IS, Lee EY

Transformation of MDS into ALL during childhood is extremely rare. We report a rare case of an 8-yr-old girl who presented with refractory cytopenia of childhood (RCC) that transformed into...
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The effectiveness of tacrolimus and minidose methotrexate in the prevention of acute graft-versus-host disease following allogeneic hematopoietic stem cell transplantation in children: a single-center study in Korea

Park SS, Jun SE, Lim YT

BACKGROUND: Knowledge of the roles of tacrolimus and minidose methotrexate (MTX) in the prevention of acute graft-versus-host disease (aGVHD) in pediatric allogeneic hematopoietic stem cell transplantation (HSCT) is limited. We...
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Effect on Glycemic, Blood Pressure, and Lipid Control according to Education Types

Choi MJ, Yoo SH, Kim KR, Bae YM, Ahn SH, Kim SS, Min SA, Choi JS, Lee SE, Moon YJ, Rhee EJ, Park CY, Lee WY, Oh KW, Park SW, Kim SW

BACKGROUND: Diabetes self-management education and reinforcement are important for effective management of the disease. We investigated the effectiveness of interactive small-group education on glycemic, blood pressure, and lipid levels. METHODS: For...
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Spontaneous Hemoperitoneum in Patients Taking Anticoagulants

Baek JB, Seong SH, Won DY, Bae KS, Kim IY

PURPOSE: Spontaneous hemoperitoneum is not a common disease but may cause a fatal outcome. Warfarin is a coumarin anticoagulant, used widely for therapeutic and prophylactic anticoagulation. Although, it is considered...
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A Case of Infantile Hepatic Hemangioendothelioma Incidentally Detected during the Evaluation of Galactosemia

Lim RK, Byun SY, Park SS, Kim YD

  • KMID: 2144479
  • J Korean Soc Neonatol.
  • 2010 May;17(1):136-140.
Galactosemia is a group of inherited enzyme deficiencies characterized by increase in the blood galactose levels. This condition may be associated with deficiencies of galactose-1-phosphate uridyl transferase, galactokinase, or uridine...
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The Prognostic Factors and Severity Index in Fournier's Gangrene

Kim KM, Seong SH, Won DY, Ryu H, Kim IY

PURPOSE: Fournier's disease is polymicrobial necrotizing fasciitis of the perineal, perianal, or genital areas. The objective of this study was to investigate patients with Fournier's gangrene and to determine risk...
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A Case of Apert Syndrome with a P253R Mutation on FGFR2 Exon VIII

Lee YJ, Ko JM, Park SS, Cheon CK

  • KMID: 2184481
  • J Genet Med.
  • 2010 Dec;7(2):151-155.
Apert syndrome is a rare congenital anomaly characterized by craniofacial malformations and severe symmetrical syndactyly of fingers and toes. This syndrome is caused by a genetic mutation; the S253 mutation...
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