- [18F]THK5351 PET Imaging in Patients with Mild Cognitive Impairment
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Jeong HJ, Lee H, Lee SY, Seo S, Park KH, Lee YB, Shin DJ, Kang JM, Yeon BK, Kang SG, Cho J, Seong JK, Okamura N, Villemagne VL, Na DL, Noh Y
- KMID: 2506811
- J Clin Neurol.
- 2020 Apr;16(2):202-214.
- doi: 10.3988/jcn.2020.16.2.202
Background and Purpose Mild cognitive impairment (MCI) is a condition with diverse clinical outcomes and subgroups. Here we investigated the topographic distribution of tau in vivo using the positron emission tomography... -
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- A comparison of the metabolic effects of treadmill and wheel running exercise in mouse model
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Kim YJ, Kim HJ, Lee WJ, Seong JK
- KMID: 2510420
- Lab Anim Res.
- 2020 Mar;36(1):20-27.
- doi: 10.1186/s42826-019-0035-8
Aerobic exercise is well known to have a positive impact on body composition, muscle strength, and oxidative capacity. In animal model, both treadmill and wheel running exercise modalities have become... -
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- Evaluation of factors related to Anaesthesia-induced Lens opacity in experimental mice
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Lee H, Kim HK, Shin HS, Han SJ, Yoon S, Seong JK, Seo KY
- KMID: 2510418
- Lab Anim Res.
- 2020 Mar;36(1):1-10.
- doi: 10.1186/s42826-019-0031-z
To investigate conditions that cause temporal lens opacity, we tested chemical and physical factors, such as anaesthesia dose, ocular surface dryness, and infrared (IR) light exposure in anaesthetised C57BL/6 N mice.... -
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- Effect of a Single Bout of Exercise on Autophagy Regulation in Skeletal Muscle of High-Fat High-Sucrose Diet-Fed Mice
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Zhang D, Lee JH, Kwak SE, Shin HE, Zhang Y, Moon HY, Shin DM, Seong JK, Tang L, Song W
- KMID: 2459812
- J Obes Metab Syndr.
- 2019 Sep;28(3):175-185.
- doi: 10.7570/jomes.2019.28.3.175
BACKGROUND: Autophagy maintains metabolic homeostasis of muscles, and its impairment may cause muscle dysfunction. Exercise can improve muscle dysfunction induced by long-term high-fat diet. This study aimed to explore the... -
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- Welcome to Laboratory Animal Research
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Seong JK
- KMID: 2456053
- Lab Anim Res.
- 2019 Jun;35(1):1-1.
- doi: 10.1186/s42826-019-0005-1
No abstract available. -
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- TarGo: network based target gene selection system for human disease related mouse models
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Hyung D, Mallon AM, Kyung DS, Cho SY, Seong JK
- KMID: 2470013
- Lab Anim Res.
- 2019 Dec;35(4):165-171.
- doi: 10.1186/s42826-019-0023-z
Genetically engineered mouse models are used in high-throughput phenotyping screens to understand genotype-phenotype associations and their relevance to human diseases. However, not all mutant mouse lines with detectable phenotypes are... -
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- Efficacy and Safety of UI05MSP015CT in Functional Dyspepsia: A Randomized, Controlled Trial
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Yoon H, Lee DH, Lee YH, Jeong JC, Lee ST, Choi MG, Jeon SW, Shim KN, Baik GH, Kim JG, Moon JS, Sung IK, Lee SK, Rhee PL, Jung HY, Lee BE, Kim HS, Kim SG, Lee KM, Seong JK, Jang JS, Park JJ
- KMID: 2424079
- Gut Liver.
- 2018 Sep;12(5):516-522.
- doi: 10.5009/gnl17416
BACKGROUND/AIMS: To evaluate the efficacy and safety of a controlled release, once-daily formulation of mosapride (UI05MSP015CT) in patients with functional dyspepsia (FD). METHODS: Patients with FD were randomly assigned (1:1) to... -
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- Ensuring reproducibility and ethics in animal experiments reporting in Korea using the ARRIVE guideline
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Nam MH, Chun MS, Seong JK, Kim HG
- KMID: 2430881
- Lab Anim Res.
- 2018 Mar;34(1):11-19.
- doi: 10.5625/lar.2018.34.1.11
The aim of this study is to evaluate the reporting quality of animal experiments in Korea using the Animals in Research: Reporting In Vivo Experiments (ARRIVE) guideline developed in 2010... -
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- Machine learning in biomedical engineering
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Park C, Took CC, Seong JK
- KMID: 2439530
- Biomed Eng Lett.
- 2018 Feb;8(1):1-3.
- doi: 10.1007/s13534-018-0058-3
No abstract available. -
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- Changes of myelin basic protein in the hippocampus of an animal model of type 2 diabetes
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Nam SM, Kwon HJ, Kim W, Kim JW, Hahn KR, Jung HY, Kim DW, Yoo DY, Seong JK, Hwang IK, Yoon YS
- KMID: 2459293
- Lab Anim Res.
- 2018 Dec;34(4):176-184.
- doi: 10.5625/lar.2018.34.4.176
In this study, we observed chronological changes in the immunoreactivity and expression level of myelin basic protein (MBP), one of the most abundant proteins in the central nervous system, in... -
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- Effects of aluminum on the reduction of neural stem cells, proliferating cells, and differentiating neuroblasts in the dentate gyrus of D-galactose-treated mice via increasing oxidative stress
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Nam SM, Kim JW, Yoo DY, Kim W, Jung HY, Choi JH, Hwang IK, Seong JK, Yoon YS
- KMID: 2413161
- J Vet Sci.
- 2016 Jun;17(2):127-136.
- doi: 10.4142/jvs.2016.17.2.127
Aluminum (Al) accumulation increases with aging, and long-term exposure to Al is regarded as a risk factor for Alzheimer's disease. In this study, we investigated the effects of Al and/or... -
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- Reduction of adult hippocampal neurogenesis is amplified by aluminum exposure in a model of type 2 diabetes
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Nam SM, Kim JW, Yoo DY, Jung HY, Choi JH, Hwang IK, Seong JK, Yoon YS
- KMID: 2363330
- J Vet Sci.
- 2016 Mar;17(1):13-20.
- doi: 10.4142/jvs.2016.17.1.13
In this study, we investigated the effects of chronic aluminum (Al) exposure for 10 weeks on cell proliferation and neuroblast differentiation in the hippocampus of type 2 diabetic rats. Six-week-old... -
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- Postnatal changes in glucose transporter 3 expression in the dentate gyrus of the C57BL/6 mouse model
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Jung HY, Yim HS, Yoo DY, Kim JW, Chung JY, Seong JK, Yoon YS, Kim DW, Hwang IK
- KMID: 2312148
- Lab Anim Res.
- 2016 Mar;32(1):1-7.
- doi: 10.5625/lar.2016.32.1.1
In this study, we observed the ontogenetic changes in glucose transporter 3 (GLUT3) immunoreactivity, a major neuronal GLUT, in the dentate gyrus of mouse brains at various ages: postnatal day... -
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- A Case of Endoscopically Complete Remission of Esophageal Neuroendocrine Tumors by Concurrent Chemoradiation Therapy
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Kim MH, Jeong HY, Seong JK, Moon HS, Kang SH, Kim DK
- KMID: 2383504
- Korean J Gastroenterol.
- 2016 Nov;68(5):265-269.
- doi: 10.4166/kjg.2016.68.5.265
Neuroendocrine tumors (NETs) of the esophagus are extremely rare, aggressive and have a poor prognosis. Combined therapy using chemotherapy, radiotherapy and/or surgery appear effective. Here, we present a patient with... -
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- Air assisted lamellar keratectomy for the corneal haze model
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Kim S, Park YW, Lee E, Park SW, Park S, Kim JW, Seong JK, Seo K
- KMID: 2344308
- J Vet Sci.
- 2015 Sep;16(3):349-356.
- doi: 10.4142/jvs.2015.16.3.349
To standardize the corneal haze model in the resection depth and size for efficient corneal haze development, air assisted lamellar keratectomy was performed. The ex vivo porcine corneas were categorized... -
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- Comparison of pharmacological and genetic inhibition of cyclooxygenase-2: effects on adult neurogenesis in the hippocampal dentate gyrus
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Nam SM, Kim JW, Yoo DY, Choi JH, Kim W, Jung HY, Won MH, Hwang IK, Seong JK, Yoon YS
- KMID: 2344296
- J Vet Sci.
- 2015 Sep;16(3):245-251.
- doi: 10.4142/jvs.2015.16.3.245
Inducible cyclooxygenase-2 (COX-2) has received much attention because of its role in neuro-inflammation and synaptic plasticity. Even though COX-2 levels are high in healthy animals, the function of this factor... -
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- Treadmill exercise prevents diabetes-induced increases in lipid peroxidation and decreases in Cu,Zn-superoxide dismutase levels in the hippocampus of Zucker diabetic fatty rats
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Kim JW, Chae J, Nam SM, Kim YN, Yoo DY, Choi JH, Jung HY, Song W, Hwang IK, Seong JK, Yoon YS
- KMID: 2160815
- J Vet Sci.
- 2015 Mar;16(1):11-16.
- doi: 10.4142/jvs.2015.16.1.11
In the present study, we investigated the effects of treadmill exercise on lipid peroxidation and Cu,Zn-superoxide dismutase (SOD1) levels in the hippocampus of Zucker diabetic fatty (ZDF) rats and lean... -
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- Nephrotic Syndrome Related to Early Gastric Cancer
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Kim GD, Kim HJ, Shin HJ, Joo JS, Kim JS, Moon HS, Kang SH, Seong JK, Jeong HY, Song KS
- KMID: 2149706
- Korean J Helicobacter Up Gastrointest Res.
- 2015 Dec;15(4):249-253.
- doi: 10.7704/kjhugr.2015.15.4.249
Nephrotic syndrome results in a prolonged, heavy increase in glomerular permeability to proteins. Nephrotic syndrome caused by malignant neoplasms accounts for 7.9% to 10.9%. Nephrotic syndrome can improve following resection... -
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- Helicobacter apodemus sp. nov., a new Helicobacter species identified from the gastrointestinal tract of striped field mice in Korea
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Jeon WJ, Dong HJ, Shin JH, Kim IY, Ho H, Oh SH, Yoon YM, Choi YK, Suh JG, Nam KH, Kim HC, Cho S, Seong JK
- KMID: 2133630
- J Vet Sci.
- 2015 Dec;16(4):475-481.
- doi: 10.4142/jvs.2015.16.4.475
A novel Helicobacter species was identified from the gastrointestinal tract of the Korean striped field mouse (Apodemus agrarius). Biochemical testing, ultrastructure characterization, and 16S rRNA gene sequence analysis suggested that... -
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- The Preventive Effects of 8 Weeks of Resistance Training on Glucose Tolerance and Muscle Fiber Type Composition in Zucker Rats
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Kim JY, Choi MJ, So B, Kim HJ, Seong JK, Song W
- KMID: 2174016
- Diabetes Metab J.
- 2015 Oct;39(5):424-433.
- doi: 10.4093/dmj.2015.39.5.424
BACKGROUND: We investigated the therapeutic effects of resistance training on Zucker rats before and after the onset of diabetes to understand the importance of the timing of exercise intervention. We... -
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