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A Case of Sarcoidosis Associated with Non-tuberculous Mycobacteria

Seok SH, Shin JU, Kim HJ, Lee HJ, Yoon MS, Kim DH

  • KMID: 2505563
  • Korean J Dermatol.
  • 2020 Aug;58(7):483-486.
Sarcoidosis is a multisystem granulomatous disease of unknown etiology. A range of factors including tuberculous infection, beryllium exposure, and cold climate have been implicated in the pathogenesis of the condition....
Effects of paternal age on human embryo development in in vitro fertilization with preimplantation genetic screening

Kim MK, Park JK, Jeon Y, Seok SH, Chang EM, Lee WS

OBJECTIVE: As paternal age increases, the quality of sperm decreases due to increased DNA fragmentation and aneuploidy. Higher levels of structural chromosomal aberrations in the gametes ultimately decrease both the...
Fracture analysis of wild mammals in South Korea

This study was conducted to evaluate and analyze fractures types in wild mammals in Korea. Wild mammals treated at 3 wildlife centers in Korea were included. Of the 63 cases...
Fasiglifam (TAK-875), a G Protein-Coupled Receptor 40 (GPR40) Agonist, May Induce Hepatotoxicity through Reactive Oxygen Species Generation in a GPR40-Dependent Manner

Kim M, Gu GJ, Koh YS, Lee SH, Na YR, Seok SH, Lim KM

Fasiglifam (TAK-875) a G-protein coupled receptor 40 (GPR40) agonist, significantly improves hyperglycemia without hypoglycemia and weight gain, the major side effects of conventional anti-diabetics. Unfortunately, during multi-center Phase 3 clinical...
Diagnostic laparoscopy in a leopard cat (Prionailurus bengalensis) with intercostal abdominal hernia and hepatic lipidosis

Seok SH, Park SJ, Lee SY, Lee HC, Yeon SC

Intercostal abdominal hernia in the 11th intercostal space was identified in a leopard cat. Although mild leukopenia was found in laboratory examinations, no remarkable abnormality was revealed in medical imaging....
Zebrafish Larvae Model of Dilated Cardiomyopathy Induced by Terfenadine

Gu G, Na Y, Chung H, Seok SH, Lee HY

BACKGROUND AND OBJECTIVES: Dilated cardiomyopathy can be the end-stage of severe cardiac disorders and directly affects the cardiac muscle, inducing cardiomegaly and heart failure (HF). Although a wide variety of...
Factors Affecting Sleep Quality in Women with Cancer Undergoing Radiotherapy

Seok SH, Jun SE

PURPOSE: The purpose of this study was to investigate the severity of subjective sleep quality and factors related to sleep disturbances in breast and gynecologic cancer patients undergoing radiotherapy. METHODS: Ninety...
Epidemiological Characteristics and Risk Factors of Dengue Infection in Korean Travelers

Je S, Bae W, Kim J, Seok SH, Hwang ES

Dengue viral infection has rapidly spread around the world in recent decades. In Korea, autochthonous cases of dengue fever have not been confirmed yet. However, imported dengue cases have been...
The Preparedness for Re-emerged and Emerging Infectious Diseases: A Lesson Through Outbreak of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in South Korea

Je S, Bae W, Kim J, Seok SH, Hwang ES

The Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe acute respiratory disease and systemic dysfunction that may eventually lead to the death of the patients. After MERS-CoV was first diagnosed...
Detection of Corynebacterium bovis infection in athymic nude mice from a research animal facility in Korea

Kim TH, Kim DS, Han JH, Chang SN, Kim KS, Seok SH, Kim DJ, Park JH, Park JH

Corynebacterium (C.) bovis infection in nude mice causes hyperkeratosis and weight loss and has been reported worldwide but not in Korea. In 2011, nude mice from an animal facility in...
Effects of dietary high fat on prostate intraepithelial neoplasia in TRAMP mice

Park SH, Chang SN, Baek MW, Kim DJ, Na YR, Seok SH, Lee BH, Kim KS, Park JH

  • KMID: 2312102
  • Lab Anim Res.
  • 2013 Mar;29(1):39-47.
Increased fat intake is known to be a major cause of prostate cancer. In this study, we investigated the effect of dietary high fat on prostate intraepithelial neoplasia using transgenic...
Ethical Guidelines for Use of Experimental Animals in Biomedical Research

Cho A, Seok SH

Increasing concerns on animal welfare, the discussion about the necessity and the ethical acceptability of animal experiments is getting important. In this article, we describe ethical issues between the benefits...
Adiaspiromycosis of an Apodemus agrarius captured wild rodent in Korea

Kim TH, Han JH, Chang SN, Kim DS, Abdelkader TS, Seok SH, Park JH, Oh HS, Kim JT, Lee BH, Shin JH, Kim JH, Kim JM, Park JH

  • KMID: 2312095
  • Lab Anim Res.
  • 2012 Mar;28(1):67-69.
Adiaspiromycosis is caused by pulmonary infection with Emmonsia. Inhalated spores of Emmonsia cause asymptomatic infection to necrogranulomatous pneumonia, depending on the burden of adiaspore and host immunity. For disease monitoring...
Detection of sarcocystic infection in a wild rodent (Apodemus agrarius chejuensis) captured on Jeju island

Kim TH, Han JH, Chang SN, Kim DS, Abdelkader TS, Seok SH, Park JH, Oh HS, Kim JT, Lee BH, Shin JH, Kim JH, Kim JM, Park JH

Sarcocystis spp is a causative agent of sarcocystosis. They have a characteristic life cycle infecting both prey and predator. Sarcocystis can cause myositis, atrophy of the adjacent cells and abortion...
Production of specific antibodies against SARS-coronavirus nucleocapsid protein without cross reactivity with human coronaviruses 229E and OC43

Lee HK, Lee BH, Seok SH, Baek MW, Lee HY, Kim DJ, Na YR, Noh KJ, Park SH, Kumar DN, Kariwa H, Nakauchi M, Heo SJ, Park JH

Severe acute respiratory syndrome (SARS) is a life-threatening disease for which accurate diagnosis is essential. Although many tools have been developed for the diagnosis of SARS, false-positive reactions in negative...
NaCl plus chitosan as a dietary salt to prevent the development of hypertension in spontaneously hypertensive rats

Park SH, Dutta NK, Baek MW, Kim DJ, Na YR, Seok SH, Lee BH, Cho JE, Cho GS, Park JH

The effect of NaCl plus 3% chitosan on the systolic blood pressure of spontaneously hypertensive rats (SHR) were evaluated and compared with NaCl plus KCl (NaCl, 49.36% + KCl 49.36%)...
Epidermal Growth Factor Receptor Expression of Non-small Cell Carcinoma and Its Relationship with Genomic Mutation

Seok SH, Kim MJ

  • KMID: 1163256
  • Korean J Pathol.
  • 2008 Apr;42(2):94-99.
BACKGROUND: It has recently been clarified that epidermal growth factor receptor (EGFR), which is a receptor tyrosine kinase of the erbB family, is abnormally activated in non-small cell lung...
Protective and therapeutic effects of an extract mixture of alder tree, labiate herb, milk thistle green bean-rice bran fermentation, and turnip against ethanol-induced toxicity in the rat

Baek MW, Seok SH, Lee HY, Kim DJ, Lee BH, Ahn YT, Lim KS, Huh CS, Park JH

An herbal extract mixture and yogurt added to the herbal extract mixture were tested for their protective and therapeutic effects on ethanol-induced liver injury. The herbal extract mixture, yogurt and...
Prognosis of Gastrointestinal Stromal Tumors Arising in the Stomach and Small Intestine: A Retrospective Study of 126 Cases from a Single Institution

Seok SH, Kim JM, Bae JM, Kim SW, Kim SW, Song SK, Bae YK

  • KMID: 1163175
  • Korean J Pathol.
  • 2008 Dec;42(6):335-343.
BACKGROUND: Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor in the gastrointestinal tract. As all GISTs have the potential for aggressive clinical behavior, the guidelines for defining the...
In vivo alternative testing with zebrafish in ecotoxicology

Seok SH, Baek MW, Lee HY, Kim DJ, Na YR, Noh KJ, Park SH, Lee HK, Lee BH, Park JH

Although rodents have previously been used in ecotoxicological studies, they are expensive, time-consuming, and are limited by strict legal restrictions. The present study used a zebrafish (Danio rerio) model and...

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