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Selection of analgesics for the management of acute and postoperative dental pain:a mini-review

Kim SJ, Seo JT

Pain management is an important part of dental practice, and dentists frequently prescribe analgesics to improve clinical outcomes. Dentists should be aware of the pharmacological characteristics of the analgesics commonly...
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Do Kimchi and Cheonggukjang Probiotics as a Functional Food Improve Androgenetic Alopecia? A Clinical Pilot Study

Park DW, Lee HS, Shim MS, Yum KJ, Seo JT

PURPOSE: Probiotic supplementation demonstrates beneficial effects on serum lipid profiles. We hypothesized that probiotics could benefit patients presenting with alopecia, secondary to improved blood flow to the scalp. MATERIALS AND METHODS:...
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Biological characteristics of osteoporosis drugs: the effect of osteoblast–osteoclast coupling

Kim SJ, Moon SJ, Seo JT

Osteoporosis is a common disease characterized by bone mass reduction, leading to an increased risk of bone fracture, and it is caused by an imbalance of osteoblastic bone formation and...
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Sex Differences in Lower Urinary Tract Symptoms in Older Korean Adults Living in Rural Areas: Prevalence, Quality of Life, and Associated Factors

Park J, Kim ES, Lee YJ, Lee HS, Seo JT

PURPOSE: Urinary incontinence (UI) is associated with nursing home admission, functional decline, and risk of death among community-dwelling older adults. Little information, however, is available on sex differences in lower...
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Abnormal Human Sperm Parameters Contribute to Sperm DNA Fragmentation in Men with Varicocele

Park YS, Lee SH, Choi HW, Lee HS, Lee JS, Seo JT

PURPOSE: This study was performed to evaluate and compare threshold sperm parameters and sperm DNA fragmentation index (DFI), and further analyzed whether sperm DFI could be predicted from sperm parameters...
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Legal issues and recommendations for public sperm bank

Seo JT

Approximately 15% of couples hoping to conceive are infertile. Male factor infertility is the only cause in 40% of those couples. Approximately 20% of men with infertility have azoospermia. Of...
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Clinical Efficacy of Solifenacin in the Management of Diabetes Mellitus-Associated Versus Idiopathic Overactive Bladder Symptoms: A Multicenter Prospective Study

Choi H, Bae JH, Oh CY, Jeong SJ, Ko WJ, Choi JB, Seo JT, Lee DH, Kim JC, Lee KW, Kim YH

PURPOSE: To compare the clinical efficacy of anticholinergics for managing diabetes mellitus-associated overactive bladder (DM OAB) versus idiopathic overactive bladder (OAB) in Korean women. METHODS: We conducted a multicenter, prospective, parallel-group,...
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Efficacy of an Alpha-Blocker for the Treatment of Nonneurogenic Voiding Dysfunction in Women: An 8-Week, Randomized, Double-Blind, Placebo-Controlled Trial

Lee YS, Lee KS, Choo MS, Kim JC, Lee JG, Seo JT, Lee JZ, Lee JY, Oh SJ, Na YG

PURPOSE: To evaluate the efficacy of an alpha-1 adrenergic receptor (α1-AR) blocker for the treatment of female voiding dysfunction (FVD) through a pressure-flow study. METHODS: This was a randomized, double-blind, placebo-controlled...
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Effects of infections with five sexually transmitted pathogens on sperm quality

Kim SJ, Paik DJ, Lee JS, Lee HS, Seo JT, Jeong MS, Lee JH, Park DW, Han S, Lee YK, Lee KH, Lee IH, So KA, Kim SA, Kim J, Kim TJ

OBJECTIVE: This study investigated the prevalence of infections with human papillomavirus, Chlamydia trachomatis, Ureaplasma urealyticum, Mycoplasma hominis, and Mycoplasma genitalium in the semen of Korean infertile couples and their associations...
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Hypogonadism Makes Dyslipidemia in Klinefelter's Syndrome

Lee HS, Park CW, Lee JS, Seo JT

Klinefelter's syndrome (KS) is a genetic syndrome that presents with hypogonadism and is associated with metabolic syndrome. Patients demonstrating hypogonadism show a greater prevalence of metabolic syndrome due to changes...
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Development of a Robotic Colonoscopic Manipulation System, Using Haptic Feedback Algorithm

Woo J, Choi JH, Seo JT, Kim TI, Yi BJ

PURPOSE: Colonoscopy is one of the most effective diagnostic and therapeutic tools for colorectal diseases. We aim to propose a master-slave robotic colonoscopy that is controllable in remote site using...
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Serum and seminal plasma insulin-like growth factor-1 in male infertility

Lee HS, Park YS, Lee JS, Seo JT

OBJECTIVE: Growth hormone and its mediator, insulin-like growth factor-1 (IGF-1), have been suggested to exert gonadotropic actions in both humans and animals. The present study was conducted to assess the...
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Three cases of rare SRY-negative 46,XX testicular disorder of sexual development with complete masculinization and a review of the literature

Lee BY, Lee SY, Lee YW, Kim SY, Kim JW, Ryu HM, Lee JS, Park SY, Seo JT

PURPOSE: To identify the clinical characteristics of SRY-negative male patients and genes related to male sex reversal, we performed a retrospective study using cases of 46,XX testicular disorders of sex...
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Reactive Oxygen Species are Involved in Y-27632-induced Neurite Outgrowth in PC12 Cells

Park SY, Moon SA, An JM, Kim DS, Seo JT

Inhibition of Rho-associated coiled coil-containing kinase (ROCK) has been reported to promote differentiation of neuronal cells. Here, we examined the effect of Y-27632, a ROCK inhibitor, on the outgrowth of...
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Effects of maternal age on embryo quality and pregnancy outcomes using testicular sperm with intracytoplasmic sperm injection

Choi HW, Park YS, Lee SH, Lim CK, Seo JT, Yang KM

OBJECTIVE: The aim of this study was to evaluate the influence of maternal age on fertilization, embryo quality, and clinical pregnancy in patients undergoing intracytoplasmic sperm injection (ICSI) using testicular...
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Treatment of Leukocytospermia in Male Infertility: A Systematic Review

Jung JH, Kim MH, Kim J, Baik SK, Koh SB, Park HJ, Seo JT

Male factors account for 20% to 50% of infertility cases, and infection in the genitourinary tract may play a contributing role in up to 15% of male infertility. Leukocytospermia is...
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Staurosporine Induces ROS-Mediated Process Formation in Human Gingival Fibroblasts and Rat Cortical Astrocytes

Lee HG, Kim DS, Moon SA, Kang JW, Seo JT

In the present study, we investigated the effect of staurosporine on the formation of cellular processes in human gingival fibroblasts and rat astrocytes. Staurosporine caused a rapid induction of process...
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Urinary incontinence and overactive bladder

Lee HS, Seo JT

The overactive bladder (OAB) and incontinence may occur at any age but are more common in the elderly. These lower urinary tract symptoms are associated with reduced quality of life...
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Observation of sperm-head vacuoles and sperm morphology under light microscope

Park YS, Park S, Ko DS, Park DW, Seo JT, Yang KM

OBJECTIVE: The presence of sperm-head vacuoles has been suspected to be deleterious to the outcomes of assisted reproductive technology (ART). It is difficult to accurately distinguish morphologically abnormal sperm with...
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Empirical medical therapy in idiopathic male infertility: Promise or panacea?

Jung JH, Seo JT

Male factors account for 20%-50% of cases of infertility and in 25% of cases, the etiology of male infertility is unknown. Effective treatments are well-established for hypogonadotropic hypogonadism, male accessory...
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