- Transcriptional profiling of mouse cavernous pericytes under high-glucose conditions: Implications for diabetic angiopathy
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Yin GN, Wu J, Cui Y, Lin C, Shi L, Gao ZL, Suh JK, Ryu JK, Jin HR
- KMID: 2509866
- Investig Clin Urol.
- 2021 Jan;62(1):100-110.
- doi: 10.4111/icu.20200272
Purpose: Penile erection requires integrative interactions between vascular endothelial cells, pericytes, smooth muscle cells, and autonomic nerves. Furthermore, the importance of the role played by pericytes in the pathogenesis of... -
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- Gene expression profiling of mouse cavernous endothelial cells for diagnostic targets in diabetes-induced erectile dysfunction
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Yin GN, Ock J, Choi MJ, Limanjaya A, Ghatak K, Song KM, Kwon MH, Suh JK, Ryu JK
- KMID: 2509862
- Investig Clin Urol.
- 2021 Jan;62(1):90-99.
- doi: 10.4111/icu.20200119
Purpose: To investigate potential target genes associated with the diabetic condition in mouse cavernous endothelial cells (MCECs) for the treatment of diabetes-induced erectile dysfunction (ED). Materials and Methods: Mouse cavernous tissue... -
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- Three-Dimensional Reconstruction of Neurovascular Network in Whole Mount Preparations and ThickCut Transverse Sections of Mouse Urinary Bladder
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Nguyen NM, Song KM, Choi MJ, Ghatak K, Limanjaya A, Kwon MH, Chung DY, Ock J, Yin GN, Park CS, Suh JK, Ryu JK
- KMID: 2509589
- World J Mens Health.
- 2021 Jan;39(1):131-138.
- doi: 10.5534/wjmh.190089
Purpose: Proper functional and structural integrity of nervous and vascular system in urinary bladder plays an important role in normal bladder function and the disruption of these structures is known... -
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- Early efficacy and safety of statin therapy in Korean patients with hypercholesterolemia: Daegu and Gyeongbuk Statin Registry
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Bae HJ, Cho YK, Park HS, Yoon HJ, Kim H, Han S, Hur SH, Kim YN, Kim KB, Ryu JK, Nah DY, Nam CW
- KMID: 2502020
- Korean J Intern Med.
- 2020 Mar;35(2):342-350.
- doi: 10.3904/kjim.2018.272
Background/Aims: To date, prospective data are limited on efficacy and safety profiles of statin therapy in Korean hypercholesterolemic patients. Hence, the aim of this study was to evaluate the practice... -
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- Selonsertib Inhibits Liver Fibrosis via Downregulation of ASK1/ MAPK Pathway of Hepatic Stellate Cells
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Yoon YC, Fang Z, Lee JE, Park JH, Ryu JK, Jung KH, Hong SS
- KMID: 2508207
- Biomol Ther.
- 2020 Nov;28(6):527-536.
- doi: 10.4062/biomolther.2020.016
Liver fibrosis constitutes a significant health problem worldwide due to its rapidly increasing prevalence and the absence of specific and effective treatments. Growing evidence suggests that apoptosis-signal regulating kinase 1... -
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- Vactosertib, a Novel, Orally Bioavailable Activin Receptor-Like Kinase 5 Inhibitor, Promotes Regression of Fibrotic Plaques in a Rat Model of Peyronie’s Disease
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Song KM, Chung DY, Choi MJ, Ghatak K, Nhat Minh N, Limanjaya A, Kwon MH, Ock J, Yin GN, Kim DK, Ryu JK, Suh JK
- KMID: 2506420
- World J Mens Health.
- 2020 Oct;38(4):552-563.
- doi: 10.5534/wjmh.190071
Purpose: To examine the therapeutic effect of Vactosertib, a small molecule inhibitor of transforming growth factor-β (TGF-β) type I receptor (activin receptor-like kinase-5, ALK5), in an experimental model of Peyronie’s... -
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- A Simple and Nonenzymatic Method to Isolate Human Corpus Cavernosum Endothelial Cells and Pericytes for the Study of Erectile Dysfunction
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Yin GN, Ock J, Choi MJ, Song KM, Ghatak K, Minh NN, Kwon MH, Seong DH, Jin HR, Ryu JK, Suh JK
- KMID: 2465417
- World J Mens Health.
- 2020 Jan;38(1):123-131.
- doi: 10.5534/wjmh.180091
PURPOSE: To establish a simple and nonenzymatic technique to isolate endothelial cells (ECs) and pericytes from human corpus cavernosum tissue and to evaluate the angiogenic ability of the human cavernous... -
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- Duodenal Stricture due to Necrotizing Pancreatitis following Endoscopic Ultrasound-Guided Ethanol Ablation of a Pancreatic Cyst: A Case Report
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Chun JW, Lee SH, Choi JH, Paik WH, Ryu JK, Kim YT
- KMID: 2464675
- Clin Endosc.
- 2019 Sep;52(5):510-515.
- doi: 10.5946/ce.2018.191
The frequency of incidental detection of pancreatic cystic lesions (PCLs) is increasing because of the frequent use of cross-sectional imaging. The appropriate treatment for PCLs is challenging, and endoscopic ultrasound-guided... -
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- Effectiveness and Safety of Zotarolimus-Eluting Stent (Resoluteâ„¢ Integrity) in Patients with Diffuse Long Coronary Artery Disease
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Park KH, Ahn Y, Koh YY, Ki YJ, Kim SS, Kim HK, Choi DH, Hong YJ, Hwang JY, Kim DH, Rhew JY, Ryu JK, Park JS, Park TH, Yang TH, Oh SK, Lee BR, Lee SU, Lee SG, Chun KJ, Cho JH, Cha KS, Chae JK, Hur SH, Hwang SH, Park HS, Kim DI
- KMID: 2456865
- Korean Circ J.
- 2019 Aug;49(8):709-720.
- doi: 10.4070/kcj.2019.0018
BACKGROUND AND OBJECTIVES: Diffuse long coronary artery disease (DLCAD) still has unfavorable clinical outcomes after successful percutaneous coronary intervention (PCI). Therefore, we aimed to evaluate the effectiveness and safety of... -
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- Complete Remission of Metastatic Duodenal Neuroendocrine Carcinoma Treated with Chemotherapy and Surgical Resection
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Won JH, Ryu JK
- KMID: 2455076
- Korean J Pancreas Biliary Tract.
- 2019 Jul;24(3):121-126.
- doi: 10.15279/kpba.2019.24.3.121
A 57-year-old male with periampullary duodenal mass was diagnosed as grade 3 duodenal neuroendocrine carcinoma with multiple liver metastasis. After nine cycles of cisplatin and etoposide, abdominal computed tomography (CT)... -
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- Natural Course and Risk of Cholangiocarcinoma in Patients with Recurrent Pyogenic Cholangitis: A Retrospective Cohort Study
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You MS, Lee SH, Kang J, Choi YH, Choi JH, Shin BS, Huh G, Paik WH, Ryu JK, Kim YT, Jang DK, Lee JK
- KMID: 2448378
- Gut Liver.
- 2019 May;13(3):373-379.
- doi: 10.5009/gnl18339
BACKGROUND/AIMS: Recurrent pyogenic cholangitis (RPC) is a chronic progressive disease frequently accompanied by cholangiocarcinoma (CCA). This study aimed to investigate the natural course of RPC and identify factors associated with... -
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- Two Cases of Unresectable Pancreatic Cancer Treated with Neoadjuvant Chemotherapy and Surgical Resection
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Huh G, Chun JW, You MS, Paik WH, Lee SH, Kim YT, Ryu JK
- KMID: 2470444
- J Dig Cancer Rep.
- 2019 Dec;7(2):61-64.
- doi: 10.0000/jdcr.2019.7.2.61
We report two cases of patients with unresectable pancreatic cancer treated with neoadjuvant chemotherapy and surgical resection. In the first case, main mass was located at the neck of the... -
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- GABA-enriched fermented Laminaria japonica improves cognitive impairment and neuroplasticity in scopolamine- and ethanol-induced dementia model mice
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Reid SN, Ryu JK, Kim Y, Jeon BH
- KMID: 2442293
- Nutr Res Pract.
- 2018 Jun;12(3):199-207.
- doi: 10.4162/nrp.2018.12.3.199
BACKGROUND/OBJECTIVES: Fermented Laminaria japonica (FL), a type sea tangle used as a functional food ingredient, has been reported to possess cognitive improving properties that may aid in the treatment of... -
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- Silencing Histone Deacetylase 7 Alleviates Transforming Growth Factor-β1-Induced Profibrotic Responses in Fibroblasts Derived from Peyronie's Plaque
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Kang DH, Yin GN, Choi MJ, Song KM, Ghatak K, Minh NN, Kwon MH, Seong DH, Ryu JK, Suh JK
- KMID: 2419312
- World J Mens Health.
- 2018 May;36(2):139-146.
- doi: 10.5534/wjmh.170005
PURPOSE: Epigenetic modifications, such as histone acetylation/deacetylation and DNA methylation, play a crucial role in the pathogenesis of inflammatory disorders and fibrotic diseases. The aim of this study was to... -
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- Efficacy of Nab-Paclitaxel Plus Gemcitabine and Prognostic Value of Peripheral Neuropathy in Patients with Metastatic Pancreatic Cancer
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You MS, Ryu JK, Choi YH, Choi JH, Huh G, Paik WH, Lee SH, Kim YT
- KMID: 2427464
- Gut Liver.
- 2018 Nov;12(6):728-735.
- doi: 10.5009/gnl18220
BACKGROUND/AIMS: The combination of nab-paclitaxel and gemcitabine (nab-P/Gem) is widely used for treating meta-static pancreatic cancer (MPC). We aimed to evaluate the therapeutic outcomes and prognostic role of treatment-related peripheral... -
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- Prospective Multicenter Study of the Challenges Inherent in Using Large Cell-Type Stents for Bilateral Stent-in-Stent Placement in Patients with Inoperable Malignant Hilar Biliary Obstruction
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Yang MJ, Kim JH, Hwang JC, Yoo BM, Lee SH, Ryu JK, Kim YT, Woo SM, Lee WJ, Jeong S, Lee DH
- KMID: 2427463
- Gut Liver.
- 2018 Nov;12(6):722-727.
- doi: 10.5009/gnl17468
BACKGROUND/AIMS: Although endoscopic bilateral stent-in-stent placement is challenging, many recent studies have reported promising outcomes regarding technical success and endoscopic re-intervention. This study aimed to evaluate the technical accessibility of... -
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- Ultrasonographic features of pure ductal carcinoma in situ of the breast: correlations with pathologic features and biological markers
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Cha H, Chang YW, Lee EJ, Hwang JY, Kim HJ, Lee EH, Ryu JK
- KMID: 2422357
- Ultrasonography.
- 2018 Oct;37(4):307-314.
- doi: 10.14366/usg.17039
PURPOSE: The purpose of this study was to evaluate the ultrasonographic features of pure ductal carcinoma in situ (DCIS) of the breast and to evaluate the correlations of ultrasonographic features... -
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- Metastatic Gallbladder Cancer Treated with Curative Surgery after Cyclic Chemotherapy and Biliary Drainage
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You MS, Lee SH, Kang J, Choi YH, Choi JH, Paik WH, Ryu JK, Kim YT
- KMID: 2448626
- Korean J Pancreas Biliary Tract.
- 2018 Jan;23(1):41-47.
- doi: 10.15279/kpba.2018.23.1.41
Gallbladder cancer is the most common malignancy of the biliary tract and carries very poor prognosis. Surgery is an only curative modality of treatment in the gallbladder cancer. However, as... -
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- Tumor Marker Kinetics as Prognosticators in Patients with Unresectable Gallbladder Adenocarcinoma Undergoing Palliative Chemotherapy
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Lee JW, Kim YT, Lee SH, Son JH, Kang JW, Ryu JK, Jang DK, Paik WH, Lee BS
- KMID: 2404724
- Gut Liver.
- 2018 Jan;12(1):102-110.
- doi: 10.5009/gnl16588
BACKGROUND/AIMS: To determine the prognostic value of carcinoembryonic antigen (CEA) and carbohydrate antigen (CA) 19-9 in gallbladder cancer (GBC) during palliative chemotherapy. METHODS: One hundred and twenty-three patients with pathologically confirmed... -
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- Long-term Survival in Patient with Metastatic Pancreatic Neuroendocrine Tumor Treated by Variable Treatment
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Kang HC, Ryu JK, Lee SH, Kim YT
- KMID: 2448609
- Korean J Pancreas Biliary Tract.
- 2017 Jul;22(3):141-146.
- doi: 10.15279/kpba.2017.22.3.141
A 46-year-old female with abnormal radiologic finding was diagnosed with pancreatic neuroendocrine tumor and multiple hepatic metastasis. Molecular targeted therapy (everolimus) and two times of transarterial chemoembolizations (TACE) were performed... -
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