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Altered Mitochondrial Functions and Morphologies in Epithelial Cells Are Associated With Pathogenesis of Chronic Rhinosinusitis With Nasal Polyps

Yoon YH, Yeon SH, Choi MR, Jang YS, Kim JA, Oh HW, Jun X, Park SK, Heo JY, Rha KS, Kim YM

Purpose: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a complex inflammatory disease of the nasal and paranasal sinus mucosa. The disease is associated with mitochondrial dysfunction, structural changes in the...
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Nucleotide-Binding Oligomerization Domain-Like Receptor 3 Inflammasome Inhibition by MCC950 Reduces the Lipopolysaccharide-Induced Interleukin-1β in Cultured Dispersed Nasal Polyp Cells

Park SK, Han RN, Xu J, Yeon SH, Lee SB, Song K, Byun J, Rha KS, Kim YM

Background and Objectives The nucleotide-binding oligomerization domain-like receptor (NLRP) 3 is known as a member of the NLR family, and it has been confirmed that the NLRP3 inflammasome is associated...
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Long-term Breastfeeding in the Prevention of Allergic Rhinitis: Allergic Rhinitis Cohort Study for Kids (ARCO-Kids Study)

Han DH, Shin JM, An S, Kim JS, Kim DY, Moon S, Kim JS, Cho JS, Kim SW, Kim YH, Roh HJ, Shim WS, Rha KS, Kim SW, Lee SS, Kim DW, Cho KS, Yim HJ, Park SK, Rhee CS

OBJECTIVES: There is a great deal of interest in the possibility that environmental factors may influence the risk of developing allergic rhinitis (AR) in early life. We investigated the simultaneous...
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Nasality Changes With Age in Normal Korean-Speaking Adults

Xu J, Kang YA, Park SK, Yoon YH, Bai SJ, Jin YD, Kim YM, Rha KS

OBJECTIVES: This study was performed to investigate the effects of aging on nasality and the influence of age-related changes in nasal cavity volume and nasal patency on nasality. METHODS: A total...
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Role of Interleukin-10-Expressing B Cells on the Pathophysiology of Chronic Sinusitis

Park HS, Park SK, Yeon SH, Xu J, Rha KS, Kim YM

BACKGROUND AND OBJECTIVES: Many kinds of inflammatory cells and cytokines are suggested to be related with pathophysiology of chronic rhinosinusitis with nasal polyp (CRSwNP), but its mechanism is not yet...
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The Relationship between the Causative Allergens of Allergic Diseases and Environments in Korea Over a 8-Year-Period: Based on Skin Prick Test from 2006 to 2015

Park CS, Kim BY, Kim SW, Lee JH, Koo SK, Kim KS, Kim ST, Kim YD, Kim JH, Kim JK, Kim CH, Kim HJ, Kim HY, Rha KS, Roh HJ, Park DJ, Shin SH, Lim SC, Lee JH, Lee HM, Lee HG, Kim YH, Cho JH

BACKGROUND AND OBJECTIVES: The present study evaluated the results of skin prick test using 55 allergens at 20 centers in the Republic of Korea in 2006, 2010, and 2014–2015. The...
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Nasalance Changes after Endoscopic Sinus Surgery in Patients with Chronic Rhinosinusitis

Rha KS, Xu J, Park JS, Park SJ, Kang Y, Kim YM

BACKGROUND AND OBJECTIVES: The purpose of this study was to examine the effect of endoscopic sinus surgery (ESS) on nasalance in patients with chronic rhinosinusitis (CRS). SUBJECTS AND METHOD: Eighty-one CRS...
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Effect of Nasal Septoturbinoplasty on Nasality or Acoustic Parameters

Park HS, Kang YA, Xu J, Han R, Rha KS, Kim YM

BACKGROUND AND OBJECTIVES: The purpose of this study was to compare the nasality and acoustic variables of control subjects and those of patients with deviated nasal septum (DNS), preoperatively and...
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Analysis of Nasalance in Patients with Chronic Rhinosinusitis

Park SJ, Park JS, Xu J, Kang Y, Kim YM, Rha KS

BACKGROUND AND OBJECTIVES: This study was designed to compare the nasalance between chronic rhinosinusitis (CRS) patients and normal controls and to determine the correlation of nasalance with nasal volume, nasal...
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A Huge Dacryolith Presenting as a Mass of the Inferior Meatus

Seo ST, Park JS, Kim YM, Rha KS

A dacryolith is a concretion within the lacrimal drainage system. Although it may cause intermittent epiphora without inflammation, dacryoliths are often underlying contributors to recurrent or chronic dacryocystitis. It may...
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A Case of Allergic Fungal Rhinosinusitis with Concurrently Occuring Fungus Ball

Kwon KR, Park JS, Park SJ, Rha KS, Kim YM

Allergic fungal rhinosinusitis (AFRS) is a noninvasive fungal infection of the paranasal sinuses that are usually seen in young immunocompetent patients with atopy and/or asthma. Fungus balls can grow in...
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Clinical Characteristics and Expression Pattern of IL-33 and IL-25 According to Histologic Classification in Chronic Rhinosinusitis with Nasal Polyposis

Kim SH, Mo JH, Chung YJ, Xu J, Park SJ, Rha KS, Kim YM

BACKGROUND AND OBJECTIVES: Many kinds of inflammatory cells and cytokines are suggested to be related to the pathophysiology of chronic rhinosinusitis with nasal polyposis (CRSwNP), but not yet fully understood....
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Comparison of Intranasal Ciclesonide, Oral Levocetirizine, and Combination Treatment for Allergic Rhinitis

Kim CH, Kim JK, Kim HJ, Cho JH, Kim JS, Kim YD, Lee HM, Kim SW, Cho KS, Lee SH, Rhee CS, Dhong HJ, Rha KS, Yoon JH

PURPOSE: To evaluate the efficacy and safety of once-daily ciclesonide in comparison to both levocetirizine alone, and a ciclesonide/levocetirizine combination in patients with seasonal allergic rhinitis (SAR) and perennial allergic...
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Categorization and Clinicopathological Features of Chronic Rhinosinusitis With Eosinophilic Mucin in a Korean Population

Lee SH, Kim HJ, Lee JW, Yoon YH, Kim YM, Rha KS

OBJECTIVES: Chronic rhinosinusitis (CRS) with eosinophilic mucin is relatively rare in Korea. We categorized CRS patients with characteristic eosinophilic mucin into several groups and compared the groups based on their...
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Life-Threatening Upper Airway Obstruction Caused by Delayed Hematoma Occurring 8 Days Post-Thyroidectomy

Ryu KA, Seo ST, Rha KS, Koo BS

Due to modern methods, thyroid surgery is generally considered quite safe. However, post-thyroidectomy hematomas, although rare, can be life-threatening and unpredictable complications of thyroid surgery. Most postthyroidectomy hematomas occur within...
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Extramedullary Plasmacytoma of the Head and Neck

Joo JY, Park JY, Gwon GR, Koo BS, Rha KS

BACKGROUND AND OBJECTIVES: Head and neck solitary extramedullary plasmacytomas (EMP) are rare neoplasms of plasma cell origin. Literature review reveals only small numbers of reports. The objective was to review...
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A Case of Bilateral Inverted Papilloma with Malignant Transformation on One Side: Analysis of the Expression of Tumor Related Genes on Each Side Tumors

Yoon YH, Ryu KA, Yoon YH, Rha KS

Inverted papillomas are relatively rare, benign tumors of the sinonasal cavity that generate interest to many clinicians because of their high rate of recurrences, locally invasive character and malignant transformation....
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Expression Changes of Endothelin-1, Endothelin Receptor A and B in the Cochlea after Noise Exposure

Hur GM, Lyu AR, Han WK, Choi JW, Rha KS, Park YH

BACKGROUND AND OBJECTIVES: There are several evidences of reduced cochlea blood flow after noise exposure in the cochlea. However, the pathophysiology of blood flow change is still obscure, and endothelins,...
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Availability of Extended Columellar Strut Integrated with Dorsal Graft in The Patients with Loosing Nasal Septal Support

Kwak SY, Rha KS, Kim YM

  • KMID: 2132087
  • J Rhinol.
  • 2013 Nov;20(2):102-108.
BACKGROUND AND OBJECTIVES: Aesthetic and functional reconstruction of nose whose nasal septal support is deteriorated is challenging problem. The goal with this study was to evaluate our experience with 3...
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Complete Laryngotracheal Separation Following Attempted Hanging

Choi JW, Koo BS, Rha KS, Yoon YH

Laryngotracheal separation (LTS) is the most immediately life-threatening airway injury. LTS is so rare that very few otolaryngologists have experience with it. LTS is one of the diagnostic and therapeutic...
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