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A Multi-institutional Study of Prevalence and Clinicopathologic Features of Non-invasive Follicular Thyroid Neoplasm with Papillary-like Nuclear Features (NIFTP) in Korea

Seo JY, Park JH, Pyo JY, Cha YJ, Jung CK, Song DE, Kwak JJ, Park SY, Na HY, Kim JH, Seok JY, Kim HS, Hong SW

BACKGROUND: In the present multi-institutional study, the prevalence and clinicopathologic characteristics of non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) were evaluated among Korean patients who underwent thyroidectomy for...
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Preoperative Cytologic Diagnosis of Warthin-like Variant of Papillary Thyroid Carcinoma

Kim J, Lim BJ, Hong SW, Pyo JY

BACKGROUND: Warthin-like variant of papillary thyroid carcinoma (WLV-PTC) is a relatively rare variant of papillary thyroid carcinoma with favorable prognosis. However, preoperative diagnosis using fine-needle aspiration (FNA) specimens is challenging...
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The Usefulness of Immunocytochemistry of CD56 in Determining Malignancy from Indeterminate Thyroid Fine-Needle Aspiration Cytology

Cha H, Pyo JY, Hong SW

BACKGROUND: Fine-needle aspiration cytology serves as a safe, economical tool in evaluating thyroid nodules. However, about 30% of the samples are categorized as indeterminate. Hence, many immunocytochemistry markers have been...
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The Intraoperative Immunohistochemical Staining of CD56 and CK19 Improves Surgical Decision for Thyroid Follicular Lesions

Pyo JY, Choi SE, Shin E, Koo J, Hong S

BACKGROUND: When differential diagnosis is difficult in thyroid follicular lesions with overlapping histological features, the immunohistochemical staining can help confirm the diagnosis. We aimed to evaluate the effectiveness of rapid...
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Subsequent Thrombotic Outcomes in Patients with Ischemic Stroke with Antiphospholipid Antibody Positivity

Pyo JY, Jung SM, Lee SW, Song JJ, Lee SK, Park YB

PURPOSE: International consensus criteria for antiphospholipid syndrome (APS) require persistently positive antiphospholipid antibodies (aPL) and medium or high titers in association with clinical manifestations. However, the clinical relevance of persistence...
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Thyroid Fine-Needle Aspiration Cytology Practice in Korea

Cha YJ, Pyo JY, Hong S, Seok JY, Kim KJ, Han JY, Bae JM, Kwon HJ, Kim Y, Min KW, Oak S, Chang S

We reviewed the current status of thyroid fine-needle aspiration cytology (FNAC) in Korea. Thyroid aspiration biopsy was first introduced in Korea in 1977. Currently, radiologists aspirate the thyroid nodule under...
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Extremely Well-Differentiated Papillary Thyroid Carcinoma Resembling Adenomatous Hyperplasia Can Metastasize to the Skull: A Case Report

Pyo JY, Kim J, Choi SE, Shin E, Yang SW, Park CS, Kim SM, Hong S

We describe herein histologic, immunohistochemical, and molecular findings and clinical manifestations of a rare case of an extremely well differentiated papillary thyroid carcinoma (EWD-PTC). Similarly, it is also difficult to...
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Clinicopathologic Correlations of E-cadherin and Prrx-1 Expression Loss in Hepatocellular Carcinoma

Yi K, Kim H, Chung Y, Ahn H, Sim J, Wi YC, Pyo JY, Song YS, Paik SS, Oh YH

BACKGROUND: Developing predictive markers for hepatocellular carcinoma (HCC) is important, because many patients experience recurrence and metastasis. Epithelial to mesenchymal transition (EMT) is a developmental process that plays an important...
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The Presence of Anti-ribonucleoprotein at Diagnosis Is Associated with the Flare during the First Follow-up Year in Korean Patients with Systemic Lupus Erythematosus

Kim DS, Pyo JY, Byun SJ, Ahn SS, Song J, Park YB, Lee SK, Lee SW

OBJECTIVE: The aim of this study was to examine whether the presence of anti-ribonucleoprotein (anti-RNP) antibodies at diagnosis is associated with systemic lupus erythematosus (SLE) flares in newly diagnosed patients...
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Bioballs Causing Asymptomatic or Recurrent Acute Rhinosinusitis: Two Cases

Kim HD, Lee DW, Pyo JY, Oh YH, Cho SH

A variety of intrinsic and extrinsic factors have been studied to explain the pathogenesis of rhinosinusitis. Recently biofilms are emerging as an important cause. Biofilms are highly organized structures composed...
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Repeated Panniculitis Induced by Pegylated Interferon Alpha 2a in a Patient with Chronic Hepatitis C

Song JS, Sohn JH, Jeong JY, Min JH, Choi WS, Kim OZ, Pyo JY

Pegylated interferon alpha (PEG-IFN-α) is widely used to treat chronic hepatitis C in combination with ribavirin. Many adverse effects of PEG-IFN-α, such as hematologic, psychologic, dermatologic, immunologic, and other abnormalities,...
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MRI Findings of a Large Pedunculated Eccrine Poroma: A Case Report

Kim SH, Ryu JA, Lee JI, Pyo JY, Oh YH, Lee CM

Eccrine poroma is a rare benign neoplasm of the eccrine sweat gland that usually presents as a small skin lesion such as a papule or nodule. This benign tumor has...
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Brain meningioma in a patient with systemic lupus erythematosus

Yoo BW, Ahn SS, Pyo JY, Byun SJ, Song JJ, Park YB, Lee SK, Song JS, Lee SW

Brain meningioma, the most common benign brain tumor, has been reported to account for 13-26% of all intracranial tumors, with a crude incidence rate of 2.3 per 100,000 persons for...
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Significance of the Extracapsular Spread of Metastatic Lymph Nodes in Papillary Thyroid Carcinoma

Park CH, Song CM, Ji YB, Pyo JY, Yi KJ, Song YS, Park YW, Tae K

OBJECTIVES: The extracapsular spread (ECS) of metastatic lymph nodes is associated with aggressive tumor behavior, and is regarded as a major risk factor for local recurrence in patients with head...
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Intrathoracic Desmoid Tumor Presenting as Multiple Lung Nodules 13 Years after Previous Resection of Abdominal Wall Desmoid Tumor

Koo GW, Chung SJ, Kwak JH, Oh CK, Park DW, Kwak HJ, Moon JY, Kim SH, Sohn JW, Yoon HJ, Shin DH, Park SS, Oh YH, Pyo JY, Kim TH

Desmoid tumors are rare soft tissue tumors considered to have locally infiltrative features without distant metastasis until now. Although they are most commonly intraabdominal, very few cases have extra-abdominal locations....
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Gastric Syphilis and Membranous Glomerulonephritis

Roh M, Sohn JH, Kim TY, Kim SJ, Kim JS, Chung SJ, Pyo JY, Oh YH

Syphilis is a chronic systemic infectious disease caused by the bacterium Treponema pallidum. Gastric involvement and nephrotic syndrome are uncommon but well documented complications of syphilis, but the co-occurrence of...
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Pulmonary Foreign Body Granulomatosis in Dental Technician

Chung SJ, Koo GW, Park DW, Kwak HJ, Yhi JY, Moon JY, Kim SH, Sohn JW, Yoon HJ, Shin DH, Park SS, Pyo JY, Oh YH, Kim TH

Occupational lung diseases are caused by several toxic substances including heavy metals; however, the exact pathologic mechanisms remain unknown. In the workplace, dental technicians are often exposed to heavy metals...
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A Case of Significant Endobronchial Injury due to Recurrent Iron Pill Aspiration

Kwak JH, Koo GW, Chung SJ, Park DW, Kwak HJ, Moon JY, Kim SH, Sohn JW, Yoon HJ, Shin DH, Park SS, Pyo JY, Oh YH, Kim TH

Gastric mucosal damage by iron pills is often reported. However, iron pill aspiration is uncommon. Oxidation of the impacted iron pill causes bronchial mucosal damage that progresses to chronic bronchial...
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Delta Neutrophil Index as an Early Marker for Differential Diagnosis of Adult-Onset Still's Disease and Sepsis

Park HJ, Ha YJ, Pyo JY, Park YB, Lee SK, Lee SW

PURPOSE: To investigate clinical implications of delta neutrophil index (DNI) to discriminate adult onset Still's disease (AOSD) from sepsis. MATERIALS AND METHODS: We reviewed the medical records of 13 patients with...
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Dermatomyositis Associated with Gallbladder Cancer

Park JS, Pyo JY, Park YB, Lee SK, Lee SW

Dermatomyositis, an idiopathic inflammatory myopathy with characteristic skin manifestations, is associated with several types of cancer. Only three cases of gallbladder cancer with dermatomyositis have been reported worldwide, and none...
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